Forskning
Diabetes, fedme og ernæring
Hormoner, diagnostikk og brystkreft
Hormonlaboratoriets forskningsgruppe http://www.uib.no/en/rg/hormonelaboratory
Mohn Nutrition Research Laboratory www.uib.no/mohn-elab
Undervisning
Hormonsykdommer og medisinsk biokjemi
Publikasjoner
Vitenskapelig artikkel
- Achilleas Fardellas; Emelie Barreby; Madara Brice et al. (2026). ADAR1 Controls Macrophage Scavenging and Lipid‐Buffering Programs in Metabolic Tissues. (ekstern lenke)
- Marianne Bråtveit; Pouda Panahandeh Strømland; Johnny Laupsa-Borge et al. (2025). A Very-low-energy Fast Involves Increased Adipose Inflammatory Gene Expression: A 6-day Feeding Trial (FASTOMICS-6). (ekstern lenke)
- Kristin Løge Aanestad; Marie Austdal; Oddmund Nordgård et al. (2025). Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer. (ekstern lenke)
- Pouda Panahandeh Strømland; Bjørn-Erik Bertelsen; Kristin Viste et al. (2025). Effects of metformin on transcriptomic and metabolomic profiles in breast cancer survivors enrolled in the randomized placebo-controlled MetBreCS trial. (ekstern lenke)
- Liv Guro Engen Hanem; Øyvind Salvesen; Andre Madsen et al. (2021). Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study. (ekstern lenke)
- Mona Synnøve Nilsen; Regine Åsen Jersin; Arve Ulvik et al. (2020). 3-hydroxyisobutyrate, a strong marker of insulin resistance in type 2 diabetes and obesity that modulates white and brown adipocyte metabolism. (ekstern lenke)
- Vivian Lohmann Veum; Simon E Nitter Dankel; Jennifer Gjerde et al. (2012). The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss. (ekstern lenke)
- Monika Christensen; Ingvild Sveinsgjerd Fenne; Marianne Hauglid Flågeng et al. (2014). Estradiol determines the effects of PTH on ERα-dependent transcription in MC3T3-E1 cells. (ekstern lenke)
- Regine Åsen Jersin; Divya Sri Tallapragada; Linn Skartveit et al. (2023). Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism. (ekstern lenke)
- Harriet Johansson; Federica Bellerba; Debora Macis et al. (2024). Effect of metformin and lifestyle intervention on adipokines and hormones in breast cancer survivors: a pooled analysis from two randomized controlled trials. (ekstern lenke)
- Simon E Nitter Dankel; Jessica Svärd; Simone Matthä et al. (2014). COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size. (ekstern lenke)
- Nicholas A Sinnott-Armstrong; Isabel S. Sousa; Samantha Laber et al. (2021). A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density. (ekstern lenke)
- Melina Claussnitzer; Simon N Dankel; Kyoung-Han Kim et al. (2015). FTO obesity variant circuitry and adipocyte browning in humans. (ekstern lenke)
- Thomas Helland; Bjørn Naume; Steinar Hustad et al. (2020). Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen. (ekstern lenke)
- Atanaska Ivanova Doncheva; Frode Amador Norheim; Marit Hjorth et al. (2021). Serglycin Is Involved in Adipose Tissue Inflammation in Obesity. (ekstern lenke)
- Simon E Nitter Dankel; Dag Jone Stokke Fadnes; Anne-Kristin Stavrum et al. (2010). Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. (ekstern lenke)
- Linn Anja Slåke Vikøren; Aslaug Drotningsvik; Angela Kipesile Mwakimonga et al. (2018). Diets containing salmon fillet delay development of high blood pressure and hyperfusion damage in kidneys in obese Zucker fa/fa rats. (ekstern lenke)
- Ingrid Valheim Hagen; Anita Helland; Marianne Bratlie et al. (2023). Serum concentrations of amino acids and tryptophan metabolites are affected by consumption of a light breakfast: a clinical intervention study in adults with overweight or obesity. (ekstern lenke)
- Villy Våge; Roy Miodini Nilsen; Arnold Berstad et al. (2013). Predictors for remission of major components of the metabolic syndrome after biliopancreatic diversion with duodenal switch (BPDDS). (ekstern lenke)
- Ingrid Valheim Hagen; Anita Helland; Marianne Bratlie et al. (2019). TMAO, creatine and 1-methylhistidine in serum and urine are potential biomarkers of cod and salmon intake: a randomised clinical trial in adults with overweight or obesity. (ekstern lenke)
- Tuyen Hoang; Ingvild Sveinsgjerd Fenne; Andre Greger Madsen et al. (2013). cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1. (ekstern lenke)
- Jennifer Fernandez Gjerde; Marianne Hauglid; M Hauglid et al. (2008). Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism. (ekstern lenke)
- Regine Åsen Jersin; Divya Sri Priyanka Tallapragada; Andre Madsen et al. (2021). Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance. (ekstern lenke)
- Simon N Dankel; Therese Halvorsen Røst; Agné Kulyté et al. (2019). The Rho GTPase RND3 regulates adipocyte lipolysis. (ekstern lenke)
- Linn Anja Slåke Vikøren; Aslaug Drotningsvik; Svein Are Mjøs et al. (2018). Salmon fillet intake led to higher serum triacylglycerol in obese zucker Fa/Fa rats but not in normolipidemic Long-Evans rats. (ekstern lenke)
- Yuanhuang Chen; Lauren A. Marcath; Finn Magnus Eliassen et al. (2021). Effect of genetic variability in 20 pharmacogenes on concentrations of tamoxifen and its metabolites. (ekstern lenke)
- Mark Colin Gissler; Nathaly Anto-Michel; Jan Pennig et al. (2021). Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. (ekstern lenke)
- Anita Helland; Marianne Bratlie; Ingrid Valheim Hagen et al. (2022). Consumption of a light meal affects serum concentrations of one-carbon metabolites and B-vitamins. A clinical intervention study. (ekstern lenke)
- Ingrid Valheim Hagen; Anita Helland; Marianne Bratlie et al. (2016). High intake of fatty fish, but not of lean fish, affects serum concentrations of TAG and HDL-cholesterol in healthy, normal-weight adults: A randomised trial. (ekstern lenke)
- Bjørn Liaset; Qin Hao; Henry Jørgensen et al. (2011). Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome. (ekstern lenke)
- Linn Anja Slåke Vikøren; Aslaug Drotningsvik; Marthe Tønder Bergseth et al. (2017). Effects of baked and raw salmon fillet on lipids and n-3 PUFAs in serum and tissues in Zucker fa/fa rats. (ekstern lenke)
- Bente Berg Johansson; Karianne Fjeld; Marie Holm Solheim et al. (2017). Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation. (ekstern lenke)
- Anna M. Mc Laughlin; Thomas Helland; Fenja Klima et al. (2024). Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort. (ekstern lenke)
- Fedro Alessandro Peccatori; Giovanni Codacci-Pisanelli; Gunnar Mellgren et al. (2020). First-in-human pharmacokinetics of tamoxifen and its metabolites in the milk of a lactating mother: A case study. (ekstern lenke)
- Martha Eimstad Haugstøyl; Martin Cornillet; Kristina Strand et al. (2022). Distinct T cell subsets in adipose tissue are associated with obesity. (ekstern lenke)
- Kristin Viste; Marianne Aardal Grytaas; Melissa Jørstad et al. (2013). Efficacy of adrenal venous sampling is increased by point of care cortisol analysis. (ekstern lenke)
- Mette Schmedes; Claudia Balderas; Eli Kristin Aadland et al. (2018). The effect of lean-seafood and non-seafood diets on fasting and postprandial serum metabolites and lipid species: Results from a randomized crossover intervention study in healthy adults. (ekstern lenke)
- Harriet Johansson; Sara Gandini; Davide Serrano et al. (2016). A pooled analysis of CYP2D6 genotype in breast cancer prevention trials of low-dose tamoxifen. (ekstern lenke)
- Indu Dhar; Gard Frodahl Tveitevåg Svingen; Eva Ringdal Pedersen et al. (2022). Physical activity and risk of all-cause mortality in patients with stable angina pectoris: Effect modification by β-blocker treatment. (ekstern lenke)
- Seema A. Khan; Xinlei Mi; Yanfei Xu et al. (2023). Presurgical Oral Tamoxifen vs Transdermal 4-Hydroxytamoxifen in Women with Ductal Carcinoma in Situ: A Randomized Clinical Trial. (ekstern lenke)
- Gard Frodahl Tveitevåg Svingen; Hall Schartum-Hansen; Per Magne Ueland et al. (2014). Elevated plasma dimethylglycine is a risk marker of mortality in patients with coronary heart disease. (ekstern lenke)
- Iselin Thowsen Vildmyren; Huy John Vu Cao; Lina Bowitz Haug et al. (2018). Daily intake of protein from cod residual material lowers serum concentrations of nonesterified fatty acids in overweight healthy adults: A randomized double-blind pilot study. (ekstern lenke)
- P. H. Jensen; L. Cressey; Bjørn Tore Gjertsen et al. (1994). Cleaved intracellular plasminogen activator inhibitor-2 is a marker of apoptosis present in human myeloid leukemia cells. (ekstern lenke)
- Grethe Åstrøm Ueland; Paal Methlie; Marianne Øksnes et al. (2018). The short cosyntropin test revisited: new normal reference range using LC-MS/MS. (ekstern lenke)
- Ida Heir Hovland; Ingrid Sande Leikanger; Oddbjørg Stokkeland et al. (2019). Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study. (ekstern lenke)
- Astri Jeanette Meen; Atanaska Ivanova Doncheva; Yvonne Böttcher et al. (2023). Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue. (ekstern lenke)
- Mona Synnøve Bjune; Laurence Dyer; Johnny Laupsa-Borge et al. (2023). Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease. (ekstern lenke)
- Andre Madsen; Bjørg Almås; Ingvild Særvold Bruserud et al. (2022). Reference Curves for Pediatric Endocrinology: Leveraging Biomarker Z-Scores for Clinical Classifications. (ekstern lenke)
- Eva Ringdal Pedersen; Nora Tuseth; Simone Eussen et al. (2015). Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. (ekstern lenke)
- Monika Christensen; Ellen M Apalset; Yngve Nordbø et al. (2013). 1,25-dihydroxyvitamin D and the vitamin D receptor gene polymorphism apa1 influence bone mineral density in primary hyperparathyroidism. (ekstern lenke)
- Aslaug Drotningsvik; Øivind Midttun; Linn Anja Slåke Vikøren et al. (2019). Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys. (ekstern lenke)
- Vivian Lohmann Veum; Johnny Laupsa-Borge; Øyvin Andre Solberg Eng et al. (2017). Visceral adiposity and metabolic syndrome after very high-fat and low-fat isocaloric diets: A randomized controlled trial. (ekstern lenke)
- Andre Greger Madsen; Jan Inge Bjune; Lise Bjørkhaug et al. (2016). The cAMP-dependent protein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity. (ekstern lenke)
- Ernst Asbjørn Lien; Håvard Søiland; Steinar Lundgren et al. (2013). Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment. (ekstern lenke)
- Bjørn Liaset; Lise Madsen; Qin Hao et al. (2009). Fish protein hydrolysate elevates plasma bile acids and reduces visceral adipose tissue mass in rats. (ekstern lenke)
- Monika Christensen; Eva Kristine Ringdal Pedersen; Yngve Nordbø et al. (2012). Vitamin B6 status and interferon-γ-mediated immune activation in primary hyperparathyroidism. (ekstern lenke)
- Thomas Helland; Nina Henne; Ersilia Bifulco et al. (2017). Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients. (ekstern lenke)
- Silje Skrede; Ismael Gonzalez-Garcia; Luis Martins et al. (2017). Lack of ovarian secretions reverts the anabolic action of olanzapine in female rats. (ekstern lenke)
- Eirik Bratland; Geir Bredholt; Gunnar Mellgren et al. (2009). The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: The major autoantigen in autoimmune Addison's disease. (ekstern lenke)
- Marianne Bratlie; Ingrid Valheim Hagen; Anita Helland et al. (2020). Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: A randomised trial. (ekstern lenke)
- Jan-Inge Bjune; Samantha Laber; Laurence Dyer et al. (2025). IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells. (ekstern lenke)
- Olivera Bozickovic; Tuyen Hoang; Ingvild Sveinsgjerd Fenne et al. (2015). Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. (ekstern lenke)
- Jan-Inge Bjune; Laurence Dyer; Gro Vatne Røsland et al. (2019). The homeobox factor Irx3 maintains adipogenic identity. (ekstern lenke)
- Andrea DeCensi; Harriet Johansson; Thomas Helland et al. (2021). Association of CYP2D6 genotype and tamoxifen metabolites with breast cancer recurrence in a low-dose trial. (ekstern lenke)
- Alena M. Bubeck; Paul Urbain; Cathrine Horn et al. (2023). High-fat diet impact on intestinal cholesterol conversion by the microbiota and serum cholesterol levels. (ekstern lenke)
- Jessica Svärd; Therese Halvorsen Røst; Camilla Elise Nergård Sommervoll et al. (2019). Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice. (ekstern lenke)
- Rhian Gaenor Jacobsen; Fatemeh Mazloumi Gavgani; Gunnar Mellgren et al. (2016). DNA Topoisomerase IIα contributes to the early steps of adipogenesis in 3T3-L1 cells. (ekstern lenke)
- Jaspreet Kaur; Sung Yun Jung; Marie Austdal et al. (2024). Quantitative proteomics reveals serum proteome alterations during metastatic disease progression in breast cancer patients. (ekstern lenke)
- Paal Methlie; Simon E Nitter Dankel; Tone Sæterdal Myhra et al. (2013). Changes in adipose glucocorticoid metabolism before and after bariatric surgery assessed by direct hormone measurements. (ekstern lenke)
- Andre Madsen; Ninnie Oehme; Mathieu Roelants et al. (2019). Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty. (ekstern lenke)
- Harriet Johansson; Valentina Aristarco; Sara Gandini et al. (2019). Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer. (ekstern lenke)
- Linn A. Vikøren; Aslaug Drotningsvik; Øivind Midttun et al. (2021). Baked cod consumption delayed the development of kidney and liver dysfunction and affected plasma amino acid concentrations, but did not affect blood pressure, blood glucose or liver triacylglycerol concentrations in obese fa/fa Zucker rats.. (ekstern lenke)
- Simon N Dankel; Elise Grytten; Jan-Inge Bjune et al. (2020). COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. (ekstern lenke)
- Andre Madsen; Ninnie Oehme; Mathieu Roelants et al. (2020). Testicular Ultrasound to Stratify Hormone References in a Cross-Sectional Norwegian Study of Male Puberty. (ekstern lenke)
- Cathrine Horn; Johnny Laupsa-Borge; Amanda Andersen et al. (2021). Meal patterns associated with energy intake in people with obesity. (ekstern lenke)
- Anette Susanne Bøe; Geir Bredholt; Per Knappskog et al. (2004). Autoantibodies against 21-hydroxylase and side-chain cleavage enzyme in autoimmune Addison's disease are mainly immunoglobulin G1. (ekstern lenke)
- Elton Richard Kisanga; Gunnar Mellgren; Ernst Asbjørn Lien (2005). Excretion of hydroxylated metabolites of tamoxifen in human bile and urine. (ekstern lenke)
- Tuyen Hoang; Ingvild Sveinsgjerd Fenne; Carol Ann Cook et al. (2004). cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1. (ekstern lenke)
- MH Flageng; Marianne Hauglid; Line Leonore Haugan Moi et al. (2009). Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors. (ekstern lenke)
- Martha Haugstøyl; Martin Cornillet; Kristina Strand et al. (2023). Phenotypic diversity of human adipose tissue-resident NK cells in obesity. (ekstern lenke)
- Oukseub Lee; Latifa A. Bazzi; Yanfei Xu et al. (2024). A randomized Phase I pre-operative window trial of transdermal endoxifen in women planning mastectomy: Evaluation of dermal safety, intra-mammary drug distribution, and biologic effects. (ekstern lenke)
- Kristina Strand; Natalie Stiglund; Martha Eimstad Haugstøyl et al. (2022). Subtype-specific surface proteins on adipose tissue macrophages and their association to obesity-induced insulin resistance. (ekstern lenke)
- Anita Helland; Marianne Bratlie; Ingrid Valheim Hagen et al. (2021). Effect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial. (ekstern lenke)
- Jennifer Fernandez Gjerde; Elton Richard Kisanga; Marianne Hauglid et al. (2005). Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry. (ekstern lenke)
- Elton Richard Kisanga; Line Leonore Haugan Moi; Jennifer Gjerde et al. (2005). Induction of hepatic drug-metabolising enzymes and tamoxifen metabolite profile in relation to administration route during low-dose treatment in nude rats. (ekstern lenke)
- Alberto Falorni; Vittorio Bini; Corrado Betterle et al. (2015). Determination of 21-hydroxylase autoantibodies: Inter-laboratory concordance in the Euradrenal International Serum Exchange Program. (ekstern lenke)
- Anita Helland; Marianne Bratlie; Ingrid Valheim Hagen et al. (2017). High intake of fatty fish, but not of lean fish, improved postprandial glucose regulation and increased the n-3 PUFA content in the leucocyte membrane in healthy overweight adults: A randomised trial. (ekstern lenke)
- Cathrine Horn Sommersten; Johnny Laupsa-Borge; Amanda Iselin Olesen Andersen et al. (2022). Diets differing in carbohydrate cellularity and amount similarly reduced visceral fat in people with obesity - a randomized controlled trial (CARBFUNC). (ekstern lenke)
- Linn Anja Slåke Vikøren; Aslaug Drotningsvik; Marthe Tønder Bergseth et al. (2018). Intake of baked cod fillet resulted in lower serum cholesterol and higher long chain n-3 PUFA concentrations in serum and tissues in hypercholesterolemic obese Zucker fa/fa rats. (ekstern lenke)
- Marianne Aardal Grytaas; Siri S. Strømsøy; Jarle Rørvik et al. (2017). Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population. (ekstern lenke)
- Laura J. McCulloch; Tom J. Rawling; Kajsa Sjöholm et al. (2015). COL6A3 is regulated by leptin in human adipose tissue and reduced in obesity. (ekstern lenke)
- Villy Våge; Vetle Aaberge Sande; Gunnar Mellgren et al. (2014). Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: A two-year follow-up study. (ekstern lenke)
- Elin Strand; Eva Ringdal Pedersen; Gard Frodahl Tveitevåg Svingen et al. (2017). Serum acylcarnitines and risk of cardiovascular death and acute myocardial infarction in patients with stable angina pectoris. (ekstern lenke)
- Elise Grytten; Johnny Laupsa-Borge; Kaya Sinem Cetin et al. (2025). Inflammatory markers after supplementation with marine n-3 or plant n-6 PUFAs: A randomized double-blind crossover study. (ekstern lenke)
- Eli Kristin Aadland; Ingvild Eide Graff; Charles Lavigne et al. (2016). Lean seafood intake reduces postprandial c-peptid and lactate concentrations in healthy adults in a randomized controlled trial with a crossover design. (ekstern lenke)
- Ingvild Sveinsgjerd Fenne; Tuyen Hoang; Marianne Hauglid et al. (2008). Recruitment of coactivator glucocorticoid receptor interacting protein 1 to an estrogen receptor transcription complex is regulated by the 3',5'-cyclic adenosine 5'-monophosphate-dependent protein kinase. (ekstern lenke)
- Indu Dhar; Vegard Lysne; Arve Ulvik et al. (2023). Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study. (ekstern lenke)
- Simon E Nitter Dankel; Eirik Magnus Meek Degerud; Kamil Borkowski et al. (2014). Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice. (ekstern lenke)
- Bjørn-Erik Bertelsen; Kristin Viste; Thomas Helland et al. (2021). Simultaneous Quantification of Aromatase Inhibitors and Estrogens in Postmenopausal Breast Cancer Patients. (ekstern lenke)
- Andre Greger Madsen; Olivera Bozickovic; Jan Inge Bjune et al. (2015). Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). (ekstern lenke)
- Marianne Hauglid Flågeng; Alexey Larionov; Jürgen Geisler et al. (2016). Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers. (ekstern lenke)
- Davide Serrano; Harriet Johansson; Bjørn-Erik Bertelsen et al. (2024). Drug and biomarker tissue levels in a randomized presurgical trial on exemestane alternative schedules. (ekstern lenke)
- Thomas Helland; Jennifer Gjerde; Simon N Dankel et al. (2015). The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells. (ekstern lenke)
- Hans Jørgen Nielsen; Bjørn Gunnar Nedrebø; Alexander Fosså et al. (2022). Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy. (ekstern lenke)
- Mette Schmedes; Asker Brejnrod; Eli Kristin Aadland et al. (2018). The effect of lean-seafood and non-seafood diets on fecal metabolites and gut microbiome: results from a randomized crossover intervention study. (ekstern lenke)
- Natalie Stiglund; Kristina Strand; Martin Cornillet et al. (2019). Retained NK cell phenotype and functionality in non-alcoholic fatty liver disease. (ekstern lenke)
- Maria O'Keeffe; Åge Oterhals; Linn Anja Slåke Vikøren et al. (2023). Dietary fish intake increased the concentration of soluble ACE2 in rats. Can fish consumption reduce the risk of COVID-19 infection through interception of SARS-CoV-2 by soluble ACE2?. (ekstern lenke)
- Gard Frodahl Tveitevåg Svingen; Hall Schartum-Hansen; Eva Ringdal Pedersen et al. (2016). Prospective associations of systemic and urinary choline metabolites with incident type 2 diabetes. (ekstern lenke)
- Ulrike Lehmann; Hanne Rosendahl Gjessing; Frank Hirche et al. (2015). Efficacy of fish intake on Vitamin D status: A meta-analysis of randomized controlled trials. (ekstern lenke)
- Johan Lund; Anne Lilybert J. Jacob; R. Aesöy et al. (1998). Biochemical and functional analysis of nuclear receptors as targets in cAMP-dependent control of bovine CYP17. (ekstern lenke)
- Jan-Inge Bjune; Christine Haugen; Oddrun Anita Gudbrandsen et al. (2018). IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity. (ekstern lenke)
- OT Brustugun; Gunnar Mellgren; BT Gjertsen et al. (1995). Sensitive and rapid detection of _b-galactosidase expression in intact cells by microinjection of fluorescent substrate. (ekstern lenke)
- Tone Nygaard Flølo; Alexander Fosså; Jonas Ingolf Petersson Nedkvitne et al. (2023). Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy. (ekstern lenke)
- Melina Claussnitzer; Simon E Nitter Dankel; Bernward Klocke et al. (2014). Leveraging cross- species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. (ekstern lenke)
- BT Gjertsen; Gunnar Mellgren; A Otten et al. (1995). Novel Rp-cAMPS analogs as tools for inhibition of type I cAMP-dependent protein kinase in cell culture. Basal cAMP-kinase activity modulates hepatocyte DNA replication and interleukin-1_b action. (ekstern lenke)
- Kari Espolin Fladmark; Bjørn Tore Gjertsen; Anders Molven et al. (1997). Gap junctions and growth control in liver regeneration and in isolated rat hepatocytes. (ekstern lenke)
- Monika Christensen; Simon E Nitter Dankel; Yngve Nordbø et al. (2011). Primary hyperparathyroidism influences the expression of inflammatory and metabolic genes in adipose tissue. (ekstern lenke)
- Caroline Jensen; Cathrine Horn Sommersten; Johnny Laupsa-Borge et al. (2024). Quality and quantity of carbohydrates, faecal short-chain fatty acids and gastrointestinal symptoms– results from a randomised, controlled trial (CARBFUNC). (ekstern lenke)
- Mette Schmedes; Eli Kristin Aadland; Ulrik Kræmer Sundekilde et al. (2016). Lean-seafood intake decreases urinary markers of mitochondrial lipid and energy metabolism in healthy subjects: Metabolomics results from a randomized crossover intervention study. (ekstern lenke)
- Oddrun Anita Gudbrandsen; Yosuke Kodama; Svein Are Mjøs et al. (2014). Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats. (ekstern lenke)
- Davide Serrano; Sara Gandini; Parjhitham Thomas et al. (2023). Efficacy of Alternative Dose Regimens of Exemestane in Postmenopausal Women With Stage 0 to II Estrogen Receptor-Positive Breast Cancer: A Randomized Clinical Trial. (ekstern lenke)
- Jennifer Gjerde; Jurgen Geisler; Steinar Lundgren et al. (2007). A study of association between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferae 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady sate tamoxifen treatment. (ekstern lenke)
- Eli Kristin Aadland; Charles Lavigne; Ingvild Eide Graff et al. (2015). Lean-seafood intake reduces cardiovascular lipid risk factors in healthy subjects: results from a randomized controlled trial with a crossover design. (ekstern lenke)
- Johan Lund; Marit Bakke; Gunnar Mellgren et al. (1997). Transcriptional regulation of the bovine CYP17 gene by cAMP. (ekstern lenke)
- Elise Grytten; Johnny Laupsa-Borge; Pavol Bohov et al. (2021). Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study. (ekstern lenke)
- Grethe Åstrøm Ueland; Paal Methlie; Ralf Kellmann et al. (2017). Simultaneous assay of cortisol and dexamethasone improved diagnostic accuracy of the dexamethasone suppression test. (ekstern lenke)
- Olivera Bozickovic; Linn Skartveit; Agnete Svendsen et al. (2018). A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells. (ekstern lenke)
- Siegfried Ussar; Kevin Lee; Simon N Dankel et al. (2014). ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.. (ekstern lenke)
- Jennifer Gjerde; Jürgen Geisler; Steinar Lundgren et al. (2010). Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer. (ekstern lenke)
- Davide Serrano; Matteo Lazzeroni; Carlo–Federico Zambon et al. (2011). Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial. (ekstern lenke)
- Gunnar Mellgren; T Bruland; A.P Døskeland et al. (1997). Synergistic antiproliferative actions of cyclic adenosine 3',5'-monophosphate, interleukin-1beta, and activators of Ca%2%+/calmodulin-dependent protein kinase in primary hepatocytes. (ekstern lenke)
- Eirik Wilberg Rebnord; Elin Strand; Øivind Midttun et al. (2017). The kynurenine:tryptophan ratio as a predictor of incident type 2 diabetes mellitus in individuals with coronary artery disease. (ekstern lenke)
- Marianne Hauglid Flågeng; Stian Knappskog; Ben P. Haynes et al. (2013). Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue. (ekstern lenke)
- Miriam Ejarque; Marianne Borlaug; Núria Vilarrasa et al. (2017). Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery. (ekstern lenke)
- Lisa Marie Dale Grymyr; Gunnar Mellgren; Adrian McCann et al. (2024). Preoperative risk factors associated with left ventricular dysfunction after bariatric surgery. (ekstern lenke)
- Marianne Hauglid Flågeng; Stian Knappskog; Jennifer Gjerde et al. (2015). Estrogens correlate with PELP1 expression in ER positive breast cancer. (ekstern lenke)
- Mohammed Adhmed Abdel Ghafar Kareem Eldin; Håvard G Frøysa; Odd Andre Karlsen et al. (2018). LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. (ekstern lenke)
- Hanne Rosendahl-Riise; Hans Jørgen Nielsen; Gunnar Mellgren et al. (2013). Energy intake, nutritional status and weight reduction in patients one year after laparoscopic sleeve gastrectomy. (ekstern lenke)
- Karen Klepsland Mauland; Øyvin Andre Solberg Eng; Sigmund Ytre-Hauge et al. (2017). High visceral fat percentage is associated with poor outcome in endometrial cancer. (ekstern lenke)
- Harriet Johansson; Aliana Guerrieri-Gonzaga; Sara Gandini et al. (2024). Alternative dosing regimen of exemestane in a randomized presurgical trial: the role of obesity in biomarker modulation. (ekstern lenke)
- Christine Haugen; Vegard Lysne; Ingfrid S. Haldorsen et al. (2022). MRI adipose tissue segmentation and quantification in R (RAdipoSeg). (ekstern lenke)
- Simon E Nitter Dankel; Tuyen Hoang; Marianne Hauglid Flågeng et al. (2010). cAMP-mediated regulation of HNF-4 alpha depends on the level of coactivator PGC-1 alpha. (ekstern lenke)
- Johnny Laupsa-Borge; Elise Grytten; Pavol Bohov et al. (2023). Sex-specific responses in glucose-insulin homeostasis and lipoprotein-lipid components after high-dose supplementation with marine n-3 PUFAs in abdominal obesity: a randomized double-blind crossover study. (ekstern lenke)
- Grethe Åstrøm Ueland; Ralf Kellmann; Melissa Davidsen Jørstad et al. (2021). Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children. (ekstern lenke)
- Gunnar Mellgren; Olav Karsten Vintermyr; Ragnar Bøe et al. (1993). Hepatocyte DNA replication is abolished by inhibitors selecting protein phosphatase 2A rather than phosphatase 1. (ekstern lenke)
- Andre Madsen; Ingvild Særvold Bruserud; Bjørn-Erik Bertelsen et al. (2020). Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty. (ekstern lenke)
- Monika Christensen; Dag Jone Stokke Fadnes; Therese Halvorsen Røst et al. (2018). Inflammatory markers, the tryptophan-kynurenine pathway, and Vitamin B status after bariatric surgery. (ekstern lenke)
- Therese Halvorsen Røst; Line Leonore Haugan Moi; Kjetil Berge et al. (2009). A pan-PPAR ligand induces hepatic fatty acid oxidation in PPAR alpha-/- mice possibly through PGC-1 mediated PPAR delta coactivation. (ekstern lenke)
- Peder Braadland; Helene Hartvedt Grytli; Håkon Andre Ramberg et al. (2016). Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism. (ekstern lenke)
- Line Leonore Haugan Moi; Marianne Hauglid Flågeng; Jennifer Gjerde et al. (2012). Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer. (ekstern lenke)
- Jennifer Gjerde; Sara Gandini; Aliana Guerrieri-Gonzaga et al. (2012). Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide. (ekstern lenke)
- Oddrun Anita Gudbrandsen; Simon N Dankel; Lillian Skumsnes et al. (2019). Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis. (ekstern lenke)
- Ingvild Sveinsgjerd Fenne; Thomas Helland; Marianne Hauglid Flågeng et al. (2013). Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of MCF-7 breast cancer cells. (ekstern lenke)
- Thomas Helland; Kari Britt Hagen; Martha Eimstad Haugstøyl et al. (2019). Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database. (ekstern lenke)
- Cathrine Horn; Eirin Semb Gjerde; Johnny Laupsa-Borge et al. (2023). Relationship between Ketones, Ghrelin, and, Appetite on Isocaloric Diets with Varying Carbohydrate Quality and Amount: Results from a Randomized Controlled Trial in People with Obesity (CARBFUNC). (ekstern lenke)
- Lifeng Wang; Nicholas A Sinnott-Armstrong; Alexandre Wagschal et al. (2020). A MicroRNA Linking Human Positive Selection and Metabolic Disorders. (ekstern lenke)
- Marianne Bratlie; Ingrid Valheim Hagen; Anita Helland et al. (2020). Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial. (ekstern lenke)
- K.E. Flatmark; B.T. Gjertsen; Anders Molven et al. (1997). Gap junctions and growth control in liver regeneration and in isolated rat hepatocytes. (ekstern lenke)
- Johan Lund; Anne L. Jacob; Reidun Æsøy et al. (1998). Biochemical and functional analysis of nuclear receptors as targets in cAMP-dependent control of bovine CYP17. (ekstern lenke)
- G Houge; B Robaye; TS Eikholm et al. (1995). Fine mapping of 28S rRNA sites specifically cleaved in cells undergoing apoptosis. (ekstern lenke)
- Gunnar Mellgren; Olav Karsten Vintermyr; SO Døskeland (1995). Okadaic acid, cAMP, and selected nutrients inhibit hepatocyte proliferation at different stages in G%b: Modulation of the cAMP effect by phosphatase inhibitors and nutrients. (ekstern lenke)
- Linda Aumo; Marte Rusten; Gunnar Mellgren et al. (2010). Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. (ekstern lenke)
- Monika Christensen; Ingvild Sveinsgjerd Fenne; Yngve Nordbø et al. (2015). Novel inflammatory biomarkers in primary hyperparathyroidism. (ekstern lenke)
- Reidun Æsøy; Gunnar Mellgren; Ken-Ichirou Morohashi et al. (2002). Activation of cAMP-dependent protein kinase increases the protein level of steroidogenic factor-1. (ekstern lenke)
- Ryoko Higa; Shirin Pourteymour; Pratibha Shrikant Kolan et al. (2025). Hepatic lipid metabolism is altered in Ubiad1+/- mice of both sexes. (ekstern lenke)
- Line Leonore Haugan Moi; Marianne Hauglid Flågeng; Sara Gandini et al. (2010). Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue. (ekstern lenke)
Konferanseforedrag
- Gunnar Mellgren (2004). Hormonal regulation of the Glucocorticoid receptor interacting protein 1 (GRIP1). (ekstern lenke)
- Gunnar Mellgren (2004). Prisforedrag - Novo Nordisk pris for fremragende forskning i endokrinologi. (ekstern lenke)
- Jan-Inge Bjune; Samantha Laber; Laurence Dyer et al. (2021). Epigenetic control of adipogenesis by Irx3. (ekstern lenke)
- Tone Nygaard Flølo; Alexander Fosså; Jo Erling Riise Waage et al. (2023). Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy. (ekstern lenke)
- Odd Terje Brustugun; Kari Espolin Fladmark; Gunnar Mellgren et al. (1998). Ultrarapid apoptosis induction in a variety of cell types injected with phosphatase inhibitors is mediated through Ca2 /calmodulin dependent protei kinase activity. (ekstern lenke)
- Therese Halvorsen Røst; Gunnar Mellgren; Rolf Kristian Berge (2004). Tetradecylthioacetic acid induces ligand dependent coactivation of PPARs by PGC-1 and SRC coactivators. (ekstern lenke)
- Ingrid Valheim Hagen; Anita Helland; Marianne Bratlie et al. (2012). Effects of a high fish intake on lipid and bile acid levels in serum and feces from overweight and obese adults. (ekstern lenke)
- Marianne Bratlie; Ingrid Valheim Hagen; Anita Helland et al. (2012). Effects of a high fish intake on leukocyte membrane fatty acid composition and leukocyte function ex vivo in overweight and obese adults. (ekstern lenke)
- Gunnar Mellgren (2006). NUCLEAR RECEPTORS IN ENDOCRINE FUNCTION AND DISEASE. (ekstern lenke)
- Anita Helland; Marianne Bratlie; Ingrid Valheim Hagen et al. (2012). Effect of a high fish intake on glucose tolerance and GLP-1 levels in overweight and obese adults. (ekstern lenke)
- Therese Halvorsen Røst; Gunnar Mellgren; Rolf Kristian Berge (2005). A pan-PPAR ligand induces differential coactivation of PPARs by SRCs and PGC-1. (ekstern lenke)
- Gunnar Mellgren (2007). Role of cAMP in Regulation of the Nuclear Receptor Coactivator GRIP1. (ekstern lenke)
- Gunnar Mellgren (2009). Hva kan vi lære av sykelig fedme? Fedme og genekspresjon. (ekstern lenke)
- Gunnar Mellgren (2008). Nuclear Receptor Coactivators. (ekstern lenke)
- Gunnar Mellgren (2008). Marine macronutrients, metabolic homeostasis and obesity. (ekstern lenke)
- Mona Synnøve Bjune; Laurence Dyer; Matthias Blüher et al. (2021). Altered hepatic HIBCH expression is associated with hepatic lipid accumulation and fatty liver. (ekstern lenke)
- Mona Synnøve Nilsen; Regine Åsen Jersin; Andre Madsen et al. (2018). Amino acid metabolism in adipocytes. (ekstern lenke)
- Eli Kristin Aadland; Charles Lavigne; Ingvild Eide Graff et al. (2015). Lean seafood intake reduces cardiovascular risk factors in healthy subjects. (ekstern lenke)
- E Bratland; G Bredholt; Per Knappskog et al. (2005). Cellular immunity to 21-hydroxylase in patients with autoimmune Addison's disease. (ekstern lenke)
- Mona Synnøve Nilsen; Regine Åsen Jersin; Adrian McCann et al. (2019). Circulating 3-hydroxyisobutyrate (3-HIB) as a clinical marker of prediabetes and T2D in patients with obesity. (ekstern lenke)
- Gunnar Mellgren (2005). Regulering av steroidhormonreseptorer ved protein-protein interaksjon. (ekstern lenke)
- Gunnar Mellgren (2004). Nuclear Receptor Interacting Proteins as Molecular Targets in Breast Carcinoma. (ekstern lenke)
- Gunnar Mellgren (2004). Intracellulære hormonreseptorer - betydning av nye koregulator proteiner. (ekstern lenke)
- Gunnar Mellgren (2005). Endocrine regulation of a nuclear receptor coactivator. (ekstern lenke)
- Gunnar Mellgren (2004). Hormonal regulation of nuclear receptor coactivator GRIP1. (ekstern lenke)
- Gunnar Mellgren (2004). cAMP-depentent protein kinase regulates ubiquitin-proteasome mediated degradation of the nuclear receptor coactivator GRIP1. (ekstern lenke)
- Gunnar Mellgren (2010). Oppregulering av østrogen-receptor koaktivatorer og HER-2/neu under endokrin behandling av brystkreft. (ekstern lenke)
- Gunnar Mellgren (2010). Presentasjon av strategisk satsing innen ernæring og overvekt. (ekstern lenke)
- Gunnar Mellgren; Simon E Nitter Dankel (2009). Bariatric surgery dramatically alters global gene expression in adipose tissue. (ekstern lenke)
- Gunnar Mellgren (2009). Adipogen – en studie av fettvev til pasienter som har gjennomgått overvektskirurgi. (ekstern lenke)
- Gunnar Mellgren (2012). Novel transcription factors in obesity. (ekstern lenke)
- Gunnar Mellgren (2012). Homeobox transcription factors IRX3 and 5 in obesity. (ekstern lenke)
- Simon E Nitter Dankel; Eirik Magnus Meek Degerud; Even Fjære et al. (2012). Weight cycling affects adipose tissue genes involved in circadian rhythm and lipid metabolism. (ekstern lenke)
- Simon E Nitter Dankel; Dag Jone Stokke Fadnes; Andrea Christoforou et al. (2012). Integrative genomics links homeobox transcription factors to intra-abdominal obesity. (ekstern lenke)
Konferanseposter
- Simon E Nitter Dankel; Tuyen Hoang; Jørn V. Sagen et al. (2008). cAMP/PKA Exerts Differential Effects on GRIP1- and PGC-1α-Mediated HNF-4α Transcriptional Activity in HepG2 and COS-1 Cells. (ekstern lenke)
- Simon E Nitter Dankel; Tuyen Hoang; Jørn V. Sagen et al. (2008). cAMP Regulates Nuclear Receptor Coactivator GRIP1–Mediated Coactivation of HNF-4alpha in HepG2 Cells. (ekstern lenke)
- Marianne Hauglid Flågeng; Stian Knappskog; Alexey Larionov et al. (2010). Epidermal growth factor receptors (ErbB/HER) and the ligand Neuregulin 1 (NRG1) increase in breast tumors during short time treatment with aromatase inhibitors. (ekstern lenke)
- Linn Anja Slåke Vikøren; Aslaug Drotningsvik; Gunnar Mellgren et al. (2015). INTAKE OF FISH PROTEIN AND EFFECTS ON GLUCOSE REGULATION AND LIPID METABOLISM IN OBESE ZUCKER RATS. (ekstern lenke)
- Marianne Hauglid Flågeng; Line Leonore Haugan Moi; Sara Gandini et al. (2010). Expression of Steroid Receptor Coactivators and HER-2/neu in normal and malignant breast tissue in controls and tamoxifen treated patients. (ekstern lenke)
- Monika Christensen; Yngve Nordbø; Jan Erik Varhaug et al. (2013). Vitamin D levels in patients with primary hyperparathyroidism; a follow-up study after parathyroidectomy. (ekstern lenke)
- Siri Lunde; Thomas Helland; Janne Jonassen et al. (2018). A prospective, longitudinal, breast cancer biobank (PBCB) in western Norway. (ekstern lenke)
- Jennifer Gjerde; Aliana Guerrieri-Gonzaga; Bernardo Bonanni et al. (2010). Distribution of tamoxifen and five metabolites into normal and malignant human breast cancer tissue during conventional and low dose treatment. (ekstern lenke)
- Erik Wilhelm Vinnes; Kristin Moberg Aakre; Johan Fernø et al. (2024). Long-term effect of bariatric surgery on circulating GDF15 concentrations. (ekstern lenke)
- Vivian Lohmann Veum; Simon E Nitter Dankel; Jennifer Gjerde et al. (2011). The nuclear receptors NURR77, NURR1 and NOR1 in obesity and during fat loss. (ekstern lenke)
- Lise Bjørkhaug; Lorentze Hornnes; Alba Kaci et al. (2017). Functional analysis of various HNF4A variants identifies increased transactivation function of R85W causing the mutation specific phenotype of neonatal hyperinsulinism and Fanconi syndrome. (ekstern lenke)
- Mari Bergsvåg; Ingvild Sveinsgjerd Fenne; Tuyen Hoang et al. (2008). SEARCH FOR UBIQUITINATION SITES AND UBIQUTIN-RELATED PHOSPHORYLATION SITES IN THE STEROID RECEPTOR COACTIVATOR GRIP1. (ekstern lenke)
- Jennifer Fernandez Gjerde; Marianne Hauglid; Harald Breilid et al. (2007). Effect of CYP2D6 and SULT1A1 Genotypes on the serum concentration of 4-OHtamoxifen and 4-OH-N-Demethyltamoxifen during steady state treatment of breast cancer patients. (ekstern lenke)
- Marianne Hauglid; Line Leonore Haugan Moi; Michael Dixon et al. (2008). Changes in mRNA expression levels of steroid receptor coactivators correlate with treatment response to aromatase inhibition in human breast cancer. (ekstern lenke)
- Marianne Hauglid Flågeng; Stian Knappskog; Per Eystein Lønning et al. (2011). The nuclear receptor coactivator PELP1/MNAR is positively correlated with estrogen levels in breast cancer patients. (ekstern lenke)
- Eva Ringdal Pedersen; Nora Tuseth; Simone Eussen et al. (2014). Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. (ekstern lenke)
- Gunnar Mellgren; Tuyen Hoang; Jørn V. Sagen et al. (2007). Regulation of HNF-4alpha transcriptional activity by the coactivators GRIP1 and PGC-1alpha. (ekstern lenke)
- Jennifer Gjerde; M Hauglid; H Breilid et al. (2005). Relationship between CYP2D6 and SULT1A1 genotype and serum concentration of tamoxifen and its metabolites during steady state treatment in breast cancer patients. (ekstern lenke)
- Monika Christensen; Eva Kristine Ringdal Pedersen; Yngve Nordbø et al. (2012). Systemic Inflammation in Primary Hyperparathyroidism: Influences on Plasma Vitamin B6 Levels and Interferon-γ Mediated Immune Activation. (ekstern lenke)
- Marianne Hauglid Flågeng; Alexey Larionov; Jürgen Geisler et al. (2012). Inverse regulation of Neuregulin 1 and HER-3 during treatment with aromatase inhibitors of estrogen receptor-positive breast cancer. (ekstern lenke)
- Christine Haugen; Simon E Nitter Dankel; K. Han Kim et al. (2013). Deficiency of Irx5 is associated with decreased fat mass in male CD1 mice. (ekstern lenke)
- Marianne Hauglid Flågeng; Line Leonore Haugan Moi; J. Michael Dixon et al. (2009). HER-2/neu and nuclear receptor coactivators are upregulated in breast cancer tumors during estrogen deprivation. (ekstern lenke)
- Jennifer Gjerde; Jürgen Geisler; Steinar Lundgren et al. (2009). Relations between FSH, SHBG and tamoxifen metabolism during steady state tamoxifen treatment. (ekstern lenke)
- Christine Haugen; Simon E Nitter Dankel; K. Han Kim et al. (2013). Role of homeobox transcription factor IRX5 in obesity and metabolic health. (ekstern lenke)
- Therese Halvorsen Røst; Oddrun Anita Gudbrandsen; Karl Johan Tronstad et al. (2004). PPAR-delta activation in relation to reduction of adipose tissue. (ekstern lenke)
- Sigve Ladstein; Gunn A. Hildrestrand; Harald K. Halvorsen et al. (2005). Molecular cloning and characterization of estrogen receptors in Atlantic salmon (Salmo salar). (ekstern lenke)
- Ingvild Sveinsgjerd Fenne; Tuyen Hoang; Gunnar Mellgren (2005). Hormonal regulation of the intranuclear localization of the nuclear hormone receptor coactivator GRIP1. (ekstern lenke)
- Line Haugan; Gunnar Mellgren (2004). Tamoxifen metabolism and induction of hepatic drug metabolising enzymes in nude rats. (ekstern lenke)
- Divya Sri Priyanka Tallapragada; Samantha Laber; Gunnar Mellgren et al. (2019). Generation and validation of immortalized human paired subcutaneous and omental adipocyte models to study obesity. (ekstern lenke)
- Therese Halvorsen Røst; Gunnar Mellgren; Rolf Kristian Berge (2005). A pan-PPAR ligand induces differential coactivation of PPARs by SRCs and PGC-1. (ekstern lenke)
- Christine Haugen; Simon N Dankel; K. Han Kim et al. (2014). Role of homeobox transcription factors IRX3 and IRX5 in mitochondrial development and activity in adipose tissue. (ekstern lenke)
- Divya Sri Priyanka Tallapragada; Gunnar Mellgren; Simon N Dankel (2018). Gene marker panel for omental and subcutaneous adipocytes in humans. (ekstern lenke)
- Simon E Nitter Dankel; Dag Jone Stokke Fadnes; Oddrun Anita Gudbrandsen et al. (2011). Prediction of obesity candidate genes by multiple gene expression analyses of adipose tissue. (ekstern lenke)
- Tuyen Hoang; Ingvild Sveinsgjerd Fenne; Mona Johannessen et al. (2006). ROLES OF cAMP RESPONSE ELEMENT BINDING PROTEIN (CREB) IN REGULATION OF GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 (GRIP1). (ekstern lenke)
- Marianne Hauglid Flågeng; Olivera Bozickovic; Linn Skartveit et al. (2014). Steroid receptor coactivators during short-term estrogen deprivation. (ekstern lenke)
- Regine Jersin; Andre Madsen; Aron Willems et al. (2018). Impaired D-serine uptake in adipocytes promotes oxidative stress and visceral obesity. (ekstern lenke)
- Ingvild Sveinsgjerd Fenne; Tuyen Hoang; Gunnar Mellgren (2006). Endocrine regulation of the nuclear receptor coactivator GRIP1 through the cAMP-signalling pathway. (ekstern lenke)
- Tuyen Hoang; Ingvild Sveinsgjerd Fenne; Mari Bergsvåg et al. (2009). The Role of PKA and CREB in regulation of the Steroid Receptor Coactivator GRIP1/SRC-2. (ekstern lenke)
- Vivian Lohmann Veum; Johnny Laupsa-Borge; Øyvin Solberg Eng et al. (2014). A moderate energy-restricted very-high-fat diet reduces fat mass and improves metabolic health in abdominally obese middle-aged men. (ekstern lenke)
- Ingvild Sveinsgjerd Fenne; Marianne Hauglid Flågeng; Tuyen Hoang et al. (2009). Role of the cAMP-PKA Signaling Pathway in the Regulation of ERalpha-dependent transcription by Steroid Receptor Coactivators in Breast Cancer Cells. (ekstern lenke)
- Line Leonore Haugan Moi; Elton Richard Kisanga; Jennifer Gjerde et al. (2004). Tamoxifen metabolism and induction of hepatic drug-metabolizing enzymes in nude rats. (ekstern lenke)
- Mona Synnøve Nilsen; Regine Åsen Jersin; Andre Madsen et al. (2019). Adipocyte amino acid metabolism in obesity-related metabolic diseases. (ekstern lenke)
- Marthe Bergseth; Aslaug Drotningsvik; Linn Anja Slåke Vikøren et al. (2016). Effects of intake of baked and raw fish on serum lipids and fatty acid composition in obese rats. (ekstern lenke)
- Linn Anja Slåke Vikøren; Aslaug Drotningsvik; Iselin Thowsen Vildmyren et al. (2016). Effects of salmon filet intake on blood pressure regulation. (ekstern lenke)
- Jennifer Gjerde; Jurgen Geisler; Steinar Lundgren et al. (2007). A study of association between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferae 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady sate tamoxifen treatment. (ekstern lenke)
- Jennifer Fernandez Gjerde; Marianne Hauglid; Harald Breilid et al. (2005). Relationship between CYP2D6 and SULT1A1 genotypes and serum concentrations of tamoxifen and its metabolites during steady state treatment in breast cancer patients. (ekstern lenke)
- Line Leonore Haugan Moi; Elton Richard Kisanga; Jennifer Gjerde et al. (2005). Effects of low-dose tamoxifen treatment on expression of drug-metabolising enzymes in rat liver in relation to administration route. (ekstern lenke)
- Tuyen Hoang; Ingvild Sveinsgjerd Fenne; Ernst Asbjørn Lien et al. (2005). CHARACTERIZATION OF THE MOLECULAR MECHANISMS BY WHICH THE LEVEL OF NUCLEAR HORMONE RECEPTOR COACTIVATOR GRIP1 IS REGULATED. (ekstern lenke)
- Iselin Thowsen Vildmyren; John Cao; Ida Ulrikke Karlsen et al. (2016). Effects of water soluble and water insoluble cod protein on lipid metabolism in overweight adults. (ekstern lenke)
- Eli Kristin Aadland; Ingvild Eide Graff; Bjørn Liaset et al. (2013). A controlled randomized intervention study with lean seafood vs terrestrial animal proteins in healthy subjects: data on body mass and body composition. (ekstern lenke)
- Tuyen Hoang; Simon E Nitter Dankel; Dag Jone Stokke Fadnes et al. (2010). Gene Expression Profile of Nuclear Receptors and Coregulators in Adipose Tissues in Morbid Obesity and after Profound Fat Loss. (ekstern lenke)
- Simon E Nitter Dankel; Dag Jone Stokke Fadnes; Anne-Kristin Stavrum et al. (2010). From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery. (ekstern lenke)
- Ingvild Sveinsgjerd Fenne; Marianne Hauglid Flågeng; Thomas Helland et al. (2011). Characterization of Global Gene Expression in Breast Cancer Cells after cAMP/PKA-mediated downregulation of Steroid Receptor Coactivator 2. (ekstern lenke)
- Mette Schmedes; Christian Clement Yde; Eli Kristin Aadland et al. (2014). Metabolomic studies on the urinary response to a diet based on either lean seafood or other protein sources. (ekstern lenke)
- Simon E Nitter Dankel; Dag Jone Stokke Fadnes; Oddrun Anita Gudbrandsen et al. (2010). Low Omental Expression of Fat Loss-Associated Homeobox Transcription Factors in Morbid Obesity. (ekstern lenke)
- Monika Christensen; Ingvild Sveinsgjerd Fenne; Marianne Hauglid Flågeng et al. (2009). PTH inhibits ligand-dependent activation of estrogen receptor alfa in MC3T3 osteoblasts. (ekstern lenke)
- Johan Fernø; Aron Willems; Simon N Dankel et al. (2014). SLC7A10, a novel adipocyte-enriched gene with a potential role in adipocyte differentiation. (ekstern lenke)
- Mona Synnøve Bjune; Laurence Dyer; Adrian McCann et al. (2022). Altered hepatic HIBCH expression is associated with hepatic lipid accumulation and fatty liver. (ekstern lenke)
- Jan-Inge Bjune; Christine Haugen; Oddrun Anita Gudbrandsen et al. (2018). Irx5 regulates body weight via amyloid precursor protein and mitochondrial respiration in adipocytes. (ekstern lenke)
- Jan-Inge Bjune; Andre Madsen; Lise Bjørkhaug et al. (2016). PKA downregulates glucose-6phosphatase Expression through RORα and SRC2. (ekstern lenke)
- Caroline Jensen; Gunnar Mellgren; Simon N Dankel et al. (2024). Quality and quantity of carbohydrates, fecal SCFAs and gastrointestinal symptoms - results from a RCT (CARBFUNC). (ekstern lenke)
- Jan-Inge Bjune; Christine Haugen; Oddrun Anita Gudbrandsen et al. (2018). Irx5 regulates body weight via amyloid precursor protein (App) and mitochondrial respiration in adipocytes. (ekstern lenke)
- Andre Madsen; Olivera Bozickovic; Jan-Inge Bjune et al. (2016). Repression of liver SRC-2 by metformin inhibits glucose, lipid and cholesterol biosynthesis. (ekstern lenke)
- Iselin Thowsen Vildmyren; John Cao; Ida Ulrikke Karlsen et al. (2016). Effects of water soluble and water insoluble cod protein on lipid metabolism in overweight adults. (ekstern lenke)
- Monika Christensen; Ingvild Sveinsgjerd Fenne; Marianne Hauglid Flågeng et al. (2009). PTH inhibits ligand-dependent activation of estrogen receptor alfa in MC3T3 Osteoblasts. (ekstern lenke)
- Monika Christensen; Simon E Nitter Dankel; Yngve Nordbø et al. (2011). Differential Expression of Inflammatory and Metabolic Genes in Adipose Tissue of Patients with Primary Huperparathyroidism. (ekstern lenke)
- Eirik Magnus Meek Degerud; Simon E Nitter Dankel; Even Fjære et al. (2012). CDKN1A associates with fat regain after weight cycling in mice. (ekstern lenke)
- Simon E Nitter Dankel; Eirik Magnus Meek Degerud; Even Fjære et al. (2012). Candidate genes for fat regain after weight cycling in mice. (ekstern lenke)
Vitenskapelig bokkapittel
- Ellen Færgestad Mosleth; Anette McLeod; Ida Rud et al. (2020). Analysis of Megavariate Data in Functional Omics. (ekstern lenke)
- Odd Terje Brustugun; Gunnar Mellgren; Bjørn Tore Gjertsen et al. (1996). Sensitive and rapid detection of B-galactosidase expression in intact cells by microinjection of fluorecent substrate. (ekstern lenke)
- Line Leonore Haugan Moi; Marianne Hauglid Flågeng; Simon E Nitter Dankel et al. (2011). Steroid Receptor Coactivators and Endocrine Treatment in Breast Cancer. (ekstern lenke)
- Jennifer Gjerde; Line Leonore Haugan Moi; Gunnar Mellgren et al. (2012). Tamoxifen metabolism and biological activity. (ekstern lenke)
- Line Leonore Haugan Moi; Marianne Hauglid Flågeng; Ingvild Sveinsgjerd Fenne et al. (2011). Steroid Receptor Coactivators and Their Expression, Regulation and Functional Role in Endocrine Responsive and Resistant Breast Cancer. (ekstern lenke)
Konferanseabstrakt
- Tuyen Hoang; Simon E Nitter Dankel; Dag Jone Stokke Fadnes et al. (2010). Gene Expression Profile of Nuclear Receptors and Coregulators in Adipose Tissues in Morbid Obesity and after Profound Fat Loss. (ekstern lenke)
- Jennifer Fernandez Gjerde; Marianne Hauglid; Harald Breilid et al. (2007). Effect of CYP2D6 and SULT1A1 genotypes on the serum concentration of 4-hydroxytamoxifen and 4-hydroxy-N-demethyltamoxifen during steady state treatment of breast cancer patients. (ekstern lenke)
- Jennifer Fernandez Gjerde; Jurgen Geisler; Steinar Lundgren et al. (2007). A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment. (ekstern lenke)
- Simon E Nitter Dankel; Dag Jone Stokke Fadnes; Anne-Kristin Stavrum et al. (2010). From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery. (ekstern lenke)
- Jennifer Gjerde; Jürgen Geisler; Steinar Lundgren et al. (2010). Effects of CYP2C19 genotype on tamoxifen and estrogen metabolism. (ekstern lenke)
- Jennifer Fernandez Gjerde; Marianne Hauglid; Harald Breilid et al. (2005). Relationship between CYP2D6 and SULT1A1 genotypes and serum concentrations of tamoxifen and its metabolites during steady state treatment in breast cancer patients. (ekstern lenke)
- Andrea De Censi; Harriet Ann Johansson; Thomas Helland et al. (2020). Relationship between CYP2D6 genotype, tamoxifen metabolites, and adverse events, tumor biomarkers and breast cancer recurrence in a low-dose phase III trial in noninvasive disease. (ekstern lenke)
Masteroppgave
- Oddbjørg Stokkeland; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2013). Effects of Fish Protein and Peptides on Inflammatory Markers and Subjective Joint Pain in Overweight and Obese Adults. (ekstern lenke)
- Marianne Bratlie; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2012). Effects of a high fish intake on leukocyte membrane fatty acid composition and leukocyte function ex vivo in overweight and obese adults. (ekstern lenke)
- Hanne Rosendahl Gjessing; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2010). Impact of Laparoscopic Sleeve Gastrectomy on Body Mass Index, Nutritional Status and Co-morbidity.. (ekstern lenke)
- Kaia Waage; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2013). Effects of Fish Protein and Peptides on Ex Vivo Leukocyte Function and Leukocyte Membrane Fatty Acid Composition in Overweight and Obese Adults. (ekstern lenke)
- Ida Hovland; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2013). Effects of Fish Protein and Peptides on Glucose Tolerance and Leptin:Adiponectin Ratio in Overweight and Obese Adults. (ekstern lenke)
- Anita Helland; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2012). Effects of a high fish intake on glucose tolerance and GLP-1 levels in overweight and obese adults. (ekstern lenke)
- Ingrid Valheim Hagen; Oddrun Anita Gudbrandsen; Gunnar Mellgren (2012). Effects of a high fish intake on lipid and bile acid levels in serum and feces from overweight and obese adults. (ekstern lenke)
- Gunnar Mellgren; Vivian Veum (2009). Fractionation of human adipose tissue using collagenase: gene expression analysis of nuclear receptors (NR) 4A. (ekstern lenke)
- Jørn V. Sagen; Gunnar Mellgren; Simon Dankel (2006). Role of cAMP/PKA in Regulation of GRIP1- and PGC1alpha-Mediated Coactivation of Nuclear Receptor HNF4Alpha. (ekstern lenke)
- Gunnar Mellgren (2008). Nazanin Saemi: Expression and purification of nuclear receptor coactivator GRIP1 deletion mutants. (ekstern lenke)
- Gunnar Mellgren; Nazanin Saemi; Tuyen Hoang (2007). Expression and purification of Nuclear Receptor Coactivator GRIP1 deletion mutants. (ekstern lenke)
- Therese Halvorsen Røst; Rolf Kristian Berge; Gunnar Mellgren (2003). 3-Thia Fatty Acids Inhibit MCF-7 Breast Cancer Cell Proliferation and Induce Ligand Dependent Coactivation of PPARs by p160 Coactivators. (ekstern lenke)
Doktorgradsavhandling
- Linn Anja Slåke Vikøren; Oddrun Anita Gudbrandsen; Jutta Dierkes et al. (2018). Salmon and cod fillet consumption and effects on metabolic risk factors. Intervention studies in humans and rats with overweight and obesity. (ekstern lenke)
- Olivera Bozickovic; Gunnar Mellgren (2015). Regulation and function of steroid receptor coactivator 2 in hepatoma and breast cancer cells. (ekstern lenke)
- Gunnar Mellgren (1996). Hepatocyte growth inhibition by cAMP-dependent protein kinase and other signaling pathways. (ekstern lenke)
- Grethe Åstrøm Ueland; Eystein Sverre Husebye; Paal Methlie et al. (2019). Improved diagnostic workup of hyper- and hypocortisolism. (ekstern lenke)
- Thomas Helland; Gunnar Mellgren (2019). Tamoxifen in the treatment of luminal breast cancer. Implications of active metabolites on gene expression, side effects and clinical outcome. (ekstern lenke)
- Rhian Gaenor Jacobsen; Aurelia Eva Lewis; Gunnar Mellgren (2017). Nuclear phosphoinositide 3-kinase signalling in adipogenesis and the role of DNA topoisomerase IIα as a potential nuclear polyphosphoinositide-binding protein. (ekstern lenke)
- Tuyen Hoang; Gunnar Mellgren; Ernst Asbjørn Lien (2007). Nuclear Receptor Coregulators Role of Protein-Protein Interactions and cAMP/PKA Signaling. (ekstern lenke)
- Line Leonore Haugan Moi; Gunnar Mellgren (2012). Endocrine treatment of breast cancer: Tamoxifen metabolism, steroid receptor coactivators and growth factor receptors. (ekstern lenke)
Populærvitenskapelig artikkel
Vitenskapelig litteraturgjennomgang
- Thomas Helland; Sarah Alsomairy; Chenchia Lin et al. (2021). Generating a precision endoxifen prediction algorithm to advance personalized tamoxifen treatment in patients with breast cancer. (ekstern lenke)
- Simon E Nitter Dankel; Vidar Staalesen; Bodil Bjørndal et al. (2011). Tissue-specific effects of bariatric surgery including mitochondrial function. (ekstern lenke)
- Johan Fernø; Kristina Strand; Gunnar Mellgren et al. (2019). Natural killer cells as sensors of adipose tissue stress. (ekstern lenke)
- Finn Eliassen; Vibeke Iren Jensen Blåfjelldal; Thomas Helland et al. (2023). Importance of endocrine treatment adherence and persistence in breast cancer survivorship: a systematic review. (ekstern lenke)
- Jan-Inge Bjune; Pouda Panahandeh Strømland; Regine Åsen Jersin et al. (2022). Metabolic and Epigenetic Regulation by Estrogen in Adipocytes. (ekstern lenke)
- Johan Lund; Bente Børud; Gunnar Mellgren et al. (2002). Differential regulation of SF-1-cofactor interactions. (ekstern lenke)
Arbeidsnotat
Leserbrev
Forelesning
Se en fullstendig oversikt over publikasjoner i NVA.
Selekterte publikasjoner:
Mellgren, G., Gjertsen, B.T, Otten, A., Maronde, E., Genieser, H-G., Jasdorff, B., Vintermyr, O.K., McKnight, G.S., and Døskeland, S.O. (1995) Novel Rp-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1b action. J. Biol. Chem., 270:20599-20607.
Fladmark, K.E, Brustugun, O.T, Mellgren, G, Krakstad, C, Bøe, R., Vintermyr, O.K., Schulman, H., and Døskeland, S.O. (2002) Ca2+/calmodulin dependent protein kinase II is required for microcystin-induced apoptosis. J. Biol. Chem., 277:2804-2811.
Børud, B., Hoang, T., Bakke, M, Jacob, A., Lund, J, and Mellgren, G (2002). The nuclear coactivators p/CIP and TIF2 differentially regulate PKA-dependent transcriptional activity of Steroidogenic factor-1. Mol. Endocrinol., 16:757-773.
Børud, B., Mellgren, G., Lund, J. and Bakke, M. (2003) Cloning and Characterization of a Novel Zinc-finger Protein that Modulates the Transcriptional Activity of Nuclear Receptors. Mol. Endocrinol., 17:2303-2319
Hoang, T., Fenne, I., Cook, C., Børud, B., Bakke, M., Lien, E.A and Mellgren, G (2004) cAMP-dependent Protein Kinase Regulates Ubiquitin-proteasome mediated Degradation and Subcellular Localization of the Nuclear Receptor Coactivator GRIP1. J. Biol. Chem., 279:49120-49130.
Gjerde, J., Hauglid, M., Breilid, H., Lundgren, S., Varhaug, J.E., Kisanga, E.R., Mellgren, G., Steen, V.M., and Lien, E.A. (2007). Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism. Ann Oncol., 19:56-61.
Fenne, I.S., Hoang, T., Hauglid, M, Sagen, JV, Lien, E.A., and Mellgren, G. (2008). Recruitment of coactivator GRIP1 to an estrogen receptor transcription complex is regulated by cAMP-dependent protein kinase. Endocrinology, 149:4336-45.
Moi, L.H.L., Hauglid, M., Gandini, S, Aliana, G.G., Bonanni, B., Lazzeroni, M., Gjerde, J, Lien, E.A., Decensi, A, and Mellgren G. (2010) Effects of low dose tamoxifen on Steroid Receptor Coactivator 1/Amplified in Breast Cancer 1 in normal an malignant breast tissue. Clin. Cancer Res., 16:2176-86
Dankel SE, Fadnes D, Stavrum AK, Stansberg C, Holdhus R, Hoang T, Veum V, Christensen B, Vaage V, Sagen JV, Steen VM, Mellgren G (2010) Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. PLoS ONE, 9;5(6):e11033
Monika H.E. Christensen, Eva K.R. Pedersen, Yngve Nordbø, Jan Erik Varhaug, Øyvind Midttun, Per M. Ueland, Ottar K. Nygaard, Gunnar Mellgren, Ernst A. Lien (2012) Vitamin B6 Status and Interferon-γ Mediated Immune Activation in Primary Hyperparathyroidism. J Intern Medicine. Jul 3. doi: 10.1111/j.1365-2796.2012.02570.x
Hoang, T. Fenne, I, Johannessen, M, Lien, E.A., Moens, U and Mellgren, G. (2013) cAMP Response Element Binding Protein (CREB) Interacts with the nuclear receptor coactivator GRIP1 and mediates its degradation. Endocrinology,Apr;154(4):1513-27. doi: 10.1210/en.2012-2049. Epub 2013 Mar 5.
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell. 2014 Jan 16;156(1-2):343-58
Ussar S, Lee KY, Dankel SN, Boucher J, Haering MF, Kleinridders A, Thomou T, Xue R, Macotela Y, Cypess AM, Tseng YH, Mellgren G, Kahn CR. ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes. Science Translational Medicine, 2014, 6(247);247ra103.
Aadland EK, Lavigne C, Graff IE, Eng Ø, Paquette M, Holthe A, Mellgren G, Jacques H, Liaset B. Lean-seafood intake reduces cardiovascular lipid risk factors in healthy subjects: results from a randomized controlled trial with a crossover design. Am J Clin Nutr. 2015 Sep;102(3):582-92.
Melina Claussnitzer, Simon Nitter Dankel, Gerald Quon, Kyoung-Han Kim, Wouter Meuleman, Christine Haugen, Viktoria Glunk, Isabel Sousa, Jacqueline L. Beaudry, Vijitha Puviindran, Nezar A. Abdennur, Jannel Liu, Per-Arne Svensson, Yi-Hsiang Hsu, Daniel J. Drucker, Gunnar Mellgren, Chi-Chung Hui, Hans Hauner, Manolis Kellis. FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. New Engl. J. Medicine, 2015 Sep 3;373(10):895-907
Vivian L. Veum, Johnny Laupsa-Borge, Øyvin Eng, Espen Rostrup, Terje H. Larsen, Jan Erik Nordrehaug, Ottar Nygård, Jørn V. Sagen, Oddrun A. Gudbrandsen, Simon N. Dankel, Gunnar Mellgren. Visceral adiposity and metabolic syndrome after very-high-fat and low-fat isocaloric diets: a randomized controlled trial (FATFUNC). Am J Clin Nutr. 2017 Jan;105(1):85-99
Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients. Helland T, Henne N, Bifulco E, Naume B, Borgen E, Kristensen VN, Kvaløy JT, Lash TL, Alnæs GIG, van Schaik RH, Janssen EAM, Hustad S, Lien EA, ‡Mellgren G, ‡Søiland H. Breast Cancer Res. 2017 Nov 28;19(1):125. doi: 10.1186/s13058-017-0916-4.
IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity. Bjune JI, Haugen C, Gudbrandsen O, Nordbø OP, Nielsen HJ, Våge V, Njølstad PR, Sagen JV, Dankel SN, Mellgren G. Int J Obes (Lond). 2019 Nov;43(11):2151-2162
The homeobox factor Irx3 maintains adipogenic identity. Bjune JI, Dyer L, Røsland GV, Tronstad KJ, Njølstad PR, Sagen JV, Dankel SN, Mellgren G. Metabolism. 2019 Nov 18;103:154014. doi: 10.1016/j.metabol.2019.154014.
Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty. Madsen A, Oehme NB, Roelants M, Bruserud IS, Eide GE, Viste K, Bjerknes R, Almås B, Rosendahl K, Sagen JV, Mellgren G, Juliusson PB. J Clin Endocrinol Metab. 2019 Oct 26. pii: dgz094. doi: 10.1210/clinem/dgz094.
3-Hydroxyisobutyrate, A Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism. Nilsen MS, Jersin RÅ, Ulvik A, Madsen A, McCann A, Svensson P-A, Svensson M-E, Nedrebø B-G, Gudbrandsen OA, Tell GS, Kahn CR,Ueland PM, Mellgren G, and Dankel SN. Diabetes 2020; 69:1–14 https://doi.org/10.2337/db19-1174.
Prosjekter
https://www.uib.no/en/rg/hormonelaboratory
Mohn Nutrition Research Laboratory funded by Trond Mohn stiftelse www.uib.no/mohn-elab