- o.oppegaard@uib.no
- Visitor address
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Haukeland universitetssykehus, Laboratoriebygget
5009 Bergen - Postal address
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P.O. Box 7804NO-5020 BergenNorway
Research
Oddvar Oppegaard is senior physician at the Department of Infectious Diseases, Haukeland University Hospital and an assistant professor at the Department of Clinical Science, UoB. Important fields of research have been serious streptococcal infections with the main focus on bacterial virulence, resistance and pathogenesis. The work includes bioinformatic whole genome analysis, as well as genetic characterization and manipulation of bacterial strains in the laboratory. Oppegaard and the streptococcus research group at the University of Bergen and Haukeland University Hospital are currently participating in the PERMIT and PERAID projects (https://permedinfect.com/) funded by Nordforsk and the EU. These projects aim to promote research into personalized medicine (PM) in serious infectious diseases, especially life-threatening necrotizing soft tissue infections (NSTI) and sepsis.
Publications
Academic article
- Marta Wojnowska; Takeaki Wajima; Tamas Yelland et al. (2025). Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm. (external link)
- Oddvar Oppegaard; Haima Mylvaganam; Bård Reiakvam Kittang (2015). Beta-haemolytic group A, C and G streptococcal infections in Western Norway: a 15-year retrospective survey. (external link)
- Oddvar Oppegaard; Steinar Skrede; Haima Mylvaganam et al. (2020). Emerging threat of antimicrobial resistance in β-hemolytic streptococci. (external link)
- Eirik Jovall Nybakken; Oddvar Oppegaard; Marianne Gilhuus et al. (2020). Identification of Streptococcus dysgalactiae using matrix-assisted laser desorption/ionization-time of flight mass spectrometry; refining the database for improved identification. (external link)
- Oddvar Oppegaard; Marte Glambek; Dag Harald Skutlaberg et al. (2023). Streptococcus dysgalactiae Bloodstream Infections, Norway, 1999-2021. (external link)
- Helena Bergsten; Martin Bruun Madsen; Francois Bergey et al. (2020). Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections. (external link)
- Trond Bruun; Eivind Rath; Martin Bruun Madsen et al. (2020). Risk factors and Predictors of Mortality in Streptococcal Necrotizing Soft-Tissue Infections: A Multicenter Prospective Study. (external link)
- Marie Bjørbak Alnæs; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2023). A new pathway for penicillin delabeling in Norway. (external link)
- Oddvar Oppegaard; Brita Skodvin; Anne-Kristine Halse et al. (2013). CD64 as a potential biomarker in septic arthritis. (external link)
- Trond Bruun; Oddvar Oppegaard; Karl Ove Hufthammer et al. (2016). Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors. (external link)
- Stina Jordal; Marte Glambek; Oddvar Oppegaard et al. (2015). New tricks from an old cow: infective endocarditis caused by Streptococcus dysgalactiae subsp. dysgalactiae. (external link)
- Marita Torrissen Mårli; Oddvar Oppegaard; Davide Porcellato et al. (2024). Genetic modification of Streptococcus dysgalactiae by natural transformation. (external link)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2014). Sequence diversity of sicG among group C and G Streptococcus dysgalactiae subspecies equisimilis isolates associated with human infections in western Norway. (external link)
- Marie Bjørbak Alnæs; Brita Skodvin; Jan Anker Jahnsen et al. (2024). “What if the patient has a severe reaction, and it is my fault?” A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling. (external link)
- Lea A. Tölken; Janine V. Neufend; Oddvar Oppegaard et al. (2024). Streptokinase reduces Streptococcus dysgalactiae subsp. equisimilis biofilm formation. (external link)
- Nikolai Siemens; Bård Reiakvam Kittang; Bhavya Chakrakodi et al. (2015). Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections. (external link)
- Marte Glambek; Morten Kjos; Marita Torrissen MÃ¥rli et al. (2025). TrexAB, a novel tetracycline resistance determinant in Streptococcus dysgalactiae. (external link)
- Sanjeevan Jahagirdar; Lorna Morris; Nirupama Benis et al. (2022). Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections. (external link)
- Trond Bruun; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2016). Etiology of cellulitis and clinical prediction of streptococcal disease: A prospective study. (external link)
- Eivind Rath; Steinar Skrede; Oddvar Oppegaard et al. (2020). Non-purulent skin and soft tissue infections: predictive power of a severity score and the appropriateness of treatment in a prospective cohort. (external link)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2017). Clinical and molecular characteristics of infective β-hemolytic streptococcal endocarditis. (external link)
- Marit Smistad; Tore Tollersrud; Lars Austbø et al. (2021). Molecular detection and genotype characterization of Streptococcus dysgalactiae from sheep flocks with outbreaks of infectious arthritis. (external link)
- Marie Bjørbak Alnæs; Anne Berit Guttormsen; Ingrid Terreehorst et al. (2025). Norwegian Anaesthesiologist's Perspectives on Perioperative Allergies and Penicillin Allergy Evaluations: A National Survey. (external link)
- Ingunn Gundersen; Trond Bruun; Stian Kreken Almeland et al. (2024). Necrotizing soft tissue infections. (external link)
- Bård Reiakvam Kittang; Veronika Kucharova Pettersen; Oddvar Oppegaard et al. (2017). Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. (external link)
- Maria Karolina Jonsson; Daniel Hammenfors; Oddvar Oppegaard et al. (2015). A 35-year-old woman with influenza A-associated thrombotic thrombocytopenic purpura. (external link)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2018). Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis. (external link)
- Oddvar Oppegaard; Steinar Skrede; Haima Mylvaganam et al. (2016). Temporal trends of β-haemolytic streptococcal osteoarticular infections in western Norway. (external link)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2017). Emergence of a Streptococcus dysgalactiae subspecies equisimilis stG62647-lineage associated with severe clinical manifestations. (external link)
- Alba Kaci; Christine M Jonassen; Steinar Skrede et al. (2023). Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018. (external link)
- Marita Torrissen MÃ¥rli; Magnus Øverlie Arntzen; Jennie Ann Allred et al. (2025). Self-Immunity Towards a Novel Competence-Induced Streptococcal Peptidoglycan Hydrolase is Mediated by a Fem-Transferase-Like Protein. (external link)
- Marte Glambek; Steinar Skrede; Audun Sivertsen et al. (2024). Antimicrobial resistance patterns in Streptococcus dysgalactiae in a One Health perspective. (external link)
- Paul Christoffer Lindemann; Haima Mylvaganam; Oddvar Oppegaard et al. (2022). Case Report: Whole-Genome Sequencing of Serially Collected Haemophilus influenzae From a Patient With Common Variable Immunodeficiency Reveals Within-Host Evolution of Resistance to Trimethoprim-Sulfamethoxazole and Azithromycin After Prolonged Treatment With These Antibiotics. (external link)
- Davide Porcellato; Marit Smistad; Siv Borghild Skeie et al. (2021). Whole genome sequencing reveals possible host species adaptation of Streptococcus dysgalactiae. (external link)
Conference poster
- Marita Torrissen Mårli; Davide Porcellato; Daniel Straume et al. (2022). A study of competence in Streptococcus dysgalactiae by RNA-seq. (external link)
- Marita Torrissen Mårli; Oddvar Oppegaard; Davide Porcellato et al. (2022). An investigation of the competence regulon in Streptococcus dysgalactiae by RNA-seq. (external link)
- Marita Torrissen Mårli; Oddvar Oppegaard; Davide Porcellato et al. (2022). An investigation of the competence regulon of Streptococcus dysgalactiae. (external link)
Study protocol
- Bjørn Blomberg; Nikolai Norevik Myklebust; Oddvar Oppegaard et al. (2025). Randomized trial of nirmatrelvir/ritonavir versus placebo for adults with acute COVID-19 to prevent long COVID: PanoramicNOR Trial | Trials | Full Text. (external link)
- Marie Bjørbak Alnæs; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2025). Examining implementation of the first risk stratification-based programme for evaluating penicillin allergy labels in Western Norway hospitals: a study protocol. (external link)