Toksikologi, miljøtoksikologi, biomarkører, hormonforstyrrende stoffer, toksikogenomikk, miljøgenomikk, proteomikk, mikroplast, fisk, sjøpattedyr

BIO 316 - Utvalgte emner i miljøtoksikologi, MOL270 - Bioetikk

2026

• María Fernández Míguez; Odd André Karlsen; Jasmine Nahrgang et al. (2026). The overlooked role of the resin fraction: mechanistic insights into WAF crude oil toxicity with ex vivo and in vitro techniques. (ekstern lenke)

2025

• Anders Goksøyr; Lene Liebe Delsett; Rein Aasland (2025). På sporet av moderne biologi i Museets samlinger. (ekstern lenke)
• Helena Costa; Maud Van Essche; Juliane Annemieke Riedel et al. (2025). A whale in a well: Co-exposure of a persistent organic pollutant mixture and cetacean morbillivirus on killer whale (Orcinus orca) primary fibroblasts. (ekstern lenke)
• Bram Danneels; Diogo Oliveira; Raquel Ruivo et al. (2025). Evolution of the Chemical Defensome in Mammals. (ekstern lenke)
• Franco, Marco E; Araújo, Cristiano V M; Cerveny, Daniel et al. (2025). Extended chemical defensome: emphasizing mechanisms of defense as key research avenues to tackle priority questions in environmental toxicology. (ekstern lenke)
• Sofie Søderstrøm; Anya Mukundan; Sara Zamani et al. (2025). Marma-detox: Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches. (ekstern lenke)
• Diogo Oliveira; Heli Anna Irmeli Routti; Jenny Bytingsvik et al. (2025). POPs in Barents Sea Marine Mammals: Accumulation vs Biotransformation. (ekstern lenke)
• Odd André Karlsen; Cecilie F. Vidme; Rhian Gaenor Jacobsen et al. (2025). Development of a cell-free new approach methodology (NAM) for assessment of xenoestrogenic compounds in a non-model teleost species. (ekstern lenke)
• Odd André Karlsen; Rhian Gaenor Jacobsen; Fekadu Yadetie et al. (2025). Development of an Atlantic Cod (Gadus morhua) Estrogen Receptor TR-FRET Assay for Assessment of Xenoestrogens in a Non-model Teleost Species. (ekstern lenke)
• Elisa P. Pereira; Nadja Rebecca Brun; Rhian Gaenor Jacobsen et al. (2025). MODULATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPARA) ACTIVITY IN ZEBRAFISH (DANIO RERIO ) BY LEGACY AND EMERGING PERFLUOROALKYL SUBSTANCES (PFAS). (ekstern lenke)
• Cecilie F. Vidme; Rhian Gaenor Jacobsen; Fekadu Yadetie et al. (2025). Development of estrogen receptor TR-FRET assays for assessment of estrogenic effects of bisphenol compounds. (ekstern lenke)
• Robert Franz Wild; Anders Goksøyr; Odd André Karlsen et al. (2025). Computational Predictions of the Binding Activity of Endocrine Disrupting Compounds to the Estrogen Receptor Alpha: Evaluation of the applicability of molecular docking and simulations. (ekstern lenke)
• Audrey Su; Pierre Blévin; Anders Goksøyr (2025). From Sea to Lab - Using innovative methods to study large marine mammals. (ekstern lenke)
• Audrey su; Eve Marie Jourdain; Clare Margaret Andvik et al. (2025). Den forgiftede hvalen Elida. (ekstern lenke)
• audrey su; Pierre Blévin; Anders Goksøyr (2025). From Sea to Lab - Using innovative methods to study large marine mammals. (ekstern lenke)
• Audrey Su; Pierre Blévin; Laura Pirard et al. (2025). From Sea to Lab: Using innovative methods to study large marine mammals. (ekstern lenke)
• maud van essche; Anders Goksøyr; Audun H. Rikardsen et al. (2025). Marine mammals and polar bears in a petri dish: Cell isolation, differentiation, and exposure experiments for pollution impact assessment. (ekstern lenke)
• Laura Pirard; Pierre Blévin; Fekadu Yadetie et al. (2025). Polar bears on thin ice: effects of sea-ice decline and pollutants on plasma lipidome and adipose tissue transcriptome. (ekstern lenke)
• Anders Goksøyr; Audrey Su; Rakel Odette Tetlie et al. (2025). Elida - den forgiftede hvalen. (ekstern lenke)
• Malin Birkeland ; Jasmine Nahrgang; Odd André Karlsen et al. (2025). Using precision-cut liver slices for assessing hepatic toxicity of components of crude oil on Atlantic cod. (ekstern lenke)
• Maria Fernandez Miguez; Lenny Debuck; R Cremer et al. (2025). MULTI-OMICS AND BIOMARKER ASSESSMENT OF REPRODUCTIVE TOXICITY IN POLAR COD (BOREOGADUS SAIDA) EXPOSED TO CRUDE OIL. (ekstern lenke)
• Maria Fernandez Miguez; Malin Birkeland; Aliza Naeem Rana et al. (2025). Fish to flask: Advancing crude oil toxicity testing with ex vivo and in vitro techniques. (ekstern lenke)
• Bram Danneels; Diogo Oliveira; Raquel Ruivo et al. (2025). Evolution of the Chemical Defensome in Marine Mammals. (ekstern lenke)
• Malin Stamnes Birkeland; Anders Goksøyr; Odd André Karlsen et al. (2025). Assessing toxicity of crude oil water accommodated fractions and sub-fractions using Atlantic cod (Gadus morhua) precision cut liver slices. (ekstern lenke)
• Cecilie Farstad Vidme; Odd André Karlsen; Anders Goksøyr (2025). Development of Estrogen Receptor Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assays for Assessing the Estrogenic Effects of Bisphenol Compounds. (ekstern lenke)

2024

• Sofie Søderstrøm; Pierre Blévin; Audun H. Rikardsen et al. (2024). Marma-detox Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches. (ekstern lenke)

2018

• Xiaokang Zhang; Marta Eide; Odd Andre Karlsen et al. (2018). Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human. (ekstern lenke)
• Marta Eide; Xiaokang Zhang; Odd Andre Karlsen et al. (2018). Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans. (ekstern lenke)
• Karina Dale; Odd Andre Karlsen; Fekadu Yadetie et al. (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway. (ekstern lenke)
• Karina Dale; Odd Andre Karlsen; Fekadu Yadetie et al. (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway. (ekstern lenke)
• Anders Goksøyr; Guttorm Alendal; Libe Aranguren Abadía et al. (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA). (ekstern lenke)

2023

• Chukwuebuka ThankGod Eze; Adebayo Akeem Otitoloju; Obianuju Oluchukwu Eze et al. (2023). West African e-waste-soil assessed with a battery of cell-based bioassays. (ekstern lenke)

2017

• Fekadu Yadetie; Eystein Oveland; Anne Marie Simonne Døskeland et al. (2017). Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. (ekstern lenke)

2001

• Anders Goksøyr (2001). DNA - den mystiska arvsmassan. (ekstern lenke)
• Karin Berg; Kjersti Bringsvor; Mona V. Nilsen et al. (2001). Monoclonal antibodies against zona radiata proteins for detection of estrogenic effects in fish. (ekstern lenke)
• Bente M. Nilsen; Janne K. Eidem; Sven Inge Kristiansen et al. (2001). Development of quantitative vitellogenin ELISA assays for fish test species used in endocrine disruptor screening. (ekstern lenke)

1991

• Anders Goksøyr; T. S. Solberg; B. Serigstad (1991). Immunochemical detection of cytochrome P-450IA1 induction in cod (Gadus morhua) larvae and juveniles exposed to a water soluble fraction of North S crude Oil. (ekstern lenke)
• E. Gram Jensen; J. U. Skaare; E. Egaas et al. (1991). Response of xenobiotic metabolizing enzymes in rainbow trout (Oncorhynchus mykiss) to endosulfan, detected by enzyme activities and immunochemical methods. (ekstern lenke)
• Anders Goksøyr; Håvard E. Larsen (1991). The cytochrome P-450 system of Atlantic salmon (Salmo salar): I. Basal properties and induction of P-450IA1 in liver of immature and mature fish. (ekstern lenke)
• Anders Goksøyr; Håvard E. Larsen; Astrid-Mette Husøy (1991). Application of cytochrome P-450IA1 ELISA in environmental monitoring and ecotoxicological testing of fish. (ekstern lenke)
• Y. Zhang; Anders Goksøyr; T. Andersson et al. (1991). Initial purification and characterization of hepatic microsomal cytochrome P-450 from BNF-treated perch (Perca fluviatilis). (ekstern lenke)
• Anders Goksøyr (1991). A semi-quantitative cytochrome P-450IA1 ELISA: a simple method for studying the monooxygenase induction response in environmental monitoring and ecotoxicological testing of fish. (ekstern lenke)
• Anders Goksøyr; T. Andersson; D. R. Buhler et al. (1991). Immunochemical cross-reactivity of _b-naphthoflavone-inducible cytochrome P-450 (P-450IA) from different fish species and rat. (ekstern lenke)
• Anders Goksøyr; Astrid-Mette Husøy; Håvard E. Larsen et al. (1991). Environmental contaminants and biochemical responses in flatfish from the Hvaler Archipelago in Norway. (ekstern lenke)
• J. Utne Skaare; Anders Goksøyr; E. Egaas et al. (1991). Response of xenobiotic metabolizing enzymes of rainbow trout to the mono-ortho substituted polychlorinated PCB congener 2,3',4,4',5-pentachlorobiphenyl, PCB-118, detected by enzyme activities and immunochemical methods. (ekstern lenke)

1992

• M. E. J. van der Weiden; M. Celander; W. Seinen et al. (1992). The use of immunochemical determination of cytochrome P450 1A1 orthologue and EROD activity assay in rainbow trout and carp, treated with 2,3,7,8,-TCDD or exposed to contaminated sediment. (ekstern lenke)
• E. Egaas; J. U. Skaare; Anders Goksøyr et al. (1992). Effect of the insecticide Thiodan 35 (endosulfan) on xenobiotic metabolizing enzymes from midgut and gut-free tissues of some coleoptrean larva. (ekstern lenke)
• Anders Goksøyr; Håvard E. Larsen; S. Blom et al. (1992). Detection of cytochrom P450 in North Sea dab liver and kidney. (ekstern lenke)
• J. P. Boon; J. M. Everaarts; M. T. Hillebrand et al. (1992). Changes in levels of hepatic biotransformation enzymes and haemoglobin levels in female plaice (Pleuronectes platessa) a. (ekstern lenke)
• Anders Goksøyr; Jonny Beyer; Håvard E. Larsen et al. (1992). Cytochrome P450 in seals: Monooxygenase activities, immunochemical cross-reactions and response to phenobarbital treatment. (ekstern lenke)
• Anders Goksøyr; L. Førlin (1992). The cytochrome P450 system in fish, aquatic toxicology and environmental monitoring. (ekstern lenke)
• Håvard E. Larsen; M. Celander; Anders Goksøyr (1992). The cytochrome P450 system of Atlantic salmon (Salmo salar): 2. Variations in catalytic activities and isozyme patterns during an annual reproductive cycle. (ekstern lenke)
• M. Pesonen; Anders Goksøyr; T. Andersson (1992). Expression of P450 1A1 in a primary culture of rainbow trout hepatocytes exposed to _b-naphthoflavone or 2,3,7,8-tetrachlorodibenzo-p-dioxin. (ekstern lenke)
• Anders Goksøyr; Astrid-Mette Husøy (1992). The cytochrome P450 1A1 response in fish: application of immunodetection in environmental monitoring and toxicological testing. (ekstern lenke)
• T. K. Collier; D. Connor; B.-T. Eberhart et al. (1992). Using cytochrome P450 to monotoring the aquatic environment: results from regional and national surveys. (ekstern lenke)

2011

• Karin Berg; Pål Puntervoll; Jarle Klungsøyr et al. (2011). Brain proteome alterations of Atlantic cod (Gadus morhua) exposed to PCB 153. (ekstern lenke)
• Fekadu Yadetie; Odd Andre Karlsen; Karin Berg et al. (2011). Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.. (ekstern lenke)

2014

• Marianne Brattås; Odd Andre Karlsen; Anders Goksøyr et al. (2014). Alterations in the hepatic proteome of polar cod (Boreogadus saida) after dietary exposure to benzo(a)pyrene. (ekstern lenke)
• Marianne Brattås; Odd Andre Karlsen; Anders Goksøyr et al. (2014). ALTERATIONS IN THE HEPATIC PROTEOME OF POLAR COD (BOREOGADUS SAIDA) AFTER DIETARY EXPOSURE TO BENZO[A]PYRENE. (ekstern lenke)

2021

• Anders Goksøyr; Siri Øfsthus Goksøyr; Fekadu Yadetie et al. (2021). Development of a battery of Atlantic cod receptor-based reporter bioassays for assessing environmental toxicity of sediments and chemicals. (ekstern lenke)
• Anders Goksøyr (2021). Hunnsnegl med penis og hannfisk med egg. (ekstern lenke)

1997

• Bjørn Einar Grøsvik; Ø Vågenes; Bo Holmqvist et al. (1997). Cytochrome P4501A protein expression and localisation in primary cultures of atrial endothelial cells from fish. (ekstern lenke)
• Sven-Inge Kristiansen; Åse Ingvill Berge; Anders Goksøyr (1997). Changes in salmon (Salmo salar) cytochrome P450 system and induction response during smoltification. (ekstern lenke)
• J.J. Stegeman; C.A. Miller; Jonny Beyer et al. (1997). Cytochrome P4501A expression and localization in organs of the Minke Whale (Balaenoptera acutorostrata). (ekstern lenke)
• C Van Hezik; J. Hedman; K. Ingebrigtsen et al. (1997). CYP 1A-induction in Atlantic Cod (Gadus morhua) after aqueous exposure to benzo(a)pyrene. (ekstern lenke)
• S.H.N.P. Gunawickrama; Anders Goksøyr (1997). Effects of long-term toxicant exposure on selected molecular biomarkers, liver histopathology, genotoxicity and reproductive toxicology of turbot, Scophthalmus maximus). (ekstern lenke)
• Rune Male; Dag O. Oppen-Berntsen; Augustine Arukwe et al. (1997). Zona pellucida proteins, possible new markers for environmental estrogens. (ekstern lenke)
• Ingunn Myhre; Bjørn Einar Grøsvik; Anders Goksøyr (1997). Induction of CYP1A in primary cultures of hepatocytes from Atlantic Salmon (Salmo salar) by benzo(a)pyrene and polychlorinated biphenyl. (ekstern lenke)
• Lars Petter Myhre; Anders Goksøyr (1997). Induction of biomarkers in Eel (Anguilla anguilla) by environmental pollutants in laboratory and field studies in Western Norway. (ekstern lenke)
• Eliann Egaas; Anders Goksøyr; E. Fjell et al. (1997). Some effects of a fungicide on cytochrome P450 and glutathione S-transferase in fish. (ekstern lenke)
• S.A.M. Al-Arabi; Anders Goksøyr (1997). Species characteristics of hepatic biotransformation enzymes in two tropical fish of Bangladesh, One Riverine Catfish (Rita rita) and One Marine Mudskipper (Apocryptes bato). (ekstern lenke)

2020

• Leah Strople; Ireen Vieweg; Fekadu Yadetie et al. (2020). Polar cod and Goliat: How an oil spill may affect polar cod reproduction. (ekstern lenke)
• Essa Ahsan Khan; Xiaokang Zhang; Eileen Marie Hanna et al. (2020). Quantitative transcriptomics, and lipidomics in evaluating ovarian developmental effects in Atlantic cod (Gadus morhua) caged at a capped marine waste disposal site. (ekstern lenke)
• Libe Aranguren-Abadía; Roger Lille-Langøy; Alexander Klevedal Madsen et al. (2020). Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. (ekstern lenke)
• Marta Eide; Anders Goksøyr; Fekadu Yadetie et al. (2020). A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua). (ekstern lenke)

2000

• Augustine Ebeku Arukwe; Trine Celius; Bernt T. Walther et al. (2000). Effects of xenoestrogen treatment on zona radiata protein and vitellogenin expression in Atlantic salmon (Salmo salar). (ekstern lenke)
• Rune Male; Fekadu Yadetie; Anders Goksøyr (2000). Effects of the environmental estrogen 4- nonylphenol on the expression of selected genes in Atlantic salmon pituitary, liver and gonads. (ekstern lenke)
• Augustine Ebeku Arukwe; Anders Goksøyr; Rémi Thibaut et al. (2000). Metabolism and organ distribution of nonylphenol in Atlantic salmon (Salmo salar). (ekstern lenke)
• Endre Aas; Jonny Beyer; Anders Goksøyr (2000). Fixed wavelength fluorescence (FF) of bile as a monitoring tool for polyaromatic hydrocarbon exposure in fish: an evaluation of compound specificity, inner filter effect and signal interpretation. (ekstern lenke)

2019

• Carl Henrik Görbitz; Kjetill Sigurd Jakobsen; Simen Rød Sandve et al. (2019). Den sjette masseutryddelse og Jordens DNA. (ekstern lenke)
• Christine T. Johansen; Siri Øfsthus Goksøyr; Fekadu Yadetie et al. (2019). In vitro assessment of estrogenic effects of bisphenols on Atlantic cod (Gadus morhua). (ekstern lenke)
• Siri Øfsthus Goksøyr; Christine T. Johansen; Kristianne Hjort Viken et al. (2019). In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua). (ekstern lenke)
• Pål Asgeir Olsvik; Anett Kristin Larsen; Marc Berntssen et al. (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. (ekstern lenke)
• Christine T. Johansen; Siri Øfsthus Goksøyr; Fekadu Yadetie et al. (2019). Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture. (ekstern lenke)
• Siri Øfsthus Goksøyr; Elisabeth Ueland; Roger Lille-Langøy et al. (2019). Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua). (ekstern lenke)
• Anders Goksøyr (2019). Se torsken! Om torsk, miljøgifter og torskens genom.. (ekstern lenke)
• Essa Ahsan Khan; Luisa B. Bertotto; Karina Dale et al. (2019). Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. (ekstern lenke)
• Anders Goksøyr; Guttorm Alendal; Libe Aranguren-Abadía et al. (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR. (ekstern lenke)
• Anders Goksøyr; Guttorm Alendal; Libe Aranguren-Abadía et al. (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR. (ekstern lenke)

2006

• Henrik Jonsson; Doris Schiedek; Bjørn Einar Grøsvik et al. (2006). Protein responses in blue mussels (Mytilus edulis) exposed to organic pollutants: A combined CYP-antibody/proteomic approach. (ekstern lenke)
• Bjørn Einar Grøsvik; Henrik Jonsson; Manuel J. Rodriguez-Ortega et al. (2006). CYP1A-immunopositive proteins in bivalves identified as cytoskeletal and major vault proteins. (ekstern lenke)
• Anders Goksøyr (2006). Endocrine disruptors in the marine environment: Mechanisms of toxicity and their influence on reproductive processes in fish. (ekstern lenke)

2022

• Benuarda Toto; Alice Refosco; Maria O'Keeffe et al. (2022). Intestinal permeability and gene expression after polyethylene and polyamide microplastic ingestion in Wistar rats. (ekstern lenke)
• Anne Hareide Lund; Fekadu Yadetie; Odd André Karlsen et al. (2022). Using fin whale fibroblasts in toxicological studies. (ekstern lenke)
• Sofie Karin Söderström; Roger Lille-Langøy; Fekadu Yadetie et al. (2022). Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). (ekstern lenke)
• Anders Goksøyr; Matthias Kaiser (2022). Hva gjør et rykte om kvikksølv i norsk fisk med sjømatnasjonen?. (ekstern lenke)
• Juni Bjørneset; Pierre Blévin; Pål Marius Bjørnstad et al. (2022). Establishment of killer whale cell cultures and their transcriptome responses to pollutant exposure. (ekstern lenke)

1996

• Ketil Hylland; Morten Sandvik; Janneche Utne Skaare et al. (1996). Biomarkers in flounder (Platichthys flesus): An evaluation of their use in pollution monitoring. (ekstern lenke)

1999

• Fekadu Yadetie; Augustine Arukwe; Anders Goksøyr et al. (1999). Induction of hepatic estrogen receptor in juvenile Atlantic salmon in vivo by the environmental estrogen 4-nonylphenol. (ekstern lenke)

2004

• Magnus Blø; Bjørn Einar Grøsvik; Anders Goksøyr (2004). Proteombaserte studier av differensiell proteinekspresjon i laks (Salmo salar L.) eksponert for miljøgifter; in vitro og in vivo studier. (ekstern lenke)

Se en fullstendig oversikt over publikasjoner i NVA.

Cristin

2016-2012: dCod 1.0: decoding systems toxicology of Atlantic cod (Gadus morhua), tilknyttet Senter for Digitalt Liv Norge, se http://www.dcod.no

2023-2027: Marma-detox - Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches

https://www.digitallifenorway.org/research/marma-detox/index.html