Nanomedicine for anti-cancer therapy

Bioprospecting

FARM290 Generell farmakologi

FARM293 Farmakologi II

Doktorgradsavhandling

• Lars Herfindal (2006). Apoptosis modulating and anti-thrombotic activities from marine micro-organisms. (ekstern lenke)

Fagartikkel

• Angeliki Barouti; Lars Herfindal; Monica Jordheim (2021). The under-explored chemistry of seaweeds. (ekstern lenke)

Forelesning

• Monica Jordheim; Lars Herfindal (2026). From molecules to possibilities: Monica and Lars explore future medicines from the ocean. (ekstern lenke)
• Angeliki Barouti; Monica Jordheim; Lars Herfindal (2022). Targeting high-value products from the epiphytes of Laminaria hyperborea. (ekstern lenke)

Forskningsrapport

• Hanne Hagland; Frode Selheim; TJ Keen et al. (2005). The cAMP Receptors Epac and PKA synergize to induce PC12 cell neuritogenesis and to protect against apoptosis. (ekstern lenke)

Konferanseabstrakt

• Lene Elisabeth Myhren; IM Nilsen; Valerie Nicolas et al. (2013). Development and in vitro efficacy of liposomes carrying anthracyclines and emetine for enhanced therapeutic effect. (ekstern lenke)
• J Jokela; W Matti; Lars Herfindal et al. (2008). Bioactive peptides from cyanobacteria. (ekstern lenke)

Konferanseforedrag

• Aase Merethe Raddum; Quynh Bao Truong Le; Wei Wang et al. (2023). Improving student confidence in lab learning through problem-based learning. (ekstern lenke)
• Aase Merethe Raddum; Mirey Alfarah; Quynh Bao Truong Le et al. (2023). Lab som Læringsarena. (ekstern lenke)
• Marita Hoang Anh Vu; Lars Herfindal; Ole Johan Juvik et al. (2017). Rome –en unik kilde til nye antileukemi naturprodukter. (ekstern lenke)
• Eirik Færøy Sæbø; Julia Endresen Storesund; Lars Herfindal et al. (2017). Isolation and screening of novel planctomycetes from Svarthamar ice Cave, Northern Norway. (ekstern lenke)
• Lars Herfindal (2011). Bioactive compounds from culturable marine microorganisms. (ekstern lenke)
• S. Stensun; Kimberley Hatfield; Gjert Knutsen et al. (2003). Drug potentials from marine cyanobacteria and microalgae from Norwegian waters. (ekstern lenke)
• Kari Espolin Fladmark; Lars Herfindal; Stein Ove Døskeland et al. (2002). Bioactive compounds from cyanobacteria. (ekstern lenke)
• Lars Herfindal; Frode Selheim; Gjert Knutsen et al. (2002). New apoptosis-modulating substances from marine microalgae. (ekstern lenke)
• Lars Herfindal; Masaru Tanaka; Ivar Rønnestad (1999). Effect of feeding Artemia enriched with free phenylalanine and tyrosine to larval Japanese flounder. (ekstern lenke)

Konferanseposter

• Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bendik Auran Rathe et al. (2023). Romeforgiftning av storfe –Et århundregammelt problem mot sin løsning. (ekstern lenke)
• Angeliki Barouti; Monica Jordheim; Lars Herfindal (2023). EPIPHYTES OF LAMINARIA: A PROMISING SOURCE OF ANTIMICROBIAL AND CYTOTOXIC COMPOUNDS. (ekstern lenke)
• Angeliki Barouti; Monica Jordheim; Lars Herfindal (2023). EPIPHYTES OF LAMINARIA: A PROMISING SOURCE OF ANTIMICROBIAL AND CYTOTOXIC COMPOUNDS. (ekstern lenke)
• Constance De Montlaur; Reidun Æsøy; Annette Brenner et al. (2022). Precision medicine in childhood cancer - a representative case of neuroblastoma. (ekstern lenke)
• Abdelnour Alhourani; Hanne Røland Hagland; Jan-Lukas Førde et al. (2019). Preparation of non-oxidized graphene nanosheets for drug delivery. (ekstern lenke)
• Elvar Örn Viktorsson; Ove Alexander Høgmoen Åstrand; Tore Bonge-Hansen et al. (2016). Total synthesis and initial antileukemic evaluation of the phenazine 5,10-dioxide natural products iodinin and myxin. (ekstern lenke)
• Bruno Fouillet; Abdelhamid Nacereddine; Nina Lied Larsen et al. (2015). Indeno[1,2-b]indole derivatives as protein kinase CK2 inhibitors: comparison of in silico models for Tox prediction. (ekstern lenke)
• Lars Herfindal; Lene Elisabeth Myhren; Ida Mostrøm Nilssen et al. (2012). Development and in vitro efficacy of liposomes carrying anthracyclines and emetine for enhanced therapeutic effect. (ekstern lenke)
• maria Perander; Trine Stiberg; Lene Elisabeth Myhren et al. (2011). Characterization of cytotoxic activities in extracts from two marine invertebrates. (ekstern lenke)
• Lars Herfindal; Lene Elisabeth Myhren; Rune Kleppe et al. (2010). Liver specific transporters of microcystins as a tool to find novel inhibitors of OATP1B1 and OATP1B3. (ekstern lenke)
• Hanne Jørgensen; Kristin F. Degnes; Håvard Sletta et al. (2009). The biosynthesis of macrolactam BE-14106: a new way of generating an aminoacyl starter unit. (ekstern lenke)
• S Prestegard; Kimberley Joanne Hatfield; G. Knutsen et al. (2005). Searching cyanobacteria and microalgae from Norwegian waters for drug candidates. (ekstern lenke)
• Lars Herfindal; Frode Selheim; Kjetil Aursland et al. (2002). Effects of a new bioactive substance from a marine microalga on mammalian cells. (ekstern lenke)
• Lars Herfindal; Frode Selheim; Gjert Knutsen et al. (2001). New apoptosis-modulating substances from marine microalgae. (ekstern lenke)
• Lars Herfindal; Camilla Krakstad; Frode Selheim et al. (2001). TWO NOVEL APOPTOSIS-MODULATION SUBSTANCES ISOLATED FROM MARINE MICRO-ALGAE. (ekstern lenke)

Lederartikkel

• Frode Selheim; Lars Herfindal (2016). Editorial: Toward Personalized Treatment for Acute Myeloid Leukemia. (ekstern lenke)
• Frode Selheim; Lars Herfindal (2016). Toward personalized treatment for acute myeloid leukemia. (ekstern lenke)

Masteroppgave

• Silje Skrede; Anette Sivertsen; Lars Herfindal (2023). Zebrafish Larvae as a Model Organism to Study Biotransformation. (ekstern lenke)
• Maren Sukke Sætrang; Lars Herfindal; Silje Skrede (2022). Electromembrane extraction of immunosuppressants. (ekstern lenke)
• Anne Oldeide Hay; Silje Skrede; Lars Herfindal (2021). Electromembrane extraction of methotrexate and its metabolites. (ekstern lenke)
• Lars Herfindal; Martina Stipic; Trond T. Serkland et al. (2020). Drug transport in blood: Lipoproteins as transporters of psychotropic drugs. (ekstern lenke)
• Ingeborg Nerbø Reiten; Lars Herfindal; Sarah Marie Vie Furevik (2020). Zebrafish Larvae as a Model to Study Doxorubicin-Induced Cardiotoxicity. (ekstern lenke)
• Bendik Auran Rathe; Lars Herfindal; Torgils Fossen (2019). Antileukemia activity of plant natural products and hemisynthetic analogs. (ekstern lenke)
• Tuva Torblå Bakke; Lars Herfindal (2019). Zebrafish Larvae as a Model to Study Doxorubicin-Induced Cardiotoxicity. (ekstern lenke)
• Edvin Tang Gundersen; Lars Herfindal; Stein Ove Doskeland (2016). The production and characterization of drug-loaded liposomal and PLGA nanocarriers for targeted treatment of acute myeloid leukemia. (ekstern lenke)
• Fredrik Gullaksen Johannessen; Aurora Martinez; Maria Teresa Bezem et al. (2016). The efficiency of maltodextrin and porous silicon nanoparticles for the in vitro and in vivo stabilization of tyrosine hydroxylase. (ekstern lenke)
• Sarah Marie Vie Furevik; Lars Herfindal; Stein Ove Doskeland (2015). The role of Epac1 in endothelial barrier function Fluorescence intensity measurements of nano capsules in Wnt1-induced breast cancer. (ekstern lenke)
• Ida Mostrøm Nilssen; Stein Ove Doskeland; Lars Herfindal (2012). In vitro validation of multifunctional liposomes for leukaemia and prostate cancer therapy - the folate receptor and the prostate-specific membrane antigen as targets for drug delivery. (ekstern lenke)
• Silje Milankovic; Stein Ove Doskeland; Lars Herfindal et al. (2012). In vivo biodistribution of fluorescent nanocolloids intended for drug delivery - Evaluation of PEGylation state and fluorophore incorporation approach.. (ekstern lenke)
• Gyrid Nygård; Lars Herfindal; Stein Ove Doskeland (2008). Bioactive compounds from marine microorganisms: search for anti-leukemic drugs and finding mechanisms of action. (ekstern lenke)
• Maria Helen Kurki Larsen; Frode Selheim; Lars Herfindal (2008). Platelet inhibitory compounds from marine microorganisms. (ekstern lenke)

Medieintervju

• Ivar Lid Riise; Mathias Kleiveland; Heidi Lie Andersen et al. (2023). Dreper kreftceller med hageplanter. (ekstern lenke)
• Guri Gunnes Oppegård; Lise Øvreås; Lars Herfindal et al. (2019). Mikrobejakten. Langt inne i en isgrotte i Nordland har forskerne lett ettr ny antibiotika. Det haster å hente ut ukjente bakteriestammer, for verdens minste organismer står if are for å smelte bort. (ekstern lenke)

Populærvitenskapelig artikkel

• Lars Herfindal; Ida Mostrøm Nilssen; Silje Milankovic (2012). Nanokolloidar som verkty for å betra distribusjon av legemiddel. (ekstern lenke)
• Siv Kristin Prestegard; Lars Herfindal (2004). Havet som apotek. (ekstern lenke)
• Sigurd Tonheim; Lars Herfindal; I Rønnestad (2000). Anrikning av vannløselige komponenter i Artemia. (ekstern lenke)

Vitenskapelig artikkel

• Théo Frazier; Elisabeth Pereira; Reidun Æsøy et al. (2026). Synthesis, anti-cancer activity, Pim-3 inhibitory potency and zebrafish larvae toxicity evaluation of indolopyrazolocarbazole derivatives. (ekstern lenke)
• Angeliki Barouti; Le Ba Vinh; Lars Herfindal et al. (2026). Marine Bromophenols from Laminaria hyperborea’s Epiphytic Biomass: Chemical Profiling, Cytotoxicity, and Antioxidant Activity. (ekstern lenke)
• Edvin Tang Gundersen; Zhiqiang Wang; Jan-Lukas Førde et al. (2025). Repurposing chlorpromazine for anti-leukaemic therapy with the drug-in-cyclodextrin-in-liposome nanocarrier platform. (ekstern lenke)
• Ingeborg Nerbø Reiten; Reidun Æsøy; Jan-Lukas Førde et al. (2025). Phenazine 5,10-dioxide analogues as potential therapeutics in AML: Efficacy on patient-derived blasts, in zebrafish larvae xenografts and synergy with venetoclax. (ekstern lenke)
• Goraksha Machhindra Khose; Siva Krishna Vagolu; Reidun Aesoy et al. (2025). Functionalized regioisomers of the natural product phenazines myxin and iodinin as potent inhibitors of Mycobacterium tuberculosis and human acute myeloid leukemia cells. (ekstern lenke)
• Christelle Marminon; Christian Werner; Alexander Gast et al. (2025). Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2. (ekstern lenke)
• Ingeborg Nerbø Reiten; Francis Giraud; Tuva Torblå Augedal et al. (2025). Liposomes loaded with daunorubicin and an emetine prodrug for improved selective cytotoxicity towards acute myeloid leukaemia cells. (ekstern lenke)
• Aase Merethe Raddum; Quynh Bao Truong Le; Lars Herfindal et al. (2025). Fostering student agency and confidence through problem-based learning and cognitive reflection in the pharmaceutics laboratory. (ekstern lenke)
• Luc Augis; Ingeborg Nerbø Reiten; Jan-Lukas Førde et al. (2024). Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances. (ekstern lenke)
• Angeliki Barouti; Lars Herfindal; Siva Krishna Vagolu et al. (2024). Evaluation of the cytotoxic and antimicrobial potential of epiphytic biomass obtained from Laminaria hyperborea biorefinery side-streams. (ekstern lenke)
• Anette Lodvir Hemsing; Jan-Lukas Førde; Håkon Reikvam et al. (2024). The Rac1-inhibitor EHop-016 attenuates AML cell migration and enhances the efficacy of daunorubicin in MOLM-13 transplanted zebrafish larvae. (ekstern lenke)
• Bjørn Tobiassen Heieren; Anja Strandvoll Dyrdal; Lars Herfindal et al. (2024). Cytotoxic Natural Products from Cryptomeria japonica (Thunb. ex L.) D.Don. (ekstern lenke)
• Théo Frazier; Elisabeth Pereira; Reidun Aesoy et al. (2024). Synthesis, kinase inhibition and anti-leukemic activities of diversely substituted indolopyrazolocarbazoles. (ekstern lenke)
• Jan-Lukas Førde; Abdelnour Alhourani; Tian Carey et al. (2024). Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation. (ekstern lenke)
• Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bjarte Holmelid et al. (2024). Cytotoxic Natural Products from the Jurassic Relict Osmunda regalis L.. (ekstern lenke)
• Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Heidi Lie Andersen et al. (2023). Cytotoxic Natural Products Isolated from Cryptogramma crispa (L.) R. Br.. (ekstern lenke)
• Jan-Lukas Førde; Lars Herfindal; Kjell-Morten Myhr et al. (2023). Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro. (ekstern lenke)
• Etienne Auvert; Reidun Aesoy; Francis Giraud et al. (2022). Synthesis of new pyrazolo[4,3-a]phenanthridine Pim-1 inhibitors and evaluation of their cytotoxic activity towards the MOLM-13 acute myeloid leukemia cell line. (ekstern lenke)
• Jan-Lukas Førde; Ingeborg Nerbø Reiten; Kari Espolin Fladmark et al. (2022). A new software tool for computer assisted in vivo high-content analysis of transplanted fluorescent cells in intact zebrafish larvae. (ekstern lenke)
• Ronja Bjørnstad; Ingeborg Nerbø Reiten; Kaja Skålnes Knudsen et al. (2022). A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect. (ekstern lenke)
• Abdelnour Alhourani; Jan-Lukas Førde; Mojdeh Nasrollahzadeh et al. (2022). Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish. (ekstern lenke)
• Anne Oldeide Hay; Roger Trones; Lars Herfindal et al. (2022). Determination of methotrexate and its metabolites in human plasma by electromembrane extraction in conductive vials followed by LC-MS/MS. (ekstern lenke)
• Rune Slimestad; Bendik Auran Rathe; Reidun Aesoy et al. (2022). A novel bicyclic lactone and other polyphenols from the commercially important vegetable Anthriscus cerefolium. (ekstern lenke)
• Abdelnour Alhourani; Jan-Lukas Førde; Lutz Andreas Eichacker et al. (2021). Improved pH-Responsive Release of Phenformin from Low-Defect Graphene Compared to Graphene Oxide. (ekstern lenke)
• Elvar Örn Viktorsson; Reidun Aesoy; Sindre Støa et al. (2021). New prodrugs and analogs of the phenazine 5,10-dioxide natural products iodinin and myxin promote selective cytotoxicity towards human acute myeloid leukemia cells. (ekstern lenke)
• Yagut Allahverdiyeva; Eva-Mari Aro; Bert van Bavel et al. (2021). NordAqua, a Nordic Center of Excellence to develop an algae-based photosynthetic production platform. (ekstern lenke)
• Kari Skjånes; Reidun Aesoy; Lars Herfindal et al. (2021). Bioactive peptides from microalgae: Focus on anti-cancer and immunomodulating activity. (ekstern lenke)
• Edvin Tang Gundersen; Jan-Lukas Førde; Benedicte Sjo Tislevoll et al. (2021). Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation. (ekstern lenke)
• Zhiqiang Wang; David Landy; Christina Sizun et al. (2020). Cyclodextrin Complexation Studies as the First Step for Repurposing of Chlorpromazine. (ekstern lenke)
• Mohummad Aminur Rahman; Jorunn Brekke; Victoria Smith Arnesen et al. (2020). Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study. (ekstern lenke)
• Agnete Engelsen; Katarzyna Wnuk-Lipinska; Sébastien Bougnaud et al. (2020). AXL is a driver of stemness in normal mammary gland and breast cancer. (ekstern lenke)
• Eirik Johansson Solum; Trond Vidar Hansen; Reidun Aesoy et al. (2020). New CDK8 inhibitors as potential anti-leukemic agents – Design, synthesis and biological evaluation. (ekstern lenke)
• Kathrine Sivertsen Åsrud; Line Pedersen; Reidun Aesoy et al. (2019). Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy. (ekstern lenke)
• Anu Humisto; Jouni Jokela; Knut Teigen et al. (2019). Characterization of the interaction of the antifungal and cytotoxic cyclic glycolipopeptide hassallidin with sterol-containing lipid membranes. (ekstern lenke)
• Ayaan Hamdi Haji Ibrahim; Lars Herfindal; Bendik Auran Rathe et al. (2019). A novel poly-oxygenated flavone glucoside from aerial parts of the Brazilian plant Neoglaziovia variegata (Bromeliaceae). (ekstern lenke)
• Tania Keiko Shishido; Rafael Vicentini Popin; Jouni Jokela et al. (2019). Dereplication of Natural Products with Antimicrobial and Anticancer Activity from Brazilian Cyanobacteria. (ekstern lenke)
• Ronja Bjørnstad; Reidun Aesoy; Øystein Bruserud et al. (2019). A kinase inhibitor with anti-Pim kinase activity is a potent and selective cytotoxic agent toward acute myeloid leukemia. (ekstern lenke)
• Rita Calisto; Eirik Færøy Sæbø; Julia Endresen Storesund et al. (2019). Anticancer activity in Planctomycetes. (ekstern lenke)
• Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bendik Auran Rathe et al. (2019). Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. (ekstern lenke)
• Trond T. Serkland; Jan Schjøtt; Jon Andsnes Berg et al. (2019). Short communication: Distribution of psychotropic drugs into lipoproteins. (ekstern lenke)
• Maria Teresa Bezem; Fredrik Gullaksen Johannessen; Kunwar Jung K C et al. (2018). Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. (ekstern lenke)
• Anthony Prandina; Lars Herfindal; Sylvie Radix et al. (2018). Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles. (ekstern lenke)
• Gyrid Nygaard; Lars Herfindal; Kathrine Sivertsen Åsrud et al. (2017). Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. (ekstern lenke)
• Elvar Örn Viktorsson; Bendik Melling Grøthe; Reidun Aesoy et al. (2017). Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. (ekstern lenke)
• Anu Humisto; Lars Herfindal; Jouni Jokela et al. (2016). Cyanobacteria as a source for novel anti-leukemic compounds. (ekstern lenke)
• Lasse Evensen; Patrick Lie Johansen; Gerbrand Koster et al. (2016). Zebrafish as a model system for characterization of nanoparticles against cancer. (ekstern lenke)
• Marita Hoang Anh Vu; Lars Herfindal; Ole-Johan Juvik et al. (2016). Toxic aromatic compounds from fruits of Narthecium ossifragum L.. (ekstern lenke)
• Francis Giraud; Marion Bourhis; Edris Ebrahimi et al. (2015). Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells. (ekstern lenke)
• Zouhair Bouaziz; Samar Issa; Jacques Gentili et al. (2015). Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds. (ekstern lenke)
• Liwei Liu; Jouni Jokela; Lars Herfindal et al. (2014). 4-methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides. (ekstern lenke)
• Gyrid Nygaard; Lars Herfindal; Reidun Kristin Kopperud et al. (2014). Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. (ekstern lenke)
• Liwei Liu; Lars Herfindal; Jouni Jokela et al. (2014). Cyanobacteria from terrestrial and marine sources contain apoptogens able to overcome chemoresistance in acute myeloid leukemia cells. (ekstern lenke)
• Lene Elisabeth Myhren; Ida Mostrøm Nilssen; Valérie Nicolas et al. (2014). Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia. (ekstern lenke)
• Siv Kristin Prestegard; Gjert Knutsen; Lars Herfindal (2014). Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. (ekstern lenke)
• Francis Giraud; Marion Bourhis; Lionel Nauton et al. (2014). New N-1,N-10 bridged pyrrolo[2,3-α]carbazole-3-carbaldehydes: synthesis and biological activities. (ekstern lenke)
• Lars Herfindal; Camilla Krakstad; Lene Elisabeth Myhren et al. (2014). Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. (ekstern lenke)
• Håvard Sletta; Kristin Fløgstad Degnes; Lars Herfindal et al. (2014). Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment. (ekstern lenke)
• Siv Kristin Prestegard; Gjert Knutsen; Lars Herfindal (2014). Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. (ekstern lenke)
• Lars Herfindal; Lene Elisabeth Myhren; Bjørn Tore Gjertsen et al. (2013). Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen. (ekstern lenke)
• Lene Elisabeth Myhren; Gyrid Nygaard; Gro Gausdal et al. (2013). Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells. (ekstern lenke)
• Gro Gausdal; Anita Wergeland; Jørn Skavland et al. (2013). Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. (ekstern lenke)
• Lars Herfindal; Gyrid Nygaard; Reidun Kristin Kopperud et al. (2013). Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets. (ekstern lenke)
• Jouni Jokela; Linn Silje Wathne Oftedal; Lars Herfindal et al. (2012). Anabaenolysins, novel cytolytic lipopeptides from benthic anabaena cyanobacteria. (ekstern lenke)
• Linn Silje Wathne Oftedal; Lene Elisabeth Myhren; Jouni Jokela et al. (2012). The lipopeptide toxins Anabaenolysin A and B target biological membranes in a cholesterol-dependent manner. (ekstern lenke)
• Linn Silje Wathne Oftedal; Kaja Helvik Skjærven; Rosie Theresa Coyne et al. (2011). The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity. (ekstern lenke)
• Lars Herfindal; Lene Elisabeth Myhren; Rune Kleppe et al. (2011). Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and 1B1. (ekstern lenke)
• Jouni Jokela; Lars Herfindal; Matti Wahlsten et al. (2010). A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins. (ekstern lenke)
• Linn Silje Wathne Oftedal; Frode Selheim; Matti Wahlsten et al. (2010). Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes. (ekstern lenke)
• Hanne Jørgensen; Kristin Degnes; Håvard Sletta et al. (2009). Biosynthesis of Macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit. (ekstern lenke)
• Siv Kristin Prestegard; Linn Silje Wathne Oftedal; Rosie Theresa Coyne et al. (2009). Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity. (ekstern lenke)
• Lars Herfindal; Franciszek Kasprzykowski; Frank Schwede et al. (2009). Acyloxymethyl esterification of Nodularin-R and Microcystin-LA produces inactive protoxins that become reactivated and produce apoptosis inside intact cells. (ekstern lenke)
• Rosário F. Martins; Miguel F. Ramos; Lars Herfindal et al. (2008). Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and synechococcus. (ekstern lenke)
• Camilla Krakstad; Lars Herfindal; Bjørn Tore Gjertsen et al. (2006). CaM-kinasell-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation. (ekstern lenke)
• Lars Herfindal; Frode Selheim; Linn Silje Wathne Oftedal et al. (2005). A high proportion of Baltic Sea benthic cyanobacterial isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes. (ekstern lenke)
• Frode Selheim; Lars Herfindal; Rosario Martins et al. (2005). Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast. (ekstern lenke)
• Øystein Bruserud; Nils Glenjen; Bjørn Tore Gjertsen et al. (2002). Use of marine toxins in combination with cytotoxic drugs for induction of apoptosis in acute myelogenous leukaemia cells. (ekstern lenke)
• Frode Selheim; Lars Herfindal; Gjert Knutsen et al. (2001). Alterations in platelet phospholipid metabolism by substances from a marine microalgae. (ekstern lenke)

Vitenskapelig bokkapittel

• Gro Gausdal; Camilla Krakstad; Lars Herfindal et al. (2007). Serine/Threonine Protein Phosphatases in Apoptosis. (ekstern lenke)

Vitenskapelig litteraturgjennomgang

• David P. Fewer; Jouni Jokela; Lassi Heinilä et al. (2021). Chemical diversity and cellular effects of antifungal cyclic lipopeptides from cyanobacteria. (ekstern lenke)
• Aditi Singh; Nikolai Norevik Myklebust; Sarah Marie Vie Furevik et al. (2019). Immunoliposomes in acute myeloid leukaemia therapy. An overview of possible targets and obstacles. (ekstern lenke)
• Félix Sauvage; Gillian Barratt; Lars Herfindal et al. (2016). The use of nanocarriers in acute myeloid leukaemia therapy: Challenges and current status. (ekstern lenke)
• Rune Kleppe; Lars Herfindal; Stein Ove Doskeland (2015). Cell Death inducing microbial protein phosphatase inhibitors-mechanisms of action. (ekstern lenke)
• Lars Herfindal; Frode Selheim (2006). Microcystin produces disparate effects on liver cells in a dose dependent manner. (ekstern lenke)

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