I work at the Sea Lice Research centre with a focus on the host-parasite interaction of salmon louse (Lepeophtheirus salmonis) and Atlantic salmon as a host. We identify secretory proteins that are deposited from the lice onto the salmon to dampen immune responses.

Techniques that we use includes: transcriptomics, in situ bybridization, histology, SEM, functional studies with primary leucocytes and gene knock down (RNAi) etc

Jeg underviser på fiskehelsestudiet der jeg har emneansvar for BIO275 fiskehistopatologi, samt på BIO101 der jeg har ansvaret for vertebrat zoologi

Vitenskapelig artikkel

• Midtbø, Helena Marie Doherty; Eichner, Christiane; Hamre, Lars Are et al. (2024). Salmon louse labial gland enzymes: implications for host settlement and immune modulation. (ekstern lenke)
• Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf et al. (2024). The ontogeny of lymphoid organs and IgM⁺ B-cells in ballan wrasse (Labrus bergylta) reveals a potential site for extrarenal B-cell lymphopoiesis: The pancreas. (ekstern lenke)
• Etayo, Angela; Bjørgen, Håvard; Hordvik, Ivar et al. (2024). Possible transport routes of IgM to the gut of teleost fish. (ekstern lenke)
• Borchel, Andreas; Eichner, Christiane; Øvergård, Aina-Cathrine (2023). Mining Lepeophtheirus salmonis RNA-Seq data for qPCR reference genes and their application in Caligus elongatus. (ekstern lenke)
• Øvergård, Aina-Cathrine; Eichner, Christiane; Nuñez-Ortiz, Noelia et al. (2023). Transcriptomic and targeted immune transcript analyses confirm localized skin immune responses in Atlantic salmon towards the salmon louse. (ekstern lenke)
• Etayo, Angela; Lie, Kai Kristoffer; Bjelland, Reidun Marie et al. (2023). The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled. (ekstern lenke)
• Gislefoss, Elisabeth; Gamil, Amr Ahmed Abdelrahim; Øvergård, Aina-Cathrine et al. (2023). Identification and characterization of two salmon louse heme peroxidases and their potential as vaccine antigens. (ekstern lenke)
• Øvergård, Aina-Cathrine; Midtbø, Helena Marie Doherty; Hamre, Lars Are et al. (2022). Small, charged proteins in salmon louse (Lepeophtheirus salmonis) secretions modulate Atlantic salmon (Salmo salar) immune responses and coagulation. (ekstern lenke)
• Dalvin, Sussie; Eichner, Christiane; Dondrup, Michael et al. (2021). Roles of three putative salmon louse (Lepeophtheirus salmonis) prostaglandin E2synthases in physiology and host–parasite interactions. (ekstern lenke)
• Dalvin, Sussie; VG Jørgensen, Louise; Kania, Per W. et al. (2020). Rainbow trout Oncorhynchus mykiss skin responses to salmon louse Lepeophtheirus salmonis: From copepodid to adult stage. (ekstern lenke)
• Økland, Arnfinn Lodden; Nylund, Are; Øvergård, Aina-Cathrine et al. (2018). Genomic characterization, phylogenetic position and in situ localization of a novel putative mononegavirus in Lepeophtheirus salmonis. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Grotmol, Sindre et al. (2018). Salmon louse rhabdoviruses: Impact on louse development and transcription of selected Atlantic salmon immune genes.. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Kongshaug, Heidi et al. (2017). RNAi-mediated treatment of two vertically transmitted rhabdovirus infecting the salmon louse (Lepeophtheirus salmonis).. (ekstern lenke)
• Harasimczuk, Ewa; Øvergård, Aina-Cathrine; Grotmol, Sindre et al. (2017). Characterization of three salmon louse (Lepeophtheirus salmonis) genes with fibronectin II domains expressed by tegumental type 1 glands. (ekstern lenke)
• Øvergård, Aina-Cathrine; Eichner, Christiane; Nilsen, Frank et al. (2017). Molecular characterization and functional analysis of a salmon louse (Lepeoptheirus salmonis, Krøyer 1838) heme peroxidase with a potential role in extracellular matrixes. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Harasimczuk, Ewa et al. (2016). Exocrine glands of Lepeophtheirus salmonis (Copepoda: Caligidae): Distribution, developmental appearance, and site of secretion. (ekstern lenke)
• Eichner, Christiane; Øvergård, Aina-Cathrine; Nilsen, Frank et al. (2015). Molecular characterization and knock-down of salmon louse (Lepeophtheirus salmonis) prostaglandin E synthase. (ekstern lenke)
• Steigen, Andreas L; Karlsbakk, Egil; Plarre, Heidrun et al. (2014). A new intracellular bacterium, Candidatus Similichlamydia labri sp. nov. (Chlamydiaceae) producing epitheliocysts in ballan wrasse, Labrus bergylta (Pisces, Labridae). (ekstern lenke)
• Økland, Arnfinn Lodden; Nylund, Are; Øvergård, Aina-Cathrine et al. (2014). Genomic characterization and phylogenetic position of two new species in Rhabdoviridae infecting the parasitic copepod, salmon louse (Lepeophtheirus salmonis). (ekstern lenke)
• Øvergård, Aina-Cathrine; Patel, Sonal; Nøstbakken, Ole Jakob et al. (2013). Atlantic halibut (Hippoglossus hippoglossus L.) T-cell and cytokine response after vaccination and challenge with nodavirus. (ekstern lenke)
• Øvergård, Aina-Cathrine; Nepstad, Ina; Nerland, Audun H. et al. (2012). Characterisation and expression analysis of the Atlantic halibut (Hippoglossus hippoglosssus L.) cytokines: IL-1β, IL-6, IL-11, IL-12β and IFNγ. (ekstern lenke)
• Øvergård, Aina-Cathrine; Nerland, Audun Helge; Fiksdal, Ingrid Uglenes et al. (2012). Atlantic halibut experimentally infected with nodavirus shows increased levels of T-cell marker and IFN gamma transcripts. (ekstern lenke)
• Øvergård, Aina-Cathrine; Fiksdal, Ingrid Uglenes; Nerland, Audun H. et al. (2011). Expression of T-cell markers during Atlantic halibut (Hippoglossus hippoglossus L.) ontogenesis. (ekstern lenke)
• Øvergård, Aina-Cathrine; Nerland, Audun H.; Patel, Sonal (2010). Cloning, characterization, and expression pattern of Atlantic halibut (Hippoglossus hippoglossus L.) CD4-2, Lck, and ZAP-70. (ekstern lenke)
• Øvergård, Aina-Cathrine; Nerland, Audun H.; Patel, Sonal (2010). Evaluation of potential reference genes for real time RT-PCR studies in Atlantic halibut (Hippoglossus Hippoglossus L.); during development, in tissues of healthy and NNV-injected fish, and in anterior kidney leucocytes. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hordvik, Ivar; Nerland, Audun H. et al. (2009). Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes. (ekstern lenke)
• Patel, Sonal; Øvergård, Aina-Cathrine; Nerland, Audun H. (2009). A CD4 homologue in Atlantic halibut (Hippoglossus hippoglossus): Molecular cloning and characterisation. (ekstern lenke)
• Patel, Sonal; Øvergård, Aina-Cathrine; Nerland, Audun H. (2008). CD8 alpha and CD8 beta in Atlantic halibut, Hippoglossus hippoglossus: Cloning, characterization and gene expression during viral and bacterial infection. (ekstern lenke)

Sammendrag/abstract

• Midtbø, Helena Marie Doherty; Haugland, Gyri Teien; Borchel, Andreas et al. (2023). LsLGP3 from Salmon Louse (Lepeophtheirus salmonis) Causes Cell Death in Atlantic salmon (Salmo salar) Leukocytes. (ekstern lenke)

Vitenskapelig foredrag

• Bjune, Anne Elisabeth; Bratbak, Gunnar; Eliassen, Sigrunn et al. (2023). Omlegging fra tradisjonelle forelesninger til studentaktiv læring – eksempel fra et grunnemne i biolog. (ekstern lenke)
• Midtbø, Helena Marie Doherty; Haugland, Gyri Teien; Øvergård, Aina-Cathrine (2022). Does Salmon louse Have an Immune Dampening Effect on Atlantic Salmon? . (ekstern lenke)
• Øvergård, Aina-Cathrine (2020). Grunnleggende lusebiologi – hva vet vi, og hva skal studeres. . (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Grotmol, Sindre et al. (2019). Lusespytt modulerer laksens immunrespons. (ekstern lenke)
• Våge, Selina; Eilertsen, Mariann; Øvergård, Aina-Cathrine et al. (2019). Learning outcomes at master level in biology. Current expectations and guidelines for the future. (ekstern lenke)
• Øvergård, Aina-Cathrine; Nilsen, Frank; Nuñez-Ortiz, Noelia et al. (2019). THE SALMON LOUSE (LEPEOPHTHEIRUS SALMONIS) SALIVARY GLAND SECRETES IMMUNE REGULATORY PROTEINS. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Grotmol, Sindre et al. (2018). DO Lepeophtheirus salmonis RHABDOVIRUSES (LsRVs) DAMPEN THE LOCAL SKIN INFLAMMATORY RESPONSE IN ATLANTIC SALMON Salmo salar?. (ekstern lenke)
• Poley, Jordan; Braden, Laura; Michaud, Dylan et al. (2018). Excretory and Secretory Factors of the Salmon Louse: Genomic Characterization, Effects on Feeding, and Impacts on Host Immunity. (ekstern lenke)
• Dalvin, Sussie; VG Jørgensen, Louise; Kania, Per W. et al. (2018). MORPHOLOGICAL AND IMMUNOLOGICAL CHANGES IN RAINBOW TROUT SKIN IN RESPONSE TO SALMON LOUSE INFECTION. (ekstern lenke)
• Dalvin, Sussie; Øvergård, Aina-Cathrine; Eichner, Christiane et al. (2017). Do prostaglandins produced by lepeophtheirus salmonis affect the interaction between the parasite and the fish?. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Harasimczuk, Ewa et al. (2017). Exocrine glands of Lepeophtheirus salmonis and secretion of possible immune regulatory proteins.. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hamre, Lars Are; Harasimczuk, Ewa et al. (2016). Distribution and Development of salmon louse Lepeophtheirus salmonis exocrine glands. (ekstern lenke)
• Eichner, Christiane; Øvergård, Aina-Cathrine; Nilsen, Frank et al. (2014). Characterization and knock-down of a putative prostaglandin e synthase found in Lepeophtheirus salmonis. (ekstern lenke)
• Nerland, Audun H.; Øvergård, Aina-Cathrine; Patel, Sonal (2010). Molecular approaches for development of vaccines against intracellular fish pathogens. (ekstern lenke)
• Patel, Sonal; Øvergård, Aina-Cathrine; Sørhus, Elin et al. (2009). B and T cell markers during Atlantic halibut (Hippoglossus hippoglossus) ontogenesis. (ekstern lenke)
• Øvergård, Aina-Cathrine; Nerland, Audun H.; Patel, Sonal (2009). Relativ uttrykning av T-celle markører i tidlige livsstadier hos Atlantisk kveite (Hippoglossus hippoglossus). (ekstern lenke)

Mastergradsoppgave

• Henrikke, Oppedal; Bui, Samantha; Øvergård, Aina-Cathrine (2021). Refilling behaviour of Atlantic salmon (Salmo salar) with different air-dome heights. (ekstern lenke)

Populærvitenskapelig artikkel

• Øvergård, Aina-Cathrine; Hamre, Lars Are (2020). Skottelusen: en kilde til viktig kunnskap, men også en mulig fremtidig trussel?. (ekstern lenke)

Poster

• Øvergård, Aina-Cathrine; Hamre, Lars Are; Harasimczuk, Ewa et al. (2017). Eksokrine kjertler i lakselus (Lepeophtheirus salmonis). (ekstern lenke)
• Dondrup, Michael; Zhang, Wei; Zhou, Zhaoran et al. (2016). Licebase-a species focused resource for sea lice including an RNAi LIMS andtools for data analysis and genome annotation. (ekstern lenke)

Rapport

• Sandlund, Nina; Dalvin, Sussie Trine; Øvergård, Aina-Cathrine et al. (2014). Sekvensering av havet – fremtidens teknologi. (ekstern lenke)

Doktorgradsavhandling

• Øvergård, Aina-Cathrine (2012). T-cells and cytokines of Atlantic halibut (Hippoglossus hippoglossus L.) - Gene expression levels during ontogenesis, vaccination and experimental nodavirus infection. (ekstern lenke)

Vitenskapelig Kapittel/Artikkel/Konferanseartikkel

• Nerland, Audun H.; Øvergård, Aina-Cathrine; Patel, Sonal (2011). Viruses of Fish. (ekstern lenke)

Populærvitenskapelig kapittel/artikkel

• Patel, Sonal; Øvergård, Aina-Cathrine; Fiksdal, Ingrid Uglenes et al. (2011). Tidlig vaksinering – mot sin hensikt. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

SaliVax (https://www.fhf.no/prosjekter/prosjektbasen/901760/)

SaliFilaVax (https://www.fhf.no/prosjekter/prosjektbasen/901868/)