My research interests are in the fields of toxicology, environmental toxicology, microplastics, biomarkers, endocrine disruptors, toxicogenomics, environmental genomics, proteomics, and systems toxicology focusing on marine organisms such as fish and marine mammals.

2016-2021: Project leader of "dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua)" (dcod.no), a large interdisciplinary project under the Digital Life Norway network, funded by the BIOTEK 2021 programme of the Research Council of Norway.

2023-2027: Project leader of Marma-detox - Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches, funded by the Research Council of Norway. https://www.digitallifenorway.org/research/marma-detox/index.html

 

BIO 216 Toxicology, BIO 316 Selected topics in environmental toxicology, MOL270 Bioethics

2025

• Helena Costa; Maud Van Essche; Juliane Annemieke Riedel et al. (2025). A whale in a well: Co-exposure of a persistent organic pollutant mixture and cetacean morbillivirus on killer whale (Orcinus orca) primary fibroblasts. (external link)
• Diogo Oliveira; Heli Anna Irmeli Routti; Jenny Bytingsvik et al. (2025). POPs in Barents Sea Marine Mammals: Accumulation vs Biotransformation. (external link)
• Audrey Su; Pierre Blévin; Laura Pirard et al. (2025). From Sea to Lab: Using innovative methods to study large marine mammals. (external link)
• Bram Danneels; Diogo Oliveira; Raquel Ruivo et al. (2025). Evolution of the Chemical Defensome in Marine Mammals. (external link)
• Anders Goksøyr (2025). Whales and Polar bear in a Petri dish: Decoding Marine Mammal Toxicology Through in Vitro and in Silico Approaches. (external link)

1991

• Anders Goksøyr; Håvard E. Larsen (1991). The cytochrome P-450 system of Atlantic salmon (Salmo salar): I. Basal properties and induction of P-450IA1 in liver of immature and mature fish. (external link)
• Anders Goksøyr (1991). A semi-quantitative cytochrome P-450IA1 ELISA: a simple method for studying the monooxygenase induction response in environmental monitoring and ecotoxicological testing of fish. (external link)
• Anders Goksøyr; T. Andersson; D. R. Buhler et al. (1991). Immunochemical cross-reactivity of _b-naphthoflavone-inducible cytochrome P-450 (P-450IA) from different fish species and rat. (external link)
• Anders Goksøyr; Astrid-Mette Husøy; Håvard E. Larsen et al. (1991). Environmental contaminants and biochemical responses in flatfish from the Hvaler Archipelago in Norway. (external link)

2018

• Anders Goksøyr; Guttorm Alendal; Libe Aranguren Abadía et al. (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA). (external link)
• Sofie Sôderstrôm; Anders Goksøyr; Odd Andre Karlsen (2018). Agonistic and antagonistic effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors. (external link)
• Marta Eide; Xiaokang Zhang; Odd Andre Karlsen et al. (2018). MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human. (external link)
• Libe Aranguren-Abadía; Roger Lille-Langøy; Sibel I. Karchner et al. (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.. (external link)

2019

• Carl Henrik Görbitz; Kjetill Sigurd Jakobsen; Simen Rød Sandve et al. (2019). Den sjette masseutryddelse og Jordens DNA. (external link)
• Christine T. Johansen; Siri Øfsthus Goksøyr; Fekadu Yadetie et al. (2019). Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture. (external link)
• Essa Ahsan Khan; Luisa B. Bertotto; Karina Dale et al. (2019). Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. (external link)
• Eileen Marie Hanna; Xiaokang Zhang; Marta Eide et al. (2019). A draft metabolic reconstruction of Atlantic cod (Gadus morhua) liver: how to and what for?. (external link)
• Zhanna Tairova; Mette Helen Bjørge Müller; Sonnich Meier et al. (2019). Biological effects in Atlantic cod (Gadus morhua) and haddock (Melanogrammus aeglefinus) exposed to crude oil with and without UV radiation.. (external link)
• Marta Eide; Xiaokang Zhang; Odd Andre Karlsen et al. (2019). Chemical warfare in the marine environment. (external link)
• Eileen Marie Hanna; Xiaokang Zhang; Shirin Fallahi et al. (2019). A draft metabolic reconstruction of Atlantic cod (Gadus morhua) liver. (external link)
• Marta Eide; Xiaokang Zhang; Odd Andre Karlsen et al. (2019). The chemical defensome of Atlantic cod (Gadus morhua). (external link)
• Pål Asgeir Olsvik; Anett Kristin Larsen; Marc Berntssen et al. (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Conference talk. (external link)
• Heli Anna Irmeli Routti; Mari Katrine Berg; Roger Lille-Langøy et al. (2019). Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA). (external link)
• Siri Øfsthus Goksøyr; Christine T. Johansen; Kristianne Hjort Viken et al. (2019). Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices. (external link)

2020

• Libe Aranguren-Abadía; Roger Lille-Langøy; Alexander Klevedal Madsen et al. (2020). Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. (external link)
• Leah Strople; Anders Goksøyr; Ireen Vieweg (2020). Spawning during an oil spill: how exposure to the water-accommodated fraction of crude oil may disrupt polar cod (Boreogadus saida) reproduction. (external link)
• Fekadu Yadetie; Nadja R Brun; Ireen Vieweg et al. (2020). ANTIESTROGENIC EFFECTS OF BENZO[a]PYRENE REVEALED BY TRANSCRIPTOME ANALYSIS IN POLAR COD LIVER SLICE CULTURE. (external link)
• Katharina Lühmann; Roger Lille-Langøy; Lene Eidsvik Øygarden et al. (2020). Environmental pollutants modulate transcriptional activity of nuclear receptors of whales in vitro. (external link)

1992

• Anders Goksøyr; Jonny Beyer; Håvard E. Larsen et al. (1992). Cytochrome P450 in seals: Monooxygenase activities, immunochemical cross-reactions and response to phenobarbital treatment. (external link)
• Anders Molven; Anders Goksøyr; K. Næss et al. (1992). PAH og klororganiske forbindelser i det marine miljø: oppsummering av forskningsbehov med vekt på norske forhold. Rapport til Forskningsprogram om marin forurensing, NTNF, 1992. (external link)
• R. Stagg; Anders Goksøyr; G. Rodger (1992). Changes in branchial Na, K-ATPase, metallothionein and P450 1A1 in dab (Limanda limanda) in the German Bight. Indicators of sediment contamination?. (external link)

2000

• Augustine Ebeku Arukwe; Anders Goksøyr; Rémi Thibaut et al. (2000). Metabolism and organ distribution of nonylphenol in Atlantic salmon (Salmo salar). (external link)
• Endre Aas; Jonny Beyer; Anders Goksøyr (2000). Fixed wavelength fluorescence (FF) of bile as a monitoring tool for polyaromatic hydrocarbon exposure in fish: an evaluation of compound specificity, inner filter effect and signal interpretation. (external link)
• Vahid Bemanian; Anders Goksøyr; Agneta Rannug et al. (2000). Modulation of Cytochrome P450 1A1, Vitellogenin and Estrogen Receptor Gene Expression by Aryl Hydrocarbon Receptor Ligands in the Fish Liver. (external link)

2022

• Anders Goksøyr; Matthias Kaiser (2022). Hva gjør et rykte om kvikksølv i norsk fisk med sjømatnasjonen?. (external link)
• Lene Frost Andersen; Paula Berstad; Barbara Alexandra Bukhvalova et al. (2022). Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment. (external link)

1999

• Fekadu Yadetie; Augustine Arukwe; Anders Goksøyr et al. (1999). Induction of hepatic estrogen receptor in juvenile Atlantic salmon in vivo by the environmental estrogen 4-nonylphenol. (external link)

2011

• Fekadu Yadetie; Odd Andre Karlsen; Karin Berg et al. (2011). Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.. (external link)
• David Schwesig; Ulrich Borchers; Laure Chancerelle et al. (2011). A harmonized European framework for method validation to support research on emerging pollutants. (external link)

1998

• Augustine Arukwe; Anders Goksøyr (1998). Xenobiotics, xenoestrogens and reproduction distrubances in fish. (external link)
• Anders Goksøyr; Astrid-Mette Husøy (1998). Immunochemical approaches to studies of CYP1A localization and induction by xenobiotics in fish. (external link)

2024

• Sofie Karin Søderstrøm; Pierre Blévin; Audun Håvard Rikardsen et al. (2024). The Marma-detox project ( 2023-2027) “Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches. (external link)
• Jasmine Nahrgang; Claudia Erhart; María Fernández Míguez et al. (2024). Assessing the impact of crude oil on cod fish reproduction: a multi-omics and physiological approach.. (external link)
• Maria Fernandez Miguez; Claudia Erhart; Fekadu Yadetie et al. (2024). Multi-omics assessment of gametogenesis in polar cod exposed to crude oil. (external link)

1987

• Anders Goksøyr (1987). Characterization of the cytochrome P-450 mono-oxygenase system in fish liver : metabolism and effects of organic xenobiotics. (external link)

2002

• Anders Goksøyr (2002). Antibodies against CYP1A proteins used for purification and development of a quantitative CYP1A-ELISA. (external link)
• Anders Goksøyr (2002). Cellene snakker. (external link)
• Jan P. Boon; Jan P. Boon; Jelmer van Zenden et al. (2002). The expression of CYP1A, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses. (external link)
• Manuel J. Rodriguez-Ortega; Christina C. Tolfsen; Bjørn Einar Grøsvik et al. (2002). Protein expression profiles in bivalves exposed to four model environmental pollutants. (external link)

2004

• Bjørn Einar Grøsvik; Anders Goksøyr (2004). Proteomics based methods to study environmental stress in fish and mussels. (external link)
• Anne van Cauwenberge; Luigi Viganò; Anders Goksøyr et al. (2004). In vitro studies with MVLN cells: Effects of water and sediment extracts from the river Lambro, Italy. (external link)
• Anders Goksøyr (2004). Utilizing marine compounds in environmental and food safety diagnostic applications. (external link)
• Anneli Bohne Kjersem; Bjørn Einar Grøsvik; Anders Goksøyr (2004). Proteomics based development of diagnostic methods and monitoring tools for detecting biological effects of oil discharges in fish. (external link)

2016

• Zhanna Tairova; Ian Mayer; Jan Ludvig Lyche et al. (2016). Investigating how toxicants affect population-relevant endpoints in Atlantic cod (Gadus morhua) within the dCod project. (external link)

2001

• Augustine Arukwe; Fekadu Yadetie; Fekadu Yadetie et al. (2001). In vivo modulation of nonylphenol-induced zonagenesis and vitellogenesis. (external link)
• Karin Berg; Mona V. Nilsen; Bernt T. Walther et al. (2001). Monoclonal antibodies against zona radiata proteins for detection of estrogenic effects in fish. (external link)
• Anders Goksøyr (2001). Biotechnology in monitoring the marine environment. (external link)
• Anders Goksøyr (2001). Bioteknologi for et bærekraftig miljø – forskningsbasert forretningsutvikling. (external link)

2003

• Anders Goksøyr (2003). Prospects in non-pharma biotech - developing an industry for environmental monitoring and food safety. (external link)
• Bjørn Einar Grøsvik; Manuel Ortiga Rodriguez; Anders Goksøyr (2003). Crossreactivity of anti-fish CYP1A antibodies to cytoskeletal proteins in bivalves. (external link)

1993

• Jonny Beyer; M. Sandvik; J. U. Skåre et al. (1993). Biomarker responses in marine fish exposed by caging to contaminated fjord sediments. (external link)
• Jonny Beyer; M. Sandvik; J. U. Skåre et al. (1993). Biomarker responses in marine fish exposed by caging to contaminated fjord sediments. (external link)
• Anders Goksøyr; D. O. Oppen-Berntsen (1993). Where to sail in an ocean of opportunities. Proposing a European Laboratory for Molecular Marine Biology in Bergen, Norway. Brosjyre. (external link)

2009

• Anneli Bohne Kjersem; Arnfinn Skadsheim; Anders Goksøyr et al. (2009). Candidate biomarker discovery in plasma of juvenile cod (Gadus morhua) exposed to crude North Sea oil, alkyl phenols and polycyclic aromatic hydrocarbons (PAHs). (external link)

2007

• Marianne Brattås; Silje Tingstad; Amund Maage et al. (2007). Biomarker responses in juvenile Atlantic cod (Gadus morhua) exposed to Hg- and PAH/PCB-polluted sediments. (external link)
• Christina C Tolfsen; Tina Søfteland; Ralph Urbatzka et al. (2007). Application of proteomics for protein expression profiling and biomarker discovery. (external link)
• Ole Jakob Nøstbakken; Bjarte Hesjevoll; Vahid Bemanian et al. (2007). Dioxin-induced protein-protein interactions between the aryl hydrocarbon receptor and the aryl hydrocarbon nuclear translocator from Atlantic salmon (Salmo salar). (external link)
• Bjørn Einar Grøsvik; Sonnich Meier; Karen Anita Aa et al. (2007). Biomarker levels and toxicoproteomics in Atlantic cod exposed to produced water and estradiol during early life stages. (external link)
• Anders Goksøyr (2007). Overvåking av toksiske effekter i havet: Utvikling av nye metofer basert på biomarkører. (external link)
• Anneli Bohne Kjersem; Karen Anita Aa; Sonnich Meier et al. (2007). A proteomic based approach for developing new biomarkers as tools for biological effects of oil and produced water. (external link)
• Anders Goksøyr; Christina C Tolfsen; Tina Søfteland et al. (2007). Vitellogenin profiling in liver, plasma and mucus of carp (Cyprinus carpio) exposed to endocrine disrupting chemicals: New facets of an old biomarker gem. (external link)

2017

• Karina Dale; Odd Andre Karlsen; Fekadu Yadetie et al. (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway. (external link)
• Anders Goksøyr (2017). Cod as canaries - and polar bear in a Petri dish. (external link)
• Anders Goksøyr (2017). Cod as canaries - and polar bear in a Petri dish. Explorations in ecotoxicology. (external link)
• Anders Goksøyr (2017). From cod to polar bear: Toxicogenomics and ecotoxicology. (external link)
• Karina Dale; Anders Goksøyr; Odd Andre Karlsen et al. (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway. (external link)
• Siri Øfsthus Goksøyr; Fekadu Yadetie; Marta Eide et al. (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors. (external link)
• Shirin Fallahi; Rune Kleppe; Anders Goksøyr et al. (2017). Mathematical modeling of regulatory interactions in the fatty acid synthesis pathway. (external link)

1997

• Anders Goksøyr (1997). Har vi tilfressstillende metoder for å overvåke biologiske effekter av forurensning?. (external link)
• Morten Sandvik; Jonny Beyer; Anders Goksøyr et al. (1997). Interactive effects of benzo(a)pyrene, 2.3.3´,4,4´,5-hexachlorobiphenyl (PCB-156) and cadmium on biomarker responses in flounder (Platichthys flesu. (external link)
• Anders Goksøyr; Jonny Beyer; Eliann Egaas et al. (1997). Biomarker responses in flounder (Platichthys flesus) and their use in pollution monitoring. (external link)
• Augustine Arukve; F.R Knudsen; Anders Goksøyr (1997). Fish zona radiata (eggshell) protein: A sensitive biomarker for environmental estrogens. (external link)
• Jonny Beyer; Morten Sandvik; Janneche Utne Skåre et al. (1997). Time- and dose-dependent biomarker responses in flounder (Platichthys flesus) exposed to benzo(a)pyrene, 2,3,3´,4,4´,5-hexachlorobiphenyl (PCB-156) and cadmium. (external link)

2015

• Øyvind Paasche; Henrik Österblom; Stefan Neuenfeldt et al. (2015). Connecting the seas of Norden. (external link)

2005

• Tina Søfteland; Christina Charlotte Tolfsen; Luigi Viganò et al. (2005). Proteomic analysis of liver from ethinylestradiol (EE2) and tamoxifen exposed common carp (Cyprinus carpio L.) and African clawed frog (Xenopus laevis). (external link)
• Lilian Viveka Sundback; Christina Charlotte Tolfsen; Luigi Viganò et al. (2005). Proteome studies of plasma from common carp (Cyprinus carpio L.) exposed to 17 α-ethinylestradiol. (external link)

2012

• Marta Eide; Odd Andre Karlsen; Pål Asgeir Olsvik et al. (2012). Integrative environmental genomics of Atlantic cod (Gadus morhua): exposure of cod liver slices to environmental contaminants. (external link)

2021

• Anders Goksøyr (2021). U-864: Heving eller tildekking. (external link)
• Roger Lille-Langøy; Kåre Bredeli Jørgensen; Anders Goksøyr et al. (2021). Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. (external link)
• Heli Anna Irmeli Routti; Mikael Harju; Katharina Lühmann et al. (2021). Concentrations and endocrine disruptive potential of phthalates in marine mammals from the Norwegian Arctic. (external link)
• Marta Eide; Xiaokang Zhang; Odd André Karlsen et al. (2021). The chemical defensome of five model teleost fish. (external link)

2010

• Gaëlle Marteil; Romain D'Inca; Aude Pascal et al. (2010). EP45 accumulates in growing Xenopus laevis oocytes and has oocyte-maturation-enhancing activity involved in oocyte quality. (external link)

2023

• J. Bjørneset; P. Blévin; P.M. Bjørnstad et al. (2023). Establishment of killer whale (Orcinus orca) primary fibroblast cell cultures and their transcriptomic responses to pollutant exposure. (external link)

2006

• Anders Goksøyr (2006). Hormonforstyrrende stoffer i miljøet - hva er det som skjer?. (external link)
• Anders Goksøyr (2006). PCB og dioksiner i maten: Nye verktøy for risikovurdering. (external link)
• Syed A.M. Al-Arabi; J. U. Skaare; Ketil Hylland et al. (2006). Contaminant accumulation and biomarker responses in sharptooth catfish (Clarias gariepinus) cultured in three different ponds (sewage wastewater and-fed, tannery wastewater-fed laden and control) ponds. (external link)
• Bjørn Einar Grøsvik; Anneli Bohne Kjersem; R Sundt et al. (2006). Effects of oil and produced water on Atlantic cod; biomarker development with proteomics based methods. (external link)
• Bjørn Einar Grøsvik; Christina C Tolfsen; Anders Goksøyr (2006). Studies of protein pattern in digestive gland of blue mussel (Mytilus edulis) deployed in cages in vicinity of the Statfjord oil field. (external link)

1995

• H. M. Sleiderink; J. M. Everaarts; Anders Goksøyr et al. (1995). Hepatic cytochrome P4501A induction in DAB (Limanda limanda) after oral dosing with the polychlorinated biphenyl mixture Clophen A40. (external link)

2013

• Alfonso C.D. Bainy; Akira Kubota; Jared V. Goldstone et al. (2013). Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio). (external link)

See a complete overview of publications in NVA.

http://publicationslist.org/anders.goksoyr

Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches

https://www.digitallifenorway.org/research/marma-detox/index.html