Clinical and epidemiological lung research.

Fields of particular interest: Obstructive lung disease (asthma and COPD), sleep related respiratory disorders, respiratory failure. 

 

Vitenskapelig artikkel

• Schleich, Florence; Larenas-Linnemann, Désirée; Altraja, Alan et al. (2025). Biomarker profile and disease burden associated with intermittent and long-term oral corticosteroid use in patients with severe asthma prior to biologic initiation in real-life (STAR). (ekstern lenke)
• Knudsen, Kristel Svalland; Husebø, Gunnar Reksten; Nielsen, Rune et al. (2025). Whole genome sequencing of the pulmonary microbiome in interstitial lung disease subtypes. (ekstern lenke)
• Lundetræ, Ragnhild S.; Lehmann, Sverre; Saxvig, Ingvild W. et al. (2025). Severity of obstructive sleep apnea is related to C-reactive protein levels: The influence of comorbidities and self-reported sleep duration. (ekstern lenke)
• Chen, Wenjia; Tran, Trung N.; Townend, John et al. (2025). Impact of biologics initiation on oral corticosteroid use in the International Severe Asthma Registry and the Optimum Patient Care Research Database: a pooled analysis of real-world data. (ekstern lenke)
• Opsahl, Ulrik Leidland; Berge, Morten Eirik; Lehmann, Sverre et al. (2025). Prediction of non-responders to oral appliance treatment of obstructive sleep apnea: a pilot study. (ekstern lenke)
• Johansson, Ann-Katrin; Omar, Ridwaan; Lehmann, Sverre et al. (2024). Oral Health Related Factors Predicting Severe COVID-19 Disease in Elderly Swedes. (ekstern lenke)
• Tangedal, Solveig; Nielsen, Rune; Aanerud, Marianne et al. (2024). Lower airway microbiota in COPD and healthy controls. (ekstern lenke)
• Opsahl, Ulrik Leidland; Berge, Morten Eirik; Lehmann, Sverre et al. (2024). Elastic Bands Improve Oral Appliance Treatment Effect on Obstructive Sleep Apnoea: A Randomised Crossover Trial. (ekstern lenke)
• Rogde, Åse Johnsen; Lehmann, Sverre; Halvorsen, Thomas et al. (2023). Prevalence and impact of exercise-induced laryngeal obstruction in asthma: a study protocol for a cross-sectional and longitudinal study. (ekstern lenke)
• Hansen, Susanne; Bülow, Anna von; Sandin, Patrik et al. (2023). Prevalence and management of severe asthma in the Nordic countries: findings from the NORDSTAR cohort. (ekstern lenke)
• Johansson, Gerd Ann-Katrin Janmyr; Omar, Ridwaan; Lehmann, Sverre et al. (2023). General and orofacial symptoms associated with acute and long COVID in 80- and 90-year-old Swedish COVID-19 survivors. (ekstern lenke)
• Chen, Wenjia; Tran, Trung N.; Sadatsafavi, Mohsen et al. (2023). Impact of Inititing Biologics in Patients With Severe Asthma on Long-term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry. (ekstern lenke)
• Pfeffer, Paul E.; Ali, Nasloon; Murray, Ruth et al. (2023). Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both. (ekstern lenke)
• Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune et al. (2022). The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease. (ekstern lenke)
• Chen, Wenjia; Sadatsafavi, Mohsen; Tran, Trung N. et al. (2022). Characterization of patients in the International Severe Asthma Registry with high steroid exposure who did or did not initiate biologic therapy. (ekstern lenke)
• Mjelle, Karin Elisabeth Sundt; Lehmann, Sverre; Saxvig, Ingvild W. et al. (2022). Association of Excessive Sleepiness, Pathological Fatigue, Depression, and Anxiety With Different Severity Levels of Obstructive Sleep Apnea. (ekstern lenke)
• Jonassen, Trygve Müller; Bjorvatn, Bjørn; Saxvig, Ingvild W. et al. (2022). Clinical information predicting severe obstructive sleep apnea: A cross-sectional study of patients waiting for sleep diagnostics. (ekstern lenke)
• Saeed, Sahrai; Romarheim, Synnøve Andrea; Mancia, Giuseppe et al. (2022). Characteristics of hypertension and arterial stiffness in obstructive sleep apnea: A Scandinavian experience from a prospective study of 6408 normotensive and hypertensive patients. (ekstern lenke)
• Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune et al. (2022). The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis. (ekstern lenke)
• Rogde, Åse Johnsen; Lehmann, Sverre; Clemm, Hege Synnøve Havstad et al. (2021). Inducible laryngeal obstruction in asthma. (ekstern lenke)
• Lundetræ, Ragnhild Stokke; Saxvig, Ingvild W.; Aurlien, Harald et al. (2021). Effect of Continuous Positive Airway Pressure on Symptoms and Prevalence of Insomnia in Patients With Obstructive Sleep Apnea: A Longitudinal Study. (ekstern lenke)
• Gjerde, Kjersti; Lehmann, Sverre; Bjorvatn, Bjørn et al. (2021). Partner perceptions are associated with objective sensor-measured adherence to oral appliance therapy in obstructive sleep apnea. (ekstern lenke)
• Leiten, Elise Orvedal; Eagan, Tomas Mikal; Martinsen, Einar Marius Hjellestad et al. (2020). Complications and discomfort after research bronchoscopy in the MicroCOPD study. (ekstern lenke)
• Lundetræ, Ragnhild Stokke; Saxvig, Ingvild W.; Lehmann, Sverre et al. (2020). Effect of continuous positive airway pressure on symptoms of anxiety and depression in patients with obstructive sleep apnea. (ekstern lenke)
• Opsahl, Ulrik Leidland; Berge, Morten Eirik; Lehmann, Sverre et al. (2020). Acoustic pharyngometry - A new method to facilitate oral appliance therapy. (ekstern lenke)
• Geale, Kirk; Darabi, Hater; Linh, Maria et al. (2020). NORDSTAR: paving the way for a new era in asthma research. (ekstern lenke)
• Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Leiten, Elise Orvedal et al. (2019). Motivation and response rates in bronchoscopy studies. (ekstern lenke)
• Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini et al. (2019). Health-related quality of life as predictor for mortality in patients treated with long-term mechanical ventilation. (ekstern lenke)
• Lehmann, Sverre; Ringbæk, Thomas; Løkke, Anders et al. (2019). A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: The DuoSleep study. (ekstern lenke)
• Opsahl, Ulrik Leidland; Johansson, Anders; Berge, Morten et al. (2018). Akustisk pharyngometri for bedre resultat av behandling med søvnapnéskinner. (ekstern lenke)
• Lundetræ, Ragnhild Stokke; Saxvig, Ingvild W.; Pallesen, Ståle et al. (2018). Prevalence of parasomnias in patients with obstructive sleep apnea. A registry-based cross-sectional study. (ekstern lenke)
• Tveit, Ragnhild L.; Lehmann, Sverre; Bjorvatn, Bjørn (2018). Prevalence of several somatic diseases depends on the presence and severity of obstructive sleep apnea. (ekstern lenke)
• Bjorvatn, Bjørn; Berge, Thomas; Lehmann, Sverre et al. (2018). No effect of a self-help book for insomnia in patients with obstructive sleep apnea and comorbid chronic insomnia – a randomized controlled trial.. (ekstern lenke)
• Bjorvatn, Bjørn; Rajakulendren, Narvini; Lehmann, Sverre et al. (2018). Increased severity of obstructive sleep apnea is associated with less anxiety and depression. (ekstern lenke)
• Aardal, Marit Elisabeth; Svendsen, Lene Løvendahl; Lehmann, Sverre et al. (2017). A pilot study of hot-wire, ultrasonic and wedge-bellows spirometer inter- and intra-variability. (ekstern lenke)
• Storesund, Anders Kjellevold; Johansson, Anders; Bjorvatn, Bjørn et al. (2017). Oral appliance treatment outcome can be predicted by continuous positive airway pressure in moderate to severe obstructive sleep apnea. (ekstern lenke)
• Herland, Trine; Eide, Geir Egil; Lehmann, Sverre et al. (2017). Lungefunksjon som risikofaktor for osteoporose og hoftebrudd. (ekstern lenke)
• Gjerde, Kjersti; Lehmann, Sverre; Naterstad, Ingvill Fjell et al. (2017). Reliability of an adherence monitoring sensor embedded in an oral appliance used for treatment of obstructive sleep apnea. (ekstern lenke)
• Grønseth, Rune; Drengenes, Christine; Wiker, Harald G et al. (2017). Protected sampling is preferable in bronchoscopic studies of the airway microbiome. (ekstern lenke)
• Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini et al. (2017). Factors associated with change in health-related quality of life among individuals treated with long-term mechanical ventilation, a 6-year follow-up study. (ekstern lenke)
• Herland, Trine; Apalset, Ellen M; Eide, Geir Egil et al. (2016). Airflow limitation as a risk factor for low bone mineral density and hip fracture.. (ekstern lenke)
• Herland, Trine; Apalset, Ellen M; Eide, Geir Egil et al. (2016). Airflow limitation as a risk factor for low bone mineral density and hip fracture. The Hordaland Health Study (HUSK) – 10 years follow-up of a general population. (ekstern lenke)
• Gabrielsen, Anne Marie; Omland, Torbjørn; Brokner, Mette et al. (2016). The effect of surgical and non-surgical weight loss on N-terminal pro-B-type natriuretic peptide and its relation to obstructive sleep apnea and pulmonary function. (ekstern lenke)
• Jonassen, Trygve Muller; Eagan, Tomas Mikal; Bjorvatn, Bjørn et al. (2016). Associations between obstructive lung disease and symptoms of obstructive sleep apnoea in a general population. (ekstern lenke)
• Bjorvatn, Bjørn; Lehmann, Sverre; Gulati, Shashi et al. (2015). Prevalence of excessive sleepiness is higher whereas insomnia is lower with greater severity of obstructive sleep apnea. (ekstern lenke)
• Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini et al. (2015). The Norwegian version of the Severe Respiratory Insufficiency Questionnaire. (ekstern lenke)
• Gjerde, Kjersti; Lehmann, Sverre; Berge, Morten Eirik et al. (2015). Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP. (ekstern lenke)
• Neukamm, Anke; Høiseth, Arne Didrik; Einvik, Gunnar et al. (2015). Rosuvastatin treatment in stable chronic obstructive pulmonary disease (RODEO): a randomized controlled trial. (ekstern lenke)
• Bjorvatn, Bjørn; Pallesen, Ståle; Grønli, Janne et al. (2014). Prevalence and correlates of insomnia and excessive sleepiness in adults with obstructive sleep apnea symptoms. (ekstern lenke)
• Rokstad, Ingrid Skinlo; Rokstad, Kirsten Skinlo; Holmen, Sissel et al. (2013). Electronic optional guidelines as a tool to improve the process of referring patients to specialized care: An intervention study. (ekstern lenke)
• Thomassen, Lars; Storstein, Anette; Jusufovic, Mirza et al. (2011). En kvinne med tilbakevendende arteriovenøse tromboser. (ekstern lenke)
• Hvidsten, Sophie Charlotte; Storesund, Lene; Wentzel-Larsen, Tore et al. (2010). Prevalence and predictors of undiagnosed chronic obstructive pulmonary disease in a Norwegian adult general population. (ekstern lenke)
• Lehmann, Sverre; Bakke, Per S.; Eide, Geir Egil et al. (2008). Clinical data discriminating between adults with positive and negative results on bronchodilator testing. (ekstern lenke)
• Gulsvik, Amund; Humerfelt, Sjur; Bakke, Per S. et al. (2008). Norwegian population surveys on respiratory health in adults: objectives, design, methods, quality controls and response rates. (ekstern lenke)
• Lehmann, Sverre; Bakke, Per; Eide, Geir Egil et al. (2007). Bronchodilator response to adrenergic (beta) (2)-agonists: Relationship to symptoms in an adult community. (ekstern lenke)
• Johannessen, Ane; Lehmann, Sverre; Omenaas, Ernst et al. (2006). Post-bronchodilator spirometry reference values in adults and implications for disease management. (ekstern lenke)
• Omenaas, Ernst; Dahl, Ronald; Bakke, Per et al. (2006). Nordic physician's management of asthma and chronic obstructive pulmonary disease. (ekstern lenke)
• Lehmann, Sverre; Bakke, Per; Eide, Geir Egil et al. (2006). Bronchodilator reversibility testing in an adult general population; the importance of smoking and anthropometrical variables on the response to a beta(2)-agonist. (ekstern lenke)
• Lehmann, Sverre; Vollset, Stein Emil; Nygaard, Harald et al. (2004). Factors determining performance of bronchodilator reversibility tests in middle-aged and elderly. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• Larenas-Linnemann, Désirée; Rhee, Chin Kook; Altraja, Alan et al. (2025). International Severe Asthma Registry (ISAR): 2017–2024 Status and Progress Update. (ekstern lenke)
• Saeed, Sahrai; Romarheim, Synnøve Andrea; Solheim, Eivind et al. (2022). Cardiovascular remodeling in obstructive sleep apnea: focus on arterial stiffness, left ventricular geometry and atrial fibrillation. (ekstern lenke)
• Porsbjerg, Celeste; Ulrik, Charlotte; Skjold, Tina et al. (2018). Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults. (ekstern lenke)

Leserinnlegg

• Chen, Wenjia; Tran, Trung N.; Sadatsafavi, Mohsen et al. (2024). Reply to “Exploring the long-term effects of biologic initiation in severe asthma: Insights from the International Severe Asthma Registry”. (ekstern lenke)
• Berge, Morten Eirik; Johansson, Anders; Bjorvatn, Bjørn et al. (2014). Oral appliance for sleep apnea. (ekstern lenke)
• Johannessen, Ane; Lehmann, Sverre; Omenaas, Ernst et al. (2007). Defining the lower limit of normal for FEV1/FVC - From the authors. (ekstern lenke)
• Lehmann, Sverre; Grebstad, J; Fondenes, O et al. (2005). Behandling av obstruktiv søvnapné. (ekstern lenke)

Intervju

• Lofthus, Elisabeth; Johansson, Anders; Lehmann, Sverre (2023). Søvnapnè: Virker umiddelbart. (ekstern lenke)

Poster

• Hansen, Susanne; Bülow, Anna von; Sandin, Patrik et al. (2022). The prevalence of severe asthma, use of oral corticosteroid and management strategies in the Nordic countries: results from the pan-Nordic NORDSTAR cohort. (ekstern lenke)
• Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini et al. (2017). Health related quality of life in patients treated with long-term mechanical ventilation. (ekstern lenke)
• Johannessen, Ane; Lehmann, Sverre; Omenaas, Ernst et al. (2005). Strategy for selecting a spirometric reference population. (ekstern lenke)

Kronikk

• Lehmann, Sverre; Skrede, Steinar; Knudsen, Kristel Svalland et al. (2022). Hva skjer med meg hvis jeg legges inn med covid-19 på Haukeland?. (ekstern lenke)
• Skrede, Steinar; Lehmann, Sverre; Mosevoll, Knut Anders et al. (2022). Satsning på overvåkingsmedisin gjør oss bedre rustet. (ekstern lenke)

Fagartikkel

• Aarli, Bernt Bøgvald; Lehmann, Sverre (2022). Alvorlig astma. (ekstern lenke)
• Johansson, Anders; Gjerde, Kjersti; Lehmann, Sverre et al. (2014). Skinnebehandling mot søvnapnè. (ekstern lenke)

Populærvitenskapelig artikkel

• Johansson, Anders; Bjorvatn, Bjørn; Saxegaard, Erik et al. (2018). Stor interesse for odontologisk søvnmedisin og søvnapné i Norge. (ekstern lenke)

Faglig foredrag

• Bjorvatn, Bjørn; Lehmann, Sverre; Johansson, Anders (2014). Søvnforstyrrelser. (ekstern lenke)

Errata

• Berge, Morten Eirik; Johansson, Anders; Gulati, Shashi et al. (2014). Skinnebehandling mot søvapne. (ekstern lenke)

Vitenskapelig foredrag

• Neukamm, Anke; Høiseth, Arne Didrik; Einvik, Gunnar et al. (2014). Effect Of Rosuvastatin Treatment In Stable COPD (RODEO). (ekstern lenke)

Doktorgradsavhandling

• Lehmann, Sverre (2008). Adrenergic bronchodilator test in community. Applicability and relationship to anthropometrical variables, smoking, respiratory symptoms, and lung function. (ekstern lenke)

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