Publikasjoner
Vitenskapelig artikkel
- Christiane Helgestad Gjerde; Katrin Kleinmanns; Anika Langer et al. (2026). A 3D ovarian cancer metastasis model using a decellularised peritoneal matrix to study therapy response. (ekstern lenke)
- Tæraneh Jouleh; Spiros Kotopoulis; Georg Dimcevski et al. (2025). Comparison of two- and three-dimensional ultrasound for volume estimation of the meal-stimulated gallbladder. (ekstern lenke)
- Kristoffer Johansen; Torstein Yddal; Spiros Kotopoulis et al. (2014). Acoustic filtering of particles in a flow regime. (ekstern lenke)
- Spiros Kotopoulis; Sabrina Daniela Eder; Martin Møller Greve et al. (2013). Lab-on-a-chip device for fabrication of therapeutic microbubbles on demand. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Chantal Pichon et al. (2012). Real-time sonoporation through HeLa cells. (ekstern lenke)
- Spiros Kotopoulis; Endre Stigen; Mihaela Lucia Popa et al. (2017). Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma. (ekstern lenke)
- Spiros Kotopoulis; Michiel Postema (2010). Microfoam formation in a capillary. (ekstern lenke)
- Asta Kathinka H Retz; Spiros Kotopoulis; Torvid Kiserud et al. (2016). Measured acoustic intensities for clinical diagnostic ultrasound transducers and correlation with thermal index. (ekstern lenke)
- Annemieke van Wamel; Melina Mühlenpfordt; Rune Hansen et al. (2022). Ultrafast Microscopy Imaging of Acoustic Cluster Therapy Bubbles: Activation and Oscillation. (ekstern lenke)
- Tormod Karlsen Bjånes; Spiros Kotopoulis; Elsa Thodesen Murvold et al. (2020). Ultrasound‐ and microbubble‐assisted gemcitabine delivery to pancreatic cancer cells. (ekstern lenke)
- Spiros Kotopoulis; Antje Schommartz; Michiel Postema (2009). Sonic cracking of blue-green algae. (ekstern lenke)
- Spiros Kotopoulis; Han Wang; Sandy Cochran et al. (2010). Lithium niobate ultrasound transducers for high-resolution focused ultrasound surgery. (ekstern lenke)
- Ragnhild Haugse; Anika Langer; Stein-Erik Gullaksen et al. (2019). Intracellular signaling in key pathways is induced by treatment with ultrasound and microbubbles in a leukemia cell line, but not in healthy peripheral blood mononuclear cells. (ekstern lenke)
- Marieke Olsman; Melina Mühlenpfordt; Emma Bøe Olsen et al. (2021). Acoustic Cluster Therapy (ACT®) increases blood-brain barrier permeability and enhances accumulation of core-crosslinked polymeric micelles. (ekstern lenke)
- Spiros Kotopoulis; Antje Schommartz; Michiel Postema (2008). Safety radius for algae eradication at 200 kHz - 2.5 MHz. (ekstern lenke)
- Georg Gjorgji Dimcevski; Spiros Kotopoulis; Tormod Karlsen Bjånes et al. (2016). A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer. (ekstern lenke)
- Tormod Karlsen Bjånes; Lars Petter Jordheim; Jan Schjøtt et al. (2020). Intracellular cytidine deaminase regulates gemcitabine metabolism in pancreatic cancer cell lines. (ekstern lenke)
- Spiros Kotopoulis; Georg Gjorgji Dimcevski; Odd Helge Gilja et al. (2013). Treatment of human pancreatic cancer using combined ultrasound, microbubbles, and gemcitabine: a clinical case study. (ekstern lenke)
- Spiros Kotopoulis; Han Wang; Sandy Cochran et al. (2012). High-frequency transducer for MR-guided FUS. (ekstern lenke)
- Spiros Kotopoulis; Georg Gjorgji Dimcevski; Emmet Mc Cormack et al. (2016). Ultrasound- and microbubble-enhanced chemotherapy for treating pancreatic cancer: A phase I clinical trial. (ekstern lenke)
- Spiros Kotopoulis; Georg Gjorgji Dimcevski; Bjørn Tore Gjertsen et al. (2014). Sonoporation: from the lab to human clinical trials. (ekstern lenke)
- Torstein Yddal; Sandy Cochran; Odd Helge Gilja et al. (2015). Open source, high throughput, ultrasound treatment chamber. (ekstern lenke)
- Spiros Kotopoulis; Ragnhild Haugse; Maja Mujic et al. (2014). Evaluation of the effects of clinical diagnostic ultrasound in combination with ultrasound contrast agents on cell stress: Single cell analysis of intracellular phospho-signaling pathways in blood cancer cells and normal blood leukocytes. (ekstern lenke)
- Torstein Yddal; Spiros Kotopoulis; Odd Helge Gilja et al. (2014). Transparent glass-windowed ultrasound transducers. (ekstern lenke)
- Melina Mühlenpfordt; Emma Bøe Olsen; Spiros Kotopoulis et al. (2023). Real-Time Intravital Imaging of Acoustic Cluster Therapy–Induced Vascular Effects in the Murine Brain. (ekstern lenke)
- Jason Castle; Spiros Kotopoulis; Flemming Forsberg (2020). Sonoporation for augmenting chemotherapy of pancreatic ductal adenocarcinoma. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Albert T. Poortinga et al. (2016). Harmonic antibubbles. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Mihaela Lucia Popa et al. (2014). Sonoporation-enhanced chemotherapy significantly reduces primary tumour burden in an orthotopic pancreatic cancer xenograft. (ekstern lenke)
- Torstein Yddal; Odd Helge Gilja; Sandy Cochran et al. (2016). Glass-windowed ultrasound transducers. (ekstern lenke)
- Kathinka Retz; Spiros Kotopoulis; Torvid Kiserud et al. (2017). Measured acoustic intensities for clinical diagnostic ultrasound transducers and correlation with thermal index. (ekstern lenke)
- Spiros Kotopoulis; Georg Gjorgji Dimcevski; Emmet McCormack et al. (2016). Ultrasound- and microbubble-enhanced chemotherapy for treating pancreatic cancer: a phase I clinical trial. (ekstern lenke)
- Anthony Delalande; Spiros Kotopoulis; Tijs Rovers et al. (2011). Sonoporation at a low mechanical index. (ekstern lenke)
- Nigel Bush; Andrew Healey; Anant Shah et al. (2019). Acoustic Cluster Therapy displays theranostic capability in enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice. (ekstern lenke)
- Nigel Bush; Andrew Healey; Anant Shah et al. (2020). Theranostic attributes of acoustic cluster therapy and its use for enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Michiel Postema (2015). Ultrasonically driven antibubbles encapsulated by Newtonian fluids for active leakage detection. (ekstern lenke)
- Charl Smalberger; Malavika Nathan; David M. Rubin et al. (2022). Experimental setup for the ultrasonic fractionation of flowing whole blood in a capillary. (ekstern lenke)
- Ragnhild Haugse; Anika Langer; Elisa Thodesen Murvold et al. (2020). Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells. (ekstern lenke)
- Spiros Kotopoulis; Christina Lam; Ragnhild Haugse et al. (2022). Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery. (ekstern lenke)
- Ivan Viola; Åsmund Birkeland; Veronika Šoltészová et al. (2013). High-quality 3D visualization of in-situ ultrasonography. (ekstern lenke)
- Spiros Kotopoulis; Mihaela-Lucia Popa; Mireia Mayoral Safont et al. (2022). SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?. (ekstern lenke)
- Spiros Kotopoulis; Kristoffer Johansen; Odd Helge Gilja et al. (2015). Acoustically active antibubbles. (ekstern lenke)
- Christopher W. Schultz; Gorka Ruiz de Garibay; Anika Langer et al. (2021). Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model. (ekstern lenke)
- Bjoern Gerold; Spiros Kotopoulis; Craig McDougall et al. (2011). Laser-nucleated acoustic cavitation in focused ultrasound. (ekstern lenke)
- Charissa Poon; Melina Mühlenpfordt; Marieke Olsman et al. (2022). Real-time intravital multiphoton microscopy to visualize focused ultrasound and microbubble treatments to increase blood-brain barrier permeability. (ekstern lenke)
- Anthony Delalande; Ayache Bouakaz; Gilles Renault et al. (2011). Ultrasound and microbubbles assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype. (ekstern lenke)
- Anthony Delalande; Spiros Kotopoulis; Chantal Pichon et al. (2011). Sonoporation at a low MI. (ekstern lenke)
- Spiros Kotopoulis; Han Wang; Sandy Cochran et al. (2011). Lithium niobate transducers for MRI-guided ultrasonic microsurgery. (ekstern lenke)
- Øystein Solberg Eikrem; Spiros Kotopoulis; Mihaela-Lucia Popa et al. (2021). Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Albert T. Poortinga et al. (2015). Nonlinear echoes from encapsulated antibubbles. (ekstern lenke)
Konferanseposter
- Tæraneh Jouleh; Spiros Kotopoulis; Georg Dimcevski et al. (2024). Gallbladder Volumes Estimated by 2D Versus 3D Ultrasound. (ekstern lenke)
- Tormod Karlsen Bjånes; Lars Petter Jordheim; Jan Schjøtt et al. (2019). Intracellular cytidine deaminase and gemcitabine metabolism in three pancreatic cancer cell lines. (ekstern lenke)
- Tormod Karlsen Bjånes; Jan Schjøtt; Spiros Kotopoulis et al. (2019). Sonoporation and gemcitabine delivery in pancreatic cancer cell lines. (ekstern lenke)
- Tormod Karlsen Bjånes; Lars Petter Jordheim; Jan Schjøtt et al. (2019). role of intracellular cytidine deaminase activity for gemcitabine metabolism in pancreatic cancer cell lines. (ekstern lenke)
- Ragnhild Haugse; Anika Langer; Silje Maria Sundøy et al. (2019). Molecular mechanisms of sonoporation in pancreatic ductal adenocarcinoma (PDAC). (ekstern lenke)
- Karoline Kjellsdotter Søvig; Spiros Kotopoulis; Kim Nylund et al. (2015). Volume estimation of the Gallbladder - 2D vs 3D Ultrasound. (ekstern lenke)
- Tormod Karlsen Bjånes; Lars Petter Jordheim; Jan Schjøtt et al. (2019). Intracellular cytidine deaminase and gemcitabine metabolism in three pancreatic cancer cell lines. (ekstern lenke)
- Tormod Karlsen Bjånes; Elisa Ulvøen Thodesen; Jan Schjøtt et al. (2019). Sonoporation and gemcitabine delivery in pancreatic cell lines. (ekstern lenke)
- Melina Mühlenpfordt; Marieke Olsman; Emma Bøe Olsen et al. (2022). Acoustic Cluster Therapy (ACT®) increases blood-brain barrier permeability and enhances accumulation of core-crosslinked polymeric micelles. (ekstern lenke)
- Elisa Ulvøen Thodesen; Tormod Karlsen Bjånes; Ragnhild Haugse et al. (2019). in vitro optimisation of sonoporation conditions in pancreatic cancer. (ekstern lenke)
- Nigel Bush; Andrew Healey; Anant Shah et al. (2019). Acoustic Cluster Therapy displays theranostic capability in enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice. (ekstern lenke)
Vitenskapelig bokkapittel
- Spiros Kotopoulis; Han Wang; Torstein Yddal et al. (2015). Novel multipurpose, low cost, modular, ultrasound transducers. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Michiel Postema (2015). Active leakage detection by searching for antibubbles. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Chantal Pichon et al. (2012). Biological and medical applications of low-intensity ultrasound. (ekstern lenke)
- Bjoern Gerold; Spiros Kotopoulis; Sandy Cochran et al. (2012). Hybrid laser-ultrasound cavitation for cloud evolution studies. (ekstern lenke)
- Michiel Postema; Spiros Kotopoulis; Klaus-Vitold Jenderka (2012). Basic Principles: Basic physical principles of medical ultrasound. (ekstern lenke)
- Spiros Kotopoulis; Michiel Postema (2010). Forming morphing microfoam. (ekstern lenke)
- Ingrid Kvåle Nordaas; Tæraneh Jouleh; Audun Magerøy trelsgård et al. (2021). Sonoporation in pancreatic cancer (PDAC). (ekstern lenke)
- Maja Mujic; Spiros Kotopoulis; Anthony Delalande et al. (2012). Flow cytometic characterization and sorting of ultrasound contrast agents. (ekstern lenke)
- Anthony Delalande; Spiros Kotopoulis; Patrick Midoux et al. (2012). Ultrasound and microbubble-assisted gene delivery: insights for intracellular mechanism. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Michiel Postema (2015). Ultrasonically driven antibubbles encapsulated by Newtonian fluids for active leakage detection. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Michiel Postema (2015). Introduction to antibubbles. (ekstern lenke)
- Spiros Kotopoulis; Michiel Postema (2013). Using ultrasound to separate oil, gas, and water. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Chantal Pichon et al. (2012). Nonlinear microbubble behaviour for enhanced drug uptake. (ekstern lenke)
- Michiel Postema; Spiros Kotopoulis; Anthony Delalande et al. (2011). Ultrasound-guided delivery and sonoporation. (ekstern lenke)
- Karoline Kjellsdotter Søvig; Spiros Kotopoulis; Kim Nylund et al. (2015). Volume estimation of the Gallbladder - 2D vs 3D Ultrasound. (ekstern lenke)
- Spiros Kotopoulis; Mihaela Lucia Popa; MJ Safont et al. (2015). Sonoporation using Acoustic Cluster Therapy in combination With chemotherapy transiently reduces tumour volume.. (ekstern lenke)
- Spiros Kotopoulis; Kristoffer Johansen; Albert Poortinga et al. (2014). Acoustically active antibubbles for ultrasound imaging and targeted drug delivery. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Chantal Pichon et al. (2011). On cells and sound. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Chantal Pichon et al. (2012). Real-time sonoporation through HeLa cells. (ekstern lenke)
- Spiros Kotopoulis; Michiel Postema (2011). Biomedical ultrasonics, cavitation, and sonoporation. (ekstern lenke)
- Spiros Kotopoulis; Michiel Postema; Sandy Cochran (2011). Ultrasound transducers made with lithium niobate for HF HIFU. (ekstern lenke)
- Anthony Delalande; Spiros Kotopoulis; Patrick Midoux et al. (2011). Cell-microbubble interaction and intracellular fate of plasmid DNA and microbubbles during the sonoporation process. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Chantal Pichon et al. (2012). Sonoporation: using ultrasound for targeted drug delivery. (ekstern lenke)
- Anthony Delalande; Spiros Kotopoulis; Chantal Pichon et al. (2012). Microbubbles and cell interactions. (ekstern lenke)
- Anthony Delalande; Spiros Kotopoulis; Chantal Pichon et al. (2011). Cancer cell sonoporation at low acoustic amplitudes. (ekstern lenke)
- Anthony Delalande; Patrick Midoux; Chantal Pichon et al. (2011). Investigations of microbubble-cell interactions during the sonoporation process. (ekstern lenke)
- Spiros Kotopoulis; Anthony Delalande; Mihaela Popa et al. (2013). Ultrasound and microbubble enhanced therapy of orthotopic human pancreatic cancer in mice. (ekstern lenke)
- Kristoffer Johansen; Spiros Kotopoulis; Albert T. Poortinga et al. (2015). Antibubbles. (ekstern lenke)
- Maja Mujic; Ragnhild Haugse; Spiros Kotopoulis et al. (2013). Ultrasound combined with microbubbles modulates signal transduction pathways in blood cells. (ekstern lenke)
- Georg Gjorgji Dimcevski; Spiros Kotopoulis; Dag Hoem et al. (2013). Ultrasound-assisted treatment of an inoperable pancreatic cancer. (ekstern lenke)
- Spiros Kotopoulis; Ragnhild Haugse; Michiel Postema (2013). Sonoporation: the hurdles that need to be surpassed. (ekstern lenke)
Konferanseabstrakt
- Spiros Kotopoulis; Michiel Postema (2013). High-speed photography of encapsulated microbubbles. (ekstern lenke)
- Georg Gjorgji Dimcevski; Spiros Kotopoulis; Tormod Karlsen Bjånes et al. (2016). Ultrasound and microbubble enhanced treatment of inoperable pancreatic adeonocarcinoma. (ekstern lenke)
- James Posey; Priscilla Machado; John R. Eisenbrey et al. (2023). Sonoporation for disrupting the pancreatic cancer microenvironment to enhance chemotherapy delivery and improve outcomes.. (ekstern lenke)
- Spiros Kotopoulis; Georg Gjorgji Dimcevski; Dag Hoem et al. (2015). Ultrasound sonoporation in pancreatic adenocarcinoma. (ekstern lenke)
- Spiros Kotopoulis; Michiel Postema (2011). Therapeutic ultrasound and sonoporation. (ekstern lenke)
Innledning
Konferanseforedrag
- Spiros Kotopoulis; Mihaela Lucia Popa; MJ Safont et al. (2015). Sonoporation using Acoustic Cluster Therapy in combination With chemotherapy transiently reduces tumour volume.. (ekstern lenke)
- Melina Mühlenpfordt; Emma Bøe Olsen; Spiros Kotopoulis et al. (2022). Real-time intravital imaging of the vascular effects induced by Acoustic Cluster Therapy (ACT®) in a murine brain. (ekstern lenke)
- Nils Kristian Skjaervold; Spiros Kotopoulis; Sverre Løvskar et al. (2023). Oxycate - utvikling av en trådløs engangs cerebral oksygenmonitor for prehospital bruk. (ekstern lenke)
- Melina Mühlenpfordt; Marieke Olsman; Emma Bøe Olsen et al. (2021). Acoustic Cluster Therapy (ACT®) enhances extravasation and parenchymal accumulation of core-crosslinked polymeric micelles in the brain. (ekstern lenke)