Odd André Karlsen
Stilling
Professor
Tilhørighet
Forskergrupper
Forskning
Min forskningsinteresse handler om å forstå de molekylære mekanismene og prosessene som ligger bak toksisiteten forårsaket av eksponering for miljøgifter, og hvordan dette forplanter seg videre oppover i biologiske nivåer og gir effekter på individ og populasjonsnivå. Forskningen min fokuserer hovedsaklig på marine organismer, og sentrale temaer er hormonforstyrrende stoffer, kjernereseptorer, biomarkører, bioassays, mikroplast, integrativ genomikk, "nye" miljøgifter, og blandingseffekter.
For tiden leder jeg Plastnettverket ved Universitetet i Bergen. Plastnettverket omfavner tverrfaglig forskning om plast i havet. Dette innebærer tilstedeværelse, spredning og effekter av plast og mikroplast, samt den samfunnsvitenskapelige, juridiske og medisinske forskningen omkring plastproblematikken.
Undervisning
Emneansvarlig for BIO216 Toksikologi (emneevaluering)
Veileder i BIO299 Prosjektoppgave i biologi/molekylærbiologi
Foreleser i BIO208 Miljøpåvirkning av oppdrett
Foreleser i BIO316 Utvalgte emner i miljøtoksikologi
Vitenskapelig koordinator for masterretningen Miljøtoksikologi ved institutt for biovitenskap.
Publikasjoner
Poster
- Ruivo, Raquel; Danneels, Bram; Oliveira, Diogo et al. (2024). Gene loss events shaped the chemical defensome in Cetacea. (ekstern lenke)
- Danneels, Bram; Ruivo, Raquel; Oliveira, Diogo et al. (2024). Gene set annotation and pseudogene prediction using reference genomes. (ekstern lenke)
- Strople, Leah Catherine; Vieweg, Ireen; Yadetie, Fekadu et al. (2022). Reproductive development in polar cod (Boreogadus saida) exposed to crude oil and food variability. (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja Rebecca; Giebichenstein, Julia et al. (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. (ekstern lenke)
- Goksøyr, Anders; Goksøyr, Siri Øfsthus; Yadetie, Fekadu et al. (2021). Development of a battery of Atlantic cod receptor-based reporter bioassays for assessing environmental toxicity of sediments and chemicals. (ekstern lenke)
- Johansen, Christine T.; Goksøyr, Siri Øfsthus; Yadetie, Fekadu et al. (2019). In vitro assessment of estrogenic effects of bisphenols on Atlantic cod (Gadus morhua). (ekstern lenke)
- Johansen, Christine T.; Goksøyr, Siri Øfsthus; Yadetie, Fekadu et al. (2019). Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Ueland, Elisabeth; Lille-Langøy, Roger et al. (2019). Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua). (ekstern lenke)
- Dale, Karina; Müller, Mette Helen Bjørge; Tairova, Zhanna et al. (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) . (ekstern lenke)
- Zhang, Xiaokang; Eide, Marta; Karlsen, Odd Andre et al. (2019). THE CHEMICAL DEFENSOME OF ATLANTIC COD (GADUS MORHUA): HOW DOES IT DIFFER FROM DEFENSOME NETWORKS IN OTHER TELEOST SPECIES?. (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd Andre et al. (2019). Chemical warfare in the aquatic environment - The chemical defensome networks of model fish species. (ekstern lenke)
- Goksøyr, Anders; Alendal, Guttorm; Aranguren-Abadía, Libe et al. (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR. (ekstern lenke)
- Karlsen, Odd Andre; Madsen, Alexander Klevedal; Sørensen, Lisbet et al. (2019). Assessment of produced water toxicity using in vitro tools developed from Atlantic cod (Gadus morhua). (ekstern lenke)
- Hansen, Bjørn Henrik; Sørensen, Lisbet; Sørhus, Elin et al. (2018). PW-Exposed: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Söderström, Sofie; Ueland, Elisabeth et al. (2018). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua). (ekstern lenke)
- Sôderstrôm, Sofie; Goksøyr, Anders; Karlsen, Odd Andre (2018). Effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors. (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd Andre et al. (2018). MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human. (ekstern lenke)
- Aranguren, Libe; Madsen, Alexander K; Iden, Pernille et al. (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua). (ekstern lenke)
- Aranguren, Libe; Madsen, Alexander K; Iden, Pernille et al. (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua). (ekstern lenke)
- Goksøyr, Siri Øfsthus; Söderström, Sofie; Ueland, Elisabeth et al. (2017). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua). (ekstern lenke)
- Dale, Karina; Karlsen, Odd Andre; Yadetie, Fekadu et al. (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway . (ekstern lenke)
- Kolås, Mari Forshaug; Aranguren, Libe; Yadetie, Fekadu et al. (2017). Using precision cut liver slices (PCLS) for studying effects of environmental contaminants on the Atlantic cod (Gadus morhua) lipid metabolism. (ekstern lenke)
- Dale, Karina; Karlsen, Odd Andre; Yadetie, Fekadu et al. (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway . (ekstern lenke)
- Aranguren, Libe; Madsen, Alexander K; Iden, Pernille et al. (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua). (ekstern lenke)
- Goksøyr, Anders; Celander, Malin; Alendal, Guttorm et al. (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua). (ekstern lenke)
- Goksøyr, Siri Øfsthus; Yadetie, Fekadu; Eide, Marta et al. (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Yadetie, Fekadu; Eide, Marta et al. (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Goksøyr, Anders; Karlsen, Odd Andre et al. (2017). dCod 1.0 decoding the systems toxicology of Atlantic cod. (ekstern lenke)
- Steinkopf, Oline Marie; Goksøyr, Siri Øfsthus; Lille-Langøy, Roger et al. (2017). Studying estrogenic effects of environmental pollutants by using the Atlantic cod (Gadus morhua) estrogen receptor α and a reporter gene assay. (ekstern lenke)
- Dale, Karina; Karlsen, Odd Andre; Yadetie, Fekadu et al. (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway . (ekstern lenke)
- Söderström, Sofie; Lille-Langøy, Roger; Goksøyr, Anders et al. (2017). Peroxisome proliferator-activated receptors (PPARs) as tools for studying effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism. (ekstern lenke)
- Söderstrøm, Sofie; Lille-Langøy, Roger; Goksøyr, Anders et al. (2016). Peroxisome proliferator-activated receptors (PPARs) as tools to study effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism. (ekstern lenke)
- Pernille, Iden; Yadetie, Fekadu; Eide, Marta et al. (2016). Effektar på lipidmetabolismen til atlanterhavstorsk (Gadus morhua) etter eksponering mot enkeltsambindingar og blandingar av miljøgiftar. (ekstern lenke)
- Yadetie, Fekadu; Karlsen, Odd Andre; Eide, Marta et al. (2016). Systems Toxicology Studies to Investigate Mechanisms of Toxicity of Environmental Chemicals Using Atlantic cod (Gadus morhua) as a Model Organism.. (ekstern lenke)
- Yadetie, Fekadu; Eide, Marta; Oveland, Eystein et al. (2016). Integrated analysis of transcriptome and proteome reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with the persistent organic pollutant PCB 153 . (ekstern lenke)
- Aranguren, Libe; Madsen, Alexander K; Iden, Pernille et al. (2016). Using precision-cut liver slices (PCLS) and luciferase reporter gene assay to characterize the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua). (ekstern lenke)
- Brattås, Marianne; Karlsen, Odd Andre; Goksøyr, Anders et al. (2014). Alterations in the hepatic proteome of polar cod (Boreogadus saida) after dietary exposure to benzo(a)pyrene . (ekstern lenke)
- Eide, Marta; Karlsen, Odd Andre; Olsvik, Pål Asgeir et al. (2012). Integrative environmental genomics of Atlantic cod (Gadus morhua): exposure of cod liver slices to environmental contaminants. (ekstern lenke)
- Hole, Kristine; Evjenth, Rune Henrik; Karlsen, Odd Andre et al. (2010). Human Naa50p (Nat5/San) Displays Both Protein Na-and Ne-Acetyltransferase activity. (ekstern lenke)
- Karlsen, Odd Andre; Fjellbirkeland, Anne; Angelskår, S. M. et al. (2004). Copper-regulation of some surface-exposed and secreted proteins of the methane-oxidizing bacterium Methylococcus capsulatus (Bath). (ekstern lenke)
- Bruseth, Live J.; Straume, Daniel; Karlsen, Odd Andre et al. (2004). An introduction to copper homeostasis in Methylococcus capsulatus. (ekstern lenke)
- Bruseth, Live J.; Straume, Daniel; Larsen, Øivind et al. (2004). Copper homeostasis in Methylococcus capsulatus. (ekstern lenke)
- Karlsen, Odd Andre; Fjellbirkeland, Anne; Angelskår, S. M. et al. (2004). Surface proteins of M. capsulatus (Bath) possibly involved in copper uptake. (ekstern lenke)
- Karlsen, Odd Andre; Berven, Frode; Larsen, Øivind et al. (2003). Differential expression in sMMO and pMMO producing cells of Methylococcus capsulatus (Bath). (ekstern lenke)
- Karlsen, Odd Andre; Berven, Frode; Larsen, Øivind et al. (2003). Identification of the ORF upstream of MopE in Methylococcus capsulatus. (ekstern lenke)
- Fjellbirkeland, Anne; Karlsen, Odd Andre; Berven, Frode et al. (2002). Characterization of copper-repressible extracellular protein of Methylococcus capsulatus (Bath). (ekstern lenke)
- Berven, Frode; Karlsen, Odd Andre; Jensen, Harald B (2002). Initial proteome studies on Methylococcus capsulatus (Bath). (ekstern lenke)
Vitenskapelig foredrag
- Oliveira, Diogo; Danneels, Bram; Karlsen, Odd André et al. (2024). Massive gene loss and the making of xenobiotic-induced responses in Cetacea. (ekstern lenke)
- Søderstrøm, Sofie Karin; Einevoll Fimreite, Gunvor; Mukundan, Anya Greta et al. (2024). Decoding marine mammal toxicology. (ekstern lenke)
- Søderstrøm, Sofie Karin; Blévin, Pierre; Rikardsen, Audun Håvard et al. (2024). The Marma-detox project ( 2023-2027) “Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches . (ekstern lenke)
- Brun, Nadja R; Eide, Marta; Goksøyr, Siri Øfsthus et al. (2023). Toxicogenomics using precision-cut liver slice culture in fish. (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja Rebecca; Müller, Mette Helen Bjørge et al. (2023). Toxicogenomics using precision-cut liver slice culture in fish . (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja Rebecca; Vieweg, Ireen et al. (2021). Genomic responses to pollutants in Arctic fish and copepod species. (ekstern lenke)
- Strople, Leah Catherine; Vieweg, Ireen; Yadetie, Fekadu et al. (2020). Polar cod and Goliat: How an oil spill may affect polar cod reproduction. (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja R; Vieweg, Ireen et al. (2020). ANTIESTROGENIC EFFECTS OF BENZO[a]PYRENE REVEALED BY TRANSCRIPTOME ANALYSIS IN POLAR COD LIVER SLICE CULTURE. (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja; Vieweg, Ireen et al. (2020). Adapting a liver slice culture method for ex vivo toxicological studies in arctic and sub-arctic fish species during sampling cruises. (ekstern lenke)
- Strople, Leah; Vieweg, Ireen; Yadetie, Fekadu et al. (2020). Polar cod and Goliat: How an oil spill may affect polar cod reproduction. (ekstern lenke)
- Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu et al. (2020). A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua). (ekstern lenke)
- Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc et al. (2019). Agricultural pesticides in aquafeeds might harm wild fish feeding on leftover pellets near fish farms.. (ekstern lenke)
- Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc et al. (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Conference talk. (ekstern lenke)
- Yadetie, Fekadu; Zhang, Xiaokang; Hanna, Eileen Marie et al. (2019). EFFECTS OF SELECTED ENVIRONMENTAL ESTROGENS ON EXPRESSION OF FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY GENES IN THE LIVER OF ATLANTIC COD (GADUS MORHUA) IN VIVO AND EX VIVO. (ekstern lenke)
- Dale, Karina; Müller, Mette Helen Bjørge; Tairova, Zhanna et al. (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. (ekstern lenke)
- Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge et al. (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. (ekstern lenke)
- Yadetie, Fekadu; Zhang, Xiaokang; Hanna, Eileen Marie et al. (2019). Toxicogenomic responses in Atlantic cod (Gadus morhua) after treatment with selected environmental contaminants in vivo and ex vivo. (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd Andre et al. (2019). The chemical defensome of Atlantic cod (Gadus morhua). (ekstern lenke)
- Goksøyr, Siri Øfsthus; Johansen, Christine T.; Viken, Kristianne Hjort et al. (2019). In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua). (ekstern lenke)
- Goksøyr, Anders; Alendal, Guttorm; Aranguren-Abadía, Libe et al. (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Johansen, Christine T.; Viken, Kristianne Hjort et al. (2019). Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices. (ekstern lenke)
- Yadetie, Fekadu; Zhang, Xiaokang; Hanna, Eileen Marie et al. (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. (ekstern lenke)
- Dale, Karina; Karlsen, Odd Andre; Yadetie, Fekadu et al. (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway . (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd Andre et al. (2018). Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans. (ekstern lenke)
- Zhang, Xiaokang; Eide, Marta; Karlsen, Odd Andre et al. (2018). Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human. (ekstern lenke)
- Goksøyr, Anders; Alendal, Guttorm; Aranguren Abadía, Libe et al. (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA). (ekstern lenke)
- Dale, Karina; Karlsen, Odd Andre; Yadetie, Fekadu et al. (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway . (ekstern lenke)
- Aranguren Abadía, Libe; Lille-Langøy, Roger; Karchner, Sibel I. et al. (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua). (ekstern lenke)
- Karlsen, Odd Andre; Sôderstrôm, Sofie; Goksøyr, Siri Øfsthus et al. (2018). The nuclear receptor complement of Atlantic cod (Gadus morhua) as potential targets for endocrine disrupting compounds. (ekstern lenke)
- Sôderstrôm, Sofie; Goksøyr, Anders; Karlsen, Odd Andre (2018). Agonistic and antagonistic effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors. (ekstern lenke)
- Aranguren Abadía, Libe; Lille-Langøy, Roger; Karchner, Sibel I. et al. (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua). (ekstern lenke)
- Yadetie, Fekadu; Zhang, Xiaokang; Hanna, Eileen Marie et al. (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. (ekstern lenke)
- Aranguren-Abadía, Libe; Lille-Langøy, Roger; Karchner, Sibel I. et al. (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.. (ekstern lenke)
- Aranguren Abadía, Libe; Lille-Langøy, Roger; Karchner, Sibel I. et al. (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.. (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd Andre et al. (2018). Modelling the chemical defensome network - a dynamic visualisation of the involved genes and pathways in two fish species and humans . (ekstern lenke)
- Goksøyr, Siri Øfsthus; Grøsvik, Bjørn Einar; Pampanin, Daniela Maria et al. (2018). Establishing a cellfree method for xenobiotic detection using ligand activated receptors from the Atlantic cod, Gadus morhua. (ekstern lenke)
- Yadetie, Fekadu; Eide, Marta; Söderström, Sofie et al. (2017). PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT. (ekstern lenke)
- Aranguren, Libe; Madsen, Alexander K; Iden, Pernille et al. (2017). CHARACTERIZATION OF THE ARYL HYDROCARBON RECEPTORS AHR1B AND AHR2 IN ATLANTIC COD (GADUS MORHUA). (ekstern lenke)
- Dale, Karina; Goksøyr, Anders; Karlsen, Odd Andre et al. (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway . (ekstern lenke)
- Yadetie, Fekadu; Eide, Marta; Oveland, Eystein et al. (2017). Integrative transcriptome and proteome analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. (ekstern lenke)
- Karlsen, Odd Andre; Yadetie, Fekadu; Aranguren, Libe et al. (2016). Toxicogenomics as a tool for understanding responses to pollutants in organisms: Using Atlantic cod (Gadus morhua) and a systems biology approach to environmental toxicology. (ekstern lenke)
- Karlsen, Odd Andre; Yadetie, Fekadu; Eide, Marta et al. (2016). Integrative -omics analyses reveal perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) exposed to the persistent organic pollutant PCB 153. (ekstern lenke)
- Eide, Marta; Puntervoll, Pål; Lille-Langøy, Roger et al. (2016). Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor. (ekstern lenke)
- Brattås, Marianne; Karlsen, Odd Andre; Goksøyr, Anders et al. (2014). ALTERATIONS IN THE HEPATIC PROTEOME OF POLAR COD (BOREOGADUS SAIDA) AFTER DIETARY EXPOSURE TO BENZO[A]PYRENE. (ekstern lenke)
- Yadetie, Fekadu; Karlsen, Odd Andre; Berg, Karin et al. (2011). Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.. (ekstern lenke)
- Karlsen, Odd Andre; Berven, Frode; Bruseth, Live Janicke et al. (2003). The expression of the surface associated MopE protein of Methylococcus capsulatus (Bath) is regulated by the concentration of copper in the growth medium. (ekstern lenke)
- Berven, Frode; Karlsen, Odd Andre; Fjellbirkeland, Anne et al. (2003). Proteome studies on the methanotrophic bacterium Methylococcus capsulatus (Bath). (ekstern lenke)
- Berven, Frode; Karlsen, Odd Andre; Murrell, Colin et al. (2003). Multiple polypeptide forms observed in twodimensional gels of Methylococcus capsulatus (Bath)polypeptides are generated during the separation procedure. (ekstern lenke)
- Berven, Frode; Karlsen, Odd Andre; Jensen, Harald B (2002). Initial proteome studies of Methylococcus capsulatus (Bath). (ekstern lenke)
Faglig foredrag
- Danneels, Bram; Goksøyr, Anders; Jonassen, Inge et al. (2024). Gene loss in the chemical defensome of marine mammals. (ekstern lenke)
- zamani, sara; Yadetie, Fekadu; Pampanin, Daniela Maria et al. (2023). Dexamethasone-associated metabolic effects in Atlantic cod. (ekstern lenke)
- Goksøyr, Anders; Eide, Marta; Brun, Nadja Rebecca et al. (2022). Complex mixture and omics responses in Atlantic cod: a time- and dose-response study. (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd Andre et al. (2019). Chemical warfare in the marine environment. (ekstern lenke)
- Aranguren Abadía, Libe; Lille-Langøy, Roger; Karchner, Sibel I. et al. (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a. (ekstern lenke)
Vitenskapelig artikkel
- Goksøyr, Siri Øfsthus; Yadetie, Fekadu; Johansen, Christine et al. (2024). Interaction of Bisphenol A and Its Analogs with Estrogen and Androgen Receptor from Atlantic Cod (Gadus morhua). (ekstern lenke)
- Eze, Chukwuebuka ThankGod; Otitoloju, Adebayo Akeem; Eze, Obianuju Oluchukwu et al. (2023). West African e-waste-soil assessed with a battery of cell-based bioassays. (ekstern lenke)
- Bogevik, André Sture; Ytteborg, Elisabeth; Madsen, Alexander Klevedal et al. (2023). PCB-126 spiked to polyethylene microplastic ingested by juvenile Atlantic cod (Gadus morhua) accumulates in liver and muscle tissues. (ekstern lenke)
- Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu et al. (2023). Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod. (ekstern lenke)
- Olsvik, Pål Asgeir; Meier, Sonnich; Zhang, Xiaokang et al. (2023). Environmentally realistic concentrations of chlorinated, brominated, and fluorinated persistent organic pollutants induce the unfolded protein response as a shared stress pathway in the liver of Atlantic cod (Gadus morhua). (ekstern lenke)
- Strople, Leah C.; Vieweg, Ireen; Yadetie, Fekadu et al. (2023). Spawning time in adult polar cod (Boreogadus saida) altered by crude oil exposure, independent of food availability. (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja Rebecca; Giebichenstein, Julia et al. (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. (ekstern lenke)
- Söderström, Sofie Karin; Lille-Langøy, Roger; Yadetie, Fekadu et al. (2022). Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). (ekstern lenke)
- Dale, Karina; Yadetie, Fekadu; Horvli, Torill et al. (2022). Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). (ekstern lenke)
- Aranguren Abadía, Libe; Yadetie, Fekadu; Donald, Carey et al. (2022). Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). (ekstern lenke)
- Yadetie, Fekadu; Brun, Nadja Rebecca; Vieweg, Ireen et al. (2021). Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. (ekstern lenke)
- Eide, Marta; Zhang, Xiaokang; Karlsen, Odd André et al. (2021). The chemical defensome of five model teleost fish. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Sørensen, Helene; Grøsvik, Bjørn Einar et al. (2021). Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. (ekstern lenke)
- Lille-Langøy, Roger; Jørgensen, Kåre Bredeli; Goksøyr, Anders et al. (2021). Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. (ekstern lenke)
- Strobel, Anneli; Lille-Langøy, Roger; Segner, Helmut et al. (2021). Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. (ekstern lenke)
- Goksøyr, Siri Øfsthus; Goldstone, Jed; Lille-Langøy, Roger et al. (2021). Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. (ekstern lenke)
- Aranguren Abadía, Libe; Donald, Carey; Eilertsen, Mariann et al. (2020). Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua). (ekstern lenke)
- Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge et al. (2020). Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua). (ekstern lenke)
- Aranguren-Abadía, Libe; Lille-Langøy, Roger; Madsen, Alexander Klevedal et al. (2020). Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. (ekstern lenke)
- Bilal, Sumaira; Lie, Kai Kristoffer; Dalum, Alf Seljenes et al. (2019). Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. (ekstern lenke)
- Dale, Karina; Müller, Mette Bjørge; Tairova, Zhanna et al. (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. (ekstern lenke)
- Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc et al. (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. (ekstern lenke)
- Khan, Essa Ahsan; Bertotto, Luisa B.; Dale, Karina et al. (2019). Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. (ekstern lenke)
- Ahmed , Kareem Eldin Mohammed ; Frøysa, Håvard G; Karlsen, Odd Andre et al. (2018). Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. (ekstern lenke)
- Kareem Eldin, Mohammed Adhmed Abdel Ghafar; Frøysa, Håvard G; Karlsen, Odd Andre et al. (2018). LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. (ekstern lenke)
- Eide, Marta; Rydbeck, Halfdan; Tørresen, Ole K. et al. (2018). Independent losses of a xenobiotic receptor across teleost evolution. (ekstern lenke)
- Lille-Langøy, Roger; Karlsen, Odd Andre; Myklebust, Line Merethe et al. (2018). Sequence variations in pxr (nr1i2) from Zebrafish (Danio rerio) strains affect nuclear receptor function. (ekstern lenke)
- Yadetie, Fekadu; Zhang, Xiaokang; Hanna, Eileen Marie et al. (2018). RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. (ekstern lenke)
- Blanco, Maria; Perez-Albaladejo, Elisabet; Pina, Benjamin et al. (2018). Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. (ekstern lenke)
- Yadetie, Fekadu; Oveland, Eystein; Døskeland, Anne Marie Simonne et al. (2017). Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. (ekstern lenke)
- Bilal, Sumaira; Lie, Kai Kristoffer; Karlsen, Odd Andre et al. (2016). Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). (ekstern lenke)
- Larsen, Øivind; Karlsen, Odd Andre (2016). Transcriptomic profiling of Methylococcus capsulatus (Bath)during growth with two different methane monooxygenases. (ekstern lenke)
- Yadetie, Fekadu; Bjørneklett, Silje; Garberg, Hilde Kristin et al. (2016). Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. (ekstern lenke)
- Perez-Albaladejo, Elisabet; Rizzi, Juliane; Fernandes, Denise et al. (2016). Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays. (ekstern lenke)
- Eide, Marta; Karlsen, Odd Andre; Kryvi, Harald et al. (2014). Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vitro system for studying the effects of environmental contaminants. (ekstern lenke)
- Yadetie, Fekadu; Karlsen, Odd Andre; Eide, Marta et al. (2014). Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism. (ekstern lenke)
- Johnson, Kenneth; Ve, Thomas; Larsen, Øivind et al. (2014). CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. (ekstern lenke)
- Karlsen, Odd Andre; Sheehan, David; Goksøyr, Anders (2014). Alterations in the atlantic COD (Gadus morhua) hepatic thiol-proteome after methylmercury exposure. (ekstern lenke)
- Yadetie, Fekadu; Karlsen, Odd Andre; Lanzén, Anders et al. (2013). Global transcriptome analysis of Atlantic cod (Gadus morhua) liver after in vivo methylmercury exposure suggests effects on energy metabolism pathways. (ekstern lenke)
- Ve, Thomas; Mathisen, Karina; Helland, Ronny et al. (2012). The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. (ekstern lenke)
- Karlsen, Odd Andre; Puntervoll, Pål; Goksøyr, Anders (2012). Mass spectrometric analyses of microsomal cytochrome P450 isozymes isolated from beta-naphthoflavone-treated Atlantic cod (Gadus morhua) liver reveal insights into the cod CYPome. (ekstern lenke)
- Yadetie, Fekadu; Butcher, Stephen; Førde, Hilde Elise Sundsøy et al. (2012). Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics. (ekstern lenke)
- Karlsen, Odd Andre; Bjørneklett, Silje; Berg, Karin et al. (2011). Integrative Environmental Genomics of Cod (Gadus morhua): The Proteomics Approach. (ekstern lenke)
- Karlsen, Odd Andre; Larsen, Øivind; Jensen, Harald B (2010). Identification of a bacterial di-haem cytochrome c peroxidase from Methylomicrobium album BG8. (ekstern lenke)
- Evjenth, Rune Henrik; Hole, Kristine; Karlsen, Odd Andre et al. (2009). Human Naa50p (Nat5/San) Displays Both Protein N-alpha- and N-epsilon-Acetyltransferase Activity. (ekstern lenke)
- Karlsen, Odd Andre; Lillehaug, Johan; Jensen, Harald B (2008). The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper. (ekstern lenke)
- Helland, Ronny; Fjellbirkeland, Anne; Karlsen, Odd-Arne et al. (2008). An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. (ekstern lenke)
- Berven, Frode; Karlsen, Odd Andre; Straume, Anne Hege et al. (2006). Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. (ekstern lenke)
- Karlsen, Odd Andre; Ramsevik, Linda; Bruseth, Live J. et al. (2005). Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). (ekstern lenke)
- Karlsen, Odd Andre; Kindingstad, Louise; Angelskår, Solveig Mjelstad et al. (2005). Identification of a copper-repressible cytochrome c peroxidase of Methylococcus capsulatus (Bath); a member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins. (ekstern lenke)
- Markine-Goriaynoff, Nicolas; Gillet, Laurent; Karlsen, Odd Andre et al. (2004). The core 2 ß-1,6-N-acetylglucosaminyltransferase-M encoded by bovine herpesvirus 4 is not essential for virus replication despite contributing to post-translational modifications of structural proteins. (ekstern lenke)
- Berven, Frode; Karlsen, Odd Andre; Murrell, Colin et al. (2003). Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. (ekstern lenke)
- Karlsen, Odd Andre; Berven, Frode; Stafford, Grasham et al. (2003). The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. (ekstern lenke)
Doktorgradsavhandling
- Bilal, Sumaira; Hordvik, Ivar; Karlsen, Odd Andre (2019). Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta). (ekstern lenke)
- Karlsen, Odd Andre; Jensen, Harald B; Lillehaug, Johan (2005). Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath). (ekstern lenke)
Sammendrag/abstract
- Karlsen, Odd Andre; Yadetie, Fekadu; Eide, Marta et al. (2012). Integrative environmental genomics of cod (Gadus morhua) reveal the mechanisms underlying MeHg- and PCB153 induced toxicity. (ekstern lenke)
- Hole, Kristine; Karlsen, Odd Andre; Ziegler, Mathias et al. (2010). The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. (ekstern lenke)
- Evjenth, Rune Henrik; Hole, Kristine; Karlsen, Odd Andre et al. (2010). Human Naa50p (Nat5/San) displays both protein N-alpha- and N-epsilon-Acetyltransferase activity. (ekstern lenke)
- Karlsen, Odd Andre; Brattås, Marianne; Bjørneklett, Silje et al. (2010). iCod: Integrative environmental genomics of cod (Gadus morhua); the proteomics approach. (ekstern lenke)
Vitenskapelig oversiktsartikkel/review
- Karlsen, Odd Andre; Larsen, Øivind; Jensen, Harald B (2011). The copper responding surfaceome of Methylococccus capsulatus Bath. (ekstern lenke)
- Karlsen, Odd Andre; Berven, Frode; Jensen, Harald B et al. (2011). METHANOTROPH OUTER MEMBRANE PREPARATION. (ekstern lenke)
- Karlsen, Odd Andre; Berven, Frode; Bagstevold, June Iren Larsen| et al. (2011). Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. (ekstern lenke)
Hovedfagsoppgave
- Ramsevik, Linda; Lillehaug, Johan; Karlsen, Odd Andre et al. (2005). A study of McHr – a novel prokaryotic hemerythrin from Methylococcus capsulatus (Bath). (ekstern lenke)
- Angelskår, Solveig Mjelstad; Jensen, Harald B; Karlsen, Odd Andre et al. (2004). Studies of Methylococcus capsulatus (Bath): The surface associated protein SapE. (ekstern lenke)
- Karlsen, Odd Andre (2001). The proteome of Methylococcus capsulatus; An initial study by two-domentional gel electrophoresis. (ekstern lenke)
Prosjekter
2023-2027; Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches – Marma-detox (RCN), WP-leader
2023-2027; Reproductive toxicity and generational effects of a contaminant mixture in fish (ToxiGen)(RCN), Partner
2021-2025; Effects of antifouling copper coating in aquaculture – implications for fish health, performance and sustainability of production (CAPS)(RCN 325849), WP-leader
2020-2024; Distribution, fate and effects of microplastics in the appendicularian zooplankton Oikopleura dioica (UiB), PI
2021; dCod Pollution Sensing Kit (RCN 323092), Partner
2020-2023; Joint evaluation and mitigation of emerging contaminant risks (INTPART)(RCN (309476), WP-leader
2020-2022; Cellular responses to contaminant exposure in marine mammals from the Arctic (The FRAM-centre), Partner
2020; 8th Norwegian Environmental Toxicology Symposium (NETS) – Ocean Health in the Anthropocene (RCN 311098), PI
2018-2021; Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species (PW-EXPOSED)(RCN 280511), WP-leader
2016-2021; dCod 1.0 – decoding the systems toxicology of Atlantic cod (Gadus morhua)(RCN(248840), WP-leader
2015-2019; iCod 2.0 - integrative environmental genomics of Atlantic cod (Gadus morhua)(RCN 244564), PI
2015-2019; Network for improving research based higher education in basic and applied microbiology( EURASIA, PEA-LT-2016/10095), Partner
2015-2016; In vitro fish: New 3D models for nutritional and toxicological research RCN (244507), Partner
2009-2013; iCod – integrative envionmental genomics of cod (Gadus morhua)(RCN (92441) , PI
Utdanning
2005; Philosophiae Doctor (PhD) i molekylærbiologi. Tittel på avhandling: ”Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath)”. Molekylærbiologisk institutt, Universitetet i Bergen, Norge
2001; Candidatus scientiarum i molekylærbiologi. Tittel på hovedfagsoppgave: ”The proteome of Methylococcus capsulatus (Bath); An initial study by two-dimensional gel electrophoresis”. Molekylærbiologisk institutt, Universitetet i Bergen, Norge
1998; 35 vektall fra programmet "Høyskolekandidat i bioteknologi". Høyskolen i Hedmark, Hamar, Norge
Nylige forskningsartikler
Yadetie F, Brun NR, Giebichenstein J, Dmoch K, Hylland K, Borgå K, Karlsen OA, Goksøyr A. Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. Mar Genomics. 2022 Aug 12;65:100981. doi: 10.1016/j.margen.2022.100981.
Søderstrøm S, Lille-Langøy R, Yadetie F, Rauch M, Milinski A, Dejaegere A, Stote RH, Goksøyr A, Karlsen OA*. Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). Environ Int. 2022 May;163:107203. doi: 10.1016/j.envint.2022.107203.
Strobel A, Lille-Langøy R, Segner H, Burkhardt-Holm P, Goksøyr A, Karlsen OA. Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. Polar Biol. 2022;45(2):345-358. doi: 10.1007/s00300-021-02992-4.
Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A. Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). Sci Total Environ. 2022 Mar 25;814:152732. doi: 10.1016/j.scitotenv.2021.152732.
Lille-Langøy R, Jørgensen KB, Goksøyr A, Pampanin DM, Sydnes MO, Karlsen OA*. Substituted Two- to Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environ Sci Technol. 2021 Nov 16;55(22):15123-15135. doi: 10.1021/acs.est.1c02946.
Aranguren-Abadía L, Yadetie F, Donald CE, Sørhus E, Myklatun LE, Zhang X, Lie KK, Perrichon P, Nakken CL, Durif C, Shema S, Browman HI, Skiftesvik AB, Goksøyr A, Meier S, Karlsen OA*. Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). Sci Total Environ. 2022 Feb 10;807(Pt 1):150697. doi: 10.1016/j.scitotenv.2021.150697.
Goksøyr SØ, Goldstone J, Lille-Langøy R, Lock EJ, Olsvik PA, Goksøyr A, Karlsen OA*. Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. Aquat Toxicol. 2021 Jul 16;238:105914. doi: 10.1016/j.aquatox.2021.105914.
Goksøyr SØ, Sørensen H, Grøsvik BE, Pampanin DM, Goksøyr A, Karlsen OA*. Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. Environ Toxicol Pharmacol. 2021 Oct;87:103704. doi: 10.1016/j.etap.2021.103704.
Yadetie F, Brun NR, Vieweg I, Nahrgang J, Karlsen OA, Goksøyr A. Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. Toxicol In Vitro. 2021 Sep;75:105193. doi: 10.1016/j.tiv.2021.105193.
Eide M, Zhang X, Karlsen OA, Goldstone JV, Stegeman J, Jonassen I, Goksøyr A. The chemical defensome of five model teleost fish. Sci Rep. 2021 May 18;11(1):10546. doi: 10.1038/s41598-021-89948-0.