- E-post
- o.oppegaard@uib.no
- Besøksadresse
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Haukeland universitetssykehus, Laboratoriebygget
5009 Bergen - Postadresse
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Postboks 7804
5020 Bergen
Forskning
Oddvar Oppegaard er overlege ved Infeksjonsseksjonen, Medisinsk Klinikk, Haukeland Universitetssjukehus og 1. amanuensis ved Klinisk institutt 2, UiB. Det viktige forskningsfeltet har vært alvorlige streptokokkinfeksjoner med hovedfokus på bakteriell virulens, resistens og patogenese. Arbeidet omfatter bioinformatisk helgenomanalyse, samt genetisk karakterisering og manipulasjon av bakterielle stammer i laboratoriet. For tiden deltar Oppegaard og streptokokkforskningsgruppen ved Universitetet i Bergen og Haukeland universitetssykehus i PERMIT- og PERAID-prosjektene (https://permedinfect.com/) finansiert av Nordforsk og EU. Disse prosjektene har som mål å fremme forskning på persontilpasset medisin (PM) ved alvorlige infeksjonssykdommer, spesielt livstruende nekrotiserende bløtvevsinfeksjoner (NSTI) og sepsis.
Publikasjoner
Vitenskapelig artikkel
- Marta Wojnowska; Takeaki Wajima; Tamas Yelland et al. (2025). Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm. (ekstern lenke)
- Oddvar Oppegaard; Haima Mylvaganam; Bård Reiakvam Kittang (2015). Beta-haemolytic group A, C and G streptococcal infections in Western Norway: a 15-year retrospective survey. (ekstern lenke)
- Oddvar Oppegaard; Steinar Skrede; Haima Mylvaganam et al. (2020). Emerging threat of antimicrobial resistance in β-hemolytic streptococci. (ekstern lenke)
- Eirik Jovall Nybakken; Oddvar Oppegaard; Marianne Gilhuus et al. (2020). Identification of Streptococcus dysgalactiae using matrix-assisted laser desorption/ionization-time of flight mass spectrometry; refining the database for improved identification. (ekstern lenke)
- Oddvar Oppegaard; Marte Glambek; Dag Harald Skutlaberg et al. (2023). Streptococcus dysgalactiae Bloodstream Infections, Norway, 1999-2021. (ekstern lenke)
- Helena Bergsten; Martin Bruun Madsen; Francois Bergey et al. (2020). Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections. (ekstern lenke)
- Trond Bruun; Eivind Rath; Martin Bruun Madsen et al. (2020). Risk factors and Predictors of Mortality in Streptococcal Necrotizing Soft-Tissue Infections: A Multicenter Prospective Study. (ekstern lenke)
- Marie Bjørbak Alnæs; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2023). A new pathway for penicillin delabeling in Norway. (ekstern lenke)
- Oddvar Oppegaard; Brita Skodvin; Anne-Kristine Halse et al. (2013). CD64 as a potential biomarker in septic arthritis. (ekstern lenke)
- Trond Bruun; Oddvar Oppegaard; Karl Ove Hufthammer et al. (2016). Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors. (ekstern lenke)
- Stina Jordal; Marte Glambek; Oddvar Oppegaard et al. (2015). New tricks from an old cow: infective endocarditis caused by Streptococcus dysgalactiae subsp. dysgalactiae. (ekstern lenke)
- Marita Torrissen Mårli; Oddvar Oppegaard; Davide Porcellato et al. (2024). Genetic modification of Streptococcus dysgalactiae by natural transformation. (ekstern lenke)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2014). Sequence diversity of sicG among group C and G Streptococcus dysgalactiae subspecies equisimilis isolates associated with human infections in western Norway. (ekstern lenke)
- Marie Bjørbak Alnæs; Brita Skodvin; Jan Anker Jahnsen et al. (2024). “What if the patient has a severe reaction, and it is my fault?” A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling. (ekstern lenke)
- Lea A. Tölken; Janine V. Neufend; Oddvar Oppegaard et al. (2024). Streptokinase reduces Streptococcus dysgalactiae subsp. equisimilis biofilm formation. (ekstern lenke)
- Nikolai Siemens; Bård Reiakvam Kittang; Bhavya Chakrakodi et al. (2015). Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections. (ekstern lenke)
- Marte Glambek; Morten Kjos; Marita Torrissen MÃ¥rli et al. (2025). TrexAB, a novel tetracycline resistance determinant in Streptococcus dysgalactiae. (ekstern lenke)
- Sanjeevan Jahagirdar; Lorna Morris; Nirupama Benis et al. (2022). Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections. (ekstern lenke)
- Trond Bruun; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2016). Etiology of cellulitis and clinical prediction of streptococcal disease: A prospective study. (ekstern lenke)
- Eivind Rath; Steinar Skrede; Oddvar Oppegaard et al. (2020). Non-purulent skin and soft tissue infections: predictive power of a severity score and the appropriateness of treatment in a prospective cohort. (ekstern lenke)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2017). Clinical and molecular characteristics of infective β-hemolytic streptococcal endocarditis. (ekstern lenke)
- Marit Smistad; Tore Tollersrud; Lars Austbø et al. (2021). Molecular detection and genotype characterization of Streptococcus dysgalactiae from sheep flocks with outbreaks of infectious arthritis. (ekstern lenke)
- Marie Bjørbak Alnæs; Anne Berit Guttormsen; Ingrid Terreehorst et al. (2025). Norwegian Anaesthesiologist's Perspectives on Perioperative Allergies and Penicillin Allergy Evaluations: A National Survey. (ekstern lenke)
- Ingunn Gundersen; Trond Bruun; Stian Kreken Almeland et al. (2024). Necrotizing soft tissue infections. (ekstern lenke)
- Bård Reiakvam Kittang; Veronika Kucharova Pettersen; Oddvar Oppegaard et al. (2017). Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. (ekstern lenke)
- Maria Karolina Jonsson; Daniel Hammenfors; Oddvar Oppegaard et al. (2015). A 35-year-old woman with influenza A-associated thrombotic thrombocytopenic purpura. (ekstern lenke)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2018). Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis. (ekstern lenke)
- Oddvar Oppegaard; Steinar Skrede; Haima Mylvaganam et al. (2016). Temporal trends of β-haemolytic streptococcal osteoarticular infections in western Norway. (ekstern lenke)
- Oddvar Oppegaard; Haima Mylvaganam; Steinar Skrede et al. (2017). Emergence of a Streptococcus dysgalactiae subspecies equisimilis stG62647-lineage associated with severe clinical manifestations. (ekstern lenke)
- Alba Kaci; Christine M Jonassen; Steinar Skrede et al. (2023). Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018. (ekstern lenke)
- Marita Torrissen MÃ¥rli; Magnus Øverlie Arntzen; Jennie Ann Allred et al. (2025). Self-Immunity Towards a Novel Competence-Induced Streptococcal Peptidoglycan Hydrolase is Mediated by a Fem-Transferase-Like Protein. (ekstern lenke)
- Marte Glambek; Steinar Skrede; Audun Sivertsen et al. (2024). Antimicrobial resistance patterns in Streptococcus dysgalactiae in a One Health perspective. (ekstern lenke)
- Paul Christoffer Lindemann; Haima Mylvaganam; Oddvar Oppegaard et al. (2022). Case Report: Whole-Genome Sequencing of Serially Collected Haemophilus influenzae From a Patient With Common Variable Immunodeficiency Reveals Within-Host Evolution of Resistance to Trimethoprim-Sulfamethoxazole and Azithromycin After Prolonged Treatment With These Antibiotics. (ekstern lenke)
- Davide Porcellato; Marit Smistad; Siv Borghild Skeie et al. (2021). Whole genome sequencing reveals possible host species adaptation of Streptococcus dysgalactiae. (ekstern lenke)
Konferanseposter
- Marita Torrissen Mårli; Davide Porcellato; Daniel Straume et al. (2022). A study of competence in Streptococcus dysgalactiae by RNA-seq. (ekstern lenke)
- Marita Torrissen Mårli; Oddvar Oppegaard; Davide Porcellato et al. (2022). An investigation of the competence regulon in Streptococcus dysgalactiae by RNA-seq. (ekstern lenke)
- Marita Torrissen Mårli; Oddvar Oppegaard; Davide Porcellato et al. (2022). An investigation of the competence regulon of Streptococcus dysgalactiae. (ekstern lenke)
Studieprotokoll
- Bjørn Blomberg; Nikolai Norevik Myklebust; Oddvar Oppegaard et al. (2025). Randomized trial of nirmatrelvir/ritonavir versus placebo for adults with acute COVID-19 to prevent long COVID: PanoramicNOR Trial | Trials | Full Text. (ekstern lenke)
- Marie Bjørbak Alnæs; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2025). Examining implementation of the first risk stratification-based programme for evaluating penicillin allergy labels in Western Norway hospitals: a study protocol. (ekstern lenke)