Pediatric Follow-up Group

The overall objective of the research group is clinical research on health and developement in children at risk and medical care of diseased children.

Affiliation

About the research group

Research areas are pediatric interventions, short- and long-term outcome related to fetal and neonatal period, growth, organ function and general development in the young. Research methods include follow-up of cohorts, clinical trials and register based studies.

The group cooperates closely with the Department of Pediatrics at Haukeland University Hospital and Stavanger University Hospital as well as Helse Fonna and Helse Førde and most group members are both clinical physicians and researchers within pediatric health care. In addition there is broad cooperation with other research groups locally as well as nationally and internationally. 

The coordinator of the group is professor Camilla Tøndel. 

Relevant links

Projects

Innovative Therapies for Children

The Pediatric Clinical Trials Unit at Haukeland University Hospital was established in 2007 as the first of its kind in Northern Europe and has a large track record on running pediatric clinical trials (Phase I-IV). At Stavanger University Hospital the Pediatric Clinical Trials Unit was established in 2018. There is a broad collaboration both with the industry and international academic milieus. Several of the trials are funded from EU: Incentive and Vaccelerate.

NorPedMed is a national network to increase clinical drug trials for children and has been funded by Norwegian Government since 2013. NorPedMed is partner in the EU-funded PedCRIN “The Paediatric Clinical Research Infrastructure Network” and Conect4Children “Collaborative Network for European Clinical Trials for Children” as well as part of NordicPedMed funded by Nordic Council since 2015.

NorCRIN was established as the Norwegian branch of ECRIN in 2012 and has been funded from Norwegian Research Counsel since 2015. The secretariat of NorCRIN and NorPedMed are both placed in Bergen and collaborate well to increase clinical studies in Norway.

 

Norwegian media outlets: 

  1. Vaksine mot vannkopper (NRK Dagsnytt 18)
  2. Foreslår at alle barn skal få vaksine mot vannkopper fra neste år (NRK.no)
  3. Evolving screening and diagnosis strategies in Fabry disease (Rare Revolution Magazine)
  4. Bør alle norske barn vaksineres mot vannkopper? (Forskning.no)
  5. GMO-regler må ikke få stoppe utviklingen av avanserte terapier (dagensmedisin.no)
  6. NOU 2023: 18 Genteknologi i en bærekraftig fremtid (regjeringen.no)
  7. Katrine (47) har meldt seg frivillig til å teste en ny, norsk vaksine. Håpet er at den skal beskytte lenger enn de man har hatt til nå. (bt.no)
  8. Mulig ny behandling mot Fabry sykdom kan gi sjeldnere intravenøs behandling (dagensmedisin.no)
  9. Har testet medisiner på 400 barn – NRK Vestland
  10. – De tre første månedene var verst (ba.no)
  11. Forskning på legemidler til barn må gjøres i Norge! – Paidos

 

Peer review publications:

  1. Keating C, Yonker LM, Vermeulen F, Prais D, Linnemann RW, Trimble A, Kotsimbos T,Mermis J, Braun AT, O'Carroll M, Sutharsan S, Ramsey B, Mall MA, Taylor-Cousar JL, McKone EF, Tullis E, Floreth T, Michelson P, Sosnay PR, Nair N, Zahigian R, Martin H, Ahluwalia N, Lam A, Horsley A; VX20-121-102 Study Group; VX20-121-103 Study Group. Vanzacaftor-tezacaftor-deutivacaftor versus elexacaftor-tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years and older (SKYLINE Trials VX20-121-102 and VX20-121-103): results from two randomised, active-controlled, phase 3 trials. Lancet Respir Med. 2025 Mar;13(3):256-271. doi: 10.1016/S2213-2600(24)00411-9. Epub 2025 Jan 2. Erratum in: Lancet Respir Med. 2025 Mar;13(3):e19. doi: 10.1016/S2213-2600(25)00011-6. PMID: 39756424.
  2. Holida M, Linhart A, Pisani A, Longo N, Eyskens F, Goker-Alpan O, Wallace E, Deegan P, Tøndel C, Feldt-Rasmussen U, Hughes D, Sakov A, Rocco R, Almon EB, Alon S, Chertkoff R, Warnock DG, Waldek S, Wilcox WR, Bernat JA. A phase III, open-label clinical trial evaluating pegunigalsidase alfa administered every 4 weeks in adults with Fabry disease previously treated with other enzyme replacement therapies. J Inherit Metab Dis. 2025 Jan;48(1):e12795. doi: 10.1002/jimd.12795. Epub 2024 Oct 9. PMID: 39381863; PMCID: PMC11667655.
  3. Kelly AS, Bahlke M, Baker JL, de Beaufort C, Belin RM, Fonseca H, Hale PM, Holm JC, Hsia DS, Jastreboff AM, Juliusson PB, Murphy M, Pak J, Paul E, Rudolph B, Srivastava G, Tornøe CW, Weghuber D, Fox CK. Considerations for the design and conduct of pediatric obesity pharmacotherapy clinical trials: Proceedings of expert roundtable meetings. Pediatr Obes. 2024 Nov;19(11):e13161. doi: 10.1111/ijpo.13161. Epub 2024 Sep 17. PMID: 39289849.
  4. Rotevatn EØ, Engan M, Stensaker E, Hufthammer KO, Rygh LJ. Measuring pain intensity through physical interaction in an experimental model of cold-induced pain: A method comparison study. Scand J Pain. 2024 Jun 17;24(1). doi: 10.1515/sjpain-2024-0011. PMID: 38881392.
  5. Wallace EL, Goker-Alpan O, Wilcox WR, Holida M, Bernat J, Longo N, Linhart A, Hughes DA, Hopkin RJ, Tøndel C, Langeveld M, Giraldo P, Pisani A, Germain DP, Mehta A, Deegan PB, Molnar MJ, Ortiz D, Jovanovic A, Muriello M, Barshop BA, Kimonis V, Vujkovac B, Nowak A, Geberhiwot T, Kantola I, Knoll J, Waldek S, Nedd K, Karaa A, Brill-Almon E, Alon S, Chertkoff R, Rocco R, Sakov A, Warnock DG. Head-to-head trial of pegunigalsidase alfa versus agalsidase beta in patients with Fabry disease and deteriorating renal function: results from the 2-year randomised phase III BALANCE study. J Med Genet. 2024 May 21;61(6):520-530. doi: 10.1136/jmg-2023-109445. PMID: 37940383; PMCID: PMC11137442.
  6. Linhart A, Dostálová G, Nicholls K, West ML, Tøndel C, Jovanovic A, Giraldo P, Vujkovac B, Geberhiwot T, Brill-Almon E, Alon S, Chertkoff R, Rocco R, Hughes D. Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study. Orphanet J Rare Dis. 2023 Oct 21;18(1):332. doi: 10.1186/s13023-023-02937-6. PMID: 37865771.
  7. Bradley JS, Makieieva N, Tøndel C, Roilides E, Kelly MS, Patel M, Vaddady P, Maniar A, Zhang Y, Paschke A, Chen LF. Pharmacokinetics, Safety, and Tolerability of Imipenem/Cilastatin/Relebactam in Children with Confirmed or Suspected Gram-Negative Bacterial Infections: A Phase 1b, Open-Label, Single-Dose Clinical Trial. J Clin Pharmacol. 2023 Aug 10. doi: 10.1002/jcph.2334. Epub ahead of print. PMID: 37562063.
  8. Lynggaard LS, Vaitkeviciene G, Langenskiöld C, Lehmann AK, Lähteenmäki PM, Lepik K, El Hariry I, Schmiegelow K, Albertsen BK. Asparaginase encapsulated in erythrocytes as second-line treatment in hypersensitive patients with acute lymphoblastic leukaemia. Br J Haematol. 2022 Jun;197(6):745-754. doi: 10.1111/bjh.18152. Epub 2022 Mar 28. PMID: 35344210.
  9. van der Veen SJ, Körver S, Hirsch A, Hollak CEM, Wijburg FA, Brands MM, Tøndel C, van Kuilenburg ABP, Langeveld M. Early start of enzyme replacement therapy in pediatric male patients with classical Fabry disease is associated with attenuated disease progression. Mol Genet Metab. 2022 Feb;135(2):163-169. doi: 10.1016/j.ymgme.2021.12.004. Epub 2021 Dec 17. PMID: 35033446.
  10. Casabona G, Habib MA, Povey M, Riise Bergsaker MA, Flodmark CE, Espnes KA, Tøndel C, Silfverdal SA. Randomised controlled trial showed long-term efficacy, immunogenicity and safety of varicella vaccines in Norwegian and Swedish children. Acta Paediatr. 2022 Feb;111(2):391-400. doi: 10.1111/apa.16136. Epub 2021 Oct 28. PMID: 34606114; PMCID: PMC9297935.
  11. van der Zanden TM, Mooij MG, Vet NJ, Neubert A, Rascher W, Lagler FB, Male C, Grytli H, Halvorsen T, de Hoog M, de Wildt SN. Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework. Clin Pharmacol Ther. 2021 Oct;110(4):952-965. doi: 10.1002/cpt.2336. Epub 2021 Jul 29. PMID: 34145575; PMCID: PMC8518427.
  12. Baka-Ostrowska M, Bolong DT, Persu C, Tøndel C, Steup A, Lademacher C, Martin N. Efficacy and safety of mirabegron in children and adolescents with neurogenic detrusor overactivity: An open-label, phase 3, dose-titration study. Neurourol Urodyn. 2021 Aug;40(6):1490-1499. doi: 10.1002/nau.24657. Epub 2021 May 31. PMID: 34058027; PMCID: PMC8361978.
  13. Arrieta AC, Ang JY, Espinosa C, Fofanov O, Tøndel C, Chou MZ, De Anda CS, Kim JY, Li D, Sabato P, Sears PS, Bradley JS. Pharmacokinetics and Safety of Single-dose Tedizolid Phosphate in Children 2 to <12 Years of Age. Pediatr Infect Dis J. 2021 Apr 1;40(4):317-323. doi: 10.1097/INF.0000000000003030. PMID: 33710976.
  14. Moreno-Martinez D, Aguiar P, Auray-Blais C, Beck M, Bichet DG, Burlina A, Cole D, Elliott P, Feldt-Rasmussen U, Feriozzi S, Fletcher J, Giugliani R, Jovanovic A, Kampmann C, Langeveld M, Lidove O, Linhart A, Mauer M, Moon JC, Muir A, Nowak A, Oliveira JP, Ortiz A, Pintos-Morell G, Politei J, Rozenfeld P, Schiffmann R, Svarstad E, Talbot AS, Thomas M, Tøndel C, Warnock D, West ML, Hughes DA. Standardising clinical outcomes measures for adult clinical trials in Fabry disease: A global Delphi consensus. Mol Genet Metab. 2021 Apr;132(4):234-243. doi: 10.1016/j.ymgme.2021.02.001. Epub 2021 Feb 20. PMID: 33642210.
  15. Halton J, Brandão LR, Luciani M, Bomgaars L, Chalmers E, Mitchell LG, Nurmeev I, Sharathkumar A, Svirin P, Gorbatikov K, Tartakovsky I, Simetzberger M, Huang F, Sun Z, Kreuzer J, Gropper S, Reilly P, Brueckmann M, Albisetti M; DIVERSITY Trial Investigators. Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial. Lancet Haematol. 2021 Jan;8(1):e22-e33. doi: 10.1016/S2352-3026(20)30368-9. Epub 2020 Dec 5. PMID: 33290737.
  16. Santos RD, Ruzza A, Hovingh GK, Wiegman A, Mach F, Kurtz CE, Hamer A, Bridges I, Bartuli A, Bergeron J, Szamosi T, Santra S, Stefanutti C, Descamps OS, Greber-Platzer S, Luirink I, Kastelein JJP, Gaudet D; HAUSER-RCT Investigators. Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia. N Engl J Med. 2020 Oct 1;383(14):1317-1327. doi: 10.1056/NEJMoa2019910. Epub 2020 Aug 29. PMID: 32865373.
  17. Mohn KG, Brokstad KA, Islam S, Oftung F, Tøndel C, Aarstad HJ, Cox RJ. Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children. J Infect Dis. 2020 Apr 7;221(9):1528-1537. doi: 10.1093/infdis/jiz583. PMID: 32255493; PMCID: PMC7137893.
  18. Rittig S, Baka-Ostrowska M, Tøndel C, Walle JV, Kjaeer B, Passier P, Bosman B, Stroosma O, Tannenbaum S. The pharmacokinetics, safety, and tolerability of mirabegron in children and adolescents with neurogenic detrusor overactivity or idiopathic overactive bladder and development of a population pharmacokinetic model-based pediatric dose estimation. J Pediatr Urol. 2020 Feb;16(1):31.e1-31.e10. doi: 10.1016/j.jpurol.2019.10.009. Epub 2019 Oct 22. PMID: 31787582.
  19. Brandão LR, Albisetti M, Halton J, Bomgaars L, Chalmers E, Mitchell LG, Nurmeev I, Svirin P, Kuhn T, Zapletal O, Tartakovsky I, Simetzberger M, Huang F, Sun Z, Kreuzer J, Gropper S, Brueckmann M, Luciani M; DIVERSITY Study Investigators. Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children. Blood. 2020 Feb 13;135(7):491-504. doi: 10.1182/blood.2019000998. Erratum in: Blood. 2020 May 7;135(19):1720. PMID: 31805182; PMCID: PMC7019192.
  20. Naumburg E, Rane A, Halvorsen T, Glosli H, Henriksen TB, Haraldsson À, Kallio J, Lepola P. Tardy development of safe medicines for children: a Nordic network offers new platform to reduce this inequity. Acta Paediatr. 2019 Jun;108(6):992-993. doi: 10.1111/apa.14775. Epub 2019 Apr 7. PMID: 30844088.
  21. Hem IR, Gjerstad C, Berg A. Bruk av insentiver til deltagere i medisinsk og helsefaglig forskning i Norge [Use of incentives for participants in medical and health research in Norway]. Tidsskr Nor Laegeforen. 2019 Feb 11;139(3). Norwegian. doi: 10.4045/tidsskr.17.0958. PMID: 30754941.
  22. Ramaswami U, Bichet DG, Clarke LA, Dostalova G, Fainboim A, Fellgiebel A, Forcelini CM, An Haack K, Hopkin RJ, Mauer M, Najafian B, Scott CR, Shankar SP, Thurberg BL, Tøndel C, Tylki-Szymanska A, Bénichou B, Wijburg FA. Low-dose agalsidase beta treatment in male pediatric patients with Fabry disease: A 5-year randomized controlled trial. Mol Genet Metab. 2019 May;127(1):86-94. doi: 10.1016/j.ymgme.2019.03.010. Epub 2019 Apr 3. PMID: 30987917.
  23. Mikalsen IB, Karlstad Ø, Furu K, Øymar K. Prescribing of asthma drugs for children 2004-2015. Tidsskr Nor Laegeforen. 2018 Feb 19;138(4). English, Norwegian. doi: 10.4045/tidsskr.17.0227. PMID: 29460600.
  24. Berg A, Arntzen E. Ny og bedre spesialistutdanning for legene [New and better specialist training for the physicians]. Tidsskr Nor Laegeforen. 2017 Sep 5;137(17). Norwegian. doi: 10.4045/tidsskr.17.0603. PMID: 28925194.
  25. Mohn KG, Brokstad KA, Pathirana RD, Bredholt G, Jul-Larsen Å, Trieu MC, Lartey SL, Montomoli E, Tøndel C, Aarstad HJ, Cox RJ. Live Attenuated Influenza Vaccine in Children Induces B-Cell Responses in Tonsils. J Infect Dis. 2016 Sep 1;214(5):722-31. doi: 10.1093/infdis/jiw230. Epub 2016 May 30. Erratum in: J Infect Dis. 2016 Oct 3;: PMID: 27247344; PMCID: PMC4978372.
  26. Berg A, Gjerstad C, Ruyter KW. Å skille diagnostikk og forskning [Distinguishing diagnostics from research]. Tidsskr Nor Laegeforen. 2016 Feb 23;136(4):302. Norwegian. doi: 10.4045/tidsskr.15.1352. PMID: 26905843.
  27. Wijburg FA, Bénichou B, Bichet DG, Clarke LA, Dostalova G, Fainboim A, Fellgiebel A, Forcelini C, An Haack K, Hopkin RJ, Mauer M, Najafian B, Scott CR, Shankar SP, Thurberg BL, Tøndel C, Tylki-Szymańska A, Ramaswami U. Characterization of early disease status in treatment-naive male paediatric patients with Fabry disease enrolled in a randomized clinical trial. PLoS One. 2015 May 8;10(5):e0124987. doi: 10.1371/journal.pone.0124987. PMID: 25955246; PMCID: PMC4425695.
  28. Mohn KG, Bredholt G, Brokstad KA, Pathirana RD, Aarstad HJ, Tøndel C, Cox RJ. Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children. J Infect Dis. 2015 May 15;211(10):1541-9. doi: 10.1093/infdis/jiu654. Epub 2014 Nov 25. PMID: 25425696; PMCID: PMC4407761.

 

 

 

 

Growth and Puberty

pdated knowledge of growth and weight development is important for all health-related work with children and adolescents, due to follow up of the child, but also to monitor trends in the child population. Children’s growth and development depends on heredity and environment. Norwegian children have gradually grown taller over the last hundred years, which reflects among other things, better well-being, improved nutrition and fewer infections. In the last 20-30 years weight in older children and adults has also increased.

Vekststudien i Bergen 1 og 2 | The Bergen Growth Study 1 and 2

PhD dissertations:

 

Peer review publications:

  1. Forthun IH, Roelants M, Knutsen HK, Haug LS, Iszatt N, Schell LM, Jugessur A, Bjerknes R, Oehme NB, Madsen A, Bruserud IS, Juliusson PB. Exposure to Per- and Polyfluoroalkyl Substances and Timing of Puberty in Norwegian Boys: Data from the Bergen Growth Study 2. Environ Sci Technol. 2024 Sep 17;58(37):16336-16346. doi: 10.1021/acs.est.4c06062. Epub 2024 Sep 3. PMID: 39226441; PMCID: PMC11411722.
  2. Talmo MSA, Fløysand IS, Nilsen GØ, Løvvik TS, Ødegård R, Juliusson PB, Vanky E, Simpson MR. Growth Restriction in the Offspring of Mothers With Polycystic Ovary Syndrome. JAMA Netw Open. 2024 Aug 1;7(8):e2430543. doi: 10.1001/jamanetworkopen.2024.30543. PMID: 39190302; PMCID: PMC11350484.
  3. Moen OK, Júlíusson PB, Roelants M, Spielau U. Seasonal variability in body mass index, waist circumference, and skinfolds in Norwegian children. Am J Hum Biol. 2024 Apr 12:e24084. doi: 10.1002/ajhb.24084. Epub ahead of print. PMID: 38613139.
  4. Helgeland Ø, Vaudel M, Sole-Navais P, Flatley C, Juodakis J, Bacelis J, Koløen IL, Knudsen GP, Johansson BB, Magnus P, Kjennerud TR, Juliusson PB, Stoltenberg C, Holmen OL, Andreassen OA, Jacobsson B, Njølstad PR, Johansson S. Author Correction: Characterization of the genetic architecture of infant and early childhood body mass index. Nat Metab. 2024 Feb;6(2):378. doi: 10.1038/s42255-024-01004-z. Erratum for: Nat Metab. 2022 Mar;4(3):344-358. doi: 10.1038/s42255-022-00549-1. PMID: 38337098.
  5. Juliusson PB, Roelants M. Should the Prader 3-mL orchidometer bead change colour? Acta Paediatr. 2023 Nov;112(11):2269-2270. doi: 10.1111/apa.16963. Epub 2023 Sep 4. PMID: 37667474.
  6. Juliusson PB, Roelants M. Should the Prader 3-mL orchidometer bead change colour? Acta Paediatr. 2023 Nov;112(11):2269-2270. doi: 10.1111/apa.16963. Epub 2023 Sep 4. PMID: 37667474.
  7. Balthasar MR, Roelants M, Brannsether-Ellingsen B, Stangenes KM, Magnus MC, Håberg SE, Øverland SN, JulÍusson PB. Evaluating national guidelines for monitoring early growth using routinely collected data in Bergen, Norway. Scand J Public Health. 2023 Jul 27:14034948231187513. doi: 10.1177/14034948231187513. Epub ahead of print. PMID: 37496420.
  8. Nilsen GØ, Simpson MR, Hanem LGE, Løvvik TS, Ødegård R, Stokkeland LMT, Andersen MS, Juliusson PB, Vanky E. Anthropometrics of neonates born to mothers with PCOS with metformin or placebo exposure in utero. Acta Obstet Gynecol Scand. 2023 Jul 24. doi: 10.1111/aogs.14637. Epub ahead of print. PMID: 37488743.
  9. Juliusson PB, Bruserud IS, Oehme NHB, Madsen A, Forthun IH, Balthasar M, Rosendahl K, Viste K, Jugessur A, Schell LM, Bjerknes R, Roelants M. Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2. Ann Hum Biol. 2023 Feb;50(1):226-235. doi: 10.1080/03014460.2023.2174272. PMID: 37358552.
  10. Forthun IH, Roelants M, Haug LS, Knutsen HK, Schell LM, Jugessur A, Bjerknes R, Sabaredzovic A, Bruserud IS, Juliusson PB. Levels of per- and polyfluoroalkyl substances (PFAS) in Norwegian children stratified by age and sex - Data from the Bergen Growth Study 2. Int J Hyg Environ Health. 2023 Jul;252:114199. doi: 10.1016/j.ijheh.2023.114199. Epub 2023 Jun 7. PMID: 37295275.
  11. Madsen A, Almås B, Bruserud IS, Oehme NHB, Nielsen CS, Roelants M, Hundhausen T, Ljubicic ML, Bjerknes R, Mellgren G, Sagen JV, Juliusson PB, Viste K. Reference Curves for Pediatric Endocrinology: Leveraging Biomarker Z-Scores for Clinical Classifications. J Clin Endocrinol Metab. 2022 Jun 16;107(7):2004-2015. doi: 10.1210/clinem/dgac155. PMID: 35299255; PMCID: PMC9202734.
  12. Linde LE, Ebbing C, Moster D, Kessler J, Baghestan E, Gissler M, Rasmussen S. Recurrence of postpartum hemorrhage, maternal and paternal contribution, and the effect of offspring birthweight and sex: a population-based cohort study. Arch Gynecol Obstet. 2022 Nov;306(5):1807-1814. doi: 10.1007/s00404-021-06374-3. Epub 2022 Jan 9. PMID: 34999924; PMCID: PMC9519656.
  13. Svanes C, Bertelsen RJ, Accordini S, Holloway JW, Júlíusson P, Boateng E, Krauss-Etchmann S, Schlünssen V, Gómez-Real F, Skulstad SM. Exposures during the prepuberty period and future offspring's health: evidence from human cohort studies†. Biol Reprod. 2021 Sep 14;105(3):667-680. doi: 10.1093/biolre/ioab158. PMID: 34416759; PMCID: PMC8444705
  14. Bruserud IS, Oehme NHB, Madsen A, Rosendahl K, Bjerknes R, Roelants M, Júlíusson PB. Puberty starts earlier. Tidsskr Nor Laegeforen. 2021 Apr 21;141(7). English, Norwegian. doi: 10.4045/tidsskr.21.0210. PMID: 33950643.
  15. Wilcox AJ, Cortese M, McConnaughey DR, Moster D, Basso O. The limits of small-for-gestational-age as a high-risk category. Eur J Epidemiol. 2021 Oct;36(10):985-991. doi: 10.1007/s10654-021-00810-z. Epub 2021 Oct 18. PMID: 34661814.
  16. Ueland GÅ, Kellmann R, Jørstad Davidsen M, Viste K, Husebye ES, Almås B, Storr HL, Sagen JV, Mellgren G, Júlíusson PB, Methlie P. Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children. J Endocr Soc. 2021 Mar 4;5(5):bvab033. doi: 10.1210/jendso/bvab033. PMID: 33928203; PMCID: PMC8064046.
  17. Magnus MC, Wilcox AJ, Fadum EA, Gjessing HK, Opdahl S, Juliusson PB, Romundstad LB, Håberg SE. Growth in children conceived by ART. Hum Reprod. 2021 Mar 18;36(4):1074-1082. doi: 10.1093/humrep/deab007. PMID: 33592626; PMCID: PMC7970724.
  18. Oehme NHB, Roelants M, Bruserud IS, Madsen A, Bjerknes R, Rosendahl K, Juliusson PB. Low BMI, but not high BMI, influences the timing of puberty in boys. Andrology. 2021 May;9(3):837-845. doi: 10.1111/andr.12985. Epub 2021 Feb 17. PMID: 33544961.
  19. Rohrer TR, Abuzzahab J, Backeljauw P, Birkegård AC, Blair J, Dahlgren J, Júlíusson PB, Ostrow V, Pietropoli A, Polak M, Romano A, Ross J, Sävendahl L, Miller BS. Long-Term Effectiveness and Safety of Childhood Growth Hormone Treatment in Noonan Syndrome. Horm Res Paediatr. 2020;93(6):380-395. doi: 10.1159/000512429. Epub 2021 Jan 13. PMID: 33440388.
  20. Madsen A, Bruserud IS, Bertelsen BE, Roelants M, Oehme NHB, Viste K, Bjerknes R, Almås B, Rosendahl K, Mellgren G, Sagen JV, Juliusson PB. Hormone References for Ultrasound Breast Staging and Endocrine Profiling to Detect Female Onset of Puberty. J Clin Endocrinol Metab. 2020 Dec 1;105(12):e4886–95. doi: 10.1210/clinem/dgaa679. PMID: 32961560; PMCID: PMC7571452.
  21. Schei K, Simpson MR, Avershina E, Rudi K, Øien T, Júlíusson PB, Underhill D, Salamati S, Ødegård RA. Early Gut Fungal and Bacterial Microbiota and Childhood Growth. Front Pediatr. 2020 Nov 9;8:572538. doi: 10.3389/fped.2020.572538. PMID: 33240830; PMCID: PMC7680752.
  22. Oehme N, Bruserud IS, Madsen A, Júlíusson PB. Is puberty starting earlier than before? Tidsskr Nor Laegeforen. 2020 Aug 31;140(12). English, Norwegian. doi: 10.4045/tidsskr.20.0043. PMID: 32900174.
  23. Bruserud IS, Roelants M, Oehme NHB, Madsen A, Eide GE, Bjerknes R, Rosendahl K, Juliusson PB. References for Ultrasound Staging of Breast Maturation, Tanner Breast Staging, Pubic Hair, and Menarche in Norwegian Girls. J Clin Endocrinol Metab. 2020 May 1;105(5):1599–607. doi: 10.1210/clinem/dgaa107. PMID: 32140730; PMCID: PMC7275631.
  24. Oehme NHB, Roelants M, Saervold Bruserud I, Madsen A, Eide GE, Bjerknes R, Rosendahl K, Juliusson PB. Reference data for testicular volume measured with ultrasound and pubic hair in Norwegian boys are comparable with Northern European populations. Acta Paediatr. 2020 Aug;109(8):1612-1619. doi: 10.1111/apa.15159. Epub 2020 Jan 22. PMID: 31899821.
  25. Juliusson PB, Dagbjartsson A, Roelants M, Palsson G, Fridjonsdottir H, Einarsdottir R, Thorsson AV. Larger head circumference in Icelandic children 0-4 years of age compared to the World Health Organization and Swedish growth charts. Acta Paediatr. 2020 Jun;109(6):1184-1189. doi: 10.1111/apa.15103. Epub 2019 Dec 5. PMID: 31755566.
  26. Bjertnaes AA, Grundt JH, Juliusson PB, Markestad TJ, Strand TA, Holten-Andersen MN. Sex-related change in BMI of 15- to 16-year-old Norwegian girls in cross-sectional studies in 2002 and 2017. BMC Pediatr. 2019 Nov 12;19(1):431. doi: 10.1186/s12887-019-1790-2. PMID: 31718598; PMCID: PMC6849237.
  27. Madsen A, Oehme NB, Roelants M, Bruserud IS, Eide GE, Viste K, Bjerknes R, Almås B, Rosendahl K, Sagen JV, Mellgren G, Juliusson PB. Testicular Ultrasound to Stratify Hormone References in a Cross-Sectional Norwegian Study of Male Puberty. J Clin Endocrinol Metab. 2020 Jun 1;105(6):dgz094. doi: 10.1210/clinem/dgz094. PMID: 31697832.
  28. Helgeland Ø, Vaudel M, Juliusson PB, Lingaas Holmen O, Juodakis J, Bacelis J, Jacobsson B, Lindekleiv H, Hveem K, Lie RT, Knudsen GP, Stoltenberg C, Magnus P, Sagen JV, Molven A, Johansson S, Njølstad PR. Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth. Nat Commun. 2019 Oct 1;10(1):4448. doi: 10.1038/s41467-019-12308-0. PMID: 31575865; PMCID: PMC6773698.
  29. Bruserud IS, Roelants M, Oehme NHB, Eide GE, Bjerknes R, Rosendahl K, Júlíusson PB. Ultrasound assessment of pubertal breast development in girls: intra- and interobserver agreement. Pediatr Radiol. 2018 Oct;48(11):1576-1583. doi: 10.1007/s00247-018-4188-7. Epub 2018 Jul 7. PMID: 29982956.
  30. Oehme NHB, Roelants M, Bruserud IS, Eide GE, Bjerknes R, Rosendahl K, Júlíusson PB. Ultrasound-based measurements of testicular volume in 6- to 16-year-old boys - intra- and interobserver agreement and comparison with Prader orchidometry. Pediatr Radiol. 2018 Nov;48(12):1771-1778. doi: 10.1007/s00247-018-4195-8. Epub 2018 Jul 6. PMID: 29980860.
  31. Kløvgaard M, Nielsen NO, Sørensen TL, Bjerregaard P, Olsen B, Júlíusson PB, Roelants M, Christesen HT. Growth of children in Greenland exceeds the World Health Organization growth charts. Acta Paediatr. 2018 Nov;107(11):1953-1965. doi: 10.1111/apa.14369. Epub 2018 May 21. PMID: 29693738; PMCID: PMC6221127.
  32. Rosendahl K, Bruserud IS, Oehme N, Júlíusson PB, de Horatio LT, Müller LO, Magni-Manzoni S. Normative ultrasound references for the paediatric wrist; dorsal soft tissues. RMD Open. 2018 Mar 10;4(1):e000642. doi: 10.1136/rmdopen-2017-000642. PMID: 29556421; PMCID: PMC5856916.
  33. Júlíusson PB, Hjelmesæth J, Bjerknes R, Roelants M. New curves for body mass index among children and adolescents. Tidsskr Nor Laegeforen. 2017 Oct 2;137(18). Norwegian, English. doi: 10.4045/tidsskr.17.0570. PMID: 28972329.
  34. Bratke H, Bruserud IS, Brannsether B, Aßmus J, Bjerknes R, Roelants M, Júlíusson PB. Timing of menarche in Norwegian girls: associations with body mass index, waist circumference and skinfold thickness. BMC Pediatr. 2017 Jun 6;17(1):138. doi: 10.1186/s12887-017-0893-x. PMID: 28587648; PMCID: PMC5461627.
  35. Byberg KK, Øymar K, Eide GE, Forman MR, Júlíusson PB. Exposure to preeclampsia in utero affects growth from birth to late childhood dependent on child's sex and severity of exposure: Follow-up of a nested case-control study. PLoS One. 2017 May 9;12(5):e0176627. doi: 10.1371/journal.pone.0176627. PMID: 28486480; PMCID: PMC5423584.
  36. Brannsether B, Roelants M, Bjerknes R, Júlíusson PB. New reference charts for weight-related body measurements in children. Tidsskr Nor Laegeforen. 2016 Nov 22;136(21):1828-1830. English, Norwegian. doi: 10.4045/tidsskr.16.0574. PMID: 27883109.
  37. Christesen HT, Pedersen BT, Pournara E, Petit IO, Júlíusson PB. Short Stature: Comparison of WHO and National Growth Standards/References for Height. PLoS One. 2016 Jun 9;11(6):e0157277. doi: 10.1371/journal.pone.0157277. PMID: 27280591; PMCID: PMC4900602.
  38. Brannsether B, Eide GE, Roelants M, Bjerknes R, Júlíusson PB. BMI and BMI SDS in childhood: annual increments and conditional change. Ann Hum Biol. 2017 Feb;44(1):28-33. doi: 10.3109/03014460.2016.1151933. Epub 2016 Mar 10. PMID: 26862707.
  39. Amare EB, Idsøe M, Wiksnes M, Moss T, Roelants M, Shimelis D, Júlíusson PB, Kiserud T, Wester K. Reference Ranges for Head Circumference in Ethiopian Children 0-2 Years of Age. World Neurosurg. 2015 Dec;84(6):1566-71.e1-2. doi: 10.1016/j.wneu.2015.08.045. Epub 2015 Sep 3. PMID: 26342781.
  40. Júlíusson PB, Brannsether B, Kristiansen H, Hoppenbrouwers K, Bjerknes R, Roelants M. Should children with overweight or obesity be excluded from height references? Arch Dis Child. 2015 Nov;100(11):1044-8. doi: 10.1136/archdischild-2015-308537. Epub 2015 Aug 21. PMID: 26297699.
  41. Finbråten AK, Martins C, Andersen GL, Skranes J, Brannsether B, Júlíusson PB, Syversen U, Stevenson RD, Vik T. Assessment of body composition in children with cerebral palsy: a cross-sectional study in Norway. Dev Med Child Neurol. 2015 Sep;57(9):858-64. doi: 10.1111/dmcn.12752. Epub 2015 Apr 1. PMID: 25827868.
  42. Blankenstein O, Pedersen BT, Schlumpf M, Andreasen AH, Júlíusson PB. Management and interpretation of heterogeneous observational data: using insulin-like growth factor-I data from the NordiNet® International Outcome Study. Growth Horm IGF Res. 2015 Feb;25(1):41-6. doi: 10.1016/j.ghir.2014.12.001. Epub 2014 Dec 9. PMID: 25542446.
  43. Jensen ET, Daniels JL, Stürmer T, Robinson WR, Williams CJ, Moster D, Juliusson PB, Vejrup K, Magnus P, Longnecker MP. Maternal hormonal contraceptive use and offspring overweight or obesity. Int J Obes (Lond). 2014 Oct;38(10):1275-81. doi: 10.1038/ijo.2014.114. Epub 2014 Jul 2. PMID: 24984751; PMCID: PMC4365991.
  44. Glavin K, Roelants M, Strand BH, Júlíusson PB, Lie KK, Helseth S, Hovengen R. Important periods of weight development in childhood: a population-based longitudinal study. BMC Public Health. 2014 Feb 13;14:160. doi: 10.1186/1471-2458-14-160. PMID: 24524269; PMCID: PMC3925776.
  45. Brannsether B, Roelants M, Bjerknes R, Júlíusson PB. References and cutoffs for triceps and subscapular skinfolds in Norwegian children 4-16 years of age. Eur J Clin Nutr. 2013 Sep;67(9):928-33. doi: 10.1038/ejcn.2013.91. Epub 2013 May 1. PMID: 23632751.
  46. Júlíusson PB, Roelants M, Nordal E, Furevik L, Eide GE, Moster D, Hauspie R, Bjerknes R. Growth references for 0-19 year-old Norwegian children for length/height, weight, body mass index and head circumference. Ann Hum Biol. 2013 May;40(3):220-7. doi: 10.3109/03014460.2012.759276. Epub 2013 Feb 18. PMID: 23414181.
  47. Milani S, Buckler JM, Kelnar CJ, Benso L, Gilli G, Nicoletti I, Faglia G, Radetti G, Bona G, Schonbeck Y, Van Buuren S, Hermanussen M, Grugni G, Marazzi N, Júlíusson PB, Roelants M, Hoppenbrouwers K, Hauspie R, Bjerknes R, Lejarraga H, Sartorio A. The use of local reference growth charts for clinical use or a universal standard: a balanced appraisal. J Endocrinol Invest. 2012 Feb;35(2):224-6. doi: 10.1007/BF03345422. PMID: 22490992.
  48. Brannsether B, Roelants M, Bjerknes R, Júlíusson PB. Waist circumference and waist-to-height ratio in Norwegian children 4-18 years of age: reference values and cut-off levels. Acta Paediatr. 2011 Dec;100(12):1576-82. doi: 10.1111/j.1651-2227.2011.02370.x. Epub 2011 Jun 16. PMID: 21627692.
  49. Bang P, Bjerknes R, Dahlgren J, Dunkel L, Gustafsson J, Juul A, Kriström B, Tapanainen P, Aberg V. A comparison of different definitions of growth response in short prepubertal children treated with growth hormone. Horm Res Paediatr. 2011;75(5):335-45. doi: 10.1159/000322878. Epub 2011 Jan 12. PMID: 21228552.
  50. Westerberg AC, Henriksen C, Ellingvåg A, Veierød MB, Júlíusson PB, Nakstad B, Aurvåg AK, Rønnestad A, Grønn M, Iversen PO, Drevon CA. First year growth among very low birth weight infants. Acta Paediatr. 2010 Apr;99(4):556-62. doi: 10.1111/j.1651-2227.2009.01667.x. Epub 2010 Jan 20. PMID: 20096031.
  51. Júlíusson PB, Roelants M, Hoppenbrouwers K, Hauspie R, Bjerknes R. Growth of Belgian and Norwegian children compared to the WHO growth standards: prevalence below -2 and above +2 SD and the effect of breastfeeding. Arch Dis Child. 2011 Oct;96(10):916-21. doi: 10.1136/adc.2009.166157. Epub 2009 Nov 30. PMID: 19948662.
  52. Júlíusson PB, Roelants M, Eide GE, Moster D, Juul A, Hauspie R, Waaler PE, Bjerknes R. Vekstkurver for norske barn [Growth references for Norwegian children]. Tidsskr Nor Laegeforen. 2009 Feb 12;129(4):281-6. Norwegian. doi: 10.4045/tidsskr.09.32473. PMID: 19219092.
  53. Virtanen HE, Bjerknes R, Cortes D, Jørgensen N, Rajpert-De Meyts E, Thorsson AV, Thorup J, Main KM. Cryptorchidism: classification, prevalence and long-term consequences. Acta Paediatr. 2007 May;96(5):611-6. doi: 10.1111/j.1651-2227.2007.00241.x. PMID: 17462053.
  54. Berg JP, Bjerknes R. Molekylaerdiagnostikk av endokrine sykdommer [Molecular diagnostics in endocrine diseases]. Tidsskr Nor Laegeforen. 2005 Nov 3;125(21):2959-63. Norwegian. PMID: 16276381.
  55. Ritzén EM, Bergh A, Bjerknes R, Christiansen P, Cortes D, Haugen SE, Jörgensen N, Kollin C, Lindahl S, Läckgren G, Main KM, Nordenskjöld A, Rajpert-De Meyts E, Söder O, Taskinen S, Thorsson A, Thorup J, Toppari J, Virtanen H. Nordic consensus on treatment of undescended testes. Acta Paediatr. 2007 May;96(5):638-43. doi: 10.1111/j.1651-2227.2006.00159.x. Epub 2007 Feb 26. PMID: 17326760.
  56. Bjerknes R. Hvordan identifisere binyrebarksuppresjon hos barn som behandles med inhalasjonssteroider? [How to identify adrenal cortex suppression in children treated with inhalation steroids?]. Tidsskr Nor Laegeforen. 2005 Aug 11;125(15):2033. Norwegian. PMID: 16114125.
  57. Angell-Andersen E, Tretli S, Bjerknes R, Forsén T, Sørensen TI, Eriksson JG, Räsänen L, Grotmol T. The association between nutritional conditions during World War II and childhood anthropometric variables in the Nordic countries. Ann Hum Biol. 2004 May-Jun;31(3):342-55. doi: 10.1080/03014460410001685304. PMID: 15204349.
  58. Bjerknes R. Barn er ikke små voksne [Children are not small adults]. Tidsskr Nor Laegeforen. 2001 Feb 20;121(5):549. Norwegian. PMID: 11301604.
  59. Bjerknes R, Skadberg B, Njølstad PR. Astma, inhalasjonssteroider og vekst [Asthma, steroid inhalation and growth]. Tidsskr Nor Laegeforen. 2001 Jan 30;121(3):281. Norwegian. PMID: 11242865.
  60. Haug K, Irgens LM, Skjaerven R, Markestad T, Baste V, Schreuder P. Maternal smoking and birthweight: effect modification of period, maternal age and paternal smoking. Acta Obstet Gynecol Scand. 2000 Jun;79(6):485-9. PMID: 10857873.
  61. Markestad T, Vik T, Ahlsten G, Gebre-Medhin M, Skjaerven R, Jacobsen G, Hoffman HJ, Bakketeig LS. Small-for-gestational-age (SGA) infants born at term: growth and development during the first year of life. Acta Obstet Gynecol Scand Suppl. 1997;165:93-101. PMID: 9219465.
  62. Vik T, Markestad T, Ahlsten G, Gebre-Medhin M, Jacobsen G, Hoffman HJ, Bakketeig LS. Body proportions and early neonatal morbidity in small-for-gestational-age infants of successive births. Acta Obstet Gynecol Scand Suppl. 1997;165:76-81. PMID: 9219462.
  63. Markestad T, Lossius P, Maartmann-Moe H, Iversen OE, Lie RT, Bergsjø P, Jacobsen G, Hoffman HJ, Bakketeig LS. Cell division in placentas of appropriate and small-for-gestational-age infants. A flow cytometry study. Acta Obstet Gynecol Scand Suppl. 1997;165:59-62. PMID: 9219459.
  64. Markestad T, Lossius P, Maartmann-Moe H, Iversen OE, Lie RT, Bergsjø P, Jacobsen G, Hoffman HJ, Bakketeig LS. Cell division in placentas of appropriate and small-for-gestational-age infants. A flow cytometry study. Acta Obstet Gynecol Scand Suppl. 1997;165:59-62. PMID: 9219459.
  65. Markestad T, Bergsjø P, Aakvaag A, Lie RT, Jacobsen G, Hoffman HJ, Bakketeig LS. Prediction of fetal growth based on maternal serum concentrations of human chorionic gonadotropin, human placental lactogen and estriol. Acta Obstet Gynecol Scand Suppl. 1997;165:50-5. PMID: 9219457.
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  67. Bergsjø P, Hoffman HJ, Davis RO, Goldenberg RL, Lindmark G, Jacobsen G, Cutter G, Markestad T, Nelson KG, Bakketeig LS. Preliminary results from the Collaborative Alabama and Scandinavian Study of Successive Small-for-Gestational Age Births. Acta Obstet Gynecol Scand. 1989;68(1):19-25. doi: 10.3109/00016348909087683. PMID: 2801026.
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Media:

9. mars 2020: https://www.bt.no/nyheter/lokalt/i/EWnBnj/norske-jenter-faar-mensen-tidligere

1. oktober 2019: https://www.nrk.no/livsstil/barn-kommer-stadig-tidligere-i-puberteten-1.14705163

5. oktober 2019: https://www.aftenposten.no/norge/i/b5dO5k/barn-som-lever-med-steforeldre-eller-halvsoesken-legger-ekstra-paa-seg

20. mars 2015: http://www.nrk.no/viten/unik-pubertetsstudie-i-norge-1.122689072013/oktober/368735

17. oktober 2013: http://www.forskning.no/artikler/2013/oktober/368735

13. september 2013: http://www.forskning.no/artikler/2013/september/366871

4. april 2010: http://nyheter.uib.no/?modus=vis_nyhet&id=45817

12. februar 2009: http://www.bt.no/forbruker/helse/article791291.ece

29. september 2008: http://www.vg.no/helse/artikkel.php?artid=517228

19. april 2005: http://www.aftenposten.no/helse/article1020809.ece

Nutrition and Overweight

Adequate nutrition is vital to secure good health from conception and throughout life.

PhD dissertations:

 

Peer review publications:

  1. Balthasar MR, Roelants M, Brannsether-Ellingsen B, Bjarnason R, Bergh IH, Kvalvik LG, Stangenes KM, Jugessur A, Tollånes MC, Markussen F, Juliusson PB. Trends in overweight and obesity in Bergen, Norway, using data from routine child healthcare 2010-2022. Acta Paediatr. 2024 Sep;113(9):2098-2106. doi: 10.1111/apa.17323. Epub 2024 Jun 19. PMID: 38895765.
  2. Hapnes NC, Stensvold HJ, Bjørnland K, Sæter T, Guthe HJT, Støen R, Moltu SJ, Rønnestad A, Klingenberg C; Norwegian Neonatal Network. Surgery for intestinal injuries in very preterm infants: a Norwegian population-based study with a new approach to disease classification. BMJ Paediatr Open. 2024 Sep 18;8(1):e002722. doi: 10.1136/bmjpo-2024-002722. PMID: 39299770; PMCID: PMC11418550.
  3. Moen OK, Júlíusson PB, Roelants M, Spielau U. Seasonal variability in body mass index, waist circumference, and skinfolds in Norwegian children. Am J Hum Biol. 2024 Sep;36(9):e24084. doi: 10.1002/ajhb.24084. Epub 2024 Apr 12. PMID: 38613139.
  4. Helgeland Ø, Vaudel M, Sole-Navais P, Flatley C, Juodakis J, Bacelis J, Koløen IL, Knudsen GP, Johansson BB, Magnus P, Kjennerud TR, Juliusson PB, Stoltenberg C, Holmen OL, Andreassen OA, Jacobsson B, Njølstad PR, Johansson S. Author Correction: Characterization of the genetic architecture of infant and early childhood body mass index. Nat Metab. 2024 Feb;6(2):378. doi: 10.1038/s42255-024-01004-z. Erratum for: Nat Metab. 2022 Mar;4(3):344-358. doi: 10.1038/s42255-022-00549-1. PMID: 38337098.
  5. Øvrebø B, Kjøllesdal M, Stea TH, Wills AK, Bere E, Magnus P, Juliusson PB, Bergh IH. The influence of immigrant background and parental education on overweight and obesity in 8-year-old children in Norway. BMC Public Health. 2023 Aug 29;23(1):1660. doi: 10.1186/s12889-023-16571-1. PMID: 37644416; PMCID: PMC10466865.
  6. Closs ER, Lyamouri M, Øymar K, Størdal K. Regionale forskjeller i bruk av protonpumpehemmere hos barn [Regional differences in the use of proton pump inhibitors in children]. Tidsskr Nor Laegeforen. 2023 Jun 12;143(9). Norwegian. doi: 10.4045/tidsskr.22.0771. PMID: 37341401.
  7. Ødegård RA, Júlíusson PB, Kokkvoll AS, Kristiansen H, Köpp UMS, Rolin J, Shah S, Svendsen M, Hjelmesæth J. Ungdom med alvorlig fedme bør få legemiddel på blå resept [Adolescents with severe obesity should receive medication under the National Insurance scheme]. Tidsskr Nor Laegeforen. 2023 Feb 3;143(3). Norwegian. doi: 10.4045/tidsskr.23.0069. PMID: 36811423.
  8. Evensen M, Klitkou ST, Tollånes MC, Júlíusson PB, Kravdal Ø. Parental income gradients in child and adolescent mortality: Norwegian trends over half a century. Scand J Public Health. 2023 Feb 13:14034948231151990. doi: 10.1177/14034948231151990. Epub ahead of print. PMID: 36785495.
  9. Revheim I, Balthasar MR, Akerkar RR, Stangenes KM, Almenning G, Nygaard E, Markestad T, Øverland S, Roelants M, Juliusson PB. Trends in the prevalence of breastfeeding up to 6 months of age using structured data from routine child healthcare visits. Acta Paediatr. 2023 Jan;112(1):100-105. doi: 10.1111/apa.16367. Epub 2022 Apr 28. PMID: 35442538; PMCID: PMC10084077.
  10. Rolin J, Ødegård RA, Amundsen VV, Köpp UMS, Kokkvoll A, Júlíusson PB, Hjelmesæth J. Correction: Supplementary drug treatment to reduce weight in adolescents with severe obesity. Tidsskr Nor Laegeforen. 2023 Jan 12;143(2). English, Norwegian. doi: 10.4045/tidsskr.23.0028. PMID: 36718893.
  11. Danielsen YS, Skjåkødegård HF, Mongstad M, Hystad SW, Olsson SJG, Kleppe M, Juliusson PB, Frisk B. Objectively measured physical activity among treatment seeking children and adolescents with severe obesity and normal weight peers. Obes Sci Pract. 2022 Jun 13;8(6):801-810. doi: 10.1002/osp4.624. PMID: 36483122; PMCID: PMC9722458.
  12. Skjåkødegård HF, Hystad S, Bruserud I, Conlon RPK, Wilfley D, Frisk B, Roelants M, Juliusson PB, Danielsen YS. Perceived barriers in family-based behavioural treatment of paediatric obesity - Results from the FABO study. Pediatr Obes. 2023 Mar;18(3):e12992. doi: 10.1111/ijpo.12992. Epub 2022 Dec 5. PMID: 36468217; PMCID: PMC10078207.
  13. Rolin J, Ødegård RA, Amundsen VV, Köpp UMS, Kokkvoll A, Júlíusson PB, Hjelmesæth J. Supplementary drug treatment to reduce weight in adolescents with severe obesity. Tidsskr Nor Laegeforen. 2022 Oct 4;142(14). English, Norwegian. doi: 10.4045/tidsskr.22.0540. PMID: 36226431.
  14. Skjåkødegård HF, Conlon RPK, Hystad SW, Roelants M, Olsson SJG, Frisk B, Wilfley DE, Danielsen YS, Juliusson PB. Family-based treatment of children with severe obesity in a public healthcare setting: Results from a randomized controlled trial. Clin Obes. 2022 Jun;12(3):e12513. doi: 10.1111/cob.12513. Epub 2022 Feb 25. PMID: 35218145; PMCID: PMC9286578.
  15. Helgeland Ø, Vaudel M, Sole-Navais P, Flatley C, Juodakis J, Bacelis J, Koløen IL, Knudsen GP, Johansson BB, Magnus P, Kjennerud TR, Juliusson PB, Stoltenberg C, Holmen OL, Andreassen OA, Jacobsson B, Njølstad PR, Johansson S. Characterization of the genetic architecture of infant and early childhood body mass index. Nat Metab. 2022 Mar;4(3):344-358. doi: 10.1038/s42255-022-00549-1. Epub 2022 Mar 21. PMID: 35315439.
  16. Øvrebø B, Stea TH, Bergh IH, Bere E, Surén P, Magnus P, Juliusson PB, Wills AK. A nationwide school fruit and vegetable policy and childhood and adolescent overweight: A quasi-natural experimental study. PLoS Med. 2022 Jan 18;19(1):e1003881. doi: 10.1371/journal.pmed.1003881. PMID: 35041660; PMCID: PMC8765663.
  17. Clarsen B, Nylenna M, Klitkou ST, Vollset SE, Baravelli CM, Bølling AK, Aasvang GM, Sulo G, Naghavi M, Pasovic M, Asaduzzaman M, Bjørge T, Eggen AE, Eikemo TA, Ellingsen CL, Haaland ØA, Hailu A, Hassan S, Hay SI, Juliusson PB, Kisa A, Kisa S, Månsson J, Mekonnen T, Murray CJL, Norheim OF, Ottersen T, Sagoe D, Sripada K, Winkler AS, Knudsen AKS. Changes in life expectancy and disease burden in Norway, 1990-2019: an analysis of the Global Burden of Disease Study 2019. Lancet Public Health. 2022 Jul;7(7):e593-e605. doi: 10.1016/S2468-2667(22)00092-5. PMID: 35779543; PMCID: PMC9253891.
  18. Varsi K, Torsvik IK, Huber S, Averina M, Brox J, Bjørke-Monsen AL. Impaired gross motor development in infants with higher PFAS concentrations. Environ Res. 2022 Mar;204(Pt D):112392. doi: 10.1016/j.envres.2021.112392. Epub 2021 Nov 17. PMID: 34800539.
  19. Danielsen YS, Skjåkødegård HF, Bjorvatn B, Juliusson PB, Pallesen S. Polysomnographic comparison of sleep in children with obesity and normal weight without suspected sleep-related breathing disorder. Clin Obes. 2022 Feb;12(1):e12493. doi: 10.1111/cob.12493. Epub 2021 Nov 15. PMID: 34781415.
  20. GBD 2019 Adolescent Mortality Collaborators. Global, regional, and national mortality among young people aged 10-24 years, 1950-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2021 Oct 30;398(10311):1593-1618. doi: 10.1016/S0140-6736(21)01546-4. Epub 2021 Oct 28. Erratum in: Lancet. 2022 Feb 26;399(10327):802. PMID: 34755628; PMCID: PMC8576274.
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  90. Hellebostad M, Markestad T, Seeger Halvorsen K. Vitamin D deficiency rickets and vitamin B12 deficiency in vegetarian children. Acta Paediatr Scand. 1985 Mar;74(2):191-5. doi: 10.1111/j.1651-2227.1985.tb10948.x. PMID: 3993364.
  91. Markestad T, Aksnes L, Ulstein M, Aarskog D. 25-Hydroxyvitamin D and 1,25-dihydroxyvitamin D of D2 and D3 origin in maternal and umbilical cord serum after vitamin D2 supplementation in human pregnancy. Am J Clin Nutr. 1984 Nov;40(5):1057-63. doi: 10.1093/ajcn/40.5.1057. PMID: 6333810.
  92. Markestad T, Ulstein M, Strandjord RE, Aksnes L, Aarskog D. Anticonvulsant drug therapy in human pregnancy: effects on serum concentrations of vitamin D metabolites in maternal and cord blood. Am J Obstet Gynecol. 1984 Oct 1;150(3):254-8. doi: 10.1016/s0002-9378(84)90361-2. PMID: 6091458.
  93. Markestad T, Aksnes L, Finne PH, Aarskog D. Effect of exchange transfusions with citrated blood on plasma concentrations of vitamin D metabolites in neonates. Pediatr Res. 1984 May;18(5):429-31. doi: 10.1203/00006450-198405000-00007. PMID: 6610165; PMCID: PMC7086570.
  94. Aarskog D, Aksnes L, Markestad T, Ulstein M, Sagen N. Heparin-induced inhibition of 1,25-dihydroxyvitamin D formation. Am J Obstet Gynecol. 1984 Apr 15;148(8):1141-2. doi: 10.1016/0002-9378(84)90644-6. PMID: 6711652.
  95. Markestad T, Aksnes L, Finne PH, Aarskog D. Plasma concentrations of vitamin D metabolites in premature infants. Pediatr Res. 1984 Mar;18(3):269-72. doi: 10.1203/00006450-198403000-00011. PMID: 6610164.
  96. Markestad T, Halvorsen S, Halvorsen KS, Aksnes L, Aarskog D. Plasma concentrations of vitamin D metabolites before and during treatment of vitamin D deficiency rickets in children. Acta Paediatr Scand. 1984 Mar;73(2):225-31. doi: 10.1111/j.1651-2227.1984.tb09933.x. PMID: 6331057.
  97. Markestad T, Elzouki A, Legnain M, Ulstein M, Aksnes L. Serum concentrations of vitamin D metabolites in maternal and umbilical cord blood of Libyan and Norwegian women. Hum Nutr Clin Nutr. 1984 Jan;38(1):55-62. PMID: 6607243.
  98. Markestad T, Kolmannskog S, Arntzen E, Toftegaard L, Haneberg B, Aksnes L. Serum concentrations of vitamin D metabolites in exclusively breast-fed infants at 70 degrees north. Acta Paediatr Scand. 1984 Jan;73(1):29-32. doi: 10.1111/j.1651-2227.1984.tb09893.x. PMID: 6546635.
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  102. Markestad T, Ulstein M, Bassoe HH, Aksnes L, Aarskog D. Vitamin D metabolism in normal and hypoparathyroid pregnancy and lactation. Case report. Br J Obstet Gynaecol. 1983 Oct;90(10):971-6. doi: 10.1111/j.1471-0528.1983.tb06774.x. PMID: 6626495.
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Respiratory Consequences of prematurity and early disease
  • Four regional Western Norway population based birth-cohorts who were born extremely preterm during 1982-85, 1991-1992, 1999-2000 and 2010-2018. Participants have regularly been brought in for testing, last time 2018-2019.
  • A nationwide population based cohort born extremely preterm during 1999-2000 has been followed with testing until the age of 5 years, since then by questionnaires.
  • A regional Western Norway population based birth cohort hospitalized for bronchiolitis during their first year of life during 1996 to 2001. The cohort has been followed since birth, last seen at age 17-20 years.

PhD dissertations:

 

Peer review publications:

  1. Bårdsen T, Satrell E, Drange Røksund O, Røineland Benestad M, Hufthammer KO, Clemm H, Bruun Mikalsen I, Øymar K, Halvorsen T, Vollsæter M. Lung function outcomes in adults born extremely preterm across three decades of advancing perinatal medicine. Acta Paediatr. 2024 Nov 22. doi: 10.1111/apa.17498. Epub ahead of print. PMID: 39575862.
  2. Vaula S, Øymar K, Hovland V, Matthews IL, Sachs-Strømmen C, Skjerven HO, Crowley S, Mikalsen IB. Trakeobronkomalasi hos barn. Tidsskr Nor Laegeforen. 2024 Oct 31;144(13). Norwegian. doi: 10.4045/tidsskr.24.0116. PMID: 39498651.
  3. Lillebøe HL, Engeset MS, Clemm HH, Halvorsen T, Røksund OD, Potrebny T, Vollsæter M. Expiratory airflow limitation in adults born extremely preterm: A systematic review and meta-analysis. Paediatr Respir Rev. 2024 Jun;50:2-22. doi: 10.1016/j.prrv.2024.02.002. Epub 2024 Feb 16. PMID: 38490917.
  4. Halvorsen T. Ambient Air Pollution and Morbidities in Bronchopulmonary Dysplasia; It's All about the Money. Ann Am Thorac Soc. 2024 Jan;21(1):34-36. doi: 10.1513/AnnalsATS.202310-893ED. PMID: 38156899; PMCID: PMC10867906.
  5. Hov B, Andersen T, Toussaint M, Mikalsen IB, Vollsæter M, Brunborg C, Hovde M, Hovland V. Mechanically assisted cough strategies: user perspectives and cough flows in children with neurodisability. ERJ Open Res. 2024 Jan 8;10(1):00274-2023. doi: 10.1183/23120541.00274-2023. PMID: 38196892; PMCID: PMC10772903.
  6. Simpson SJ, Du Berry C, Evans DJ, Gibbons JTD, Vollsæter M, Halvorsen T, Gruber K, Lombardi E, Stanojevic S, Hurst JR, Um-Bergström P, Hallberg J, Doyle LW, Kotecha S; PELICAN. Unravelling the respiratory health path across the lifespan for survivors of preterm birth. Lancet Respir Med. 2024 Feb;12(2):167-180. doi: 10.1016/S2213-2600(23)00272-2. Epub 2023 Nov 14. PMID: 37972623.
  7. Budal EB, Bentsen MHL, Kessler J, Ebbing C, Lindemann PC, Haugen OH, Aukland SM, Eide GE, Halvorsen T, Collett K. Histologic chorioamnionitis in extremely preterm births, microbiological findings and infant outcome. J Matern Fetal Neonatal Med. 2023 Dec;36(1):2196599. doi: 10.1080/14767058.2023.2196599. PMID: 37031964.
  8. Bårdsen T, Røksund OD, Eagan TML, Hufthammer KO, Benestad MR, Clemm HSH, Halvorsen T, Vollsæter M. Impaired Lung Function in Extremely Preterm-Born Adults in Their Fourth Decade of Life. Am J Respir Crit Care Med. 2023 Aug 15;208(4):493-495. doi: 10.1164/rccm.202303-0448LE. PMID: 37187173; PMCID: PMC10449077.
  9. Sørensen KG, Øymar K, Halvorsen T, Mikalsen IB. Blood eosinophils during bronchiolitis were not associated with adult asthma in a Norwegian cohort study. Acta Paediatr. 2023 May;112(5):1124-1125. doi: 10.1111/apa.16710. Epub 2023 Feb 23. PMID: 36794990.
  10. Hov B, Andersen T, Toussaint M, Mikalsen IB, Vollsaeter M, Markussen H, Indrekvam S, Hovland V. User-perceived impact of long-term mechanical assisted cough in paediatric neurodisability. Dev Med Child Neurol. 2023 May;65(5):655-663. doi: 10.1111/dmcn.15543. Epub 2023 Feb 14. PMID: 36787316.
  11. Sørensen KG, Øymar K, Jonsson G, Dalen I, Halvorsen T, Mikalsen IB. Are BMI and adipokines associated with asthma, atopy and lung function in young adults previously hospitalized for bronchiolitis? Respir Med. 2023 Apr;209:107149. doi: 10.1016/j.rmed.2023.107149. Epub 2023 Feb 6. PMID: 36754217.
  12. Sørensen KG, Øymar K, Dalen I, Halvorsen T, Bruun Mikalsen I. Blood eosinophils during bronchiolitis: Associations with atopy, asthma and lung function in young adults. Acta Paediatr. 2023 Apr;112(4):820-829. doi: 10.1111/apa.16666. Epub 2023 Jan 20. PMID: 36627486.
  13. Benestad MR, Drageset J, Hufthammer KO, Vollsæter M, Halvorsen T, Vederhus BJ. Long-term follow-up of self-reported mental health and health-related quality of life in adults born extremely preterm. Early Hum Dev. 2022 Oct;173:105661. doi: 10.1016/j.earlhumdev.2022.105661. Epub 2022 Aug 31. PMID: 36067714.
  14. Benestad MR, Drageset J, Eide GE, Vollsæter M, Halvorsen T, Vederhus BJ. Development of health-related quality of life and subjective health complaints in adults born extremely preterm: a longitudinal cohort study. Health Qual Life Outcomes. 2022 Jul 23;20(1):112. doi: 10.1186/s12955-022-02018-5. PMID: 35870980; PMCID: PMC9308198.
  15. Bårdsen T, Røksund OD, Benestad MR, Hufthammer KO, Clemm HH, Mikalsen IB, Øymar K, Markestad T, Halvorsen T, Vollsæter M. Tracking of lung function from 10 to 35 years after being born extremely preterm or with extremely low birth weight. Thorax. 2022 Aug;77(8):790-798. doi: 10.1136/thoraxjnl-2021-218400. Epub 2022 Apr 11. PMID: 35410959; PMCID: PMC9340024.
  16. Satrell E, Clemm H, Røksund OD, Hufthammer KO, Thorsen E, Halvorsen T, Vollsæter M. Development of lung diffusion to adulthood following extremely preterm birth. Eur Respir J. 2022 May 19;59(5):2004103. doi: 10.1183/13993003.04103-2020. PMID: 34625479; PMCID: PMC9117733.
  17. Budal EB, Ebbing C, Kessler J, Bains S, Haugen OH, Aukland SM, Eide GE, Halvorsen T, Bentsen MHL, Collett K. Placental histology predicted adverse outcomes in extremely premature neonates in Norway-population-based study. Acta Paediatr. 2022 Mar;111(3):546-553. doi: 10.1111/apa.16198. Epub 2021 Dec 6. PMID: 34825402.
  18. Engan M, Engeset MS, Sandvik L, Gamlemshaug OCO, Engesæter IØ, Øymar K, Vollsæter M, Røksund OD, Hufthammer KO, Halvorsen T, Clemm HH. Left Vocal Cord Paralysis, Lung Function and Exercise Capacity in Young Adults Born Extremely Preterm With a History of Neonatal Patent Ductus Arteriosus Surgery-A National Cohort Study. Front Pediatr. 2022 Jan 3;9:780045. doi: 10.3389/fped.2021.780045. PMID: 35047462; PMCID: PMC8761768.
  19. Sørensen KG, Øymar K, Dalen I, Halvorsen T, Mikalsen IB. Asthma, atopy and lung function in young adults after hospitalisation for bronchiolitis in infancy: impact of virus and sex. BMJ Open Respir Res. 2022 Jan;9(1):e001095. doi: 10.1136/bmjresp-2021-001095. PMID: 35046087; PMCID: PMC8772454.
  20. Hoareau L, Engelsen AST, Aanerud M, Ramnefjell MP, Salminen PR, Gärtner F, Halvorsen T, Raeder H, Bentsen MHL. Induction of alveolar and bronchiolar phenotypes in human lung organoids. Physiol Rep. 2021 Jun;9(11):e14857. doi: 10.14814/phy2.14857. PMID: 34110705; PMCID: PMC8191394.
  21. Andersen TM, Hov B, Halvorsen T, Røksund OD, Vollsæter M. Upper Airway Assessment and Responses During Mechanically Assisted Cough. Respir Care. 2021 Jul;66(7):1196-1213. doi: 10.4187/respcare.08960. Epub 2021 Feb 12. PMID: 33579747.
  22. Mikalsen IB, Halvorsen T, Juliusson PB, Magnus M, Nystad W, Stensrud T, Størdal K, Vollsæter M, Øymar K. Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age. Respir Med. 2021 Feb;177:106305. doi: 10.1016/j.rmed.2021.106305. Epub 2021 Jan 8. PMID: 33482491.
  23. Kuiper IN, Svanes C, Markevych I, Accordini S, Bertelsen RJ, Bråbäck L, Heile Christensen J, Forsberg B, Halvorsen T, Heinrich J, Hertel O, Hoek G, Holm M, de Hoogh K, Janson C, Malinovschi A, Marcon A, Miodini Nilsen R, Sigsgaard T, Johannessen A. Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood. Environ Int. 2021 Jan;146:106219. doi: 10.1016/j.envint.2020.106219. Epub 2020 Oct 27. PMID: 33126061.
  24. Sørensen KG, Mikalsen IB, Neven A, Øymar K. Half of children with recurrent or chronic wet cough before three years of age were symptom-free by age seven. Acta Paediatr. 2020 Dec;109(12):2664-2670. doi: 10.1111/apa.15293. Epub 2020 Apr 22. PMID: 32271955.
  25. Sautter M, Halvorsen T, Engan M, Clemm H, Bentsen MHL. Electromagnetic inductance plethysmography to study airflow after nebulized saline in bronchiolitis. Pediatr Pulmonol. 2020 Dec;55(12):3437-3442. doi: 10.1002/ppul.25058. Epub 2020 Sep 15. PMID: 32897652.
  26. Mikalsen IB, Byberg K, Forman MR, Øymar K. Adipokines in adolescence; the associations with lung function and atopy - A cross-sectional study. Respir Med. 2020 Aug-Sep;170:106063. doi: 10.1016/j.rmed.2020.106063. Epub 2020 Jun 15. PMID: 32705985.
  27. Kuiper IN, Markevych I, Accordini S, Bertelsen RJ, Bråbäck L, Christensen JH, Forsberg B, Halvorsen T, Heinrich J, Hertel O, Hoek G, Holm M, de Hoogh K, Janson C, Malinovschi A, Marcon A, Sigsgaard T, Svanes C, Johannessen A. Associations of Preconception Exposure to Air Pollution and Greenness with Offspring Asthma and Hay Fever. Int J Environ Res Public Health. 2020 Aug 12;17(16):5828. doi: 10.3390/ijerph17165828. PMID: 32806543; PMCID: PMC7459891.
  28. Sørensen KG, Øymar K, Halvorsen T, Mikalsen IB. Reply to Korppi and Riikonen. Pediatr Allergy Immunol. 2020 Aug;31(6):720-721. doi: 10.1111/pai.13272. Epub 2020 Jun 8. PMID: 32383494.
  29. Engan M, Engeseth MS, Fevang S, Vollsæter M, Eide GE, Røksund OD, Halvorsen T, Clemm H. Predicting physical activity in a national cohort of children born extremely preterm. Early Hum Dev. 2020 Jun;145:105037. doi: 10.1016/j.earlhumdev.2020.105037. Epub 2020 Apr 11. PMID: 32438296.
  30. Engeseth MS, Engan M, Clemm H, Vollsæter M, Nilsen RM, Markestad T, Halvorsen T, Røksund OD. Voice and Exercise Related Respiratory Symptoms in Extremely Preterm Born Children After Neonatal Patent Ductus Arteriosus. Front Pediatr. 2020 Apr 8;8:150. doi: 10.3389/fped.2020.00150. PMID: 32322565; PMCID: PMC7156623.
  31. Duijts L, van Meel ER, Moschino L, Baraldi E, Barnhoorn M, Bramer WM, Bolton CE, Boyd J, Buchvald F, Del Cerro MJ, Colin AA, Ersu R, Greenough A, Gremmen C, Halvorsen T, Kamphuis J, Kotecha S, Rooney-Otero K, Schulzke S, Wilson A, Rigau D, Morgan RL, Tonia T, Roehr CC, Pijnenburg MW. European Respiratory Society guideline on long-term management of children with bronchopulmonary dysplasia. Eur Respir J. 2020 Jan 2;55(1):1900788. doi: 10.1183/13993003.00788-2019. PMID: 31558663.
  32. Sørensen KG, Øymar K, Dalen I, Halvorsen T, Mikalsen IB. Lung function and bronchial hyper-reactivity from 11 to 18 years in children with bronchiolitis in infancy. Pediatr Allergy Immunol. 2020 Jan;31(1):57-65. doi: 10.1111/pai.13137. Epub 2019 Oct 25. Erratum in: Pediatr Allergy Immunol. 2022 Dec;33(12): PMID: 31595542.
  33. Engan M, Vollsæter M, Øymar K, Markestad T, Eide GE, Halvorsen T, Juliusson P, Clemm H. Comparison of physical activity and body composition in a cohort of children born extremely preterm or with extremely low birth weight to matched term-born controls: a follow-up study. BMJ Paediatr Open. 2019 Jun 29;3(1):e000481. doi: 10.1136/bmjpo-2019-000481. PMID: 31338430; PMCID: PMC6613845.
  34. Doyle LW, Andersson S, Bush A, Cheong JLY, Clemm H, Evensen KAI, Gough A, Halvorsen T, Hovi P, Kajantie E, Lee KJ, McGarvey L, Narang I, Näsänen-Gilmore P, Steinshamn S, Vollsaeter M, Vrijlandt EJLE; Adults born Preterm International Collaboration. Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data. Lancet Respir Med. 2019 Aug;7(8):677-686. doi: 10.1016/S2213-2600(18)30530-7. Epub 2019 May 8. PMID: 31078498.
  35. Mikalsen IB, Dalen I, Karlstad Ø, Eide GE, Magnus M, Nystad W, Øymar K. Airway symptoms and atopy in young children prescribed asthma medications: A large-scale cohort study. Pediatr Pulmonol. 2019 Oct;54(10):1557-1566. doi: 10.1002/ppul.24437. Epub 2019 Jul 4. PMID: 31273956.
  36. Mikalsen IB, Nassehi D, Øymar K. Vortex Whistle and Smart Phone Application for Peak Flow Recordings in Asthmatic Children: A Feasibility Study. Telemed J E Health. 2019 Nov;25(11):1077-1082. doi: 10.1089/tmj.2018.0270. Epub 2018 Dec 20. PMID: 30570372; PMCID: PMC6842893.
  37. Halvorsen T. Our Tiny Preemies: What Will Become of Their Future Pulmonary Health? Ann Am Thorac Soc. 2018 Nov;15(11):1276-1278. doi: 10.1513/AnnalsATS.201808-579ED. PMID: 30382787.
  38. Kotecha S, Clemm H, Halvorsen T, Kotecha SJ. Bronchial hyper-responsiveness in preterm-born subjects: A systematic review and meta-analysis. Pediatr Allergy Immunol. 2018 Nov;29(7):715-725. doi: 10.1111/pai.12957. Epub 2018 Sep 5. PMID: 30014518.
  39. Hestnes J, Hoel H, Risa OJ, Romstøl HO, Røksund O, Frisk B, Thorsen E, Halvorsen T, Clemm HH. Ventilatory Efficiency in Children and Adolescents Born Extremely Preterm. Front Physiol. 2017 Jul 13;8:499. doi: 10.3389/fphys.2017.00499. PMID: 28751866; PMCID: PMC5508024.
  40. Skromme K, Vollsæter M, Øymar K, Markestad T, Halvorsen T. Respiratory morbidity through the first decade of life in a national cohort of children born extremely preterm. BMC Pediatr. 2018 Mar 7;18(1):102. doi: 10.1186/s12887-018-1045-7. PMID: 29514655; PMCID: PMC5840932.
  41. Bentsen MH, Markestad T, Halvorsen T. Ventilator flow data predict bronchopulmonary dysplasia in extremely premature neonates. ERJ Open Res. 2018 Mar 13;4(1):00099-2017. doi: 10.1183/23120541.00099-2017. PMID: 29546045; PMCID: PMC5847811.
  42. Clemm HH, Engeseth M, Vollsæter M, Kotecha S, Halvorsen T. Bronchial hyper-responsiveness after preterm birth. Paediatr Respir Rev. 2018 Mar;26:34-40. doi: 10.1016/j.prrv.2017.06.010. Epub 2017 Jun 20. PMID: 28709779.
  43. Byberg KK, Mikalsen IB, Eide GE, Forman MR, Júlíusson PB, Øymar K. The associations between weight-related anthropometrics during childhood and lung function in late childhood: a retrospective cohort study. BMC Pulm Med. 2018 Jan 19;18(1):10. doi: 10.1186/s12890-017-0567-3. PMID: 29351745; PMCID: PMC5775530.
  44. Øymar K, Mikalsen IB, Crowley S. K. Øymar og medarbeidere svarer. Tidsskr Nor Laegeforen. 2018 Jan 8;138(1). Norwegian. doi: 10.4045/tidsskr.17.1089. PMID: 29313607.
  45. Bentsen MH, Markestad T, Øymar K, Halvorsen T. Lung function at term in extremely preterm-born infants: a regional prospective cohort study. BMJ Open. 2017 Oct 25;7(10):e016868. doi: 10.1136/bmjopen-2017-016868. PMID: 29074512; PMCID: PMC5665228.
  46. Bentsen MH, Satrell E, Reigstad H, Johnsen SL, Vollsæter M, Røksund OD, Greve G, Berg A, Markestad T, Halvorsen T. Mid-childhood outcomes after pre-viable preterm premature rupture of membranes. J Perinatol. 2017 Sep;37(9):1053-1059. doi: 10.1038/jp.2017.97. Epub 2017 Jun 29. PMID: 28661513.
  47. Bjørke-Monsen AL, Vollsæter M, Ueland PM, Markestad T, Øymar K, Halvorsen T. Increased Bronchial Hyperresponsiveness and Higher Asymmetric Dimethylarginine Levels after Fetal Growth Restriction. Am J Respir Cell Mol Biol. 2017 Jan;56(1):83-89. doi: 10.1165/rcmb.2016-0210OC. PMID: 27574738.
  48. Bentsen MH, Eriksen M, Olsen MS, Markestad T, Halvorsen T. Electromagnetic inductance plethysmography is well suited to measure tidal breathing in infants. ERJ Open Res. 2016 Nov 24;2(4):00062-2016. doi: 10.1183/23120541.00062-2016. PMID: 28053968; PMCID: PMC5152798.
  49. Vollsæter M. Lungehelse etter ekstremt for tidlig fødsel. Tidsskr Nor Laegeforen. 2016 Sep 27;136(17):1475. Norwegian. doi: 10.4045/tidsskr.16.0643. PMID: 27686214.
  50. Clemm HS. Fysisk kapasitet hos ekstremt premature. Tidsskr Nor Laegeforen. 2016 Feb 23;136(4):340. Norwegian. doi: 10.4045/tidsskr.15.1325. PMID: 26905855.
  51. Vollsæter M, Skromme K, Satrell E, Clemm H, Røksund O, Øymar K, Markestad T, Halvorsen T. Children Born Preterm at the Turn of the Millennium Had Better Lung Function Than Children Born Similarly Preterm in the Early 1990s. PLoS One. 2015 Dec 7;10(12):e0144243. doi: 10.1371/journal.pone.0144243. PMID: 26641080; PMCID: PMC4671691.
  52. Mikalsen IB, Skeiseid L, Tveit LM, Engelsvold DH, Øymar K. Decline in admissions for childhood asthma, a 26-year period population-based study. Pediatr Allergy Immunol. 2015 Dec;26(8):750-5. doi: 10.1111/pai.12372. Epub 2015 May 7. PMID: 25787851.
  53. Bentsen MH, Haaland ØA, Lønning LB, Gudmundsdottir HK, Markestad T, Halvorsen T. A new non-invasive method of infant spirometry demonstrates a level of repeatability that is comparable to traditional methods. Acta Paediatr. 2015 Nov;104(11):1130-7. doi: 10.1111/apa.13155. PMID: 26287280.
  54. Clemm HH, Vollsaeter M, Røksund OD, Markestad T, Halvorsen T. Adolescents who were born extremely preterm demonstrate modest decreases in exercise capacity. Acta Paediatr. 2015 Nov;104(11):1174-81. doi: 10.1111/apa.13080. Epub 2015 Jul 28. PMID: 26096772.
  55. Skromme K, Leversen KT, Eide GE, Markestad T, Halvorsen T. Respiratory illness contributed significantly to morbidity in children born extremely premature or with extremely low birthweights in 1999-2000. Acta Paediatr. 2015 Nov;104(11):1189-98. doi: 10.1111/apa.13165. PMID: 26303868.
  56. Vollsæter M, Clemm HH, Satrell E, Eide GE, Røksund OD, Markestad T, Halvorsen T. Adult respiratory outcomes of extreme preterm birth. A regional cohort study. Ann Am Thorac Soc. 2015 Mar;12(3):313-22. doi: 10.1513/AnnalsATS.201406-285OC. PMID: 25616079.
  57. Clemm HH, Vollsæter M, Røksund OD, Eide GE, Markestad T, Halvorsen T. Exercise capacity after extremely preterm birth. Development from adolescence to adulthood. Ann Am Thorac Soc. 2014 May;11(4):537-45. doi: 10.1513/AnnalsATS.201309-311OC. PMID: 24502400.
  58. Øymar K, Bårdsen K. Continuous positive airway pressure for bronchiolitis in a general paediatric ward; a feasibility study. BMC Pediatr. 2014 May 12;14:122. doi: 10.1186/1471-2431-14-122. PMID: 24886569; PMCID: PMC4020573.
  59. Øymar K, Skjerven HO, Mikalsen IB. Acute bronchiolitis in infants, a review. Scand J Trauma Resusc Emerg Med. 2014 Apr 3;22:23. doi: 10.1186/1757-7241-22-23. PMID: 24694087; PMCID: PMC4230018.
  60. Mikalsen IB, Halvorsen T, Øymar K. Blood eosinophil counts during bronchiolitis are related to bronchial hyper-responsiveness and lung function in early adolescence. Acta Paediatr. 2014 Jan;103(1):86-92. doi: 10.1111/apa.12432. Epub 2013 Nov 11. PMID: 24117779.
  61. Satrell E, Røksund O, Thorsen E, Halvorsen T. Pulmonary gas transfer in children and adolescents born extremely preterm. Eur Respir J. 2013 Dec;42(6):1536-44. doi: 10.1183/09031936.00027112. Epub 2012 Nov 22. PMID: 23180590.
  62. Mikalsen IB, Halvorsen T, Eide GE, Øymar K. Severe bronchiolitis in infancy: can asthma in adolescence be predicted? Pediatr Pulmonol. 2013 Jun;48(6):538-44. doi: 10.1002/ppul.22675. Epub 2012 Sep 13. PMID: 22976850.
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Inducible laryngeal obstruction and sports

PhD dissertations:

Peer review publications:

  1. Vreim K, Karlsen T, Carlsen PH, Nistad VH, Røksund OD, Halvorsen T, Vollsæter M, Heimdal JH, Clemm H, Engan M. Speech therapy for exercise-induced laryngeal obstruction. Eur Arch Otorhinolaryngol. 2025 Mar;282(3):1345-1354. doi: 10.1007/s00405-024-09190-y. Epub 2025 Jan 21. PMID: 39836184; PMCID: PMC11890322.
  2. Fitzgerald HT, Halvorsen T, Engan M, Li S, Selvadurai H. Exercise capacity and the psychosocial effect in preterm born infants - Should we do more? Paediatr Respir Rev. 2025 Jan 8:S1526-0542(25)00002-8. doi: 10.1016/j.prrv.2025.01.001. Epub ahead of print. PMID: 39863457.
  3. Brekka AK, Ntoumenopoulos G, Røksund OD, Engeset MS, Clemm H, Halvorsen T, Vollsæter M, Andersen T. Use of Laryngeal Ultrasound to Observe Laryngeal Movements During Noninvasive Ventilation in Healthy Volunteers. Respir Care. 2025 Mar;70(3):249-257. doi: 10.4187/respcare.12201. Epub 2024 Oct 29. PMID: 39472069.
  4. Christen A, O'Connell A, Mayer I, Tona G, Hilland M, Clemm H. Understanding Speech-Language Pathology and Surgical Interventions for Exercise-Induced Laryngeal Obstruction. Immunol Allergy Clin North Am. 2025 Feb;45(1):29-38. doi: 10.1016/j.iac.2024.09.002. Epub 2024 Oct 24. PMID: 39608877.
  5. Andersen TM, Brekka AK, Fretheim-Kelly Z, Lujan M, Heimdal JH, Clemm HH, Halvorsen T, Fondenes O, Nilsen RM, Røksund OD, Vollsæter M. Upper Airway and Translaryngeal Resistance During Mechanical Insufflation-Exsufflation. Chest. 2025 Jan;167(1):188-201. doi: 10.1016/j.chest.2024.08.022. Epub 2024 Aug 26. PMID: 39197511.
  6. Hull JH, Clemm H, Backer V, Koehle M, Mountjoy M, Schwellnus M, Olin JT. Protecting respiratory health of athletes: an Olympic challenge. Lancet Respir Med. 2024 Jul;12(7):509-510. doi: 10.1016/S2213-2600(24)00183-8. Epub 2024 Jun 5. PMID: 38851194.
  7. Karlsen T, Vreim K, Røksund OD, Vollsæter M, Muralitharan P, Ellingsen TA, Heimdal JH, Halvorsen T, Clemm H. A speech therapy treatment protocol for exercise induced laryngeal obstruction. Front Pediatr. 2024 Jun 13;12:1356476. doi: 10.3389/fped.2024.1356476. PMID: 38938504; PMCID: PMC11208626.
  8. Carlsen PH, Muralitharan P, Fenne H, Hammer IJ, Engan M, Vollsæter M, Bovim LP, Røksund OD, Halvorsen T, Clemm HH. Laryngeal response to high-intensity exercise in healthy athletes. BMJ Open Sport Exerc Med. 2024 May 20;10(2):e001850. doi: 10.1136/bmjsem-2023-001850. PMID: 38779574; PMCID: PMC11110563.
  9. Vollsæter M, Veierød SS, Sveen HH, Røksund OD, Moi AL, Jorem GT, Beisland EG. When Art Meets Medicine: Use of Flexible Laryngoscopy in Development of Singers' Voices-A Scoping Review. J Voice. 2024 Mar 28:S0892-1997(24)00066-3. doi: 10.1016/j.jvoice.2024.02.029. Epub ahead of print. PMID: 38553319.
  10. Leong P, Hull JH, Gibson PG, Halvorsen T, Bardin PG; VCD/ILO Delphi Steering Committee. Reply. J Allergy Clin Immunol. 2023 Dec;152(6):1688-1689. doi: 10.1016/j.jaci.2023.08.027. Epub 2023 Sep 20. PMID: 37737751.
  11. Leong P, Vertigan AE, Hew M, Baxter M, Phyland D, Hull JH, Carroll TL, Gibson PG, McDonald VM, Halvorsen T, Clemm HH, Vollsæter M, Røksund OD, Bardin PG; Vocal Cord Dysfunction/Inducible Laryngeal Obstruction Delphi Expert Panel. Diagnosis of vocal cord dysfunction/inducible laryngeal obstruction: An International Delphi Consensus Study. J Allergy Clin Immunol. 2023 Oct;152(4):899-906. doi: 10.1016/j.jaci.2023.06.007. Epub 2023 Jun 20. PMID: 37343843.
  12. Leong P, Hull JH, Gibson PG, Halvorsen T, Bardin PG; VCD/ILO Delphi Steering Committee. Reply. J Allergy Clin Immunol. 2023 Sep 20:S0091-6749(23)01111-9. doi: 10.1016/j.jaci.2023.08.027. Epub ahead of print. PMID: 37737751.
  13. Leong P, Vertigan AE, Hew M, Baxter M, Phyland D, Hull JH, Carroll TL, Gibson PG, McDonald VM, Halvorsen T, Clemm HH, Vollsæter M, Røksund OD, Bardin PG; Vocal Cord Dysfunction/Inducible Laryngeal Obstruction Delphi Expert Panel. Diagnosis of vocal cord dysfunction/inducible laryngeal obstruction: An International Delphi Consensus Study. J Allergy Clin Immunol. 2023 Oct;152(4):899-906. doi: 10.1016/j.jaci.2023.06.007. Epub 2023 Jun 20. PMID: 37343843.
  14. Rogde ÅJ, Lehmann S, Halvorsen T, Clemm HH, Røksund OD, Hufthammer KO, Kvidaland HK, Vollsæter M, Andersen TM. Prevalence and impact of exercise-induced laryngeal obstruction in asthma: a study protocol for a cross-sectional and longitudinal study. BMJ Open. 2023 Jun 16;13(6):e071159. doi: 10.1136/bmjopen-2022-071159. PMID: 37328176; PMCID: PMC10277068.
  15. Fretheim-Kelly Z, Clemm HSH, Røksund OD, Hilland M, Vollsæter M, Halvorsen T. Translaryngeal Resistance: A Measurement to Assist Decision Making in Upper Airway Pathology. Am J Respir Crit Care Med. 2023 Sep 15;208(6):e32-e34. doi: 10.1164/rccm.202205-0961IM. PMID: 37219897.
  16. Bernhardsen GP, Stang J, Halvorsen T, Stensrud T. Differences in lung function, bronchial hyperresponsiveness and respiratory health between elite athletes competing in different sports. Eur J Sport Sci. 2023 Aug;23(8):1480-1489. doi: 10.1080/17461391.2022.2113144. Epub 2022 Aug 31. PMID: 35975407.
  17. Clemm HSH. Letter from Norway. Respirology. 2023 May;28(5):500-501. doi: 10.1111/resp.14478. Epub 2023 Mar 7. PMID: 36882379.
  18. Muralitharan P, Carlsen P, Hilland M, Delestre-Levai I, Vollsæter M, Hufthammer KO, Engan M, Røksund OD, Halvorsen T, Clemm HH. Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended. ERJ Open Res. 2023 Jan 23;9(1):00308-2022. doi: 10.1183/23120541.00308-2022. PMID: 36699648; PMCID: PMC9868967.
  19. Kvidaland H, Stadheim S, Bø S, Clemm H, Røksund OD, Vollsæter M, Hardie J. Is it feasible to perform a continuous laryngoscopy exercise test with a cold air inhalate? A case report. ERJ Open Res. 2022 Nov 28;8(4):00222-2022. doi: 10.1183/23120541.00222-2022. PMID: 36451846; PMCID: PMC9703141.
  20. Gundersen H, Riiser A, Algroy E, Vestbøstad M, Saeterbakken AH, Clemm HH, Grendstad H, Hafstad A, Kristoffersen M, Rygh CB. Associations between biological maturity level, match locomotion, and physical capacities in youth male soccer players. Scand J Med Sci Sports. 2022 Nov;32(11):1592-1601. doi: 10.1111/sms.14225. Epub 2022 Aug 30. PMID: 36004501; PMCID: PMC9804799.
  21. Andersen TM, Vollsæter M. Go With the Flow: Are We Cracking the Code? Respiratory Management of Bulbar ALS Is Evolving. Respir Care. 2022 Oct;67(10):1363-1365. doi: 10.4187/respcare.10487. PMID: 36137578.
  22. Schwellnus M, Adami PE, Bougault V, Budgett R, Clemm HH, Derman W, Erdener U, Fitch K, Hull JH, McIntosh C, Meyer T, Pedersen L, Pyne DB, Reier-Nilsen T, Schobersberger W, Schumacher YO, Sewry N, Soligard T, Valtonen M, Webborn N, Engebretsen L. International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 1: acute respiratory infections. Br J Sports Med. 2022 Jul 21:bjsports-2022-105759. doi: 10.1136/bjsports-2022-105759. Epub ahead of print. PMID: 35863871.
  23. Clemm HH, Olin JT, McIntosh C, Schwellnus M, Sewry N, Hull JH, Halvorsen T. Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'. Br J Sports Med. 2022 Jun;56(11):622-629. doi: 10.1136/bjsports-2021-104704. Epub 2022 Feb 22. PMID: 35193856; PMCID: PMC9120388
  24. Schwellnus M, Adami PE, Bougault V, Budgett R, Clemm HH, Derman W, Erdener U, Fitch K, Hull JH, McIntosh C, Meyer T, Pedersen L, Pyne DB, Reier-Nilsen T, Schobersberger W, Schumacher YO, Sewry N, Soligard T, Valtonen M, Webborn N, Engebretsen L. International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 2: non-infective acute respiratory illness. Br J Sports Med. 2022 May 27:bjsports-2022-105567. doi: 10.1136/bjsports-2022-105567. Epub ahead of print. PMID: 35623888.
  25. Brekka AK, Vollsæter M, Ntoumenopoulos G, Clemm HH, Halvorsen T, Røksund OD, Andersen TM. Adjustments of non-invasive ventilation and mechanically assisted cough by combining ultrasound imaging of the larynx with transnasal fibre-optic laryngoscopy: a protocol for an experimental study. BMJ Open. 2022 May 25;12(5):e059234. doi: 10.1136/bmjopen-2021-059234. PMID: 35613803; PMCID: PMC9134209.
  26. Andersen T, Fondenes O, Røksund OD, Clemm H, Halvorsen T, Vollsæter M. From bedside to bench - In vivo and in vitro evaluation of mechanically assisted cough treatment in a patient with bulbar Amyotrophic Lateral Sclerosis. Respir Med Case Rep. 2022 Apr 9;37:101649. doi: 10.1016/j.rmcr.2022.101649. PMID: 35480384; PMCID: PMC9035434.
  27. Fretheim-Kelly Z, Engan M, Clemm H, Andersen T, Heimdal JH, Strand E, Halvorsen T, Røksund O, Vollsæter M. Reliability of translaryngeal airway resistance measurements during maximal exercise. ERJ Open Res. 2022 Mar 14;8(1):00581-2021. doi: 10.1183/23120541.00581-2021. PMID: 35309036; PMCID: PMC8923134.
  28. Halvorsen T, Røksund O. A novel validated tool to score symptom burden in exercise-induced laryngeal obstruction: can we simplify patient follow-up and research? Lancet Respir Med. 2022 Feb;10(2):131-132. doi: 10.1016/S2213-2600(22)00019-4. PMID: 35120607.
  29. Clemm H, Røksund OD, Andersen T, Heimdal JH, Karlsen T, Hilland M, Fretheim-Kelly Z, Hufthammer KO, Sandnes A, Hjelle S, Vollsæter M, Halvorsen T; Bergen ILO-group. Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial. Front Pediatr. 2022 Feb 7;10:817003. doi: 10.3389/fped.2022.817003. PMID: 35198517; PMCID: PMC8858975.
  30. Olin JT, Fredericson M, Nichol C, Willick SE, Clemm HH; Tokyo 2020 Isolation Hotel medical support team. Lessons learned from the Tokyo games isolation hotel experience. Br J Sports Med. 2022 Jun;56(11):597-598. doi: 10.1136/bjsports-2021-105116. Epub 2022 Feb 11. PMID: 35149511.
  31. Jansrud Hammer I, Halvorsen T, Vollsaeter M, Hilland M, Heimdal JH, Røksund OD, Clemm HH. Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma? Scand J Med Sci Sports. 2022 Jun;32(6):1041-1049. doi: 10.1111/sms.14137. Epub 2022 Feb 8. PMID: 35114031; PMCID: PMC9303344.
  32. Vollsæter M, Stensrud T, Maat R, Halvorsen T, Røksund OD, Sandnes A, Clemm H. Exercise Related Respiratory Problems in the Young-Is It Exercise-Induced Bronchoconstriction or Laryngeal Obstruction? Front Pediatr. 2022 Jan 3;9:800073. doi: 10.3389/fped.2021.800073. PMID: 35047465; PMCID: PMC8762363.
  33. Sandnes A, Andersen T, Clemm HH, Hilland M, Heimdal JH, Halvorsen T, Røksund OD, Vollsæter M. Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction. Eur Arch Otorhinolaryngol. 2022 May;279(5):2511-2522. doi: 10.1007/s00405-021-07214-5. Epub 2021 Dec 26. PMID: 34954812; PMCID: PMC8986676.
  34. Hammer S, Toussaint M, Vollsæter M, Nesbjørg Tvedt M, Drange Røksund O, Reychler G, Lund H, Andersen T. Exercise Training in Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis. J Rehabil Med. 2022 Jan 11;54:jrm00250. doi: 10.2340/jrm.v53.985. PMID: 35642324; PMCID: PMC8862644.
  35. Lie AH, Grønnevik I, Frisk B, Røksund OD, Hammer I, Vollsaeter M, Halvorsen T, Clemm HH. Breathing patterns in people with exercise-induced laryngeal obstruction. Physiol Rep. 2021 Nov;9(22):e15086. doi: 10.14814/phy2.15086. PMID: 34822227; PMCID: PMC8613803.
  36. Benestad MR, Drageset J, Clemm H, Røksund OD, Vollsæter M, Halvorsen T, Hysing M, Vederhus BJ. Self-Reported Health in Adolescents With Exercise-Induced Laryngeal Obstruction; A Cross-Sectional Study. Front Pediatr. 2021 Jul 8;9:617759. doi: 10.3389/fped.2021.617759. PMID: 34307244; PMCID: PMC8295467.
  37. McIntosh C, Clemm HH, Sewry N, Hrubos-Strøm H, Schwellnus MP. Diagnosis and management of nasal obstruction in the athlete. A narrative review by subgroup B of the IOC Consensus Group on "Acute Respiratory Illness in the Athlete". J Sports Med Phys Fitness. 2021 Aug;61(8):1144-1158. doi: 10.23736/S0022-4707.21.12821-X. Epub 2021 Jun 22. PMID: 34156184.
  38. Engan M, Hammer IJ, Bekken M, Halvorsen T, Fretheim-Kelly ZL, Vollsæter M, Bovim LPV, Røksund OD, Clemm H. Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy. ERJ Open Res. 2021 Feb 15;7(1):00825-2020. doi: 10.1183/23120541.00825-2020. PMID: 33614778; PMCID: PMC7882785.
  39. Engan M, Hammer IJ, Stensrud T, Gundersen H, Edvardsen E, Clemm HH. Changes in pulmonary function and feasibility of portable continuous laryngoscopy during maximal uphill running. BMJ Open Sport Exerc Med. 2020 Aug 24;6(1):e000815. doi: 10.1136/bmjsem-2020-000815. PMID: 33403123; PMCID: PMC7772557.
  40. Halvorsen T, Clemm HSH, Vollsæter M, Røksund OD. Conundrums of Exercise-related Breathing Problems. Epiglottic, Laryngeal, or Bronchial Obstruction? Am J Respir Crit Care Med. 2020 Nov 15;202(10):e142-e143. doi: 10.1164/rccm.201910-1921IM. PMID: 32783778.
  41. Fretheim-Kelly Z, Halvorsen T, Heimdal JH, Strand E, Vollsaeter M, Clemm H, Roksund O. Feasibility and tolerability of measuring translaryngeal pressure during exercise. Laryngoscope. 2019 Dec;129(12):2748-2753. doi: 10.1002/lary.27846. Epub 2019 Jan 30. PMID: 30698834; PMCID: PMC6900056.
  42. Fretheim-Kelly ZL, Halvorsen T, Clemm H, Roksund O, Heimdal JH, Vollsæter M, Fintl C, Strand E. Exercise Induced Laryngeal Obstruction in Humans and Equines. A Comparative Review. Front Physiol. 2019 Oct 30;10:1333. doi: 10.3389/fphys.2019.01333. PMID: 31736771; PMCID: PMC6831747.
  43. Sandnes A, Hilland M, Vollsæter M, Andersen T, Engesæter IØ, Sandvik L, Heimdal JH, Halvorsen T, Eide GE, Røksund OD, Clemm HH. Severe Exercise-Induced Laryngeal Obstruction Treated With Supraglottoplasty. Front Surg. 2019 Jul 31;6:44. doi: 10.3389/fsurg.2019.00044. PMID: 31417908; PMCID: PMC6684966.
  44. Andersen TM, Halvorsen T, Fondenes O, Heimdal JH, Røksund OD, Vollsæter M, Røksund OD. Larynx: The Complex Gateway to the Lungs. Respir Care. 2019 Jul;64(7):866-869. doi: 10.4187/respcare.06989. PMID: 31243162.
  45. Sandnes A, Andersen T, Clemm HH, Hilland M, Vollsæter M, Heimdal JH, Eide GE, Halvorsen T, Røksund OD. Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training. BMJ Open Sport Exerc Med. 2019 Jan 18;5(1):e000436. doi: 10.1136/bmjsem-2018-000436. PMID: 30792880; PMCID: PMC6350751.
  46. Kolnes LJ, Vollsæter M, Røksund OD, Stensrud T. Physiotherapy improves symptoms of exercise-induced laryngeal obstruction in young elite athletes: a case series. BMJ Open Sport Exerc Med. 2019 Jan 23;5(1):e000487. doi: 10.1136/bmjsem-2018-000487. PMID: 30740235; PMCID: PMC6347884.
  47. Andersen TM, Sandnes A, Fondenes O, Clemm H, Halvorsen T, Nilsen RM, Tysnes OB, Heimdal JH, Vollsæter M, Røksund OD. Laryngoscopy Can Be a Valuable Tool for Unexpected Therapeutic Response in Noninvasive Respiratory Interventions. Respir Care. 2018 Nov;63(11):1459-1461. doi: 10.4187/respcare.06674. PMID: 30389835.
  48. Engeseth MS, Olsen NR, Maeland S, Halvorsen T, Goode A, Røksund OD. Left vocal cord paralysis after patent ductus arteriosus ligation: A systematic review. Paediatr Respir Rev. 2018 Jun;27:74-85. doi: 10.1016/j.prrv.2017.11.001. Epub 2017 Nov 15. PMID: 29336933.
  49. Røksund OD, Olin JT, Halvorsen T. Working Towards a Common Transatlantic Approach for Evaluation of Exercise-Induced Laryngeal Obstruction. Immunol Allergy Clin North Am. 2018 May;38(2):281-292. doi: 10.1016/j.iac.2018.01.002. Epub 2018 Feb 19. PMID: 29631736.
  50. Andersen TM, Sandnes A, Fondenes O, Nilsen RM, Tysnes OB, Heimdal JH, Clemm HH, Halvorsen T, Vollsæter M, Røksund OD. Laryngeal Responses to Mechanically Assisted Cough in Progressing Amyotrophic Lateral Sclerosis. Respir Care. 2018 May;63(5):538-549. doi: 10.4187/respcare.05924. Epub 2018 Apr 17. PMID: 29666294.
  51. Clemm HSH, Sandnes A, Vollsæter M, Hilland M, Heimdal JH, Røksund OD, Halvorsen T. The Heterogeneity of Exercise-induced Laryngeal Obstruction. Am J Respir Crit Care Med. 2018 Apr 15;197(8):1068-1069. doi: 10.1164/rccm.201708-1646IM. PMID: 29390192.
  52. Halvorsen T, Walsted ES, Bucca C, Bush A, Cantarella G, Friedrich G, Herth FJF, Hull JH, Jung H, Maat R, Nordang L, Remacle M, Rasmussen N, Wilson JA, Heimdal JH. Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement. Eur Respir J. 2017 Sep 9;50(3):1602221. doi: 10.1183/13993003.02221-2016. PMID: 28889105.
  53. Andersen T, Sandnes A, Brekka AK, Hilland M, Clemm H, Fondenes O, Tysnes OB, Heimdal JH, Halvorsen T, Vollsæter M, Røksund OD. Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis. Thorax. 2017 Mar;72(3):221-229. doi: 10.1136/thoraxjnl-2015-207555. Epub 2016 May 12. PMID: 27174631; PMCID: PMC5339574.
  54. Hilland M, Røksund OD, Sandvik L, Haaland Ø, Aarstad HJ, Halvorsen T, Heimdal JH. Congenital laryngomalacia is related to exercise-induced laryngeal obstruction in adolescence. Arch Dis Child. 2016 May;101(5):443-8. doi: 10.1136/archdischild-2015-308450. Epub 2016 Feb 23. PMID: 26906070; PMCID: PMC4853585.
  55. Norlander K, Christensen PM, Maat RC, Halvorsen T, Heimdal JH, Morén S, Rasmussen N, Nordang L. Comparison between two assessment methods for exercise-induced laryngeal obstructions. Eur Arch Otorhinolaryngol. 2016 Feb;273(2):425-30. doi: 10.1007/s00405-015-3758-7. Epub 2015 Sep 8. PMID: 26351037.
  56. Røksund OD, Heimdal JH, Clemm H, Vollsæter M, Halvorsen T. Exercise inducible laryngeal obstruction: diagnostics and management. Paediatr Respir Rev. 2017 Jan;21:86-94. doi: 10.1016/j.prrv.2016.07.003. Epub 2016 Jul 18. PMID: 27492717.
  57. Christensen PM, Heimdal JH, Christopher KL, Bucca C, Cantarella G, Friedrich G, Halvorsen T, Herth F, Jung H, Morris MJ, Remacle M, Rasmussen N, Wilson JA; ERS/ELS/ACCP Task Force on Inducible Laryngeal Obstructions. ERS/ELS/ACCP 2013 international consensus conference nomenclature on inducible laryngeal obstructions. Eur Respir Rev. 2015 Sep;24(137):445-50. doi: 10.1183/16000617.00006513. PMID: 26324806; PMCID: PMC9487687.
  58. Røksund OD, Heimdal JH, Olofsson J, Maat RC, Halvorsen T. Larynx during exercise: the unexplored bottleneck of the airways. Eur Arch Otorhinolaryngol. 2015 Sep;272(9):2101-9. doi: 10.1007/s00405-014-3159-3. Epub 2014 Jul 18. PMID: 25033930; PMCID: PMC4526593.
  59. Andersen T, Sandnes A, Hilland M, Halvorsen T, Fondenes O, Heimdal JH, Tysnes OB, Røksund OD. Laryngeal response patterns to mechanical insufflation-exsufflation in healthy subjects. Am J Phys Med Rehabil. 2013 Oct;92(10):920-9. doi: 10.1097/PHM.0b013e3182a4708f. PMID: 24051994.
  60. Sandnes A, Andersen T, Hilland M, Ellingsen TA, Halvorsen T, Heimdal JH, Røksund OD. Laryngeal movements during inspiratory muscle training in healthy subjects. J Voice. 2013 Jul;27(4):448-53. doi: 10.1016/j.jvoice.2013.02.010. Epub 2013 May 15. PMID: 23683807.
  61. Maat RC, Hilland M, Røksund OD, Halvorsen T, Olofsson J, Aarstad HJ, Heimdal JH. Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment. Eur Arch Otorhinolaryngol. 2011 Oct;268(10):1485-92. doi: 10.1007/s00405-011-1656-1. Epub 2011 Jun 5. PMID: 21643933; PMCID: PMC3166603.
  62. Halvorsen T, Røksund OD, Maat RC, Heimdal JH. In reference to: "Use of post-exercise laryngoscopy to evaluate exercise induced dyspnea" Pediatric Pulmonol, 2010; 45: 1037-1039. Pediatr Pulmonol. 2011 May;46(5):515-6. doi: 10.1002/ppul.21431. Epub 2011 Feb 17. PMID: 21337532.
  63. Røksund OD, Clemm H, Heimdal JH, Aukland SM, Sandvik L, Markestad T, Halvorsen T. Left vocal cord paralysis after extreme preterm birth, a new clinical scenario in adults. Pediatrics. 2010 Dec;126(6):e1569-77. doi: 10.1542/peds.2010-1129. Epub 2010 Nov 22. PMID: 21098147.
  64. Røksund OD, Maat RC, Heimdal JH, Olofsson J, Skadberg BT, Halvorsen T. Exercise induced dyspnea in the young. Larynx as the bottleneck of the airways. Respir Med. 2009 Dec;103(12):1911-8. doi: 10.1016/j.rmed.2009.05.024. Epub 2009 Sep 26. PMID: 19782550.
  65. Maat RC, Røksund OD, Halvorsen T, Skadberg BT, Olofsson J, Ellingsen TA, Aarstad HJ, Heimdal JH. Audiovisual assessment of exercise-induced laryngeal obstruction: reliability and validity of observations. Eur Arch Otorhinolaryngol. 2009 Dec;266(12):1929-36. doi: 10.1007/s00405-009-1030-8. Epub 2009 Jul 8. PMID: 19585139.
  66. Maat RC, Røksund OD, Olofsson J, Halvorsen T, Skadberg BT, Heimdal JH. Surgical treatment of exercise-induced laryngeal dysfunction. Eur Arch Otorhinolaryngol. 2007 Apr;264(4):401-7. doi: 10.1007/s00405-006-0216-6. Epub 2007 Jan 4. PMID: 17203312.
  67. Heimdal JH, Røksund OD, Halvorsen T, Skadberg BT, Olofsson J. Continuous laryngoscopy exercise test: a method for visualizing laryngeal dysfunction during exercise. Laryngoscope. 2006 Jan;116(1):52-7. doi: 10.1097/01.mlg.0000184528.16229.ba. PMID: 16481809.
Kidney disease early in life
  • GFR methodology; multipoint iohexol clearance and simplified methods to evaluate kidney function in children.
  • Consequences of prematurity and low birth weight on kidney function
  • Kidney biopsies - structural findings and transcriptomics
  • Urinary tract infections in childhood
  • The Renal Research Group | University of Bergen (uib.no)

PhD dissertations:

Peer review publications:

  1. Prytula A, Shroff R, van Gremberghe I, Krupka K, Bacchetta J, Benetti E, Grenda R, Guzzo I, Kanzelmeyer N, Büyükkaragöz B, Kranz B, Nalçacıoğlu H, Oh J, Pape L, Shenoy M, Sellier-Leclerc AL, Tönshoff B; European Society for Paediatric Nephrology Transplantation and CKD-MBD working groups and the Cooperative European Paediatric Renal Transplant Initiative Research Network. Metabolic Acidosis Is Associated With an Accelerated Decline of Allograft Function in Pediatric Kidney Transplantation. Kidney Int Rep. 2024 Apr 8;9(6):1684-1693. doi: 10.1016/j.ekir.2024.04.007. PMID: 38899185; PMCID: PMC11184248.
  2. Smerkous D, Mauer M, Tøndel C, Svarstad E, Gubler MC, Nelson RG, Oliveira JP, Sargolzaeiaval F, Najafian B. Development of an automated estimation of foot process width using deep learning in kidney biopsies from patients with Fabry, minimal change, and diabetic kidney diseases. Kidney Int. 2023 Sep 27:S0085-2538(23)00675-0. doi: 10.1016/j.kint.2023.09.011. Epub ahead of print. PMID: 37774924.
  3. Elsaid HOA, Rivedal M, Skandalou E, Svarstad E, Tøndel C, Birkeland E, Eikrem Ø, Babickova J, Marti HP, Furriol J. Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla-/- zebrafish model of Fabry disease. J Transl Med. 2023 Sep 5;21(1):591. doi: 10.1186/s12967-023-04475-y. PMID: 37670295; PMCID: PMC10478213.
  4. Salvador CL, Flemmen PTK, Tøndel C, Bliksrud YT, Tsui EFF, Brun A, Bjerre A, Mørkrid L. Renal function, sex and age influence purines and pyrimidines in urine and could lead to diagnostic misinterpretation. Mol Genet Metab. 2023 Jul 5;140(3):107649. doi: 10.1016/j.ymgme.2023.107649. Epub ahead of print. PMID: 37517327.
  5. Lillås BS, Tøndel C, Melsom T, Eriksen BO, Marti HP, Vikse BE. Response to Birth Weight and Renal Functional Reserve in Adults. Kidney Int Rep. 2023 Jun 17;8(8):1700-1701. doi: 10.1016/j.ekir.2023.06.012. PMID: 37547517; PMCID: PMC10403668.
  6. Delaleu N, Marti HP, Strauss P, Sekulic M, Osman T, Tøndel C, Skrunes R, Leh S, Svarstad E, Nowak A, Gaspert A, Rusu E, Kwee I, Rinaldi A, Flatberg A, Eikrem O. Systems analyses of the Fabry kidney transcriptome and its response to enzyme replacement therapy identified and cross-validated enzyme replacement therapy-resistant targets amenable to drug repurposing. Kidney Int. 2023 Oct;104(4):803-819. doi: 10.1016/j.kint.2023.06.029. Epub 2023 Jul 5. PMID: 37419447.
  7. Lillås BS, Tøndel C, Melsom T, Eriksen BO, Marti HP, Vikse BE. Renal Functional Response-Association With Birth Weight and Kidney Volume. Kidney Int Rep. 2023 Feb 20;8(5):1034-1042. doi: 10.1016/j.ekir.2023.02.1079. PMID: 37180504; PMCID: PMC10166784.
  8. Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer SD, Haas F, Wong MN, Dumoulin B, Rischke P, Mühlig A, Sachs W, von Cossel K, Schulz K, Muschol N, Gersting SW, Muntau AC, Kretz O, Hahn O, Rinschen MM, Mauer M, Bork T, Grahammer F, Liang W, Eierhoff T, Römer W, Hansen A, Meyer-Schwesinger C, Iaccarino G, Tøndel C, Marti HP, Najafian B, Puelles VG, Schell C, Huber TB. Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy. J Clin Invest. 2023 Jun 1;133(11):e157782. doi: 10.1172/JCI157782. PMID: 37014703; PMCID: PMC10232004.
  9. Gjerstad AC, Skrunes R, Tøndel C, Åsberg A, Leh S, Klingenberg C, Døllner H, Hammarstrøm C, Bjerre AK. Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up. Pediatr Nephrol. 2023 Apr;38(4):1249-1256. doi: 10.1007/s00467-022-05706-y. Epub 2022 Aug 22. PMID: 35994104; PMCID: PMC9925570.
  10. Smeets NJL, Teunissen EMM, van der Velden K, van der Burgh MJP, Linders DE, Teesselink E, Moes DAR, Tøndel C, Ter Heine R, van Heijst A, Schreuder MF, de Wildt SN. Glomerular filtration rate in critically ill neonates and children: creatinine-based estimations versus iohexol-based measurements. Pediatr Nephrol. 2023 Apr;38(4):1087-1097. doi: 10.1007/s00467-022-05651-w. Epub 2022 Aug 2. PMID: 35916956; PMCID: PMC9925555.
  11. Grodås KTM, Døllner H, Thaulow CM, Knudsen PK, Tønnessen A, Skeibrok M, Klingenberg C. Gentamicin serum concentration measurement in children. Tidsskr Nor Laegeforen. 2023 Jan 16;143(1). English, Norwegian. doi: 10.4045/tidsskr.22.0238. PMID: 36655955.
  12. Elsaid HOA, Tjeldnes H, Rivedal M, Serre C, Eikrem Ø, Svarstad E, Tøndel C, Marti HP, Furriol J, Babickova J. Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca2+ Signaling Similar to Fabry Disease. Int J Mol Sci. 2022 Dec 26;24(1):358. doi: 10.3390/ijms24010358. PMID: 36613802; PMCID: PMC9820748.
  13. Tøndel C, Thurberg BL, DasMahapatra P, Lyn N, Maski M, Batista JL, George K, Patel H, Hariri A. Clinical relevance of globotriaosylceramide accumulation in Fabry disease and the effect of agalsidase beta in affected tissues. Mol Genet Metab. 2022 Dec;137(4):328-341. doi: 10.1016/j.ymgme.2022.10.005. Epub 2022 Oct 29. PMID: 36334424.
  14. Najafian B, Silvestroni A, Sokolovskiy A, Tøndel C, Svarstad E, Obrisca B, Ismail G, Holida MD, Mauer M. A novel unbiased method reveals progressive podocyte globotriaosylceramide accumulation and loss with age in females with Fabry disease. Kidney Int. 2022 Jul;102(1):173-182. doi: 10.1016/j.kint.2022.03.023. Epub 2022 Apr 26. PMID: 35483528; PMCID: PMC9233139.
  15. Elsaid HOA, Furriol J, Blomqvist M, Diswall M, Leh S, Gharbi N, Anonsen JH, Babickova J, Tøndel C, Svarstad E, Marti HP, Krause M. Reduced α-galactosidase A activity in zebrafish (Danio rerio) mirrors distinct features of Fabry nephropathy phenotype. Mol Genet Metab Rep. 2022 Feb 17;31:100851. doi: 10.1016/j.ymgmr.2022.100851. PMID: 35242583; PMCID: PMC8857658.
  16. Eide TT, Hufthammer KO, Brun A, Brackman D, Svarstad E, Tøndel C. Accuracy of single intravenous access iohexol GFR in children is hampered by marker contamination. Sci Rep. 2021 Dec 1;11(1):23224. doi: 10.1038/s41598-021-02759-1. PMID: 34853376; PMCID: PMC8636567.
  17. Lillås BS, Tøndel C, Aßmus J, Vikse BE. Low birthweight is associated with lower glomerular filtration rate in middle-aged mainly healthy women. Nephrol Dial Transplant. 2021 Dec 31;37(1):92-99. doi: 10.1093/ndt/gfaa306. PMID: 33313893; PMCID: PMC8719610.
  18. Tøndel C, Marti HP. Cardiovascular changes in young renal failure patients. Clin Kidney J. 2021 Nov 11;15(2):183-185. doi: 10.1093/ckj/sfab223. PMID: 35145633; PMCID: PMC8825223.z
  19. Thaulow CM, Lindemann PC, Klingenberg C. Antibiotic resistance in paediatric UTIs in Norway. Tidsskr Nor Laegeforen. 2021 Jun 8;141(10). English, Norwegian. doi: 10.4045/tidsskr.20.0889. PMID: 34182746.
  20. Najafian B, Tøndel C, Svarstad E, Gubler MC, Oliveira JP, Mauer M. Accumulation of Globotriaosylceramide in Podocytes in Fabry Nephropathy Is Associated with Progressive Podocyte Loss. J Am Soc Nephrol. 2020 Apr;31(4):865-875. doi: 10.1681/ASN.2019050497. Epub 2020 Mar 3. PMID: 32127409; PMCID: PMC7191924.
  21. Thorsteinsdottir H, Salvador CL, Mjøen G, Lie A, Sugulle M, Tøndel C, Brun A, Almaas R, Bjerre A. Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and after Renal Transplantation. Dis Markers. 2020 Feb 6;2020:6162892. doi: 10.1155/2020/6162892. PMID: 32089755; PMCID: PMC7026715.
  22. Lillås BS, Tøndel C, Gjerde A, Vikse BE. Measurement of renal functional response using iohexol clearance-a study of different outpatient procedures. Clin Kidney J. 2019 Nov 26;14(1):181-188. doi: 10.1093/ckj/sfz167. PMID: 33564417; PMCID: PMC7857819.
  23. Vollsæter M, Halvorsen T, Markestad T, Øymar K, Ueland PM, Meyer K, Midttun Ø, Bjørke-Monsen AL. Renal function and blood pressure in 11 year old children born extremely preterm or small for gestational age. PLoS One. 2018 Oct 12;13(10):e0205558. doi: 10.1371/journal.pone.0205558. PMID: 30312323; PMCID: PMC6185834.
  24. Salvador CL, Tøndel C, Rowe AD, Bjerre A, Brun A, Brackman D, Mørkrid L. Estimating glomerular filtration rate in children: evaluation of creatinine- and cystatin C-based equations. Pediatr Nephrol. 2019 Feb;34(2):301-311. doi: 10.1007/s00467-018-4067-3. Epub 2018 Aug 31. PMID: 30171354.
  25. Lerch C, Shroff R, Wan M, Rees L, Aitkenhead H, Kaplan Bulut I, Thurn D, Karabay Bayazit A, Niemirska A, Canpolat N, Duzova A, Azukaitis K, Yilmaz E, Yalcinkaya F, Harambat J, Kiyak A, Alpay H, Habbig S, Zaloszyc A, Soylemezoglu O, Candan C, Rosales A, Melk A, Querfeld U, Leifheit-Nestler M, Sander A, Schaefer F, Haffner D; 4C study consortium; ESPN CKD-MBD working group. Effects of nutritional vitamin D supplementation on markers of bone and mineral metabolism in children with chronic kidney disease. Nephrol Dial Transplant. 2018 Dec 1;33(12):2208-2217. doi: 10.1093/ndt/gfy012. PMID: 29481636.
  26. Tøndel C, Salvador CL, Hufthammer KO, Bolann B, Brackman D, Bjerre A, Svarstad E, Brun A. Iohexol plasma clearance in children: validation of multiple formulas and single-point sampling times. Pediatr Nephrol. 2018 Apr;33(4):683-696. doi: 10.1007/s00467-017-3841-y. Epub 2017 Nov 13. PMID: 29134449; PMCID: PMC5859061.
  27. Svarstad E, Leh S, Skrunes R, Kampevold Larsen K, Eikrem Ø, Tøndel C. Bedside Stereomicroscopy of Fabry Kidney Biopsies: An Easily Available Method for Diagnosis and Assessment of Sphingolipid Deposits. Nephron. 2018;138(1):13-21. doi: 10.1159/000479751. Epub 2017 Aug 26. PMID: 28848191.
  28. Salvador CL, Tøndel C, Rowe AD, Bjerre A, Brun A, Brackman D, Bolstad N, Mørkrid L. Renal Function Influences Diagnostic Markers in Serum and Urine: A Study of Guanidinoacetate, Creatine, Human Epididymis Protein 4, and Neutrophil Gelatinase-Associated Lipocalin in Children. J Appl Lab Med. 2017 Nov 1;2(3):297-308. doi: 10.1373/jalm.2016.022145. PMID: 33636843.
  29. Skrunes R, Tøndel C, Leh S, Larsen KK, Houge G, Davidsen ES, Hollak C, van Kuilenburg ABP, Vaz FM, Svarstad E. Long-Term Dose-Dependent Agalsidase Effects on Kidney Histology in Fabry Disease. Clin J Am Soc Nephrol. 2017 Sep 7;12(9):1470-1479. doi: 10.2215/CJN.01820217. Epub 2017 Jun 16. PMID: 28625968; PMCID: PMC5586567.
  30. Eikrem Ø, Skrunes R, Tøndel C, Leh S, Houge G, Svarstad E, Marti HP. Pathomechanisms of renal Fabry disease. Cell Tissue Res. 2017 Jul;369(1):53-62. doi: 10.1007/s00441-017-2609-9. Epub 2017 Apr 12. PMID: 28401309.
  31. Schiffmann R, Hughes DA, Linthorst GE, Ortiz A, Svarstad E, Warnock DG, West ML, Wanner C; Conference Participants. Screening, diagnosis, and management of patients with Fabry disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference. Kidney Int. 2017 Feb;91(2):284-293. doi: 10.1016/j.kint.2016.10.004. Epub 2016 Dec 18. PMID: 27998644.
  32. Tøndel C, Bolann B, Salvador CL, Brackman D, Bjerre A, Svarstad E, Brun A. Iohexol plasma clearance in children: validation of multiple formulas and two-point sampling times. Pediatr Nephrol. 2017 Feb;32(2):311-320. doi: 10.1007/s00467-016-3436-z. Epub 2016 Jul 1. Erratum in: Pediatr Nephrol. 2017 Feb;32(2):375-376. PMID: 27369694; PMCID: PMC5203838.
  33. Skrunes R, Svarstad E, Kampevold Larsen K, Leh S, Tøndel C. Reaccumulation of globotriaosylceramide in podocytes after agalsidase dose reduction in young Fabry patients. Nephrol Dial Transplant. 2017 May 1;32(5):807-813. doi: 10.1093/ndt/gfw094. PMID: 27190352.
  34. Najafian B, Tøndel C, Svarstad E, Sokolovkiy A, Smith K, Mauer M. One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease. PLoS One. 2016 Apr 15;11(4):e0152812. doi: 10.1371/journal.pone.0152812. PMID: 27081853; PMCID: PMC4833322.
  35. Salvador CL, Tøndel C, Mørkrid L, Bjerre A, Brun A, Bolann B, Brackman D, Bergan S. Glomerular filtration rate measured by iohexol clearance: A comparison of venous samples and capillary blood spots. Scand J Clin Lab Invest. 2015;75(8):710-6. doi: 10.3109/00365513.2015.1091091. PMID: 26426851.
  36. Tøndel C, Kanai T, Larsen KK, Ito S, Politei JM, Warnock DG, Svarstad E. Foot process effacement is an early marker of nephropathy in young classic Fabry patients without albuminuria. Nephron. 2015;129(1):16-21. doi: 10.1159/000369309. Epub 2014 Dec 17. PMID: 25531941.
  37. Mauer M, Glynn E, Svarstad E, Tøndel C, Gubler MC, West M, Sokolovskiy A, Whitley C, Najafian B. Mosaicism of podocyte involvement is related to podocyte injury in females with Fabry disease. PLoS One. 2014 Nov 11;9(11):e112188. doi: 10.1371/journal.pone.0112188. PMID: 25386848; PMCID: PMC4227696.
  38. van der Tol L, Svarstad E, Ortiz A, Tøndel C, Oliveira JP, Vogt L, Waldek S, Hughes DA, Lachmann RH, Terryn W, Hollak CE, Florquin S, van den Bergh Weerman MA, Wanner C, West ML, Biegstraaten M, Linthorst GE. Chronic kidney disease and an uncertain diagnosis of Fabry disease: approach to a correct diagnosis. Mol Genet Metab. 2015 Feb;114(2):242-7. doi: 10.1016/j.ymgme.2014.08.007. Epub 2014 Aug 20. PMID: 25187469.
  39. Tøndel C, Bostad L, Larsen KK, Hirth A, Vikse BE, Houge G, Svarstad E. Agalsidase benefits renal histology in young patients with Fabry disease. J Am Soc Nephrol. 2013 Jan;24(1):137-48. doi: 10.1681/ASN.2012030316. PMID: 23274955; PMCID: PMC3537211.
  40. Tøndel C, Vikse BE, Bostad L, Svarstad E. Safety and complications of percutaneous kidney biopsies in 715 children and 8573 adults in Norway 1988-2010. Clin J Am Soc Nephrol. 2012 Oct;7(10):1591-7. doi: 10.2215/CJN.02150212. Epub 2012 Jul 26. PMID: 22837269; PMCID: PMC3463204.
  41. Najafian B, Svarstad E, Bostad L, Gubler MC, Tøndel C, Whitley C, Mauer M. Progressive podocyte injury and globotriaosylceramide (GL-3) accumulation in young patients with Fabry disease. Kidney Int. 2011 Mar;79(6):663-670. doi: 10.1038/ki.2010.484. Epub 2010 Dec 15. PMID: 21160462; PMCID: PMC3640823.
  42. Tøndel C, Ramaswami U, Aakre KM, Wijburg F, Bouwman M, Svarstad E. Monitoring renal function in children with Fabry disease: comparisons of measured and creatinine-based estimated glomerular filtration rate. Nephrol Dial Transplant. 2010 May;25(5):1507-13. doi: 10.1093/ndt/gfp658. Epub 2009 Dec 27. PMID: 20038520.
  43. Cybulla M, Walter KN, Schwarting A, Divito R, Feriozzi S, Sunder-Plassmann G; European FOS Investigators Group. Kidney transplantation in patients with Fabry disease. Transpl Int. 2009 Apr;22(4):475-81. doi: 10.1111/j.1432-2277.2008.00824.x. Epub 2009 Jan 22. PMID: 19207191.
  44. Aakre KM, Tøndel C, Brun A, Svarstad E. The MDRD equation may mask decline of glomerular filtration rate in Fabry patients with normal or nearly normal kidney function. Clin Nephrol. 2009 Feb;71(2):118-24. doi: 10.5414/cnp71118. PMID: 19203503.
  45. Tøndel C, Bostad L, Hirth A, Svarstad E. Renal biopsy findings in children and adolescents with Fabry disease and minimal albuminuria. Am J Kidney Dis. 2008 May;51(5):767-76. doi: 10.1053/j.ajkd.2007.12.032. Epub 2008 Mar 20. Erratum in: Am J Kidney Dis. 2009 Mar;53(3):567. PMID: 18436087.
  46. Tøndel C, Bostad L, Laegreid LM, Houge G, Svarstad E. Prominence of glomerular and vascular changes in renal biopsies in children and adolescents with Fabry disease and microalbuminuria. Clin Ther. 2008;30 Suppl B:S42. doi: 10.1016/s0149-2918(08)80036-7. PMID: 18395135.
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  48. Misselwitz J, Hesse V, Markestad T. Nephrocalcinosis, hypercalciuria and elevated serum levels of 1,25-dihydroxyvitamin D in children. Possible link to vitamin D toxicity. Acta Paediatr Scand. 1990 Jun-Jul;79(6-7):637-43. doi: 10.1111/j.1651-2227.1990.tb11528.x. PMID: 2386055.
Malignancies in childhood

200 children get cancer every year in Norway. Continuous systematic clinical research is performed to increase survival, reduce side effects and personalize the treatment.

 

PhD dissertations:

Peer review publications:

  1. Bratteteig M, Rueegg CS, Lie HC, Thorsen L, Larsen EH, Larsen MH, Torsvik IK, Götte M, Järvelä LS, Kriemler S, Larsen HB, Anderssen SA, Ruud E, Grydeland M. Physical activity behaviors and screen time in young childhood cancer survivors: the Physical Activity in Childhood Cancer Survivors Study. J Cancer Surviv. 2024 Sep 17. doi: 10.1007/s11764-024-01671-7. Epub ahead of print. PMID: 39287916.
  2. Yndestad S, Haugland HK, Goplen D, Wojcik D, Knappskog S, Lønning PE. Germline variants in patients diagnosed with pediatric soft tissue sarcoma. Acta Oncol. 2024 Jul 22;63:586-591. doi: 10.2340/1651-226X.2024.40730. PMID: 39037077; PMCID: PMC11332449.
  3. Gunnes MW, Benneche A, Bechensteen AG. Et barn med langvarig anemi [A child with persistent anaemia]. Tidsskr Nor Laegeforen. 2024 Mar 15;144(4). Norwegian. doi: 10.4045/tidsskr.23.0415. PMID: 38506013.
  4. Heymer EJ, Hawkins MM, Winter DL, Teepen JC, Sunguc C, Ronckers CM, Allodji RS, Alessi D, Sugden E, Belle FN, Bagnasco F, Byrne J, Bárdi E, Garwicz S, Grabow D, Jankovic M, Kaatsch P, Kaiser M, Michel G, Schindera C, Haddy N, Journy N, Česen Mazić M, Skinner R, Kok JL, Gunnes MW, Wiebe T, Sacerdote C, Maule MM, Terenziani M, Jakab Z, Winther JF, Lähteenmäki PM, Zadravec Zaletel L, Haupt R, Kuehni CE, Kremer LC, de Vathaire F, Hjorth L, Reulen RC. Risk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study. Br J Cancer. 2024 Apr;130(6):976-986. doi: 10.1038/s41416-024-02577-y. Epub 2024 Jan 19. PMID: 38243010; PMCID: PMC10951281.
  5. Gunnes MW, Benneche A, Bechensteen AG. Et barn med langvarig anemi. Tidsskr Nor Laegeforen. 2024 Mar 15;144(4). Norwegian. doi: 10.4045/tidsskr.23.0415. PMID: 38506013.
  6. Heymer EJ, Jóźwiak K, Kremer LC, Winter DL, de Vathaire F, Sunguc C, Sugden E, Kok JL, van der Pal HJH, Hjorth L, Jakab Z, Maule MM, Haupt R, Bagnasco F, Terenziani M, Diallo I, Gunnes MW, Sommer G, Zadravec Zaletel L, Kuehni CE, Winther JF, Lähteenmäki PM, Gudmundsdottir T, Allodji RS, Skinner R, Ronckers CM, Hawkins MM, Reulen RC, Teepen JC. Cumulative Absolute Risk of Subsequent Colorectal Cancer After Abdominopelvic Radiotherapy Among Childhood Cancer Survivors: A PanCareSurFup Study. J Clin Oncol. 2024 Jan 20;42(3):336-347. doi: 10.1200/JCO.23.00452. Epub 2023 Nov 16. PMID: 37972325.
  7. Peyrl A, Chocholous M, Sabel M, Lassaletta A, Sterba J, Leblond P, Nysom K, Torsvik I, Chi SN, Perwein T, Jones N, Holm S, Nyman P, Mörse H, Öberg A, Weiler-Wichtl L, Leiss U, Haberler C, Schmook MT, Mayr L, Dieckmann K, Kool M, Gojo J, Azizi AA, André N, Kieran M, Slavc I. Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial. JAMA Oncol. 2023 Oct 26:e234437. doi: 10.1001/jamaoncol.2023.4437. Epub ahead of print. PMID: 37883081; PMCID: PMC10603581.
  8. Bratteteig M, Rueegg CS, Raastad T, Grydeland M, Torsvik IK, Schindera C, Ruud E, Anderssen SA. Physical Activity, Fitness, and Cardiovascular Disease Risk in Adolescent Childhood Cancer Survivors Compared to Controls: The Physical Activity in Childhood Cancer Survivors Study. J Adolesc Young Adult Oncol. 2023 Sep 13. doi: 10.1089/jayao.2023.0063. Epub ahead of print. PMID: 37703544.
  9. Grydeland M, Bratteteig M, Rueegg CS, Lie HC, Thorsen L, Larsen EH, Brügmann-Pieper S, Torsvik IK, Götte M, Lähteenmäki PM, Kriemler S, Fridh MK, Anderssen SA, Ruud E. Physical Activity Among Adolescent Cancer Survivors: The PACCS Study. Pediatrics. 2023 Sep 1;152(3):e2023061778. doi: 10.1542/peds.2023-061778. PMID: 37646086.
  10. Andries A, Ørstavik K, Rueegg CS, Eng S, Edvardsen E, Allen SM, Torsvik IK, Raastad T, Ruud E, Nilsen KB. Polyneuropathy in Adolescent Childhood Cancer Survivors: The PACCS Study. Pediatr Neurol. 2023 Mar;140:9-17. doi: 10.1016/j.pediatrneurol.2022.11.012. Epub 2022 Nov 25. PMID: 36586183.
  11. Dudley IM, Sunguc C, Heymer EJ, Winter DL, Teepen JC, Belle FN, Bárdi E, Bagnasco F, Gudmundsdottir T, Skinner R, Michel G, Byrne J, Øfstaas H, Jankovic M, Mazić MČ, Mader L, Loonen J, Garwicz S, Wiebe T, Alessi D, Allodji RS, Haddy N, Grabow D, Kaatsch P, Kaiser M, Maule MM, Jakab Z, Gunnes MW, Terenziani M, Zaletel LZ, Kuehni CE, Haupt R, de Vathaire F, Kremer LC, Lähteenmäki PM, Winther JF, Hjorth L, Hawkins MM, Reulen RC. Risk of subsequent primary lymphoma in a cohort of 69,460 five-year survivors of childhood and adolescent cancer in Europe: The PanCareSurFup study. Cancer. 2023 Feb 1;129(3):426-440. doi: 10.1002/cncr.34561. Epub 2022 Nov 29. PMID: 36444554; PMCID: PMC10099796.
  12. Sunguc C, Hawkins MM, Winter DL, Dudley IM, Heymer EJ, Teepen JC, Allodji RS, Belle FN, Bagnasco F, Byrne J, Bárdi E, Ronckers CM, Haddy N, Gudmundsdottir T, Garwicz S, Jankovic M, van der Pal HJH, Mazić MČ, Schindera C, Grabow D, Maule MM, Kaatsch P, Kaiser M, Fresneau B, Michel G, Skinner R, Wiebe T, Sacerdote C, Jakab Z, Gunnes MW, Terenziani M, Winther JF, Lähteenmäki PM, Zaletel LZ, Kuehni CE, Kremer LC, Haupt R, de Vathaire F, Hjorth L, Reulen RC. Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study. Br J Cancer. 2023 Jan;128(1):80-90. doi: 10.1038/s41416-022-02016-w. Epub 2022 Nov 1. PMID: 36319851; PMCID: PMC9814398.
  13. Bratteteig M, Anderssen SA, Rueegg CS, Ruud E, Torsvik IK, Kriemler S, Grydeland M. Device-measured physical activity and cardiovascular disease risk in adolescent childhood cancer survivors. A physical activity in childhood cancer survivors (PACCS) study. Front Pediatr. 2022 Aug 25;10:977365. doi: 10.3389/fped.2022.977365. PMID: 36090557; PMCID: PMC9453306.
  14. Hermansen JU, Wojcik DM, Robinson N, Pahnke J, Haugland HK, Jamtøy AH, Flaegstad T, Halvorsen H, Lund B, Baumbusch LO, Munthe-Kaas MC. The Norwegian childhood cancer biobank. Cancer Rep (Hoboken). 2022 Aug;5(8):e1555. doi: 10.1002/cnr2.1555. Epub 2021 Sep 20. PMID: 34541832; PMCID: PMC9351664.
  15. Grønbæk JK, Laustsen AF, Toescu S, Pizer B, Mallucci C, Aquilina K, Molinari E, Hjort MA, Gumbeleviciene L, Hauser P, Pálmafy B, van Baarsen K, Hoving E, Zipfel J, Ehrstedt C, Grillner P, Callesen MT, Frič R, Wibroe M, Nysom K, Schmiegelow K, Sehested A, Mathiasen R, Juhler M; CMS study group. Left-handedness should not be overrated as a risk factor for postoperative speech impairment in children after posterior fossa tumour surgery: a prospective European multicentre study. Childs Nerv Syst. 2022 Aug;38(8):1479-1485. doi: 10.1007/s00381-022-05567-8. Epub 2022 Jun 27. PMID: 35759029.
  16. Lie HC, Anderssen S, Rueegg CS, Raastad T, Grydeland M, Thorsen L, Stensrud T, Edvardsen E, Larsen MH, Torsvik IK, Bovim LP, Götte M, Lähteenmäki PM, Kriemler S, Larsen HB, Fridh MK, Ørstavik K, Brun H, Matthews I, Hornset E, Ruud E. The Physical Activity and Fitness in Childhood Cancer Survivors (PACCS) Study: Protocol for an International Mixed Methods Study. JMIR Res Protoc. 2022 Mar 8;11(3):e35838. doi: 10.2196/35838. PMID: 35258456; PMCID: PMC8941432.
  17. Grønbæk JK, Wibroe M, Toescu S, Frič R, Thomsen BL, Møller LN, Grillner P, Gustavsson B, Mallucci C, Aquilina K, Fellows GA, Molinari E, Hjort MA, Westerholm-Ormio M, Kiudeliene R, Mudra K, Hauser P, van Baarsen K, Hoving E, Zipfel J, Nysom K, Schmiegelow K, Sehested A, Juhler M, Mathiasen R; CMS study group. Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study. Lancet Child Adolesc Health. 2021 Nov;5(11):814-824. doi: 10.1016/S2352-4642(21)00274-1. Epub 2021 Oct 6. PMID: 34624241.
  18. Thastrup M, Marquart HV, Levinsen M, Modvig S, Abrahamsson J, Albertsen BK, Frost BM, Harila-Saari A, Pesola J, Ulvmoen A, Wojcik DM, Taskinen M, Hoffmann M, Lausen B, Schmiegelow K; Nordic Society of Paediatric Haematology, Oncology (NOPHO). Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia. Br J Haematol. 2021 Oct;195(1):119-122. doi: 10.1111/bjh.17769. Epub 2021 Aug 15. PMID: 34396501.
  19. Brenner AK, Gunnes MW. Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma-A Comprehensive Update. Pharmaceutics. 2021 Sep 8;13(9):1427. doi: 10.3390/pharmaceutics13091427. PMID: 34575503; PMCID: PMC8470592.
  20. Stensvold E, Myklebust TÅ, Cappelen J, Due-Tønnessen BJ, Due-Tønnessen P, Kepka A, Johannesen TB, Krossnes B, Lundar T, Maric S, Miletic H, Moholdt V, Myrmel KS, Nordberg T, Rydland J, Stokland T, Solem K, Solheim O, Torsvik I, Wikran GC, Zeller B, Wesenberg F, Bechensteen AG, Brandal P. Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival. Pediatr Blood Cancer. 2019 Oct;66(10):e27910. doi: 10.1002/pbc.27910. Epub 2019 Jul 1. PMID: 31264356.
  21. El-Khouly FE, Veldhuijzen van Zanten SEM, Santa-Maria Lopez V, Hendrikse NH, Kaspers GJL, Loizos G, Sumerauer D, Nysom K, Pruunsild K, Pentikainen V, Thorarinsdottir HK, Rutkauskiene G, Calvagna V, Drogosiewicz M, Dragomir M, Deak L, Kitanovski L, von Bueren AO, Kebudi R, Slavc I, Jacobs S, Jadrijevic-Cvrlje F, Entz-Werle N, Grill J, Kattamis A, Hauser P, Pears J, Biassoni V, Massimino M, Lopez Aguilar E, Torsvik IK, Joao Gil-da-Costa M, Kumirova E, Cruz-Martinez O, Holm S, Bailey S, Hayden T, Thomale UW, Janssens GOR, Kramm CM, van Vuurden DG. Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand? J Neurooncol. 2019 Oct;145(1):177-184. doi: 10.1007/s11060-019-03287-9. Epub 2019 Sep 14. PMID: 31522324; PMCID: PMC6775536.
  22. Kvistad SAS, Gunnes MW, Hagen KG, Berentsen S. A three year-old boy with back pain, fever and cola-coloured urine. Tidsskr Nor Laegeforen. 2019 Mar 18;139(6). English, Norwegian. doi: 10.4045/tidsskr.18.0532. PMID: 30917633.
  23. Veldhuijzen van Zanten SEM, Baugh J, Chaney B, De Jongh D, Sanchez Aliaga E, Barkhof F, Noltes J, De Wolf R, Van Dijk J, Cannarozzo A, Damen-Korbijn CM, Lieverst JA, Colditz N, Hoffmann M, Warmuth-Metz M, Bison B, Jones DTW, Sturm D, Gielen GH, Jones C, Hulleman E, Calmon R, Castel D, Varlet P, Giraud G, Slavc I, Van Gool S, Jacobs S, Jadrijevic-Cvrlje F, Sumerauer D, Nysom K, Pentikainen V, Kivivuori SM, Leblond P, Entz-Werle N, von Bueren AO, Kattamis A, Hargrave DR, Hauser P, Garami M, Thorarinsdottir HK, Pears J, Gandola L, Rutkauskiene G, Janssens GO, Torsvik IK, Perek-Polnik M, Gil-da-Costa MJ, Zheludkova O, Shats L, Deak L, Kitanovski L, Cruz O, Morales La Madrid A, Holm S, Gerber N, Kebudi R, Grundy R, Lopez-Aguilar E, Zapata-Tarres M, Emmerik J, Hayden T, Bailey S, Biassoni V, Massimino M, Grill J, Vandertop WP, Kaspers GJL, Fouladi M, Kramm CM, van Vuurden DG; members of the SIOPE DIPG Network. Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease. J Neurooncol. 2017 Apr;132(2):255-266. doi: 10.1007/s11060-016-2363-y. Epub 2017 Jan 21. PMID: 28110411; PMCID: PMC5378734.
  24. Gunnes MW, Lie RT, Bjørge T, Ghaderi S, Syse A, Ruud E, Wesenberg F, Moster D. Suicide and violent deaths in survivors of cancer in childhood, adolescence and young adulthood-A national cohort study. Int J Cancer. 2017 Feb 1;140(3):575-580. doi: 10.1002/ijc.30474. Epub 2016 Oct 26. PMID: 27750385.
  25. Gunnes MW, Lie RT, Bjørge T, Syse A, Ruud E, Wesenberg F, Moster D. Economic independence in survivors of cancer diagnosed at a young age: A Norwegian national cohort study. Cancer. 2016 Dec 15;122(24):3873-3882. doi: 10.1002/cncr.30253. Epub 2016 Aug 12. PMID: 27518040; PMCID: PMC5157778.
  26. Veldhuijzen van Zanten SE, van Meerwijk CL, Jansen MH, Twisk JW, Anderson AK, Coombes L, Breen M, Hargrave OJ, Hemsley J, Craig F, Cruz O, Kaspers GJ, van Vuurden DG, Hargrave DR; SIOPE DIPG Network. Palliative and end-of-life care for children with diffuse intrinsic pontine glioma: results from a London cohort study and international survey. Neuro Oncol. 2016 Apr;18(4):582-8. doi: 10.1093/neuonc/nov250. Epub 2015 Oct 11. PMID: 26459800; PMCID: PMC4799684.
  27. Mjelle AB, Donner EM, Berg A. Et barn med kramper og plutselig synstap under cellegiftbehandling [A child with cramps and sudden vision loss during chemotherapy]. Tidsskr Nor Laegeforen. 2015 Mar 10;135(5):441-4. Norwegian. doi: 10.4045/tidsskr.13.1486. PMID: 25761031.
  28. Tuckuviene R, Ranta S, Albertsen BK, Andersson NG, Bendtsen MD, Frisk T, Gunnes MW, Helgestad J, Heyman MM, Jonsson OG, Mäkipernaa A, Pruunsild K, Tedgård U, Trakymiene SS, Ruud E. Prospective study of thromboembolism in 1038 children with acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology (NOPHO) study. J Thromb Haemost. 2016 Mar;14(3):485-94. doi: 10.1111/jth.13236. Epub 2016 Jan 30. PMID: 26707629.
  29. Ghaderi S, Engeland A, Gunnes MW, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Educational attainment among long-term survivors of cancer in childhood and adolescence: a Norwegian population-based cohort study. J Cancer Surviv. 2016 Feb;10(1):87-95. doi: 10.1007/s11764-015-0453-z. Epub 2015 May 1. PMID: 25929213.
  30. Ghaderi S, Engeland A, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Increased uptake of social security benefits among long-term survivors of cancer in childhood, adolescence and young adulthood: a Norwegian population-based cohort study. Br J Cancer. 2013 Apr 16;108(7):1525-33. doi: 10.1038/bjc.2013.107. Epub 2013 Mar 12. PMID: 23481179; PMCID: PMC3629421.
  31. Ghaderi S, Lie RT, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Cancer in childhood, adolescence, and young adults: a population-based study of changes in risk of cancer death during four decades in Norway. Cancer Causes Control. 2012 Aug;23(8):1297-305. doi: 10.1007/s10552-012-0007-x. Epub 2012 Jun 17. Erratum in: Cancer Causes Control. 2013 Dec;24(12):2253-6. PMID: 22706693.
  32. Hirth A, Pedersen PH, Wester K, Mörk S, Helgestad J. Cerebral atypical teratoid/rhabdoid tumor of infancy: long-term survival after multimodal treatment, also including triple intrathecal chemotherapy and gamma knife radiosurgery--case report. Pediatr Hematol Oncol. 2003 Jun;20(4):327-32. PMID: 12746165.
  33. Hirth A, Pedersen PH, Baardsen R, Larsen JL, Krossnes BK, Helgestad J. Gamma-knife radiosurgery in pediatric cerebral and skull base tumors. Med Pediatr Oncol. 2003 Feb;40(2):99-103. doi: 10.1002/mpo.10218. PMID: 12461793.
Cardiac disease and resuscitation in childhood
  • Exercise testing in cardiac disease
  • Clinical research on resuscitation
  • Echocardiographic studies before and after birth and in chronic diseases
  • Register studies on heart diseases and resuscitation
  • Extra-cardiac health challenges in patients with congenital heart disease
  • Vascular endothelial function in children and young adults

PhD dissertations:

 

Media:

https://www.nrk.no/vestland/vil-finne-ut-om-hjertesyke-barn-kan-trene-bedre-i-vann-enn-pa-land-1.14837429

https://www.bt.no/nyheter/lokalt/i/wlxeM/her-skal-odd-erik-faa-testet-hjertet-sitt

https://www.tannlegetidende.no/journal/2012/8/dntt-486748/Anbefalinger_for_bruk_av_endokardittprofylakse_knyttet_til_tannbehandling

 

Peer review publications:

  1. Sandberg M, Fomina T, Macsali F, Greve G, Øyen N, Leirgul E. Labor onset and delivery mode in women with congenital heart disease-A nationwide cohort study. Acta Obstet Gynecol Scand. 2025 Apr;104(4):666-675. doi: 10.1111/aogs.15064. Epub 2025 Jan 29. PMID: 39878100; PMCID: PMC11919723.
  2. Bekkevold M, Solvik-Olsen T, Heyerdahl F, Lang AM, Hagemo J, Rehn M; NeoTemplate Collaborating Group. Reporting interhospital neonatal intensive care transport: international five-step Delphi-based template. BMJ Paediatr Open. 2024 Apr 2;8(1):e002374. doi: 10.1136/bmjpo-2023-002374. PMID: 38569741; PMCID: PMC10989109.
  3. Sandberg M, Fomina T, Macsali F, Greve G, Estensen ME, Øyen N, Leirgul E. Time trends and birth rates in women with congenital heart disease; a nationwide cohort study from Norway 1994-2014. Int J Cardiol Congenit Heart Dis. 2024 Mar 30;16:100507. doi: 10.1016/j.ijcchd.2024.100507. PMID: 39712532; PMCID: PMC11657671.
  4. Mørch J, Kolnes EH, Greve G, Omdal TR, Ebbing C, Kessler J, Khan U. Increasing region of interest width reduces neonatal circumferential strain. Echocardiography. 2024 Jul;41(7):e15873. doi: 10.1111/echo.15873. PMID: 38985125.
  5. Sandberg M, Fomina T, Macsali F, Greve G, Øyen N, Leirgul E. Preeclampsia and neonatal outcomes in pregnancies with maternal congenital heart disease: A nationwide cohort study from Norway. Acta Obstet Gynecol Scand. 2024 Sep;103(9):1847-1858. doi: 10.1111/aogs.14902. Epub 2024 Jul 1. PMID: 38946266; PMCID: PMC11324925.
  6. Tveiten L, Diep LM, Halvorsen T, Markestad T. Normal range and risk factors for deviating body temperatures during the first 24 hours in term-born infants under standardised care: an observational study. BMJ Paediatr Open. 2024 May 31;8(1):e002596. doi: 10.1136/bmjpo-2024-002596. PMID: 38823799; PMCID: PMC11149163.
  7. Høyvik HE, Straume V, Østerås Ø, Engan M. Triaging of acutely ill children transported by ambulance. Tidsskr Nor Laegeforen. 2024 Jan 10;144(1). English, Norwegian. doi: 10.4045/tidsskr.23.0480. PMID: 38258724.
  8. Tveiten L, Diep LM, Halvorsen T, Markestad T. Normal range and risk factors for deviating body temperatures during the first 24 hours in term-born infants under standardised care: an observational study. BMJ Paediatr Open. 2024 May 31;8(1):e002596. doi: 10.1136/bmjpo-2024-002596. PMID: 38823799; PMCID: PMC11149163
  9. Engan B, Diab S, Brun H, Raastad T, Torsvik IK, Omdal TR, Ghavidel FZ, Greve G, Ruud E, Edvardsen E, Leirgul E. Systolic myocardial function measured by echocardiographic speckle-tracking and peak oxygen consumption in pediatric childhood cancer survivors-a PACCS study. Front Cardiovasc Med. 2023 Jul 5;10:1221787. doi: 10.3389/fcvm.2023.1221787. PMID: 37476575; PMCID: PMC10354364.
  10. Vederhus BJ, Olsen MS, Eide GE, Storm H, Guthe HJ. ALPS-Neo pain and stress assessment scale for neonates-A measure for procedural pain. Acta Paediatr. 2023 Jun;112(6):1220-1225. doi: 10.1111/apa.16759. Epub 2023 Mar 28. PMID: 36938888.
  11. Engan B, Omdal TR, Greve G, Vollsaeter M, Leirgul E. Myocardial function including estimates of myocardial work in young adults born very preterm or with extremely low birthweight - a cohort study. BMC Cardiovasc Disord. 2023 Apr 29;23(1):222. doi: 10.1186/s12872-023-03253-4. PMID: 37120542; PMCID: PMC10149027.
  12. Forster RB, Kjellstadli C, Myklebust TÅ, Egeland G, Sulo G, Bjørge T, Bønaa KH, Juliusson PB, Kvåle R. Treatment and 30-Day Mortality after Myocardial Infarction in Prostate Cancer Patients: A Population-Based Study from Norway. Cardiology. 2023;148(1):83-92. doi: 10.1159/000527636. Epub 2022 Oct 19. PMID: 36260991.
  13. Markussen DL, Brevik HS, Bjørneklett RO, Engan M. Validation of a modified South African triage scale in a high-resource setting: a retrospective cohort study. Scand J Trauma Resusc Emerg Med. 2023 Mar 20;31(1):13. doi: 10.1186/s13049-023-01076-y. PMID: 36941710; PMCID: PMC10026449.
  14. Eriksson P, Pihkala J, Jensen AS, Dohlen G, Liuba P, Wahlander H, Sjoberg G, Hlebowicz J, Furenas E, Leirgul E, Settergren M, Vithessonthi K, Nielsen NE, Christersson C, Sondergaard L, Sinisalo J, Nielsen-Kudsk JE, Dellborg M, Larsen SH. Transcatheter Intervention for Coarctation of the Aorta: A Nordic Population-Based Registry With Long-Term Follow-Up. JACC Cardiovasc Interv. 2023 Feb 27;16(4):444-453. doi: 10.1016/j.jcin.2022.11.007. PMID: 36858664.
  15. Dahle-Andersen AC, Amini N, Engan M, Brodwall K. Introduction of a high dependency unit at a large paediatric and adolescent medicine department. Tidsskr Nor Laegeforen. 2022 Dec 12;142(18). English, Norwegian. doi: 10.4045/tidsskr.22.0001. PMID: 36511750.
  16. Sinha MD, Azukaitis K, Sladowska-Kozłowska J, Bårdsen T, Merkevicius K, Karlsen Sletten IS, Obrycki Ł, Pac M, Fernández-Aranda F, Bjelakovic B, Jankauskiene A, Litwin M; HyperChildNet Working Group. Prevalence of left ventricular hypertrophy in children and young people with primary hypertension: Meta-analysis and meta-regression. Front Cardiovasc Med. 2022 Oct 31;9:993513. doi: 10.3389/fcvm.2022.993513. PMID: 36386367; PMCID: PMC9659762.
  17. Markestad T. Decisions at the limit of viability. Acta Paediatr. 2022 Aug;111(8):1472-1473. doi: 10.1111/apa.16378. Epub 2022 May 8. PMID: 35527403.
  18. Jensen AS, Jørgensen TH, Christersson C, Nagy E, Sinisalo J, Furenäs E, Gjesdal O, Eriksson P, Vejlstrup N, Johansson B, Hlebowicz J, Greve G, Dellborg M, Skulstad H, Kvidal P, Jokinen E, Sairanen H, Thilén U, Søndergaard L. Cause-Specific Mortality in Patients During Long-Term Follow-Up After Atrial Switch for Transposition of the Great Arteries. J Am Heart Assoc. 2022 Jul 19;11(14):e023921. doi: 10.1161/JAHA.121.023921. Epub 2022 Jul 5. PMID: 35861834; PMCID: PMC9707826.
  19. Reigstad H, Hufthammer KO, Rønnestad AE, Klingenberg C, Stensvold HJ, Markestad T; Norwegian Neonatal Network. Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study. BMJ Paediatr Open. 2022 Jul;6(1):e001527. doi: 10.1136/bmjpo-2022-001527. PMID: 36053649; PMCID: PMC9335034.
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  96. Meberg A, Andreassen A, Brunvand L, Markestad T, Moster D, Nietsch L, Silberg IE, Skålevik JE. Pulse oximetry screening as a complementary strategy to detect critical congenital heart defects. Acta Paediatr. 2009 Apr;98(4):682-6. doi: 10.1111/j.1651-2227.2008.01199.x. Epub 2008 Jan 15. PMID: 19154526.
  97. Edwards NC, Hirth A, Ferro CJ, Townend JN, Steeds RP. Subclinical abnormalities of left ventricular myocardial deformation in early-stage chronic kidney disease: the precursor of uremic cardiomyopathy? J Am Soc Echocardiogr. 2008 Dec;21(12):1293-8. doi: 10.1016/j.echo.2008.09.013. PMID: 19041571.
  98. Meberg A, Brügmann-Pieper S, Due R Jr, Eskedal L, Fagerli I, Farstad T, Frøisland DH, Sannes CH, Johansen OJ, Keljalic J, Markestad T, Nygaard EA, Røsvik A, Silberg IE. First day of life pulse oximetry screening to detect congenital heart defects. J Pediatr. 2008 Jun;152(6):761-5. doi: 10.1016/j.jpeds.2007.12.043. Epub 2008 Mar 6. Erratum in: J Pediatr. 2009 Apr;154(4):629. PMID: 18492511.
  99. Hirth A, Nightingale S, Wilmshurst P, Disney P, Thorne S. Prevalence of migraine in adults with cyanotic congenital heart disease. Congenit Heart Dis. 2008 Mar-Apr;3(2):124-7. doi: 10.1111/j.1747-0803.2008.00167.x. PMID: 18380761.
  100. Svangtun H, Greve G, Leirgul E, Berg A. Intrauterin veksthemming og vaskulaere forandringer hos nyfødte [Intrauterine growth retardation and vascular changes in neonates]. Tidsskr Nor Laegeforen. 2008 Jan 17;128(2):177-9. Norwegian. PMID: 18240392.
  101. Aburawi EH, Berg A, Liuba P, Pesonen E. Effects of cardiopulmonary bypass surgery on coronary flow in children assessed with transthoracic Doppler echocardiography. Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1138-43. doi: 10.1152/ajpheart.00025.2007. Epub 2007 May 4. PMID: 17483244.
  102. Hirth A, Berg A, Greve G. Successful treatment of severe heart failure in an infant with Hurler syndrome. J Inherit Metab Dis. 2007 Oct;30(5):820. doi: 10.1007/s10545-007-0613-z. Epub 2007 Sep 4. PMID: 17768668.
  103. Aburawi EH, Liuba P, Berg A, Pesonen E. A transthoracic Doppler echocardiography study of C-reactive protein and coronary microcirculation in children after open heart surgery. Cardiol Young. 2007 Oct;17(5):472-7. doi: 10.1017/S1047951107000972. Epub 2007 Jul 18. PMID: 17634161.
  104. Trønnes H, Norgård G, Berg A. En gutt på ni uker med høy feber og diaré [A 9-week-old boy with fever and diarrhoea]. Tidsskr Nor Laegeforen. 2007 Sep 20;127(18):2386-7. Norwegian. PMID: 17941154.
  105. Greve G, Leirgul E. Takyarytmi og cor triatriatum [Tachyarrhythmia and cor triatriatum]. Tidsskr Nor Laegeforen. 2007 Apr 19;127(8):1058. Norwegian. PMID: 17469212.
  106. Markestad T. Begrensning av livsforlengende behandling [Life support care restriction]. Tidsskr Nor Laegeforen. 2008 Feb 14;128(4):476. Norwegian. PMID: 18274593.
  107. Hirth A, Disney P, Thorne S. Brain abscess associated with an unusual cause of right to left shunt. Heart. 2007 Jan;93(1):34. doi: 10.1136/hrt.2006.093773. PMID: 17170340; PMCID: PMC1861353.
  108. Thorsen PJ, Berg A, Hoff PI, Greve G. Risikofaktor for brå hjertedød ved lang QT-syndrom [Risk factors for sudden cardiac death related to the long QT syndrome]. Tidsskr Nor Laegeforen. 2006 Oct 5;126(19):2515-9. Norwegian. PMID: 17028631.
  109. Pesonen E, Johnsson J, Berg A. Intimal thickness of the coronary arteries in low-birthweight infants. Acta Paediatr. 2006 Oct;95(10):1234-8. doi: 10.1080/08035250600602992. PMID: 16982496.
  110. Vislie CH, Mikkelsen RB, Hoff PI, Greve G. Atrioventrikulaer nodal takykardi hos barn [Atrioventricular nodal reentry tachycardia in children]. Tidsskr Nor Laegeforen. 2006 Sep 21;126(18):2373-6. Norwegian. PMID: 16998549.
  111. Hirth A, Reybrouck T, Bjarnason-Wehrens B, Lawrenz W, Hoffmann A. Recommendations for participation in competitive and leisure sports in patients with congenital heart disease: a consensus document. Eur J Cardiovasc Prev Rehabil. 2006 Jun;13(3):293-9. doi: 10.1097/01.hjr.0000220574.22195.d6. PMID: 16926656.
  112. Midtbø H, Hirth A, Norgård G, Greve G. Trenger pasienter med ventrikkelseptumdefekt endokardittprofylakse? [Do patients with ventricular septal defect need endocarditis prophylaxis?]. Tidsskr Nor Laegeforen. 2005 Dec 1;125(23):3256-8. Norwegian. PMID: 16327848.
  113. Berg A, Søvik O, Hirth A. Vaeskebehandling og risiko for hjerneødem hos barn med diabetisk ketoacidose [Fluid management and the risk of cerebral oedema in children with diabetic ketoacidosis]. Tidsskr Nor Laegeforen. 2005 Nov 3;125(21):2932-5. Norwegian. PMID: 16276374.
  114. Pelliccia A, Fagard R, Bjørnstad HH, Anastassakis A, Arbustini E, Assanelli D, Biffi A, Borjesson M, Carrè F, Corrado D, Delise P, Dorwarth U, Hirth A, Heidbuchel H, Hoffmann E, Mellwig KP, Panhuyzen-Goedkoop N, Pisani A, Solberg EE, van-Buuren F, Vanhees L, Blomstrom-Lundqvist C, Deligiannis A, Dugmore D, Glikson M, Hoff PI, Hoffmann A, Hoffmann E, Horstkotte D, Nordrehaug JE, Oudhof J, McKenna WJ, Penco M, Priori S, Reybrouck T, Senden J, Spataro A, Thiene G; Study Group of Sports Cardiology of the Working Group of Cardiac Rehabilitation and Exercise Physiology; Working Group of Myocardial and Pericardial Diseases of the European Society of Cardiology. Recommendations for competitive sports participation in athletes with cardiovascular disease: a consensus document from the Study Group of Sports Cardiology of the Working Group of Cardiac Rehabilitation and Exercise Physiology and the Working Group of Myocardial and Pericardial Diseases of the European Society of Cardiology. Eur Heart J. 2005 Jul;26(14):1422-45. doi: 10.1093/eurheartj/ehi325. Epub 2005 May 27. PMID: 15923204.
  115. Berg A, Greve G, Hirth A, Rosland GA, Norgård G. Vurdering av barn med hjertebilyder [Evaluation of cardiac murmurs in children]. Tidsskr Nor Laegeforen. 2005 Apr 21;125(8):1000-3. Norwegian. PMID: 15852070.
  116. Norgård G, Greve G, Rosland GA, Berg A. Henvisningspraksis og klinisk vurdering av bilyder hos barn [Referral practice and clinical assessment of heart murmurs in children]. Tidsskr Nor Laegeforen. 2005 Apr 21;125(8):996-8. Norwegian. PMID: 15852069.
  117. Zadinello M, Greve G, Liu XQ, Barbosa JR Jr, Schulze-Neick I, Wilkinson JL, Redington AN. Angiotensin I converting enzyme genotype affects ventricular remodelling in children with aortic coarctation. Heart. 2005 Mar;91(3):367-8. doi: 10.1136/hrt.2003.026716. PMID: 15710723; PMCID: PMC1768784.
  118. Instebø A, Norgård G, Helgheim V, Røksund OD, Segadal L, Greve G. Exercise capacity in young adults with hypertension and systolic blood pressure difference between right arm and leg after repair of coarctation of the aorta. Eur J Appl Physiol. 2004 Oct;93(1-2):116-23. doi: 10.1007/s00421-004-1180-8. Epub 2004 Jul 28. PMID: 15549367.
  119. Lidén A, Berg A, Nedrebø T, Reed RK, Rubin K. Platelet-derived growth factor BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on beta3 but not beta1 integrins. Circ Res. 2006 Mar 17;98(5):635-41. doi: 10.1161/01.RES.0000207393.67851.d4. Epub 2006 Feb 2. PMID: 16456102.
  120. Chen RL, Penny DJ, Greve G, Lab MJ. Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambs. Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1008-14. doi: 10.1152/ajpheart.00724.2003. PMID: 14766676.
  121. Chen R, Penny DJ, Greve G, Lab MJ. Rate dependence of mechanically induced electrophysiological changes in right ventricle of anaesthetized lambs during pulmonary artery occlusion. Acta Physiol Scand. 2004 Jan;180(1):13-9. doi: 10.1046/j.0001-6772.2003.01201.x. PMID: 14706108.
  122. Markestad T. HLR minus og behandlingsunnlatelse [CPR and do-not-resuscitate orders]. Tidsskr Nor Laegeforen. 2003 Nov 20;123(22):3179. Norwegian. PMID: 14714002.
  123. Nedrebø T, Reed RK, Berg A. Effect of alpha-trinositol on interstitial fluid pressure, edema generation, and albumin extravasation after ischemia-reperfusion injury in rat hind limb. Shock. 2003 Aug;20(2):149-53. doi: 10.1097/01.shk.0000072128.33223.15. PMID: 12865659.
  124. Gray R, Greve G, Chen R, Fry C, Barron D, Lab MJ, White PA, Redington AN, Penny DJ. Right ventricular myocardial responses to chronic pulmonary regurgitation in lambs: disturbances of activation and conduction. Pediatr Res. 2003 Oct;54(4):529-35. doi: 10.1203/01.PDR.0000084829.67270.FA. Epub 2003 Jul 2. PMID: 12840148.
  125. Larsen TH, Taxt AM, Aslaksen A, Segadal L, Norgård G, Røksund OD, Greve G. Magnetic resonance imaging of patients with increased blood pressure and altered blood pressure response to exercise after coarctation repair. Scand Cardiovasc J. 2003 May;37(2):98-103. doi: 10.1080/14017430310001203. PMID: 12775309.
  126. Thomassen L, Waje-Andreassen U, Naess H, Hirth A, Russell D. Transkranial dopplersonografi, paradokse embolier og høyre-venstre-shunt [Transcranial Doppler sonography, paradoxical embolism and right-to-left shunt]. Tidsskr Nor Laegeforen. 2003 Mar 20;123(6):789-90. Norwegian. PMID: 12693116.
  127. Hirth A, Greve G, Rosland GA, Thomassen L, Norgård G. Kateterbasert lukking av åpentstående foramen ovale hos unge slagpasienter [Transcatheter closure of patent foramen ovale in young stroke patients]. Tidsskr Nor Laegeforen. 2003 Mar 20;123(6):785-8. Norwegian. PMID: 12693115.
  128. Rasmussen S, Albrechtsen S, Irgens LM, Dalaker K, Maartmann-Moe H, Vlatkovic L, Markestad T. Unexplained antepartum fetal death in Norway, 1985-97: diagnostic validation and some epidemiologic aspects. Acta Obstet Gynecol Scand. 2003 Feb;82(2):109-15. doi: 10.1034/j.1600-0412.2003.00009.x. PMID: 12648170.
  129. Rasmussen S, Albrechtsen S, Irgens LM, Dalaker K, Maartmann-Moe H, Vlatkovic L, Markestad T. Risk factors for unexplained antepartum fetal death in Norway 1967-1998. Early Hum Dev. 2003 Feb;71(1):39-52. doi: 10.1016/s0378-3782(02)00111-1. PMID: 12614949.
  130. Brønstad A, Reith A, Berg A, Reed RK. Effect of the cytoskeletal fixation agent phalloidin on transcapillary albumin transport and interstitial fluid pressure in anaphylaxis in the wistar rat. Microcirculation. 2002 Jul;9(3):197-205. doi: 10.1038/sj.mn.7800134. PMID: 12080417.
  131. Berg A, Norgård G, Greve G. Haemoptysis as a late complication of a Mustard operation treated by balloon dilation of a superior caval venous obstruction. Cardiol Young. 2002 May;12(3):298-301. doi: 10.1017/s1047951102000653. PMID: 12365182.
  132. Moster D, Lie RT, Markestad T. Neonatal mortality rates in communities with small maternity units compared with those having larger maternity units. BJOG. 2001 Sep;108(9):904-9. doi: 10.1111/j.1471-0528.2001.00207.x. PMID: 11563458.
  133. Greve G, Lab MJ, Chen R, Barron D, White PA, Redington AN, Penny DJ. Right ventricular distension alters monophasic action potential duration during pulmonary arterial occlusion in anaesthetised lambs: evidence for arrhythmogenic right ventricular mechanoelectrical feedback. Exp Physiol. 2001 Sep;86(5):651-7. doi: 10.1113/eph8602225. PMID: 11571494.
  134. Stewart M, Davidson K, Meade D, Hirth A, Weld-Viscount P. Group support for couples coping with a cardiac condition. J Adv Nurs. 2001 Jan;33(2):190-9. doi: 10.1046/j.1365-2648.2001.01652.x. PMID: 11168702.
  135. Baptista MJ, Fairbrother UL, Howard CM, Farrer MJ, Davies GE, Trikka D, Maratou K, Redington A, Greve G, Njølstad PR, Kessling AM. Heterotrisomy, a significant contributing factor to ventricular septal defect associated with Down syndrome? Hum Genet. 2000 Nov;107(5):476-82. doi: 10.1007/s004390000395. PMID: 11140945.
  136. Moster D, Markestad T, Lie RT. Assessing quality of obstetric care for low-risk deliveries; methodological problems in the use of population based mortality data. Acta Obstet Gynecol Scand. 2000 Jun;79(6):478-84. PMID: 10857872.
  137. Kvestad E, Lunde K, Markestad TJ, Førde R. Holdninger til behandling av ekstremt premature barn ved norske føde- og barneavdelinger [Attitudes towards treatment of extremely premature infants in Norwegian obstetric and pediatric departments]. Tidsskr Nor Laegeforen. 1999 Aug 30;119(20):3015-8. Norwegian. PMID: 10504852.
  138. Thu K, Segadal L, Kvitting P, Greve G. Pasienter operert for koarktasjon av aorta [Patients surgically treated for aortic coarctation]. Tidsskr Nor Laegeforen. 1999 Jun 10;119(15):2162-5. Norwegian. PMID: 10402908.
  139. Moster D, Lie RT, Markestad T. Relation between size of delivery unit and neonatal death in low risk deliveries: population based study. Arch Dis Child Fetal Neonatal Ed. 1999 May;80(3):F221-5. doi: 10.1136/fn.80.3.f221. PMID: 10212086; PMCID: PMC1720939.
  140. Larsen TH, Skar R, Frotjold EK, Haukanes K, Greve G, Saetersdal T. Regional activation of the immediate-early response gene c-fos in infarcted rat hearts. Int J Exp Pathol. 1998 Jun;79(3):163-72. doi: 10.1046/j.1365-2613.1998.00062.x. PMID: 9741358; PMCID: PMC3220382.
  141. Albrechtsen S, Rasmussen S, Reigstad H, Markestad T, Irgens LM, Dalaker K. Evaluation of a protocol for selecting fetuses in breech presentation for vaginal delivery or cesarean section. Am J Obstet Gynecol. 1997 Sep;177(3):586-92. doi: 10.1016/s0002-9378(97)70150-9. PMID: 9322628.
  142. Norgård G, Greve G, Hals J. Behandling av supraventrikulaer takykardi hos barn [Treatment of supraventricular tachycardia in children]. Tidsskr Nor Laegeforen. 1996 Oct 30;116(26):3124-9. Norwegian. PMID: 8999574.
  143. Reigstad H, Markestad T, Moster D. Høgfrekvent oscillering av nyfødde. Eit lovande behandlingsprinsipp ved vanskeleg respiratorbehandling [High-frequency oscillation in newborn infants. A promising therapeutic principle when respirator therapy is hazardous]. Tidsskr Nor Laegeforen. 1994 Jun 30;114(17):1925-7. Norwegian. PMID: 8079316.
  144. Greve G, Bachinski L, Friedman DL, Czernuzewicz G, Anan R, Towbin J, Seidman CE, Roberts R. Isolation of a de novo mutant myocardial beta MHC protein in a pedigree with hypertrophic cardiomyopathy. Hum Mol Genet. 1994 Nov;3(11):2073-5. PMID: 7874131.
  145. Anan R, Greve G, Thierfelder L, Watkins H, McKenna WJ, Solomon S, Vecchio C, Shono H, Nakao S, Tanaka H, et al. Prognostic implications of novel beta cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy. J Clin Invest. 1994 Jan;93(1):280-5. doi: 10.1172/JCI116957. PMID: 8282798; PMCID: PMC293763.
  146. Larsen TH, Hesketh JE, Rotevatn S, Greve G, Saetersdal T. Ribosome distribution in normal and infarcted rat hearts. Histochem J. 1994 Jan;26(1):79-89. PMID: 8169153.
  147. Marian AJ, Yu QT, Workman R, Greve G, Roberts R. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet. 1993 Oct 30;342(8879):1085-6. doi: 10.1016/0140-6736(93)92064-z. PMID: 8105312.
  148. Markestad T. Transport av syke nyfødte [Transport of ill newborn infants]. Tidsskr Nor Laegeforen. 1993 Sep 10;113(21):2673-4. Norwegian. PMID: 8266285.
  149. Haram K, Reigstad H, Markestad T. Prenatal forebygging av åndenødssyndrom hos nyfødte [Prenatal prevention of respiratory distress syndrome in newborn infants]. Tidsskr Nor Laegeforen. 1993 May 30;113(14):1698-700. Norwegian. PMID: 8322294.
  150. Greve G, Bakøy OE, Holten T, Jynge P, Saetersdal T. Reversibility of mild to moderate ischemic injuries in the isolated rat heart. A characterization by 31P-NMR and by physiological and ultrastructural indices. Am J Pathol. 1993 Apr;142(4):1279-89. PMID: 8475998; PMCID: PMC1886880.
  151. Skadberg BT, Faerestrand S, Ohm OJ. Intermitterende bradyarytmi i sped- og småbarnsalderen behandlet med permanent pacemaker [Intermittent bradyarrhythmia in infants and small children treated with permanent pacemaker]. Tidsskr Nor Laegeforen. 1992 Apr 30;112(11):1436-40. Norwegian. PMID: 1631815.
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Immunological aspects in acute and chronic disease

Immunological processes as consequences of infections or/and autoimmunity causes disease are of great importance in childhood.

 

PhD dissertations:

 

Peer review publications:

  1. Arneng SM, Jenssen IP, Lundestad A, Cetrelli L, Angenete O, Nordal E, Tylleskär KB, Romundstad PR, Rygg M. The patient's voice: a cross-sectional study of physical health and disability in juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2024 Nov 18;22(1):100. doi: 10.1186/s12969-024-01034-7. PMID: 39558411; PMCID: PMC11572323.
  2. Bredholt G, Sævik M, Søyland H, Ueland T, Zhou F, Pathirana R, Madsen A, Vahokoski J, Lartey S, Halvorsen BE, Dahl TB, Trieu MC, Mohn KG, Brokstad KA, Aukrust P, Tøndel C, Langeland N, Blomberg B, Cox RJ; Bergen COVID-19 Research Group. Three doses of Sars-CoV-2 mRNA vaccine in older adults result in similar antibody responses but reduced cellular cytokine responses relative to younger adults. Vaccine X. 2024 Sep 25;20:100564. doi: 10.1016/j.jvacx.2024.100564. PMID: 39403561; PMCID: PMC11472110.
  3. Cetrelli L, Lundestad A, Gil EG, Fischer J, Halbig J, Frid P, Angenete O, Rosén A, Tylleskär KB, Luukko K, Nordal E, Åstrøm AN, Skeie MS, Stunes AK, Bletsa A, Sen A, Feuerherm AJ, Rygg M. Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis-an explorative cross-sectional study. Pediatr Rheumatol Online J. 2024 Mar 9;22(1):36. doi: 10.1186/s12969-024-00972-6. PMID: 38461338; PMCID: PMC10924355.
  4. Varpula R, Äyräs O, Aabakke AJM, Klungsøyr K, Svanvik T, Kanerva J, Jonasdottir E, Mentzoni CT, Thurn L, Jones E, Fredriksson L, Pettersson K, Nyfløt LT, Vangen S, Røe K, Júlíusson PB, Källén K, Gissler M, Pyykönen A, Jakobsson M, Krebs L, Engjom HM. Early suppression policies protected pregnant women from COVID-19 in 2020: A population-based surveillance from the Nordic countries. Acta Obstet Gynecol Scand. 2024 Jun;103(6):1063-1072. doi: 10.1111/aogs.14808. Epub 2024 Feb 21. PMID: 38382894; PMCID: PMC11103151.
  5. Zhou F, Vahokoski J; Bergen COVID-19 Research Group; Langeland N, Cox RJ. Impact of ageing on homologous and human-coronavirus-reactive antibodies after SARS-CoV-2 vaccination or infection. NPJ Vaccines. 2024 Feb 20;9(1):37. doi: 10.1038/s41541-024-00817-z. PMID: 38378953; PMCID: PMC10879087.
  6. Varpula R, Äyräs O, Aabakke AJM, Klungsøyr K, Svanvik T, Kanerva J, Jonasdottir E, Mentzoni CT, Thurn L, Jones E, Fredriksson L, Pettersson K, Nyfløt LT, Vangen S, Røe K, Júlíusson PB, Källén K, Gissler M, Pyykönen A, Jakobsson M, Krebs L, Engjom HM. Early suppression policies protected pregnant women from COVID-19 in 2020: A population-based surveillance from the Nordic countries. Acta Obstet Gynecol Scand. 2024 Jun;103(6):1063-1072. doi: 10.1111/aogs.14808. Epub 2024 Feb 21. PMID: 38382894; PMCID: PMC11103151.
  7. Norman M, Magnus MC, Söderling J, Juliusson PB, Navér L, Örtqvist AK, Håberg S, Stephansson O. Neonatal Outcomes After COVID-19 Vaccination in Pregnancy. JAMA. 2024 Feb 6;331(5):396-407. doi: 10.1001/jama.2023.26945. PMID: 38319332; PMCID: PMC10848052.
  8. Ludvigsson JF, Håberg SE, Juliusson PB, Andersen AN, Urhoj SK, Stephansson O. Three Scandinavian countries did not see the same increase in foetal situs inversus observed in China during the COVID-19 pandemic. Acta Paediatr. 2024 Apr;113(4):751-752. doi: 10.1111/apa.17141. Epub 2024 Feb 3. PMID: 38308485.
  9. Raknes G, Fagerås SJ, Sveen KA, Júlíusson PB, Strøm MS. Excess non-COVID-19 mortality in Norway 2020-2022. BMC Public Health. 2024 Jan 22;24(1):244. doi: 10.1186/s12889-023-17515-5. PMID: 38254068; PMCID: PMC10801945.
  10. Onyango TB, Zhou F, Bredholt G, Brokstad KA, Lartey S, Mohn KG, Özgümüs T, Kittang BR, Linchausen DW, Shafiani S, Elyanow R, Blomberg B, Langeland N, Cox RJ; Bergen COVID-19 Research Group. SARS-CoV-2 specific immune responses in overweight and obese COVID-19 patients. Front Immunol. 2023 Nov 2;14:1287388. doi: 10.3389/fimmu.2023.1287388. PMID: 38022529; PMCID: PMC10653322.
  11. Huncikova Z, Stensvold HJ, Øymar KAA, Vatne A, Lang AM, Støen R, Brigtsen AK, Moster D, Eriksen BH, Selberg T, Rønnestad A, Klingenberg C. Variation in antibiotic consumption in very preterm infants-a 10 year population-based study. J Antimicrob Chemother. 2024 Jan 3;79(1):143-150. doi: 10.1093/jac/dkad358. PMID: 37986613; PMCID: PMC10761275.
  12. Huncikova Z, Vatne A, Stensvold HJ, Lang AM, Støen R, Brigtsen AK, Salvesen B, Øymar KAA, Rønnestad A, Klingenberg C; Norwegian Neonatal Network. Late-onset sepsis in very preterm infants in Norway in 2009-2018: a population-based study. Arch Dis Child Fetal Neonatal Ed. 2023 Sep;108(5):478-484. doi: 10.1136/archdischild-2022-324977. Epub 2023 Feb 2. PMID: 36732047; PMCID: PMC10447404.
  13. Thaulow CM, Klingenberg C. C.H. Thaulow og C. Klingenberg svarer. Tidsskr Nor Laegeforen. 2023 Sep 4;143(12). Norwegian. doi: 10.4045/tidsskr.23.0535. PMID: 37668122.
  14. Bansal A, Trieu MC, Mohn KGI, Madsen A, Olofsson JS, Sandnes HH, Sævik M, Søyland H, Hansen L, Onyango TB, Tøndel C, Brokstad KA; Bergen COVID-19 research group; Syre H, Riis ÅG, Langeland N, Cox RJ. Risk assessment and antibody responses to SARS-CoV-2 in healthcare workers. Front Public Health. 2023 Jul 21;11:1164326. doi: 10.3389/fpubh.2023.1164326. PMID: 37546332; PMCID: PMC10402899.
  15. Thaulow CM, Klingenberg C. Penicillin for enhver pris? Tidsskr Nor Laegeforen. 2023 Jun 26;143(10). Norwegian. doi: 10.4045/tidsskr.23.0172. PMID: 37376941.
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  79. Mikalsen IB, Halvorsen T, Øymar K. The outcome after severe bronchiolitis is related to gender and virus. Pediatr Allergy Immunol. 2012 Jun;23(4):391-8. doi: 10.1111/j.1399-3038.2012.01283.x. Epub 2012 Mar 22. PMID: 22435682.
  80. Tveitnes D, Natås OB, Skadberg Ø, Øymar K. Lyme meningitis, the major cause of childhood meningitis in an endemic area: a population based study. Arch Dis Child. 2012 Mar;97(3):215-20. doi: 10.1136/archdischild-2011-300526. Epub 2012 Jan 13. PMID: 22247243.
  81. Tveitnes D, Natås OB, Skadberg Ø, Øymar K. Lyme meningitis, the major cause of childhood meningitis in an endemic area: a population based study. Arch Dis Child. 2012 Mar;97(3):215-20. doi: 10.1136/archdischild-2011-300526. Epub 2012 Jan 13. PMID: 22247243.
  82. Øymar K. Bruk av inhalasjonssteroider hos førskolebarn [The use of inhaled corticosteroids in preschool children]. Tidsskr Nor Laegeforen. 2012 Jan 24;132(2):160-2. Norwegian. doi: 10.4045/tidsskr.10.0742. PMID: 22278273.
  83. Valovirta E, Berstad AK, de Blic J, Bufe A, Eng P, Halken S, Ojeda P, Roberts G, Tommerup L, Varga EM, Winnergard I; GAP investigators. Design and recruitment for the GAP trial, investigating the preventive effect on asthma development of an SQ-standardized grass allergy immunotherapy tablet in children with grass pollen-induced allergic rhinoconjunctivitis. Clin Ther. 2011 Oct;33(10):1537-46. doi: 10.1016/j.clinthera.2011.09.013. Epub 2011 Oct 13. PMID: 21999887.
  84. Flagstad G, Helgeland H, Markestad T. Faecal calprotectin concentrations in children with functional gastrointestinal disorders diagnosed according to the Pediatric Rome III criteria. Acta Paediatr. 2010 May;99(5):734-737. doi: 10.1111/j.1651-2227.2010.01698.x. Epub 2010 Mar 5. PMID: 20219041.
  85. Gilje AM, Knudsen PK, Øymar K. Ei ung jente med magesmerter [A young girl with abdominal pain]. Tidsskr Nor Laegeforen. 2011 Jun 17;131(12):1199-201. Norwegian. doi: 10.4045/tidsskr.09.0887. PMID: 21694748.
  86. Tveitnes D, Øymar K, Natås O. Laboratory data in children with Lyme neuroborreliosis, relation to clinical presentation and duration of symptoms. Scand J Infect Dis. 2009;41(5):355-62. doi: 10.1080/00365540902787666. PMID: 19253089.
  87. Øymar K, Tveitnes D. Clinical characteristics of childhood Lyme neuroborreliosis in an endemic area of northern Europe. Scand J Infect Dis. 2009;41(2):88-94. doi: 10.1080/00365540802593453. PMID: 19065451.
  88. Hagen I, Øymar K. Pharmacological differences between once daily and twice daily gentamicin dosage in newborns with suspected sepsis. Pharm World Sci. 2009 Feb;31(1):18-23. doi: 10.1007/s11096-008-9255-y. Epub 2008 Nov 4. PMID: 18982422.
  89. Berg A, Furu K, Spigset O. Slimhinneavsvellende nesedråper og nesespray hos barn [Nasal decongestants and nasal sprays in children]. Tidsskr Nor Laegeforen. 2008 Nov 20;128(22):2582-3. Norwegian. PMID: 19023356.
  90. Øymar K, Tveitnes D. Økt forekomst av nevroborreliose hos barn [Increase in childhood neuroborreliosis]. Tidsskr Nor Laegeforen. 2008 Sep 25;128(18):2060-1. Norwegian. PMID: 18846121.
  91. Busse WW, Pedersen S, Pauwels RA, Tan WC, Chen YZ, Lamm CJ, O'Byrne PM; START Investigators Group. The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: effectiveness of early intervention with budesonide in mild persistent asthma. J Allergy Clin Immunol. 2008 May;121(5):1167-74. doi: 10.1016/j.jaci.2008.02.029. Epub 2008 Apr 11. PMID: 18405951.
  92. Byberg K, Øymar K, Aksnes L. Fatty acids in cord blood plasma, the relation to soluble CD23 and subsequent atopy. Prostaglandins Leukot Essent Fatty Acids. 2008 Jan;78(1):61-5. doi: 10.1016/j.plefa.2007.10.008. Epub 2007 Dec 3. PMID: 18060752.
  93. Førsvoll JA, Øymar K. C-reactive protein in the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. Acta Paediatr. 2007 Nov;96(11):1670-3. doi: 10.1111/j.1651-2227.2007.00499.x. PMID: 17937691.
  94. Klingenberg C, Skadberg B. Hvordan blir nyansatte leger tatt imot på barneavdelingene? [Orientation programme for paediatric residents]. Tidsskr Nor Laegeforen. 2007 Aug 23;127(16):2105-8. Norwegian. PMID: 17717576.
  95. Øymar K, Røsvik A, Fossheim J, Kjellerød C, El-Saggan A. Regelmessige episoder med høy feber hos en liten gutt [Recurrent fever episodes in a small boy]. Tidsskr Nor Laegeforen. 2007 Jun 14;127(12):1662-3. Norwegian. PMID: 17615623.
  96. Øymar K, Kristoffersen EK. Periodisk feber-syndrom hos barn [Periodic fever syndrome in children]. Tidsskr Nor Laegeforen. 2007 Jun 14;127(12):1651-3. Norwegian. PMID: 17571105.
  97. Tveitnes D, Øymar K, Natås O. Acute facial nerve palsy in children: how often is it lyme borreliosis? Scand J Infect Dis. 2007;39(5):425-31. doi: 10.1080/00365540601105764. PMID: 17464865.
  98. Øymar K. Allergivaksinasjon i Norge [Allergy vaccination in Norway]. Tidsskr Nor Laegeforen. 2007 Apr 19;127(8):1036-8. Norwegian. PMID: 17457388.
  99. Steinsvåg SK, Skadberg B, Bredesen K. Nasal symptoms and signs in children suffering from asthma. Int J Pediatr Otorhinolaryngol. 2007 Apr;71(4):615-21. doi: 10.1016/j.ijporl.2006.12.012. Epub 2007 Feb 2. PMID: 17275928.
  100. Fleming DM, Crovari P, Wahn U, Klemola T, Schlesinger Y, Langussis A, Øymar K, Garcia ML, Krygier A, Costa H, Heininger U, Pregaldien JL, Cheng SM, Skinner J, Razmpour A, Saville M, Gruber WC, Forrest B; CAIV-T Asthma Study Group. Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma. Pediatr Infect Dis J. 2006 Oct;25(10):860-9. doi: 10.1097/01.inf.0000237797.14283.cf. PMID: 17006278.
  101. O'Byrne PM, Pedersen S, Busse WW, Tan WC, Chen YZ, Ohlsson SV, Ullman A, Lamm CJ, Pauwels RA; START Investigators Group. Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma. Chest. 2006 Jun;129(6):1478-85. doi: 10.1378/chest.129.6.1478. PMID: 16778264.
  102. Lidén A, Berg A, Nedrebø T, Reed RK, Rubin K. Platelet-derived growth factor BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on beta3 but not beta1 integrins. Circ Res. 2006 Mar 17;98(5):635-41. doi: 10.1161/01.RES.0000207393.67851.d4. Epub 2006 Feb 2. PMID: 16456102.
  103. Øymar K, Halvorsen T, Aksnes L. Mast cell activation and leukotriene secretion in wheezing infants. Relation to respiratory syncytial virus and outcome. Pediatr Allergy Immunol. 2006 Feb;17(1):37-42. doi: 10.1111/j.1399-3038.2005.00345.x. PMID: 16426253.
  104. Aurivillius M, Øymar K, Oxelius VA. Immunoglobulin heavy G2 chain (IGHG2) gene restriction in the development of severe respiratory syncytial virus infection. Acta Paediatr. 2005 Apr;94(4):414-8. doi: 10.1111/j.1651-2227.2005.tb01910.x. PMID: 16092453.
  105. Rønnestad A, Abrahamsen TG, Medbø S, Reigstad H, Lossius K, Kaaresen PI, Engelund IE, Irgens LM, Markestad T. Septicemia in the first week of life in a Norwegian national cohort of extremely premature infants. Pediatrics. 2005 Mar;115(3):e262-8. doi: 10.1542/peds.2004-1834. Epub 2005 Feb 1. PMID: 15687417.
  106. Rønnestad A, Abrahamsen TG, Medbø S, Reigstad H, Lossius K, Kaaresen PI, Egeland T, Engelund IE, Irgens LM, Markestad T. Late-onset septicemia in a Norwegian national cohort of extremely premature infants receiving very early full human milk feeding. Pediatrics. 2005 Mar;115(3):e269-76. doi: 10.1542/peds.2004-1833. Epub 2005 Feb 1. PMID: 15687416.
  107. Øymar K, Aksnes L. Increased levels of urinary leukotriene E4 in children with severe atopic eczema/dermatitis syndrome. Allergy. 2005 Jan;60(1):86-9. doi: 10.1111/j.1398-9995.2005.00658.x. PMID: 15575936.
  108. Øymar K, Aksnes L. Urinary 9alpha,11beta-prostaglandin F(2) in children with atopic eczema/dermatitis syndrome: an indicator of mast cell activation? Acta Derm Venereol. 2004;84(5):359-62. doi: 10.1080/00015550410035515. PMID: 15370701.
  109. Daltveit AK, Irgens LM, Oyen N, Skjaerven R, Markestad T, Wennergren G. Circadian variations in sudden infant death syndrome: associations with maternal smoking, sleeping position and infections. The Nordic Epidemiological SIDS Study. Acta Paediatr. 2003 Sep;92(9):1007-13. PMID: 14599060.
  110. Ellingsen BB, Aase SA, Øymar K. Forebygging av respiratorisk syncytialvirus-infeksjoner med palivizumab [Prevention of respiratory syncytial virus infections with palivizumab]. Tidsskr Nor Laegeforen. 2003 Apr 3;123(7):941-3. Norwegian. PMID: 12737068.
  111. Pauwels RA, Pedersen S, Busse WW, Tan WC, Chen YZ, Ohlsson SV, Ullman A, Lamm CJ, O'Byrne PM; START Investigators Group. Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet. 2003 Mar 29;361(9363):1071-6. doi: 10.1016/S0140-6736(03)12891-7. PMID: 12672309.
  112. Estil S, Kravik K, Haaskjold E, Refsum SB, Bjerknes R, Wilson G. Pilot study on the time course of apoptosis in the regenerating corneal epithelium. Acta Ophthalmol Scand. 2002 Oct;80(5):517-23. doi: 10.1034/j.1600-0420.2002.800511.x. PMID: 12390164.
  113. Markestad T, Reigstad H. Screening for alloimmun trombocytopeni [Screening for alloimmune thrombocytopenia]. Tidsskr Nor Laegeforen. 2002 Feb 28;122(6):650; author reply 650-1. Norwegian. PMID: 11998723.
  114. Hestholm F, Morken T, Skadberg BT, Berg A. Urticaria og angioødem hos barn [Urticaria and angioedema in children]. Tidsskr Nor Laegeforen. 2002 Feb 28;122(6):610-4. Norwegian. PMID: 11998713.
  115. Øymar K. High levels of urinary eosinophil protein X in young asthmatic children predict persistent atopic asthma. Pediatr Allergy Immunol. 2001 Dec;12(6):312-7. doi: 10.1034/j.1399-3038.2001.0o080.x. PMID: 11846868.
  116. Øymar K, Havnen J, Halvorsen T, Bjerknes R. Eosinophil counts and urinary eosinophil protein X in children hospitalized for wheezing during the first year of life: prediction of recurrent wheezing. Acta Paediatr. 2001 Aug;90(8):843-9. PMID: 11529528.
  117. Estil S, Haaskjold E, Bjerknes R, Refsum SB. A previous abrasion in the contralateral eye influences the cell kinetics during healing of a central corneal abrasion. Acta Ophthalmol Scand. 2001 Aug;79(4):389-93. doi: 10.1034/j.1600-0420.2001.079004389.x. PMID: 11453860.
  118. Skadberg BT, Berstad AK. "Snørr og øreverk"--en plage for barnet, en byrde for samfunnet ["Runny nose and earache"--a torment for the child, a burden for the community]. Tidsskr Nor Laegeforen. 2001 Apr 30;121(11):1328. Norwegian. PMID: 11419099.
  119. Júlíusson PB, Bjerknes R, Søvik O, Kvistad PH. Generaliserte ødemer ved insulinbehandling av nyoppdaget diabetes mellitus [Generalized edema following insulin treatment of newly diagnosed diabetes mellitus]. Tidsskr Nor Laegeforen. 2001 Mar 20;121(8):919-20. Norwegian. PMID: 11332378.
  120. Øymar K, Bjerknes R. Urinary eosinophil protein X in children with asthma: influence of atopy and airway infections. Pediatr Allergy Immunol. 2001 Feb;12(1):34-41. doi: 10.1034/j.1399-3038.2001.012001034.x. PMID: 11251863.
  121. Markestad T. Tilnaerming til det akutt syke barnet [Approaching the acutely ill child]. Tidsskr Nor Laegeforen. 2001 Feb 20;121(5):608-11. Norwegian. PMID: 11301620.
  122. Øymar K, Laerdal A, Bjerknes R. Soluble CD30 and CD23 in cord blood are not related to atopy in early childhood. Pediatr Allergy Immunol. 2000 Nov;11(4):220-4. doi: 10.1034/j.1399-3038.2000.00094.x. PMID: 11110575.
  123. Øymar K, Bjerknes R. Urinary eosinophil protein X in children with atopic dermatitis: relation to atopy and disease activity. Allergy. 2000 Oct;55(10):964-8. doi: 10.1034/j.1398-9995.2000.00682.x. PMID: 11030379.
  124. Øymar K. Bakteriell trakeitt hos barn [Bacterial tracheitis in children]. Tidsskr Nor Laegeforen. 2000 May 10;120(12):1417-9. Norwegian. PMID: 10851938.
  125. Helweg-Larsen K, Lundemose JB, Oyen N, Skjaerven R, Alm B, Wennergren G, Markestad T, Irgens LM. Interactions of infectious symptoms and modifiable risk factors in sudden infant death syndrome. The Nordic Epidemiological SIDS study. Acta Paediatr. 1999 May;88(5):521-7. doi: 10.1080/08035259950169521. PMID: 10426174.
  126. Frostad S, Bjerknes R, Hervig T, Nesthus I, Olweus J, Bruserud Ø Ø. Malignancy: Insulin-like Growth Factor-1 (IGF-1) is a Costimulator of the Expansion of Lineage Committed Cells Derived from Peripheral Blood Mobilized CD34+ Cells in Multiple Myeloma Patients. Hematology. 1999;4(3):217-229. PMID: 11399566.
  127. Frostad S, Bjerknes R, Hervig T, Nesthus I, Olweus J, Bruserud Ø. Insulin-like Growth Factor-1 (IGF-1) is a Costimulator of the Expansion of Lineage Committed Cells Derived from Peripheral Blood Mobilized CD34(+) Cells in Multiple Myeloma Patients. Hematology. 1999;4(3):217-29. doi: 10.1080/10245332.1999.11746445. PMID: 27420550.
  128. Juliusson PB, Helgason H, Thorsson AV. [Kawasaki disease in Iceland 1979-1997.]. Laeknabladid. 1999 Feb;85(2):120-94. Icelandic. PMID: 19321916.
  129. Røsok BI, Brinchmann JE, Stent G, Bjerknes R, Voltersvik P, Olofsson J, Asjö B. Correlates of apoptosis of CD4+ and CD8+ T cells in tonsillar tissue in HIV type 1 infection. AIDS Res Hum Retroviruses. 1998 Dec 20;14(18):1635-43. doi: 10.1089/aid.1998.14.1635. PMID: 9870316.
  130. Sandboe FD, Medin W, Bjerknes R. Toxicity of vancomycin on corneal endothelium in rabbits. Acta Ophthalmol Scand. 1998 Dec;76(6):675-8. doi: 10.1034/j.1600-0420.1998.760608.x. PMID: 9881550.
  131. Vesterhus P, Holland SM, Abrahamsen TG, Bjerknes R. Familial disseminated infection due to atypical mycobacteria with childhood onset. Clin Infect Dis. 1998 Oct;27(4):822-5. doi: 10.1086/514939. PMID: 9798040.
  132. Eikeset K, Markestad T. Tarminvaginasjon hjå barn i Hordaland fylke 1983-92 [Intestinal invagination in children in the county of Hordaland 1983-92]. Tidsskr Nor Laegeforen. 1998 Nov 10;118(27):4197-9. Norwegian. PMID: 9857801.
  133. Frostad S, Bjerknes R, Abrahamsen JF, Olweus J, Bruserud O. Insulin-like growth factor-1 (IGF-1) has a costimulatory effect on proliferation of committed progenitors derived from human umbilical cord CD34+ cells. Stem Cells. 1998;16(5):334-42. doi: 10.1002/stem.160334. PMID: 9766813.
  134. Øymar K, Bjerknes R. Is serum eosinophil cationic protein in bronchiolitis a predictor of asthma? Pediatr Allergy Immunol. 1998 Nov;9(4):204-7. doi: 10.1111/j.1399-3038.1998.tb00374.x. PMID: 9920219.
  135. Vindenes HA, Ulvestad E, Bjerknes R. Concentrations of cytokines in plasma of patients with large burns: their relation to time after injury, burn size, inflammatory variables, infection, and outcome. Eur J Surg. 1998 Sep;164(9):647-56. doi: 10.1080/110241598750005525. PMID: 9728783.
  136. Øymar K, Bjerknes R. Differential patterns of circulating adhesion molecules in children with bronchial asthma and acute bronchiolitis. Pediatr Allergy Immunol. 1998 May;9(2):73-9. doi: 10.1111/j.1399-3038.1998.tb00307.x. PMID: 9677602.
  137. Alm B, Milerad J, Wennergren G, Skjaerven R, Oyen N, Norvenius G, Daltveit AK, Helweg-Larsen K, Markestad T, Irgens LM. A case-control study of smoking and sudden infant death syndrome in the Scandinavian countries, 1992 to 1995. The Nordic Epidemiological SIDS Study. Arch Dis Child. 1998 Apr;78(4):329-34. doi: 10.1136/adc.78.4.329. PMID: 9623395; PMCID: PMC1717534.
  138. Daltveit AK, Irgens LM, Oyen N, Skjaerven R, Markestad T, Alm B, Wennergren G, Norvenius G, Helweg-Larsen K. Sociodemographic risk factors for sudden infant death syndrome: associations with other risk factors. The Nordic Epidemiological SIDS Study. Acta Paediatr. 1998 Mar;87(3):284-90. doi: 10.1080/08035259850157336. PMID: 9560035.
  139. Ryan M, Murphy G, Ryan E, Nilsson L, Shackley F, Gothefors L, Øymar K, Miller E, Storsaeter J, Mills KH. Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children. Immunology. 1998 Jan;93(1):1-10. doi: 10.1046/j.1365-2567.1998.00401.x. PMID: 9536112; PMCID: PMC1364099.
  140. Skadberg BT, Morild I, Markestad T. Abandoning prone sleeping: Effect on the risk of sudden infant death syndrome. J Pediatr. 1998 Feb;132(2):340-3. doi: 10.1016/s0022-3476(98)70456-1. PMID: 9506652.
  141. Wennergren G, Alm B, Oyen N, Helweg-Larsen K, Milerad J, Skjaerven R, Norvenius SG, Lagercrantz H, Wennborg M, Daltveit AK, Markestad T, Irgens LM. The decline in the incidence of SIDS in Scandinavia and its relation to risk-intervention campaigns. Nordic Epidemiological SIDS Study. Acta Paediatr. 1997 Sep;86(9):963-8. doi: 10.1111/j.1651-2227.1997.tb15180.x. PMID: 9343276.
  142. Øyen N, Markestad T, Skaerven R, Irgens LM, Helweg-Larsen K, Alm B, Norvenius G, Wennergren G. Combined effects of sleeping position and prenatal risk factors in sudden infant death syndrome: the Nordic Epidemiological SIDS Study. Pediatrics. 1997 Oct;100(4):613-21. doi: 10.1542/peds.100.4.613. PMID: 9310514.
  143. Skadberg BT, Markestad T. Consequences of getting the head covered during sleep in infancy. Pediatrics. 1997 Aug;100(2):E6. doi: 10.1542/peds.100.2.e6. PMID: 9233977.
  144. Øymar K, Svihus R. Diskitt hos barn. Beskrivelse av tilstanden belyst ved to pasienter [Discitis in children. Description of the condition illustrated by two case reports]. Tidsskr Nor Laegeforen. 1997 Jun 10;117(15):2184-6. Norwegian. PMID: 9235708.
  145. Vindenes HA, Bjerknes R. Impaired actin polymerization and depolymerization in neutrophils from patients with thermal injury. Burns. 1997 Mar;23(2):131-6. doi: 10.1016/s0305-4179(96)00121-0. PMID: 9177879.
  146. Steinsvåg SK, Bjerknes R, Berg OH. Effects of topical nasal steroids on human respiratory mucosa and human granulocytes in vitro. Acta Otolaryngol. 1996 Nov;116(6):868-75. doi: 10.3109/00016489609137943. PMID: 8973724.
  147. Øymar K, Elsayed S, Bjerknes R. Serum eosinophil cationic protein and interleukin-5 in children with bronchial asthma and acute bronchiolitis. Pediatr Allergy Immunol. 1996 Nov;7(4):180-6. doi: 10.1111/j.1399-3038.1996.tb00130.x. PMID: 9151339.
  148. Røsok BI, Bostad L, Voltersvik P, Bjerknes R, Olofsson J, Asjö B, Brinchmann JE. Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection. AIDS. 1996 Sep;10(10):F35-8. PMID: 8874620.
  149. Røsok B, Voltersvik P, Bjerknes R, Axelsson M, Haaheim LR, Asjö B. Dynamics of HIV-1 replication following influenza vaccination of HIV+ individuals. Clin Exp Immunol. 1996 May;104(2):203-7. doi: 10.1046/j.1365-2249.1996.25732.x. Erratum in: Clin Exp Immunol 1996 Sep;105(3):561. PMID: 8625509; PMCID: PMC2200426.
  150. Vindenes H, Bjerknes R. Microbial colonization of large wounds. Burns. 1995 Dec;21(8):575-9. doi: 10.1016/0305-4179(95)00047-f. PMID: 8747728.
  151. Vindenes H, Ulvestad E, Bjerknes R. Increased levels of circulating interleukin-8 in patients with large burns: relation to burn size and sepsis. J Trauma. 1995 Oct;39(4):635-40. doi: 10.1097/00005373-199510000-00003. PMID: 7473946.
  152. Bjerknes R, Aarskog D. Priming of human polymorphonuclear neutrophilic leukocytes by insulin-like growth factor I: increased phagocytic capacity, complement receptor expression, degranulation, and oxidative burst. J Clin Endocrinol Metab. 1995 Jun;80(6):1948-55. doi: 10.1210/jcem.80.6.7775645. PMID: 7775645.
  153. Øyen N, Irgens LM, Skjaerven R, Morild I, Markestad T, Rognum TO. Secular trends of sudden infant death syndrome in Norway 1967-1988: application of a method of case identification to Norwegian registry data. Paediatr Perinat Epidemiol. 1994 Jul;8(3):263-81. doi: 10.1111/j.1365-3016.1994.tb00460.x. PMID: 7997403.
  154. Øymar K, Fluge G, Rosendahl K. Residiverende abdominalsmerter. En prospektiv undersøkelse av 68 barn [Recurrent abdominal pain. A prospective study of 68 children]. Tidsskr Nor Laegeforen. 1993 Aug 30;113(20):2566-8. Norwegian. PMID: 8236176.
  155. Reigstad H, Bjerknes R, Markestad T, Myrmel H. Ganciclovir therapy of congenital cytomegalovirus disease. Acta Paediatr. 1992 Sep;81(9):707-8. doi: 10.1111/j.1651-2227.1992.tb12341.x. PMID: 1330115.
  156. Markestad T, Grønlie I. Propylenglykol i medikamenter. Risiko for spedbarn? [Propylene glycol in drugs. Risk for infants?]. Tidsskr Nor Laegeforen. 1992 Jan 20;112(2):260. Norwegian. PMID: 1566269.
  157. Moster D. Epidermolysis bullosa gravis Herlitz. En utfordring for en barneavdeling [Epidermolysis bullosa gravis Herlitz. A challenge for a pediatric department]. Tidsskr Nor Laegeforen. 1991 Nov 30;111(29):3499-501. Norwegian. PMID: 1796434.
  158. Haram K, Markestad T, Haukenes G. Herpes genitalis i svangerskapet. Tid for nye tilrådinger? [Genital herpes in pregnancy. Time for new advice?]. Tidsskr Nor Laegeforen. 1990 Jan 20;110(2):225-7. Norwegian. PMID: 2300960.
  159. Reigstad H, Markestad T, Gjengstø H. Behandling av alvorleg septikemi og meningitt hos småborn [Treatment of severe septicemia and meningitis in children]. Tidsskr Nor Laegeforen. 1988 Aug 30;108(24):1925-7. Norwegian. PMID: 3206407.
  160. Myrmel H, Haram K, Markestad T. Infeksjoner hos gravide og nyfødte forårsaket av cytomegalovirus [Infections in pregnant women and newborn infants caused by cytomegaloviruses]. Tidsskr Nor Laegeforen. 1987 Mar 20;107(8):730-1. Norwegian. PMID: 3033840.
  161. Quinn PA, Gillan JE, Markestad T, St John MA, Daneman A, Lie KI, Li HC, Czegledy-Nagy E, Klein A. Intrauterine infection with Ureaplasma urealyticum as a cause of fatal neonatal pneumonia. Pediatr Infect Dis. 1985 Sep-Oct;4(5):538-43. doi: 10.1097/00006454-198509000-00020. PMID: 3900948.
  162. Markestad T, Finne PH, Digranes A. Infeksjoner hos spedbarn forårsaket av gruppe B-streptokokker [Neonatal infections caused by Group B streptococci]. Tidsskr Nor Laegeforen. 1981 Aug 10;101(22):1187-9. Norwegian. PMID: 7025345

 

Neurological and mental health in children

Neurological and mental consequenses of premature birth and disease in childhood.

 

PhD dissertations:

Peer review publications:

  1. Benum SD, Aakvik KAD, Mehl CV, Kongsvold A, Lydersen S, Vollsæter M, Mork PJ, Kajantie E, Evensen KAI. Device-measured physical activity in adults born preterm with very low birth weight and mediation by motor abilities. PLoS One. 2025 Jan 7;20(1):e0312875. doi: 10.1371/journal.pone.0312875. PMID: 39775188; PMCID: PMC11706474.
  2. Hemmingsen D, Moster D, Engdahl BL, Klingenberg C. Sensorineural hearing impairment among preterm children: a Norwegian population-based study. Arch Dis Child Fetal Neonatal Ed. 2024 Dec 20;110(1):68-74. doi: 10.1136/archdischild-2024-326870. PMID: 38839263.
  3. Peterson BS, Delavari S, Sadik J, Ersland L, Elgen IB, Sawardekar S, Bansal R, Aukland SM. Brain tissue microstructure in a prospective, longitudinal, population-based cohort of preterm and term-born young adults. J Child Psychol Psychiatry. 2024 Nov 19. doi: 10.1111/jcpp.14069. Epub ahead of print. PMID: 39561978.
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  44. Markestad T, Kaaresen PI, Rønnestad A, Reigstad H, Lossius K, Medbø S, Zanussi G, Engelund IE, Skjaerven R, Irgens LM; Norwegian Extreme Prematurity Study Group. Early death, morbidity, and need of treatment among extremely premature infants. Pediatrics. 2005 May;115(5):1289-98. doi: 10.1542/peds.2004-1482. PMID: 15867037.
  45. Høie B, Mykletun A, Sommerfelt K, Bjørnaes H, Skeidsvoll H, Waaler PE. Seizure-related factors and non-verbal intelligence in children with epilepsy. A population-based study from Western Norway. Seizure. 2005 Jun;14(4):223-31. doi: 10.1016/j.seizure.2004.10.006. PMID: 15893478.
  46. Waaler PE, Sommerfelt K. Barnenevrologi og habilitering i Norge [Paediatric neurology and habilitation in Norway]. Tidsskr Nor Laegeforen. 2004 Oct 7;124(19):2486-7. Norwegian. PMID: 15477886.
  47. Elgen I, Lundervold AJ, Sommerfelt K. Aspects of inattention in low birth weight children. Pediatr Neurol. 2004 Feb;30(2):92-8. doi: 10.1016/S0887-8994(03)00402-8. PMID: 14984899.
  48. Elgen I, Sommerfelt K, Ellertsen B. Cognitive performance in a low birth weight cohort at 5 and 11 years of age. Pediatr Neurol. 2003 Aug;29(2):111-6. doi: 10.1016/s0887-8994(03)00211-x. PMID: 14580653.
  49. Elgen I, Sommerfelt K, Markestad T. Population based, controlled study of behavioural problems and psychiatric disorders in low birthweight children at 11 years of age. Arch Dis Child Fetal Neonatal Ed. 2002 Sep;87(2):F128-32. doi: 10.1136/fn.87.2.f128. PMID: 12193521; PMCID: PMC1721443.
  50. Elgen I, Sommerfelt K. Low birthweight children: coping in school? Acta Paediatr. 2002;91(8):939-45. doi: 10.1080/080352502760148676. PMID: 12222719.
  51. Sommerfelt K, Sonnander K, Skranes J, Andersson HW, Ahlsten G, Ellertsen B, Markestad T, Jacobsen G, Hoffman HJ, Bakketeig LS. Neuropsychologic and motor function in small-for-gestation preschoolers. Pediatr Neurol. 2002 Mar;26(3):186-91. doi: 10.1016/s0887-8994(01)00381-2. PMID: 11955924.
  52. Moster D, Lie RT, Markestad T. Joint association of Apgar scores and early neonatal symptoms with minor disabilities at school age. Arch Dis Child Fetal Neonatal Ed. 2002 Jan;86(1):F16-21. doi: 10.1136/fn.86.1.f16. PMID: 11815542; PMCID: PMC1721350.
  53. Sommerfelt K, Andersson HW, Sonnander K, Ahlsten G, Ellertsen B, Markestad T, Jacobsen G, Bakketeig LS. Behavior in term, small for gestational age preschoolers. Early Hum Dev. 2001 Dec;65(2):107-21. doi: 10.1016/s0378-3782(01)00200-6. PMID: 11641032.
  54. Andersson HW, Sommerfelt K. The relationship between cognitive abilities and maternal ratings of externalizing behaviors in preschool children. Scand J Psychol. 2001 Dec;42(5):437-44. doi: 10.1111/1467-9450.00256. PMID: 11771813.
  55. Sommerfelt K, Markestad T, Berg K, Saetesdal I. Therapeutic electrical stimulation in cerebral palsy: a randomized, controlled, crossover trial. Dev Med Child Neurol. 2001 Sep;43(9):609-13. doi: 10.1017/s0012162201001104. PMID: 11570629.
  56. Moster D, Lie RT, Irgens LM, Bjerkedal T, Markestad T. The association of Apgar score with subsequent death and cerebral palsy: A population-based study in term infants. J Pediatr. 2001 Jun;138(6):798-803. doi: 10.1067/mpd.2001.114694. PMID: 11391319.
  57. Sommerfelt K. Cerebral parese--forekomst og tolking [Cerebral paresis--occurrence and diagnosis]. Tidsskr Nor Laegeforen. 2001 Oct 20;121(25):2916. Norwegian. PMID: 11715772.
  58. Reigstad H, Markestad T. Behandling av ekstremt premature born--kva grenser og kva problem? [Treatment of extremely premature infants--which limits and what problems?]. Tidsskr Nor Laegeforen. 2001 Feb 28;121(6):711-4. Norwegian. PMID: 11293356.
  59. Pedersen SJ, Sommerfelt K, Markestad T. Early motor development of premature infants with birthweight less than 2000 grams. Acta Paediatr. 2000 Dec;89(12):1456-61. doi: 10.1080/080352500456642. PMID: 11195236.
  60. Olafsdottir E, Forshei S, Fluge G, Markestad T. Randomised controlled trial of infantile colic treated with chiropractic spinal manipulation. Arch Dis Child. 2001 Feb;84(2):138-41. doi: 10.1136/adc.84.2.138. PMID: 11159288; PMCID: PMC1718650.
  61. Sommerfelt K, Andersson HW, Sonnander K, Ahlsten G, Ellertsen B, Markestad T, Jacobsen G, Hoffman HJ, Bakketeig L. Cognitive development of term small for gestational age children at five years of age. Arch Dis Child. 2000 Jul;83(1):25-30. doi: 10.1136/adc.83.1.25. PMID: 10868995; PMCID: PMC1718382.
  62. Olafsen KS, Sommerfelt K. The Yale Children's Inventory--a screening tool for attention deficits and related disorders. Normative data for boys. Scand J Psychol. 1999 Jun;40(2):121-5. doi: 10.1111/1467-9450.00108. PMID: 10399494.
  63. Andersson HW, Sonnander K, Sommerfelt K. Gender and its contribution to the prediction of cognitive abilities at 5 years. Scand J Psychol. 1998 Dec;39(4):267-74. doi: 10.1111/1467-9450.00086. PMID: 9883102.
  64. Markestad T. Unge uføre [Young disabled]. Tidsskr Nor Laegeforen. 1998 Jun 10;118(15):2304. Norwegian. PMID: 9691794.
  65. Sommerfelt K, Markestad T, Ellertsen B. Neuropsychological performance in low birth weight preschoolers: a population-based, controlled study. Eur J Pediatr. 1998 Jan;157(1):53-8. doi: 10.1007/s004310050766. PMID: 9461364.
  66. Sommerfelt K. Long-term outcome for non-handicapped low birth weight infants--is the fog clearing? Eur J Pediatr. 1998 Jan;157(1):1-3. doi: 10.1007/s004310050755. PMID: 9461353.
  67. Vik T, Vatten L, Markestad T, Jacobsen G, Bakketeig LS. Dubowitz assessment of gestational age and agreement with prenatal methods. Am J Perinatol. 1997 Jul;14(6):369-73. doi: 10.1055/s-2007-994163. PMID: 9217961.
  68. Haugen OH, Markestad T. Incidence of retinopathy of prematurity (ROP) in the western part of Norway. A population-based retrospective study. Acta Ophthalmol Scand. 1997 Jun;75(3):305-7. doi: 10.1111/j.1600-0420.1997.tb00780.x. PMID: 9253981.
  69. Markestad T. Use of sucrose as a treatment for infant colic. Arch Dis Child. 1997 Apr;76(4):356-7; discussion 357-8. doi: 10.1136/adc.76.4.356. PMID: 9166032; PMCID: PMC1717160.
  70. Skadberg BT, Markestad T. Behaviour and physiological responses during prone and supine sleep in early infancy. Arch Dis Child. 1997 Apr;76(4):320-4. doi: 10.1136/adc.76.4.320. PMID: 9166023; PMCID: PMC1717149.
  71. Sommerfelt K, Pedersen S, Ellertsen B, Markestad T. Transient dystonia in non-handicapped low-birthweight infants and later neurodevelopment. Acta Paediatr. 1996 Dec;85(12):1445-9. doi: 10.1111/j.1651-2227.1996.tb13950.x. PMID: 9001656.
  72. Skadberg BT, Markestad T. Infant behaviour in response to a change in body position from side to prone during sleep. Eur J Pediatr. 1996 Dec;155(12):1052-6. doi: 10.1007/BF02532530. PMID: 8956944.
  73. Sommerfelt K, Troland K, Ellertsen B, Markestad T. Behavioral problems in low-birthweight preschoolers. Dev Med Child Neurol. 1996 Oct;38(10):927-40. doi: 10.1111/j.1469-8749.1996.tb15049.x. PMID: 8870614.
  74. Andersson HW, Sommerfelt K, Sonnander K, Ahlsten G. Maternal child-rearing attitudes, IQ, and socioeconomic status as related to cognitive abilities of five-year-old children. Psychol Rep. 1996 Aug;79(1):3-14. doi: 10.2466/pr0.1996.79.1.3. PMID: 8873781.
  75. Vik T, Vatten L, Markestad T, Ahlsten G, Jacobsen G, Bakketeig LS. Morbidity during the first year of life in small for gestational age infants. Arch Dis Child Fetal Neonatal Ed. 1996 Jul;75(1):F33-7. doi: 10.1136/fn.75.1.f33. PMID: 8795353; PMCID: PMC1061147.
  76. Sommerfelt K, Ellertsen B, Markestad T. Low birthweight and neuromotor development: a population based, controlled study. Acta Paediatr. 1996 May;85(5):604-10. doi: 10.1111/j.1651-2227.1996.tb14096.x. PMID: 8827107.
  77. Markestad T, Irgens LM. Mageleie og krybbedød [Prone position and crib death]. Tidsskr Nor Laegeforen. 1995 Nov 20;115(28):3480-1. Norwegian. PMID: 7491596.
  78. Sommerfelt K, Ellertsen B, Markestad T. Parental factors in cognitive outcome of non-handicapped low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 1995 Nov;73(3):F135-42. doi: 10.1136/fn.73.3.f135. PMID: 8535868; PMCID: PMC2528464.
  79. Skadberg BT, Oterhals A, Finborud K, Markestad T. CO2 rebreathing: a possible contributory factor to some cases of sudden infant death? Acta Paediatr. 1995 Sep;84(9):988-95. doi: 10.1111/j.1651-2227.1995.tb13813.x. PMID: 8652973.
  80. Irgens LM, Markestad T, Baste V, Schreuder P, Skjaerven R, Øyen N. Sleeping position and sudden infant death syndrome in Norway 1967-91. Arch Dis Child. 1995 Jun;72(6):478-82. doi: 10.1136/adc.72.6.478. PMID: 7618929; PMCID: PMC1511132.
  81. Markestad T, Skadberg B, Hordvik E, Morild I, Irgens LM. Sleeping position and sudden infant death syndrome (SIDS): effect of an intervention programme to avoid prone sleeping. Acta Paediatr. 1995 Apr;84(4):375-8. doi: 10.1111/j.1651-2227.1995.tb13653.x. PMID: 7795344.
  82. Sommerfelt K, Markestad T. Fødselen og barnets hjerne [Delivery and the infant's brain]. Tidsskr Nor Laegeforen. 1994 Jan 10;114(1):15-6. Norwegian. PMID: 8296274.
  83. Sommerfelt K, Ellertsen B, Markestad T. Personality and behaviour in eight-year-old, non-handicapped children with birth weight under 1500 g. Acta Paediatr. 1993 Sep;82(9):723-8. doi: 10.1111/j.1651-2227.1993.tb12546.x. PMID: 8241666.
  84. Köhler L, Markestad T. Consensus statement on prevention program for SIDS. Acta Paediatr Suppl. 1993 Jun;82 Suppl 389:126-7. doi: 10.1111/j.1651-2227.1993.tb12899.x. PMID: 8374181.
  85. Markestad T. Information about sudden infant death syndrome for the general public. Acta Paediatr Suppl. 1993 Jun;82 Suppl 389:124-5. doi: 10.1111/j.1651-2227.1993.tb12898.x. PMID: 8374180.
  86. Markestad T. Smerter hos spedbarn [Pain in infants]. Tidsskr Nor Laegeforen. 1992 Nov 10;112(27):3421. Norwegian. PMID: 1462305.
  87. Markestad T. Sovestilling og krybbedød i Norge [Sleeping position and crib death in Norway]. Tidsskr Nor Laegeforen. 1992 Apr 30;112(11):1427-9. Norwegian. PMID: 1631812.
  88. Kyllerman M, Sommerfelt K, Hedström A, Wennergren G, Holmgren D. Clinical and neurophysiological development of Unverricht-Lundborg disease in four Swedish siblings. Epilepsia. 1991 Nov-Dec;32(6):900-9. doi: 10.1111/j.1528-1157.1991.tb05549.x. PMID: 1743164.
  89. Haugen OH, Seland JH, Sommerfelt K, Waaler PE. Diagnostikk av Spielmeyer-Vogts sykdom. Elektronmikroskopi av konjunktivalbiopsi [Diagnosis of Spielmayer-Vogt disease. Electron microscopy of conjunctival biopsy]. Tidsskr Nor Laegeforen. 1991 Aug 10;111(18):2265-6. Norwegian. PMID: 1896981.
  90. Sommerfelt K, Kyllerman M, Sanner G. Hereditary spastic paraplegia with epileptic myoclonus. Acta Neurol Scand. 1991 Aug;84(2):157-60. doi: 10.1111/j.1600-0404.1991.tb04925.x. PMID: 1950452.
  91. Waaler PE, Pedersen SJ, Sommerfelt K. Barneneurologi ved regionsykehus [Child neurology in a regional hospital]. Tidsskr Nor Laegeforen. 1991 Apr 20;111(10):1226-9. Norwegian. PMID: 2042129.
  92. Sommerfelt K, Vogt H. Aksidentell forgiftning hos barn [Accidental poisoning in children]. Tidsskr Nor Laegeforen. 1990 Aug 10;110(18):2345-8. Norwegian. PMID: 2218987.
  93. Finne PH, Markestad T, Hauge H. Cerebral parese i Hordaland 1974-83 [Cerebral palsy in Hordaland 1974-1983]. Tidsskr Nor Laegeforen. 1988 May 10;108(13):1001-4. Norwegian. PMID: 3388317.
Inborn errors of metabolism

Lysosomal storage disease e.g. Fabry disease and mithochondial disease e.g. POLG disease are seldom, but put together as orphan diseases affect relatively many patients in pediatric care. The diagnostics and care of these diseases have special challenges due to the relatively low number of patients with each specific disease.

 

PhD dissertations:

 

Peer review publications:

  1. Neugebauer J, Reinson K, Bellusci M, Park JH, Hikmat O, Bertini E, Schiff M; MetabERN PM‐MD Consortium authors; Rahman S. Current global vitamin and cofactor prescribing practices for primary mitochondrial diseases: Results of a European reference network survey. J Inherit Metab Dis. 2025 Jan;48(1):e12805. doi: 10.1002/jimd.12805. Epub 2024 Nov 11. PMID: 39529390; PMCID: PMC11670042.
  2. Eng HM, Sveen KA, Fagerås SJ, Strøm MS, Diep LM, Juliusson PB, Alfsen GC. Introduction of electronic death notification in Norway-Impact on diabetes mortality registration. PLoS One. 2024 Dec 2;19(12):e0311106. doi: 10.1371/journal.pone.0311106. PMID: 39621642; PMCID: PMC11611212.
  3. Jacobsen KK, Laborie LB, Kristiansen H, Schäfer A, Gundersen T, Zayats T, Rosendahl K. Genetics of hip dysplasia - a systematic literature review. BMC Musculoskelet Disord. 2024 Oct 1;25(1):762. doi: 10.1186/s12891-024-07795-2. PMID: 39354451; PMCID: PMC11445845.
  4. Kristensen E, Mathisen L, Berland S, Klingenberg C, Brodtkorb E, Rasmussen M, Tangeraas T, Bliksrud YT, Rahman S, Bindoff LA, Hikmat O. Epidemiology and natural history of POLG disease in Norway: a nationwide cohort study. Ann Clin Transl Neurol.2024 Jul;11(7):1819-1830. doi: 10.1002/acn3.52088. Epub 2024 Jun 7. PMID: 38845467; PMCID: PMC11251482.
  5. Jacobsen KK, Børte S, Laborie LB, Kristiansen H, Schäfer A; HUNT All-In Pain; Gundersen T, Zayats T, Slagsvold Winsvold BK, Rosendahl K. COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study. Osteoarthr Cartil Open. 2023 Dec 16;6(1):100424. doi: 10.1016/j.ocarto.2023.100424. PMID: 38283578; PMCID: PMC10820335.
  6. Bichet DG, Hopkin RJ, Aguiar P, Allam SR, Chien YH, Giugliani R, Kallish S, Kineen S, Lidove O, Niu DM, Olivotto I, Politei J, Rakoski P, Torra R, Tøndel C, Hughes DA. Consensus recommendations for the treatment and management of patients with Fabry disease on migalastat: a modified Delphi study. Front Med (Lausanne). 2023 Sep 1;10:1220637. doi: 10.3389/fmed.2023.1220637. PMID: 37727761; PMCID: PMC10505750.
  7. Burlina A, Brand E, Hughes D, Kantola I, Krӓmer J, Nowak A, Tøndel C, Wanner C, Spada M. An expert consensus on the recommendations for the use of biomarkers in Fabry disease. Mol Genet Metab. 2023 Jun;139(2):107585. doi: 10.1016/j.ymgme.2023.107585. Epub 2023 Apr 17. PMID: 37207471.
  8. Hopkin RJ, Cabrera GH, Jefferies JL, Yang M, Ponce E, Brand E, Feldt-Rasmussen U, Germain DP, Guffon N, Jovanovic A, Kantola I, Karaa A, Martins AM, Tøndel C, Wilcox WR, Yoo HW, Burlina AP, Mauer M. Clinical outcomes among young patients with Fabry disease who initiated agalsidase beta treatment before 30 years of age: An analysis from the Fabry Registry. Mol Genet Metab. 2023 Feb;138(2):106967. doi: 10.1016/j.ymgme.2022.106967. Epub 2022 Nov 30. PMID: 36709533.
  9. Björkman K, Vissing J, Østergaard E, Bindoff LA, de Coo IFM, Engvall M, Hikmat O, Isohanni P, Kollberg G, Lindberg C, Majamaa K, Naess K, Uusimaa J, Tulinius M, Darin N. Phenotypic spectrum and clinical course of single large-scale mitochondrial DNA deletion disease in the paediatric population: a multicentre study. J Med Genet. 2023 Jan;60(1):65-73. doi: 10.1136/jmedgenet-2021-108006. Epub 2021 Dec 6. PMID: 34872991; PMCID: PMC9811091.
  10. Berland S, Rustad CF, Bentsen MHL, Wollen EJ, Turowski G, Johansson S, Houge G, Haukanes BI. Double paternal uniparental isodisomy 7 and 15 presenting with Beckwith-Wiedemann spectrum features. Cold Spring Harb Mol Case Stud. 2021 Dec 9;7(6):a006113. doi: 10.1101/mcs.a006113. PMID: 34615670; PMCID: PMC8751407.
  11. Varhaug KN, Hikmat O, Bindoff LA. Mitokondriesykdom forårsaket av m.3243A>G-mutasjonen [Mitochondrial disease caused by the m.3243A>G mutation]. Tidsskr Nor Laegeforen. 2022 Jun 27;142(10). Norwegian. doi: 10.4045/tidsskr.21.0729. PMID: 35763848.
  12. Parasyri M, Brandström P, Uusimaa J, Ostergaard E, Hikmat O, Isohanni P, Naess K, de Coo IFM, Nascimento Osorio A, Nuutinen M, Lindberg C, Bindoff LA, Tulinius M, Darin N, Sofou K. Renal Phenotype in Mitochondrial Diseases: A Multicenter Study. Kidney Dis (Basel). 2022 Jan 24;8(2):148-159. doi: 10.1159/000521148. PMID: 35527992; PMCID: PMC9021658.
  13. Hikmat O, Isohanni P, Keshavan N, Ferla MP, Fassone E, Abbott MA, Bellusci M, Darin N, Dimmock D, Ghezzi D, Houlden H, Invernizzi F, Kamarus Jaman NB, Kurian MA, Morava E, Naess K, Ortigoza-Escobar JD, Parikh S, Pennisi A, Barcia G, Tylleskär KB, Brackman D, Wortmann SB, Taylor JC, Bindoff LA, Fellman V, Rahman S. Expanding the phenotypic spectrum of BCS1L-related mitochondrial disease. Ann Clin Transl Neurol. 2021 Nov;8(11):2155-2165. doi: 10.1002/acn3.51470. Epub 2021 Oct 18. PMID: 34662929; PMCID: PMC8607453.
  14. Varhaug KN, Hikmat O, Nakkestad HL, Vedeler CA, Bindoff LA. Serum biomarkers in primary mitochondrial disorders. Brain Commun. 2021 Jan 4;3(1):fcaa222. doi: 10.1093/braincomms/fcaa222. PMID: 33501425; PMCID: PMC7811758.
  15. Hikmat O, Naess K, Engvall M, Klingenberg C, Rasmussen M, Tallaksen CME, Samsonsen C, Brodtkorb E, Ostergaard E, de Coo R, Pias-Peleteiro L, Isohanni P, Uusimaa J, Darin N, Rahman S, Bindoff LA. The impact of gender, puberty, and pregnancy in patients with POLG disease. Ann Clin Transl Neurol. 2020 Oct;7(10):2019-2025. doi: 10.1002/acn3.51199. Epub 2020 Sep 18. PMID: 32949115; PMCID: PMC7545595.
  16. Lehtonen JM, Auranen M, Darin N, Sofou K, Bindoff L, Hikmat O, Uusimaa J, Vieira P, Tulinius M, Lönnqvist T, de Coo IF, Suomalainen A, Isohanni P. Diagnostic value of serum biomarkers FGF21 and GDF15 compared to muscle sample in mitochondrial disease. J Inherit Metab Dis. 2021 Mar;44(2):469-480. doi: 10.1002/jimd.12307. Epub 2020 Sep 21. PMID: 32857451.
  17. Hikmat O, Naess K, Engvall M, Klingenberg C, Rasmussen M, Tallaksen CM, Brodtkorb E, Ostergaard E, de Coo IFM, Pias-Peleteiro L, Isohanni P, Uusimaa J, Darin N, Rahman S, Bindoff LA. Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases. J Inherit Metab Dis. 2020 Jul;43(4):726-736. doi: 10.1002/jimd.12211. Epub 2020 Jan 23. PMID: 32391929.
  18. Berland S, Haukanes BI, Juliusson PB, Houge G. Deep exploration of a CDKN1C mutation causing a mixture of Beckwith-Wiedemann and IMAGe syndromes revealed a novel transcript associated with developmental delay. J Med Genet. 2022 Feb;59(2):155-164. doi: 10.1136/jmedgenet-2020-107401. Epub 2020 Dec 21. PMID: 33443097; PMCID: PMC8788247.
  19. Hikmat O, Varhaug KN, Bindoff LA. Polymerase gamma-relatert mitokondriesykdom [Polymerase gamma-related mitochondrial disorder]. Tidsskr Nor Laegeforen. 2020 Jan 13;140(1). Norwegian. doi: 10.4045/tidsskr.19.0368. PMID: 31948198.
  20. Bownass L, Abbs S, Armstrong R, Baujat G, Behzadi G, Berentsen RD, Burren C, Calder A, Cormier-Daire V, Newbury-Ecob R, Foulds N, Juliusson PB, Kant SG, Lefroy H, Mehta SG, Merckoll E, Michot C, Monsell F, Offiah AC, Richards A, Rosendahl K, Rustad CF, Shears D, Tveten K, Wellesley D, Wordsworth P; Deciphering Developmental Disorders Study; Smithson S. PAPSS2-related brachyolmia: Clinical and radiological phenotype in 18 new cases. Am J Med Genet A. 2019 Sep;179(9):1884-1894. doi: 10.1002/ajmg.a.61282. Epub 2019 Jul 16. PMID: 31313512.
  21. Drage Berentsen R, Haukanes BI, Júlíusson PB, Rosendahl K, Houge G. A Novel GDF6 Mutation in a Family with Multiple Synostoses Syndrome without Hearing Loss. Mol Syndromol. 2019 Jan;9(5):228-234. doi: 10.1159/000492418. Epub 2018 Aug 15. PMID: 30733656; PMCID: PMC6362854.
  22. Wanner C, Arad M, Baron R, Burlina A, Elliott PM, Feldt-Rasmussen U, Fomin VV, Germain DP, Hughes DA, Jovanovic A, Kantola I, Linhart A, Mignani R, Monserrat L, Namdar M, Nowak A, Oliveira JP, Ortiz A, Pieroni M, Spada M, Tylki-Szymańska A, Tøndel C, Viana-Baptista M, Weidemann F, Hilz MJ. European expert consensus statement on therapeutic goals in Fabry disease. Mol Genet Metab. 2018 Jul;124(3):189-203. doi: 10.1016/j.ymgme.2018.06.004. Epub 2018 Jun 12. PMID: 30017653.
  23. Spada M, Baron R, Elliott PM, Falissard B, Hilz MJ, Monserrat L, Tøndel C, Tylki-Szymańska A, Wanner C, Germain DP. The effect of enzyme replacement therapy on clinical outcomes in paediatric patients with Fabry disease - A systematic literature review by a European panel of experts. Mol Genet Metab. 2019 Mar;126(3):212-223. doi: 10.1016/j.ymgme.2018.04.007. Epub 2018 Apr 26. PMID: 29785937.
  24. Bowman P, Sulen Å, Barbetti F, Beltrand J, Svalastoga P, Codner E, Tessmann EH, Juliusson PB, Skrivarhaug T, Pearson ER, Flanagan SE, Babiker T, Thomas NJ, Shepherd MH, Ellard S, Klimes I, Szopa M, Polak M, Iafusco D, Hattersley AT, Njølstad PR; Neonatal Diabetes International Collaborative Group. Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study. Lancet Diabetes Endocrinol. 2018 Aug;6(8):637-646. doi: 10.1016/S2213-8587(18)30106-2. Epub 2018 Jun 4. Erratum in: Lancet Diabetes Endocrinol. 2018 Sep;6(9):e17. PMID: 29880308; PMCID: PMC6058077.
  25. Maas RR, Iwanicka-Pronicka K, Kalkan Ucar S, Alhaddad B, AlSayed M, Al-Owain MA, Al-Zaidan HI, Balasubramaniam S, Barić I, Bubshait DK, Burlina A, Christodoulou J, Chung WK, Colombo R, Darin N, Freisinger P, Garcia Silva MT, Grunewald S, Haack TB, van Hasselt PM, Hikmat O, Hörster F, Isohanni P, Ramzan K, Kovacs-Nagy R, Krumina Z, Martin-Hernandez E, Mayr JA, McClean P, De Meirleir L, Naess K, Ngu LH, Pajdowska M, Rahman S, Riordan G, Riley L, Roeben B, Rutsch F, Santer R, Schiff M, Seders M, Sequeira S, Sperl W, Staufner C, Synofzik M, Taylor RW, Trubicka J, Tsiakas K, Unal O, Wassmer E, Wedatilake Y, Wolff T, Prokisch H, Morava E, Pronicka E, Wevers RA, de Brouwer AP, Wortmann SB. Progressive deafness-dystonia due to SERAC1 mutations: A study of 67 cases. Ann Neurol. 2017 Dec;82(6):1004-1015. doi: 10.1002/ana.25110. PMID: 29205472; PMCID: PMC5847115.
  26. Hikmat O, Tzoulis C, Klingenberg C, Rasmussen M, Tallaksen CME, Brodtkorb E, Fiskerstrand T, McFarland R, Rahman S, Bindoff LA. The presence of anaemia negatively influences survival in patients with POLG disease. J Inherit Metab Dis. 2017 Nov;40(6):861-866. doi: 10.1007/s10545-017-0084-9. Epub 2017 Sep 1. Erratum in: J Inherit Metab Dis. 2017 Sep 26;: PMID: 28865037.
  27. Bjellmo S, Andersen GL, Martinussen MP, Romundstad PR, Hjelle S, Moster D, Vik T. Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway. BMJ Open. 2017 May 4;7(4):e014979. doi: 10.1136/bmjopen-2016-014979. PMID: 28473516; PMCID: PMC5566597.
  28. Hikmat O, Tzoulis C, Chong WK, Chentouf L, Klingenberg C, Fratter C, Carr LJ, Prabhakar P, Kumaraguru N, Gissen P, Cross JH, Jacques TS, Taanman JW, Bindoff LA, Rahman S. The clinical spectrum and natural history of early-onset diseases due to DNA polymerase gamma mutations. Genet Med. 2017 Nov;19(11):1217-1225. doi: 10.1038/gim.2017.35. Epub 2017 Apr 27. Erratum in: Genet Med. 2019 Apr;21(4):1027. PMID: 28471437.
  29. Suntjens E, Dreschler WA, Hess-Erga J, Skrunes R, Wijburg FA, Linthorst GE, Tøndel C, Biegstraaten M. Hearing loss in children with Fabry disease. J Inherit Metab Dis. 2017 Sep;40(5):725-731. doi: 10.1007/s10545-017-0051-5. Epub 2017 May 31. PMID: 28567540; PMCID: PMC5579138.
  30. Johansson BB, Irgens HU, Molnes J, Sztromwasser P, Aukrust I, Juliusson PB, Søvik O, Levy S, Skrivarhaug T, Joner G, Molven A, Johansson S, Njølstad PR. Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry. Diabetologia. 2017 Apr;60(4):625-635. doi: 10.1007/s00125-016-4167-1. Epub 2016 Dec 2. PMID: 27913849.
  31. Rafaelsen S, Johansson S, Ræder H, Bjerknes R. Hereditary hypophosphatemia in Norway: a retrospective population-based study of genotypes, phenotypes, and treatment complications. Eur J Endocrinol. 2016 Feb;174(2):125-36. doi: 10.1530/EJE-15-0515. Epub 2015 Nov 5. PMID: 26543054; PMCID: PMC4674593.
  32. Rosendahl K, Houge G, Gradek GA, Berland S, Fevang JM, Berentsen RD, Júlíusson PB. Spesialpoliklinikk for skjelettdysplasier [Special outpatient clinic for skeletal dysplasias]. Tidsskr Nor Laegeforen. 2015 Mar 10;135(5):419-20. Norwegian. doi: 10.4045/tidsskr.14.1022. PMID: 25761024.
  33. Biegstraaten M, Arngrímsson R, Barbey F, Boks L, Cecchi F, Deegan PB, Feldt-Rasmussen U, Geberhiwot T, Germain DP, Hendriksz C, Hughes DA, Kantola I, Karabul N, Lavery C, Linthorst GE, Mehta A, van de Mheen E, Oliveira JP, Parini R, Ramaswami U, Rudnicki M, Serra A, Sommer C, Sunder-Plassmann G, Svarstad E, Sweeb A, Terryn W, Tylki-Szymanska A, Tøndel C, Vujkovac B, Weidemann F, Wijburg FA, Woolfson P, Hollak CE. Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document. Orphanet J Rare Dis. 2015 Mar 27;10:36. doi: 10.1186/s13023-015-0253-6. PMID: 25885911; PMCID: PMC4383065.
  34. Rafaelsen S, Johansson S, Ræder H, Bjerknes R. Long-term clinical outcome and phenotypic variability in hyperphosphatemic familial tumoral calcinosis and hyperphosphatemic hyperostosis syndrome caused by a novel GALNT3 mutation; case report and review of the literature. BMC Genet. 2014 Sep 24;15:98. doi: 10.1186/s12863-014-0098-3. PMID: 25249269; PMCID: PMC4181413.
  35. van der Tol L, Cassiman D, Houge G, Janssen MC, Lachmann RH, Linthorst GE, Ramaswami U, Sommer C, Tøndel C, West ML, Weidemann F, Wijburg FA, Svarstad E, Hollak CE, Biegstraaten M. Uncertain diagnosis of fabry disease in patients with neuropathic pain, angiokeratoma or cornea verticillata: consensus on the approach to diagnosis and follow-up. JIMD Rep. 2014;17:83-90. doi: 10.1007/8904_2014_342. Epub 2014 Sep 16. PMID: 25224312; PMCID: PMC4241201.
  36. Frøisland DH, Graue M, Markestad T, Skrivarhaug T, Wentzel-Larsen T, Dahl-Jørgensen K. Health-related quality of life among Norwegian children and adolescents with type 1 diabetes on intensive insulin treatment: a population-based study. Acta Paediatr. 2013 Sep;102(9):889-95. doi: 10.1111/apa.12312. Epub 2013 Jul 16. PMID: 23738648.
  37. Laborie LB, Markestad TJ, Davidsen H, Brurås KR, Aukland SM, Bjørlykke JA, Reigstad H, Indrekvam K, Lehmann TG, Engesæter IØ, Engesæter LB, Rosendahl K. Selective ultrasound screening for developmental hip dysplasia: effect on management and late detected cases. A prospective survey during 1991-2006. Pediatr Radiol. 2014 Apr;44(4):410-24. doi: 10.1007/s00247-013-2838-3. Epub 2013 Dec 13. PMID: 24337789.
  38. Mjelle AB, Júlíusson PB, Aukland SM. Barn med krumme legger [Child with crooked legs]. Tidsskr Nor Laegeforen. 2014 Feb 25;134(4):422. Norwegian. doi: 10.4045/tidsskr.13.1183. PMID: 24569742.
  39. Linthorst GE, Burlina AP, Cecchi F, Cox TM, Fletcher JM, Feldt-Rasmussen U, Giugliani R, Hollak CE, Houge G, Hughes D, Kantola I, Lachmann R, Lopez M, Ortiz A, Parini R, Rivera A, Rolfs A, Ramaswami U, Svarstad E, Tøndel C, Tylki-Szymanska A, Vujkovac B, Waldek S, West M, Weidemann F, Mehta A. Recommendations on reintroduction of agalsidase Beta for patients with fabry disease in europe, following a period of shortage. JIMD Rep. 2013;8:51-6. doi: 10.1007/8904_2012_160. Epub 2012 Jul 14. PMID: 23430520; PMCID: PMC3565660.
  40. Rafaelsen SH, Raeder H, Fagerheim AK, Knappskog P, Carpenter TO, Johansson S, Bjerknes R. Exome sequencing reveals FAM20c mutations associated with fibroblast growth factor 23-related hypophosphatemia, dental anomalies, and ectopic calcification. J Bone Miner Res. 2013 Jun;28(6):1378-85. doi: 10.1002/jbmr.1850. PMID: 23325605.
  41. Bertelsen AK, Tøndel C, Krohn J, Bull N, Aarseth J, Houge G, Mellgren SI, Vedeler CA. Small fibre neuropathy in Fabry disease. J Neurol. 2013 Mar;260(3):917-9. doi: 10.1007/s00415-012-6800-3. Epub 2012 Dec 21. PMID: 23263477.
  42. Frøisland DH, Markestad T, Wentzel-Larsen T, Skrivarhaug T, Dahl-Jørgensen K, Graue M. Reliability and validity of the Norwegian child and parent versions of the DISABKIDS Chronic Generic Module (DCGM-37) and Diabetes-Specific Module (DSM-10). Health Qual Life Outcomes. 2012 Feb 2;10:19. doi: 10.1186/1477-7525-10-19. PMID: 22300248; PMCID: PMC3296581.
  43. Brodwall KM, Júlíusson PB, Bjerknes R, Hovland R, Fiskerstrand T. Trikorhinofalangealt syndrom--klinisk presentasjon og genetikk [Trichorhinophalangeal syndrome--clinical presentation and genetics]. Tidsskr Nor Laegeforen. 2011 Aug 9;131(15):1420-3. Norwegian. doi: 10.4045/tidsskr.09.0551. PMID: 21844942.
  44. Houge G, Tøndel C, Kaarbøe O, Hirth A, Bostad L, Svarstad E. Fabry or not Fabry--a question of ascertainment. Eur J Hum Genet. 2011 Nov;19(11):1111. doi: 10.1038/ejhg.2011.87. Epub 2011 May 18. PMID: 21587323; PMCID: PMC3198147.
  45. Markestad T. Opplysninger om arvelig disposisjon ved søknad om helseforsikring [Information about hereditary disposition in connection with health insurance application]. Tidsskr Nor Laegeforen. 2011 May 20;131(9-10):975-7. Norwegian. doi: 10.4045/tidsskr.11.0531. PMID: 21607001.
  46. Brurås KR, Aukland SM, Markestad T, Sera F, Dezateux C, Rosendahl K. Newborns with sonographically dysplastic and potentially unstable hips: 6-year follow-up of an RCT. Pediatrics. 2011 Mar;127(3):e661-6. doi: 10.1542/peds.2010-2572. Epub 2011 Feb 14. PMID: 21321039.
  47. Guest JF, Jenssen T, Houge G, Aaseboe W, Tøndel C, Svarstad E. Modelling the resource implications of managing adults with Fabry disease in Norway favours home infusion. Eur J Clin Invest. 2010 Dec;40(12):1104-12. doi: 10.1111/j.1365-2362.2010.02363.x. Epub 2010 Sep 9. PMID: 21070219.
  48. Markestad T, Hytten K. Hvor går grensen for reservasjonsretten? [Where is the limit of the right of reservation?]. Tidsskr Nor Laegeforen. 2010 Sep 23;130(18):1844-5. Norwegian. doi: 10.4045/tidsskr.10.0467. PMID: 20882087.
  49. Rosendahl K, Dezateux C, Fosse KR, Aase H, Aukland SM, Reigstad H, Alsaker T, Moster D, Lie RT, Markestad T. Immediate treatment versus sonographic surveillance for mild hip dysplasia in newborns. Pediatrics. 2010 Jan;125(1):e9-16. doi: 10.1542/peds.2009-0357. Epub 2009 Dec 21. PMID: 20026501.
  50. Lacbawan F, Solomon BD, Roessler E, El-Jaick K, Domené S, Vélez JI, Zhou N, Hadley D, Balog JZ, Long R, Fryer A, Smith W, Omar S, McLean SD, Clarkson K, Lichty A, Clegg NJ, Delgado MR, Levey E, Stashinko E, Potocki L, Vanallen MI, Clayton-Smith J, Donnai D, Bianchi DW, Juliusson PB, Njølstad PR, Brunner HG, Carey JC, Hehr U, Müsebeck J, Wieacker PF, Postra A, Hennekam RC, van den Boogaard MJ, van Haeringen A, Paulussen A, Herbergs J, Schrander-Stumpel CT, Janecke AR, Chitayat D, Hahn J, McDonald-McGinn DM, Zackai EH, Dobyns WB, Muenke M. Clinical spectrum of SIX3-associated mutations in holoprosencephaly: correlation between genotype, phenotype and function. J Med Genet. 2009 Jun;46(6):389-98. doi: 10.1136/jmg.2008.063818. Epub 2009 Apr 2. PMID: 19346217; PMCID: PMC3510661.
  51. Aas T, Markestad T. Informasjonen før screening [Information before screening]. Tidsskr Nor Laegeforen. 2007 Oct 18;127(20):2705. Norwegian. PMID: 17972392.
  52. Raeder H, Shaw N, Netelenbos C, Bjerknes R. A case of X-linked hypophosphatemic rickets: complications and the therapeutic use of cinacalcet. Eur J Endocrinol. 2008 Dec;159 Suppl 1:S101-5. doi: 10.1530/EJE-08-0383. Epub 2008 Sep 5. PMID: 18775977.
  53. Downham E, Winterthun S, Nakkestad HL, Hirth A, Halvorsen T, Taylor RW, Bindoff LA. A novel mitochondrial ND5 (MTND5) gene mutation giving isolated exercise intolerance. Neuromuscul Disord. 2008 Apr;18(4):310-4. doi: 10.1016/j.nmd.2008.01.003. PMID: 18396045.
  54. Houge G, Boman H, Lybaek H, Ness GO, Juliusson PB. Lack of meiotic crossovers during oogenesis in an apparent 45,X Ullrich-Turner syndrome patient with three children. Am J Med Genet A. 2006 May 15;140(10):1092-7. doi: 10.1002/ajmg.a.31204. PMID: 16596671.
  55. Tøndel C, Laegreid LM, Hirth A, Houge G, Månsson JE, Søvik O. Intravenøs enzymsubstitusjonsbehandling ved Fabrys sykdom hos barn [Intravenous enzyme substitution therapy in children with Fabry's disease]. Tidsskr Nor Laegeforen. 2003 Dec 4;123(23):3388-90. Norwegian. PMID: 14713976.
  56. Aarskog D, Eiken HG, Bjerknes R, Myking OL. Pituitary dwarfism in the R271W Pit-1 gene mutation. Eur J Pediatr. 1997 Nov;156(11):829-34. doi: 10.1007/s004310050722. PMID: 9392392.
  57. Rosendahl K, Lie RT, Markestad T. Kongenital hofteleddsluksasjon. Ultralydscreening av nyfødte [Congenital hip dislocation. Ultrasonic screening of newborn infants]. Tidsskr Nor Laegeforen. 1997 Jan 30;117(3):346-52. Norwegian. PMID: 9064854.
  58. Rosendahl K, Markestad T, Lie RT. Developmental dysplasia of the hip. A population-based comparison of ultrasound and clinical findings. Acta Paediatr. 1996 Jan;85(1):64-9. doi: 10.1111/j.1651-2227.1996.tb13892.x. PMID: 8834982.
  59. Bjerknes R, Vesterhus P, Aarskog D. Increased neutrophil insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced functional capacity in patients with untreated Laron syndrome. Eur J Endocrinol. 1997 Jan;136(1):92-5. doi: 10.1530/eje.0.1360092. PMID: 9037133.
  60. Rosendahl K, Markestad T, Lie RT, Sudmann E, Geitung JT. Cost-effectiveness of alternative screening strategies for developmental dysplasia of the hip. Arch Pediatr Adolesc Med. 1995 Jun;149(6):643-8. PMID: 7767419.
  61. Rosendahl K, Aslaksen A, Lie RT, Markestad T. Reliability of ultrasound in the early diagnosis of developmental dysplasia of the hip. Pediatr Radiol. 1995;25(3):219-24. doi: 10.1007/BF02021541. PMID: 7644309.
  62. Rosendahl K, Markestad T, Lie RT. Ultrasound screening for developmental dysplasia of the hip in the neonate: the effect on treatment rate and prevalence of late cases. Pediatrics. 1994 Jul;94(1):47-52. PMID: 8008537.
  63. Rosendahl K, Markestad T, Lie RT. Congenital dislocation of the hip: a prospective study comparing ultrasound and clinical examination. Acta Paediatr. 1992 Feb;81(2):177-81. doi: 10.1111/j.1651-2227.1992.tb12198.x. PMID: 1515765.
  64. Rosendahl K, Markestad T, Lie RT. Ultrasound in the early diagnosis of congenital dislocation of the hip: the significance of hip stability versus acetabular morphology. Pediatr Radiol. 1992;22(6):430-3. doi: 10.1007/BF02013504. PMID: 1437367.
  65. Markestad T. Ultralydundersøkelse av hofteledd hos nyfødte [Ultrasonic diagnosis of hip joints in newborn infants]. Tidsskr Nor Laegeforen. 1988 Oct 10;108(28):2349-51. Norwegian. PMID: 3061057.
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Publications

Publications related to various diseases

2013

Ghaderi S, Lie RT, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Erratum to: Cancer in childhood, adolescence, and young adults: a population-based study  of changes in risk of cancer death during four decades in Norway. Cancer Causes Control. 2013 Oct 12. [Epub ahead of print] PubMed PMID: 24122440.

Ghaderi S, Engeland A, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Increased uptake of social security benefits among long-term survivors of cancer  in childhood, adolescence and young adulthood: a Norwegian population-based cohort study. Br J Cancer. 2013 Apr 16;108(7):1525-33.

Ghaderi S, Lie RT, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Cancer in childhood, adolescence, and young adults: a population-based study of changes in  risk of cancer death during four decades in Norway. Cancer Causes Control. 2012 Aug;23(8):1297-305. doi: 10.1007/s10552-012-0007-x. Epub 2012 Jun 17. Erratum in: Cancer Causes Control. 2013 Dec;24(12):2253-6.

Frøisland DH, Graue M, Markestad T, Skrivarhaug T, Wentzel-Larsen T, Dahl-Jørgensen K. Health-related quality of life among Norwegian children and adolescents with type 1 diabetes on intensive insulin treatment: a population-based study. Acta Paediatr. 2013 Sep;102(9):889-95.

 

2012

Frøisland DH, Markestad T, Wentzel-Larsen T, Skrivarhaug T, Dahl-Jørgensen K, Graue M. Reliability and validity of the Norwegian child and parent versions of the DISABKIDS Chronic Generic Module (DCGM-37) and Diabetes-Specific Module (DSM-10). Health Qual Life Outcomes. 2012 Feb 2;10:19. doi: 10.1186/1477-7525-10-19. PubMed PMID: 2230024.

 

2011

Helgeland H, Van Roy B, Sandvik L, Markestad T, Kristensen H. Paediatric functional abdominal pain: significance of child and maternal health. A prospective study. Acta Paediatr. 2011 Nov;100(11):1461-7.

 

2010

Flagstad G, Helgeland H, Markestad T. Faecal calprotectin concentrations in children with functional gastrointestinal disorders diagnosed according to the Pediatric Rome III criteria. Acta Paediatr. 2010 May;99(5):734-7.

 

2009

Frøisland DH, Solevåg AL, Markestad T. [Insulin pump for treatment of children and adolescents with diabetes]. Tidsskr Nor Laegeforen. 2009 May 28;129(11):1094-7.

Helgeland H, Flagstad G, Grøtta J, Vandvik PO, Kristensen H, Markestad T. Diagnosing pediatric functional abdominal pain in children (4-15 years old) according to the Rome III Criteria: results from a Norwegian prospective study. J Pediatr Gastroenterol Nutr. 2009 Sep;49(3):309-15.

Publications related to nutrition and nutritional deficiencies

2014

Bjørke-Monsen AL. Is exclusive breastfeeding ensuring an optimal micronutrient status and psychomotor development in infants? Clin Biochem. 2014 Jun;47(9):714.

Nilsen RM, Mastroiacovo P, Gunnes N, Alsaker ER, Bjørke-Monsen AL, Eussen SJ, Haugen M, Johannessen A, Meltzer HM, Midttun Ø, Stoltenberg C, Ueland PM, Vollset SE. Folic acid supplementation and inter-pregnancy interval. Paediatr Perinat Epidemiol. 2014;28,270-4.

 

2013

Torsvik I, Ueland PM, Markestad T, Bjørke-Monsen AL. Cobalamin supplementation improves motor development and regurgitations in infants: results from a randomized intervention study. Am J Clin Nutr. 2013 Nov;98(5):1233-40.

Torsvik IK, Markestad T, Ueland PM, Nilsen RM, Midttun O, Bjørke Monsen AL. Evaluating iron status and the risk of anemia in young infants using erythrocyte  parameters. Pediatr Res. 2013 Feb;73(2):214-20.

Jenssen HB, Torsvik I, Ueland PM, Midttun Ø, Bjørke-Monsen AL. Biochemical signs of impaired cobalamin function do not affect hematological parameters in young infants: results from a double-blind randomized controlled trial. Pediatr Res. 2013 Sep;74(3):327-32.

Marques A, O'Connor T, Roth C, Susser E, Bjørke-Monsen AL.The influence of maternal prenatal and early childhood nutrition and maternal prenatal stress on offspring immune system development and neurodevelopmental disorders. Frontier of neuroscience; 2013; 120:1-17.

Rot C, Bjørke-Monsen AL, Magnus P, Midttun Ø, Nilsen RM, Reichborn-Kjennerud T, Stoltenberg C, Vollset SE, Ueland PM, Susser E.Use of folic acid supplements in early pregnancy in relation to maternal plasma levels in week 18 of pregnancy. Mol Nutr Food Res. 2013; 57:653-60.

Bjørke Monsen AL, Roth C, Magnus P, Midttun Ø, Nilsen RM, Reichborn-Kjennerud T, Stoltenberg C, Susser E, Vollset SE, Ueland PM. Maternal B vitamin status in pregnancy week 18 according to reported use of folic acid supplements. Mol Nutr Food Res. 2013;57:645-52.

Bjørke Monsen AL, Halvorsen T, Midttun Ø, Ueland PM. Small for gestational age status and inflammatory markers at the age of 10 – 17 years in children born preterm or with an extremely-low-birth weight. Journal of Pediatric Biochemistry 2013;3:239-46.

 

2012

Bjørke-Monsen AL, Torsvik IK, Ueland PM, Sætran HA, Sandberg S. Increased yet iron-restricted erythropoiesis in postpartum mothers. Ann Hematol. 2012;91:1435-41.

Nilsen RM, Bjørke Monsen AL, Midttun Ø, Nygård O, Ulvik A, Magnus P,  Gjessing HK, Vollset SE, Ueland PM. Maternal Tryptophan and Kynurenine Pathway Metabolites and Risk of Preeclampsia. Obstet Gynecol. 2012;119:1243-50.

 

2011

Vugteveen I, Hoeksma M, Bjorke Monsen AL, Fokkema MR, Reijngoud DJ, van Rijn G, van Spronsen F. Serum vitamin B12 concentrations within reference values do not exclude functional vitamin B12 deficiency in PKU patients of various ages. Mol Genet Metab. 2011;102:13-7.

 

2010

Bjørke Monsen AL, Ueland PM. Cobalamin status in children. Journal of Inherited Metabolic Disease, 2010; 34:111-9.

Nilsen RM, Vollset SE, Bjørke Monsen AL, Ulvik A, Haugen M, Meltzer HM, Magnus P, Ueland PM. Infant Birth Size Is Not Associated with Maternal Intake and Status of Folate during Second Trimester in Norwegian Pregnant Women. J Nutr. 2010;140:572-9.

Publications related to cardiology and circulation

2014

Berg A, Bråtane E, Odland HH, Brudvik C, Rosland B, Hirth A. [Cardiovascular risk assessment for the use of ADHD drugs in children]. Tidsskr Nor Laegeforen. 2014 Apr 8;134(7):710-4.

 

2013

Berg A, Greve G. Trends in pediatric imaging: ultrasound. Acta Radiol. 2013 Nov;54(9):1096-105.

Cuypers J, Leirgul E, Larsen TH, Berg A, Omdal TR, Greve G. Assessment of vascular reactivity in the peripheral and coronary arteries by Cine 3T-magnetic resonance imaging in young normotensive adults after surgery for coarctation of the aorta. Pediatr Cardiol. 2013 Mar;34(3):661-9.

Tøndel C, Bostad L, Larsen KK, Hirth A, Vikse BE, Houge G, Svarstad E. Agalsidase benefits renal histology in young patients with Fabry disease. J Am Soc Nephrol. 2013 Jan;24(1):137-48.

Sandvik MK, Leirgul E, Nygård O, Ueland PM, Berg A, Svarstad E, Vikse BE. Preeclampsia in healthy women and endothelial dysfunction 10 years later. Am J Obstet Gynecol. 2013 Dec;209(6):569.e1-569.e10.

Sivertsen TB, Astrøm AN, Greve G, Aßmus J, Skeie MS. Endocarditis prophylaxis  and congenital heart defects in the Norwegian Public Dental Service. Acta Paediatr. 2013 Jan;102(1):29-34.

 

2012

Cuypers J, Leirgul E, Samnøy S, Larsen TH, Berg A, Schulze-Neick I, Greve G. Assessment of coronary flow reserve in the coronary sinus by cine 3T-magnetic resonance imaging in young adults after surgery for tetralogy of Fallot. Pediatr Cardiol. 2012 Jan;33(1):65-74.

Guthe HJ, Nedrebø T, Tenstad O, Wiig H, Berg A. Effect of topical anaesthetics on interstitial colloid osmotic pressure in human subcutaneous tissue sampled by wick technique. PLoS One. 2012;7(2):e31332.

Hirth A, Edwards NC, Greve G, Tangeraas T, Gerdts E, Lenes K, Norgård G. Left  ventricular function in children and adults after renal transplantation in childhood. Pediatr Nephrol. 2012 Sep;27(9):1565-74.

Instebø A, Helgheim V, Greve G. Repeatability of blood pressure measurements during treadmill exercise. Blood Press Monit. 2012 Apr;17(2):69-72.

Klausen SH, Mikkelsen UR, Hirth A, Wetterslev J, Kjærgaard H, Søndergaard L, Andersen LL. Design and rationale for the PREVAIL study: effect of e-Health individually tailored encouragements to physical exercise on aerobic fitness among adolescents with congenital heart disease--a randomized clinical trial. Am Heart J. 2012 Apr;163(4):549-56.

Trønnes H, Berg A. [Cardiac arrest in a 10-month-old boy with spinal cord injury]. Tidsskr Nor Laegeforen. 2012 May 15;132(9):1099-102.

 

2011

Houge G, Tøndel C, Kaarbøe O, Hirth A, Bostad L, Svarstad E. Fabry or not Fabry--a question of ascertainment. Eur J Hum Genet. 2011 Nov;19(11):1111.

Ueland T, Aukrust P, Omdal TR, Damås JK, Endresen K, Ren F, Hysing J. Effect of eptifibatide on platelet-mediated inflammation in acute coronary syndromes. Int J Cardiol. 2011 Sep 15;151(3):385-7.

Trewick AL, Moustafa JS, de Smith AJ, Froguel P, Greve G, Njølstad PR, Coin LJ, Blakemore AI. Accurate single-nucleotide polymorphism allele assignment in trisomic or duplicated regions by using a single base-extension assay with MALDI-TOF mass spectrometry. Clin Chem. 2011 Aug;57(8):1188-95.

Tangeraas T, Midtvedt K, Cvancarova M, Hirth A, Fredriksen PM, Tonstad S, Isaksen GA, Bjerre A. Cardiorespiratory fitness in young adults with a history of renal transplantation in childhood. Pediatr Nephrol. 2011 Nov;26(11):2041-9.

 

2010

Berg A, Furu K, Einen M, Spigset O. [Should children be treated with ephedrine mixture?]. Tidsskr Nor Laegeforen. 2010 Dec 16;130(24):2474-5

 

2009

Hamang A, Solberg B, Bjorvatn C, Greve G, Øyen N. [Genetic counseling in congenital long QT syndrome]. Tidsskr Nor Laegeforen. 2009 Jun 11;129(12):1226-9.

Hirth A, Disney P, Thorne S. Brain abscess associated with an unusual cause of right to left shunt. BMJ Case Rep. 2009;2009:bcr2006093773.

 Meberg A, Andreassen A, Brunvand L, Markestad T, Moster D, Nietsch L, SilbergIE, Skålevik JE. Pulse oximetry screening as a complementary strategy to detect critical congenital heart defects. Acta Paediatr. 2009 Apr;98(4):682-6.

Publications related to pregnancy and childbirth

2014

Kessler J, Moster D, Albrechtsen S. Intrapartum monitoring with cardiotocography and ST-waveform analysis in breech presentation: an observational study. BJOG. 2014 Jul 18. [Epub ahead of print] PubMed PMID: 25040705.

 

2013

Kessler J, Moster D, Albrechtsen S. Delay in intervention increases neonatal morbidity in births monitored with cardiotocography and ST-waveform analysis. Acta Obstet Gynecol Scand. 2013 Nov 19. doi: 10.1111/aogs.12304. [Epub ahead of print] PubMed PMID: 24251909.

Kessler J, Moster D, Albrechtsen S. Intrapartum monitoring of high-risk deliveries with ST analysis of the fetal electrocardiogram: an observational study of 6010 deliveries. Acta Obstet Gynecol Scand. 2013 Jan;92(1):75-84.

 

2008

Moster D. [Home childbirth--safe enough for the mother and the child?]. Tidsskr Nor Laegeforen. 2008 Nov 6;128(21):2430. Norwegian.

Publications related to orthopedic conditions

2014

Laborie LB, Markestad TJ, Davidsen H, Brurås KR, Aukland SM, Bjørlykke JA, Reigstad H, Indrekvam K, Lehmann TG, Engesæter IØ, Engesæter LB, Rosendahl K. Selective ultrasound screening for developmental hip dysplasia: effect on management and late detected cases. A prospective survey during 1991-2006. Pediatr Radiol. 2014 Apr;44(4):410-24.

 

2013

Rafaelsen SH, Raeder H, Fagerheim AK, Knappskog P, Carpenter TO, Johansson S,  Bjerknes R. Exome sequencing reveals FAM20c mutations associated with fibroblast  growth factor 23-related hypophosphatemia, dental anomalies, and ectopic calcification. J Bone Miner Res. 2013 Jun;28(6):1378-85.

 

2011

Brurås KR, Aukland SM, Markestad T, Sera F, Dezateux C, Rosendahl K. Newborns with sonographically dysplastic and potentially unstable hips: 6-year follow-up of an RCT. Pediatrics. 2011 Mar;127(3):e661-6.

Brurås KR, Aukland SM, Markestad T, Sera F, Dezateux C, Rosendahl K. Newborns with sonographically dysplastic and potentially unstable hips: 6-year follow-up of an RCT. Pediatrics. 2011 Mar;127(3):e661-6.

 

2010

Rosendahl K, Dezateux C, Fosse KR, Aase H, Aukland SM, Reigstad H, Alsaker T, Moster D, Lie RT, Markestad T. Immediate treatment versus sonographic surveillance for mild hip dysplasia in newborns. Pediatrics. 2010 Jan;125(1):e9-16.

Publications related to growth and weight

2014

Brannsether B, Eide GE, Roelants M, Bjerknes R, Júlíusson PB.Interrelationships between anthropometric variables and overweight in childhood and adolescence. Am J Hum Biol. 2014 Apr 30. doi: 10.1002/ajhb.22554. [Epub ahead of print] PubMed PMID: 24782200.

Glavin K, Roelants M, Strand BH, Júlíusson PB, Lie KK, Helseth S, Hovengen R. Important periods of weight development in childhood: a population-based longitudinal study. BMC Public Health. 2014;14:160.  PMID 24524269

 

2013

Danielsen YS, Nordhus IH, Júlíusson PB, Mæhle M, Pallesen S. Effect of a family-based cognitive behavioural intervention on body mass index, self-esteem and symptoms of depression in children with obesity (aged 7-13): a randomized waiting list controlled trial. Obes Res Clin Pract. 2013;7:e116-e128. PMID: 24331773.

Brannsether B, Roelants M, Bjerknes R, Júlíusson PB. References and cutoffs for triceps and subscapular skinfolds in Norwegian children 4-16 years of age. Eur J Clin Nutr. 2013;67:928-33. PMID:23632751

Júlíusson PB, Roelants M, Nordal E, Furevik L, Eide GE, Moster D, Hauspie R,  Bjerknes R. Growth references for 0-19 year-old Norwegian children for  length/height, weight, body mass index and head circumference. Ann Hum Biol. 2013;40:220-7. PMID:23414181.

Kristiansen H, Júlíusson PB, Eide GE, Roelants M, Bjerknes R. TV viewing and  obesity among Norwegian children: the importance of parental education. Acta Paediatr. 2013;102:199-205. PMID:23121043

 

2012

Kokkvoll A, Jeppesen E, Juliusson PB, Flaegstad T, Njølstad I. High prevalence of overweight and obesity among 6-year-old children in Finnmark County, North Norway. Acta Paediatr. 2012;101:924-8. PMID:22591105.

Milani S, Buckler JM, Kelnar CJ, Benso L, Gilli G, Nicoletti I, Faglia G, Radetti G, Bona G, Schonbeck Y, Van Buuren S, Hermanussen M, Grugni G, Marazzi N, Júlíusson PB, Roelants M, Hoppenbrouwers K, Hauspie R, Bjerknes R, Lejarraga H, Sartorio A. The use of local reference growth charts for clinical use or a universal standard: a balanced appraisal. J Endocrinol Invest. 2012;35:224-6. PMID:22490992.

Dahlseng MO, Andersen GL, DA Graca Andrada M, Arnaud C, Balu R, De la Cruz J, Folha T, Himmelmann K, Horridge K, Júlíusson PB, Påhlman M, Rackauskaite G, Sigurdardottir S, Uldall P, Vik T; Surveillance of Cerebral Palsy in Europe Network. Gastrostomy tube feeding of children with cerebral palsy: variation across six European countries. Dev Med Child Neurol. 2012;54:938-44.

Dahlseng MO, Finbråten AK, Júlíusson PB, Skranes J, Andersen G, Vik T. Feeding problems, growth and nutritional status in children with cerebral palsy. Acta Paediatr 2012;101:92-8

Grundt JH, Nakling J, Eide GE, Markestad T. Possible relation between maternal consumption of added sugar and sugar-sweetened beverages and birth weight--time trends in a population. BMC Public Health. 2012 Oct 24;12:901. PMID: 2309517.

Vollrath ME, Hampson SE, Júlíusson PB. Children and eating. Personality and gender are associated with obesogenic food consumption and overweight in 6- to 12-year-olds. Appetite. 2012;58:1113-7. PMID:22425617

 

2011

Brannsether B, Roelants M, Bjerknes R, Júlíusson PB. Waist circumference and  waist-to-height ratio in Norwegian children 4-18 years of age: reference values and cut-off levels. Acta Paediatr. 2011;100:1576-82. PMID:21627692

Danielsen YS, Júlíusson PB, Nordhus IH, Kleiven M, Meltzer HM, Olsson SJ, Pallesen S. The relationship between life-style and cardio-metabolic risk indicators in children: the importance of screen time. Acta Paediatr. 2011;100:253-9. PMID:21126262

Bang P, Bjerknes R, Dahlgren J, Dunkel L, Gustafsson J, Juul A, Kriström B, Tapanainen P, Aberg V. A comparison of different definitions of growth response in short prepubertal children treated with growth hormone. Horm Res Paediatr. 2011;75(5):335-45.

Júlíusson PB, Roelants M, Markestad T, Bjerknes R. Parental perception of overweight and underweight in children and adolescents. Acta Paediatr. 2011;100:260-5. PMID:20973817

 

2010

Júlíusson PB, Eide GE, Roelants M, Waaler PE, Hauspie R, Bjerknes R. Overweight and obesity in Norwegian children: prevalence and socio-demographic risk factors. Acta Paediatr. 2010;99:900-5. PMID:20175763.

Westerberg AC, Henriksen C, Ellingvåg A, Veierød MB, Júlíusson PB, Nakstad B, Aurvåg AK, Rønnestad A, Grønn M, Iversen PO, Drevon CA. First year growth among very low birth weight infants. Acta Paediatr. 2010;99:556-62. PMID:20096031

Júlíusson PB, Roelants M, Hoppenbrouwers K, Hauspie R, Bjerknes R. Growth of  Belgian and Norwegian children compared to the WHO growth standards: prevalence below -2 and above +2 SD and the effect of breastfeeding. Arch Dis Child. 2011;96:916-21. PMID:19948662

Tjora E, Karlsen LC, Moster D, Markestad T. Early severe weight loss in newborns after discharge from regular nurseries. Acta Paediatr. 2010 May;99(5):654-7.

 

2009

Júlíusson PB, Roelants M, Eide GE, Moster D, Juul A, Hauspie R, Waaler PE, Bjerknes R. [Growth references for Norwegian children]. Tidsskr Nor Laegeforen.2009;129:281-6. PMID:19219092

Publications related to neurosensory diseases and mental health

2014

Tollånes MC, Wilcox AJ, Lie RT, Moster D. Familial risk of cerebral palsy: population based cohort study. BMJ. 2014 Jul 15;349:g4294.

 

2013

Elgen I, Hikmat O, Aspevik TN, Hagen EM. CFS in Children and Adolescent: Ten Years of Retrospective Clinical Evaluation. Int J Pediatr. 2013;2013:270373. doi: Epub 2013 Jun 16. PubMed PMID: 23843800.

Bjorgaas HM, Elgen I, Boe T, Hysing M. Mental health in children with cerebral palsy: does screening capture the complexity? ScientificWorldJournal. 2013 Apr 3;2013:468402. Print 2013. PubMed PMID: 23690745.

Eide MG, Moster D, Irgens LM, Reichborn-Kjennerud T, Stoltenberg C, Skjærven R, Susser E, Abel K. Degree of fetal growth restriction associated with schizophrenia risk in a national cohort. Psychol Med. 2013 Oct;43(10):2057-66.

 

2012

Duric NS, Assmus J, Gundersen D, Elgen IB. Neurofeedback for the treatment of children and adolescents with ADHD: a randomized and controlled clinical trial using parental reports. BMC Psychiatry. 2012 Aug 10;12:107. PubMed PMID: 22877086.

Bjorgaas HM, Hysing M, Elgen I. Psychiatric disorders among children with cerebral palsy at school starting age. Res Dev Disabil. 2012 Jul-Aug;33(4):1287-93.

 

2011

Duric NS, Elgen I. Characteristics of Norwegian children suffering from ADHD  symptoms: ADHD and primary health care. Psychiatry Res. 2011 Aug 15;188(3):402-5.

Brodwall KM, Júlíusson PB, Bjerknes R, Hovland R, Fiskerstrand T.[Trichorhinophalangeal syndrome--clinical presentation and genetics]. Tidsskr Nor  Laegeforen. 2011 Aug 9;131(15):1420-3.

Hagen EM, Eide GE, Elgen I. Traumatic spinal cord injury among children and adolescents; a cohort study in western Norway. Spinal Cord. 2011 Sep;49(9):981-5.

 

2010

Moster D, Wilcox AJ, Vollset SE, Markestad T, Lie RT. Cerebral palsy among term and postterm births. JAMA. 2010 Sep 1;304(9):976-82.

 Ryland HK, Lundervold AJ, Elgen I, Hysing M. Is there a protective effect of normal to high intellectual function on mental health in children with chronic illness? Child Adolesc Psychiatry Ment Health. 2010 Jan 20;4:3. PMID: 20180976.

 

2009

Sivertsen B, Hysing M, Elgen I, Stormark KM, Lundervold AJ. Chronicity of sleep problems in children with chronic illness: a longitudinal population-based  study. Child Adolesc Psychiatry Ment Health. 2009 Aug 27;3(1):22. PMID: 19712458.

Hysing M, Elgen I, Gillberg C, Lundervold AJ. Emotional and behavioural problems in subgroups of children with chronic illness: results from a large-scale population study. Child Care Health Dev. 2009 Jul;35(4):527-33.

Sandtorv L, Reigstad H, Bruarøy S, Elgen I, Laegreid LM. [Substitution treatment of drug addicts during pregnancy: consequences for the children?]. Tidsskr Nor Laegeforen. 2009 Feb 12;129(4):287-90.

Hysing M, Sivertsen B, Stormark KM, Elgen I, Lundervold AJ. Sleep in children with chronic illness, and the relation to emotional and behavioral problems—a population-based study. J Pediatr Psychol. 2009 Jul;34(6):665-70.

Publications related to respiratory diseases not due to prematurity

2014

Mikalsen IB, Halvorsen T, Øymar K. Eosinophilia in bronchiolitis is related to bronchial hyperreactivity and lung function in adolescence..Acta Paediatr 2014;103:86-92.

 

2013

Andersen T, Sandnes A, Hilland M, Halvorsen T, Fondenes O, Heimdal JH, Tysnes OB, Røksund OD. Laryngeal Response Patterns to Mechanical Insufflation-Exsufflation in Healthy Subjects. Am J Phys Med Rehabil. 2013;92:920-9.

Bjørke-Monsen A-L, Halvorsen T, Midttun Ø, Ueland PM. Increased inflammatory markers in adolescents born extremely preterm and small for gestational age. Journal of Pediatric Biochemistry 2013;3:

Mikalsen IB, Halvorsen T, Øymar K. Exhaled nitric oxide is related to atopy, but not asthma in adolescents with previous bronchiolitis in infancy and controls.  BMC Pulm Med. 2013; 13:66 doi: 10.1186/1471-2466-13-66.

Sandnes A, Andersen T, Hilland M, Halvorsen T, Heimdal JH, Røksund OD.

Laryngeal movements during inspiratory muscle training in healthy subjects. J. Voice. 2013; 27:448-53.

Mikalsen IB, Halvorsen T, Eide GE, Øymar K.Severe bronchiolitis in infancy: Can asthma in adolescence be predicted? Pediatr Pulmonol. 2013;48:538-44.

Mikalsen IB, Halvorsen T, Oymar K.The optimal management of patients. (LETTER). Pediatric Pulmonology 2013; 48:936

Satrell E, Røksund OD, Thorsen E, and Halvorsen T.Pulmonary gas transfer in children and adolescents born extremely preterm. European Respiratory Journal. 2013;42:1536-44.

 

2012

Mikalsen IB, Halvorsen T, and Øymar K.The outcome after severe bronchiolitis is related to gender and virus. Pediatr Allergy Immunol 2012;23):391-8.

 

2011

Halvorsen T, Røksund O, Olofsson J, and Heimdal JH. Larynx in exercising humans; the unexplored bottleneck of the airways (LETTER). Pediatrics 2011;128 (6).

Heimdal JH, Halvorsen T, Maat RC, Røksund OD and Olofsson J. Exercise induced laryngeal obstruction (EILO): Diagnosis and Management. ENT Masterclass 2011;4: 117-123.

Halvorsen T, Røksund OD, Maat RC, and Heimdal JH. Use of post-exercise laryngoscopy to evaluate exercise induced dyspnea (LETTER). Pediatric Pulmonology, 2011 Feb 17.

Maat RC, Hilland M, Røksund OD, Halvorsen T, Olofsson J, Aarstad HJ, Heimdal H.Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment. Eur Arch Otorhinolaryngol. 2011 Oct;268(10):1485-92.

 

2009

Øymar K, Halvorsen T.Emergency presentation and management of acute severe asthma in children.Invited review. Scand J Trauma Resusc Emerg Med., 2009 Sep 4;17(1):40.

Maat RC, Røksund OD, Halvorsen T, Skadberg BT, Olofsson J, Ellingsen TA, Aarstad HJ, and Heimdal JH. Audiovisual assessment of exercise-induced laryngeal obstruction: reliability and validity of observations. Eur Arch Otorhinolaryngol.2009;266:1929-36.

Røksund OD, Maat RC, Heimdal JH, Olofsson J, Skadberg BT, Halvorsen T. Exercise induced dyspnea in the young. Larynx as the bottleneck of the airways. Respiratory Medicine, 2009;103:1911-8.

Publications related to prematurity

2014

Husebye ES, Kleven IA, Kroken LK, Torsvik IK, Haaland OA, Markestad T. Targeted Program for Provision of Mother's Own Milk to Very Low Birth Weight Infants. Pediatrics. 2014;134:e489-95.

Griffiths ST, Aukland SM, Markestad T, Eide GE, Elgen I, Craven AR, Hugdahl K. Association between brain activation (fMRI), cognition and school performance in extremely preterm and term born children. Scand J Psychol. 2014 Jul 9. [Epub ahead of print]

Trønnes H, Wilcox AJ, Lie RT, Markestad T, Moster D. Risk of cerebral palsy in relation to pregnancy disorders and preterm birth: a national cohort study. Dev Med Child Neurol. 2014;56:779-85.

Clemm HH, Vollsæter M, Røksund OD, Eide GE, Markestad T, Halvorsen T. Exercise Capacity after Extremely Preterm Birth: Development from Adolescence toAdulthood. Ann Am Thorac Soc. 2014 Feb 6. [Epub ahead of print].

 

2013

Trønnes H, Wilcox AJ, Lie RT, Markestad T, Moster D. The association of preterm birth with severe asthma and atopic dermatitis: a national cohort study. Pediatr Allergy Immunol. 2013 Dec;24(8):782-7. doi: 10.1111/pai.12170. Epub 2013  Dec 2. PubMed PMID: 24298940;

Aukland SM, Elgen IB, Odberg MD, Chong WK, Eide GE, Rosendahl K. Ventricular dilatation in ex-prematures: only confined to the occipital region? MRI-based normative standards for 19-year-old ex-prematures without major handicaps. ActaRadiol. 2014 May 1;55(4):470-7.

Griffiths ST, Elgen IB, Chong WK, Odberg MD, Markestad T, Neto E, Aukland SM. Cerebral magnetic resonance imaging findings in children born extremely preterm, very preterm, and at term. Pediatr Neurol. 2013 Aug;49(2):113-8.

Griffiths ST, Gundersen H, Neto E, Elgen I, Markestad T, Aukland SM, Hugdahl K. fMRI: blood oxygen level-dependent activation during a working memory-selective attention task in children born extremely preterm. Pediatr Res. 2013 Aug;74(2):196-205.

Vollsæter M, Røksund OD, Eide GE, Markestad T, Halvorsen T. Lung function after preterm birth: development from mid-childhood to adulthood. Thorax. 2013 Aug;68(8):767-76.

Eger SH, Sommerfelt K, Kiserud T, Markestad T. Foetal umbilical artery Doppler in small preterms: (IQ) neurocognitive outcome at 5 years of age. Acta Paediatr. 2013 Apr;102(4):403-9.

 

2012

Vederhus BJ, Eide GE, Natvig GK, Markestad T, Graue M, Halvorsen T. Pain tolerance and pain perception in adolescents born extremely preterm. J Pain. 2012 Oct;13(10):978-87

Elgen IB, Holsten F, Odberg MD. Psychiatric disorders in low birthweight young adults. Prevalence and association with assessments at 11 years. Eur Psychiatry. 2013 Sep;28(7):393-6.

Elgen SK, Leversen KT, Grundt JH, Hurum J, Sundby AB, Elgen IB, Markestad T. Mental health at 5 years among children born extremely preterm: a national population-based study. Eur Child Adolesc Psychiatry. 2012 Oct;21(10):583-9.

Clemm H, Røksund O, Thorsen E, Eide GE, Markestad T, Halvorsen T. Aerobic capacity and exercise performance in young people born extremely preterm.Pediatrics. 2012 Jan;129(1):e97-e105.

Leversen KT, Sommerfelt K, Elgen IB, Eide GE, Irgens LM, Júlíusson PB, Markestad T. Prediction of outcome at 5 years from assessments at 2 years among extremely preterm children: a Norwegian national cohort study. Acta Paediatr.2012 Mar;101(3):264-70.

 

2011

Leversen KT, Sommerfelt K, Rønnestad A, Kaaresen PI, Farstad T, Skranes J, Støen R, Bircow Elgen I, Rettedal S, Egil Eide G, Irgens LM, Markestad T. Prediction of neurodevelopmental and sensory outcome at 5 years in Norwegian children born extremely preterm. Pediatrics. 2011 Mar;127(3):e630-8.

Odberg MD, Elgen IB. Low birth weight young adults: quality of life, academic achievements and social functioning. Acta Paediatr. 2011 Feb;100(2):284-8.

Aukland SM, Westerhausen R, Plessen KJ, Odberg MD, Elgen IB, Peterson BS, Ersland L, Eide GE, Rosendahl K. Selectively reduced posterior corpus callosum size in a population-based sample of young adults born with low birth weight. AJNR Am J Neuroradiol. 2011 May;32(5):970-5.

 

2010

Røksund OD, Clemm H, Heimdal JH, Aukland SM, Sandvik L, Markestad T, Halvorsen T. Left vocal cord paralysis after extreme preterm birth, a new clinical scenario in adults. Pediatrics. 2010 Dec;126(6):e1569-77.

Haugen OH, Nepstad L, Standal OA, Elgen I, Markestad T. Visual function in 6  to 7 year-old children born extremely preterm: a population-based study. Acta Ophthalmol. 2012 Aug;90(5):422-7.

Odberg MD, Aukland SM, Rosendahl K, Elgen IB. Cerebral MRI and cognition in nonhandicapped, low birth weight adults. Pediatr Neurol. 2010 Oct;43(4):258-62.

 Leversen KT, Sommerfelt K, Rønnestad A, Kaaresen PI, Farstad T, Skranes J, Støen R, Elgen IB, Rettedal S, Eide GE, Irgens LM, Markestad T. Predicting neurosensory disabilities at two years of age in a national cohort of extremely premature infants. Early Hum Dev. 2010 Sep;86(9):581-6.

Farstad T, Bratlid D, Medbø S, Markestad T; Norwegian Extreme Prematurity Study Group. Bronchopulmonary dysplasia - prevalence, severity and predictive factors in a national cohort of extremely premature infants. Acta Paediatr. 2011 Jan;100(1):53-8.

 Vederhus BJ, Markestad T, Eide GE, Graue M, Halvorsen T. Health related quality of life after extremely preterm birth: a matched controlled cohort study. Health Qual Life Outcomes. 2010 May 23;8:53. PubMed  PMID: 20492724.

Odberg MD, Sommerfelt K, Markestad T, Elgen IB. Growth and somatic health until adulthood of low birthweight children. Arch Dis Child Fetal Neonatal Ed.2010 May;95(3):F201-5.

 

2009

Westby Wold SH, Sommerfelt K, Reigstad H, Rønnestad A, Medbø S, Farstad T, Kaaresen PI, Støen R, Leversen KT, Irgens LM, Markestad T. Neonatal mortality and morbidity in extremely preterm small for gestational age infants: a population based study. Arch Dis Child Fetal Neonatal Ed. 2009 Sep;94(5):F363-7.

Aukland SM, Rosendahl K, Owens CM, Fosse K, Eide GE, Halvorsen T. Neonatal bronchopulmonary dysplasia predicts abnormal pulmonary HRCT in long term survivors of extreme preterm birth. Thorax. 2009;64:405-410.

People

Group manager

Camilla Tøndel Professor, Head of Teaching

Group members

Robert Bjerknes Emeritus

Knut Asbjørn Alexander Øymar Professor

Ingvild Bruun Mikalsen Professor

Maria Vollsæter Associate Professor

Kristian Sommerfelt Emeritus

Elisabeth Ørskov Rotevatn PhD Candidate

Nina Hapnes PhD Candidate

Zuzana Huncikova PhD Candidate

Dag Moster Professor, Department of Global Public Health and Primary Care

Ingvild Halsør Forthun PhD Candidate

Bente Brannsether-Ellingsen Associate Professor

Praveen Muralitharan PhD Candidate

Thomas Halvorsen Professor

Gottfried Greve Professor

Pétur Benedikt Juliusson Professor

Hege Kristiansen Associate Professor

Trond Markestad Emeritus

Omar Hikmat Associate Professor

Jostein Andersen Førsvoll Associate Professor

Melissa Rajini Balthasar PhD Candidate

Mette Engan Guest Researcher

Eirik Volckmar Kaasa PhD Candidate

Anna Ingeborg Gundersen PhD Candidate

Peder Aleksander Bjorland Associate Professor

Contact

Visitor address
Haukeland universitetssykehus Jonas Lies vei 65
5021 Bergen

Postal address
P.O. Box 7804
NO-5020 Bergen
Norway

Phone number
+4792468362
Emails
camilla.tondel@uib.no