Nyreforskningsgruppen er et åpent forum for klinisk og translasjonell nyreforskning i Bergen. Nyreforskningsgruppen har tradisjonelt kombinert human- og dyremodeller for å studere sykdomsmekanismer, med avanserte molekylære analyser av nyrebiopsier og digital patologi. I tillegg gjennomføres både epidemiologiske studier av risikofaktorer og sykdomsutvikling ved kronisk nyresykdom i tillegg til flere pågående kliniske studier.

2020

• Øystein Solberg Eikrem; Nicolas Delaleu; Philipp Strauss et al. (2020). Systems Analyses of Renal Fabry Transcriptome and Response to Enzyme Replacement Therapy (ERT) Identifies a Cross-Validated and Druggable ERT-Resistant Module. (ekstern lenke)
• Tarek Mazzawi; Øystein Solberg Eikrem; Gülen Arslan Lied et al. (2020). Abnormal Uroguanylin Immunoreactive Cells Density in the Duodenum of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Changes following Fecal Microbiota Transplantation. (ekstern lenke)

2016

• Lea Zoe Landolt; Hans-Peter Marti; Christian Beisland et al. (2016). RNA extraction for RNA sequencing of archival renal tissues. (ekstern lenke)
• Lea Zoe Landolt; Øystein Solberg Eikrem; Gro Gausdal et al. (2016). Detection and Validation of Epithelial-to-Mesenchymal Transition(EMT) with Increased Expression of Axl and MMP-14 in Renal Cell Carcinoma. (ekstern lenke)
• Øystein Solberg Eikrem; Andreas Scherer; Lea Zoe Landolt et al. (2016). Development and Confirmation of Gene Classifiers of Human Clear Cell Renal Cell Carcinoma Using Next-Generation Sequencing [Abstract].. (ekstern lenke)
• Øystein Solberg Eikrem; Philipp Strauss; Christian Beisland et al. (2016). Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. (ekstern lenke)
• Lea Zoe Landolt; Philipp Strauss; Hans-Peter Marti et al. (2016). Next generation sequencing: A tool for this generation of nephrologists. (ekstern lenke)
• Øystein Solberg Eikrem; Christian Beisland; Karin Margrethe Hjelle et al. (2016). Transcriptome sequencing (RNAseq) enables utilization of formalin-fixed, paraffin-embedded biopsies with clear cell renal cell carcinoma for exploration of disease biology and biomarker development. (ekstern lenke)

2019

• Even Koch; Kenneth Finne; Øystein Solberg Eikrem et al. (2019). Transcriptome-proteome integration of archival human renal cell carcinoma biopsies enables identification of molecular mechanisms. (ekstern lenke)
• Lea Zoe Landolt; Jessica Furriol; Janka Babickova et al. (2019). AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. (ekstern lenke)
• Philipp Strauss; Øystein Solberg Eikrem; Camilla Tøndel et al. (2019). Fabry Nephropathy: First mRNA-seq Findings from Kidney Biopsies Before and After Enzyme Replacement Therapy. (ekstern lenke)
• Øystein Solberg Eikrem; Hans-Peter Marti (2019). New methods clear the dust off old biopsies. RNA sequencing of FFPE kidney biopsies. (ekstern lenke)

2023

• Nicolas Delaleu; Hans Peter Marti; Philipp Strauss et al. (2023). Systems analyses of the Fabry kidney transcriptome and its response to enzyme replacement therapy identified and cross-validated enzyme replacement therapy-resistant targets amenable to drug repurposing. (ekstern lenke)
• Ole Petter Nordbø; Lea Zoe Landolt; Øystein Solberg Eikrem et al. (2023). Transcriptomic analysis reveals partial epithelial–mesenchymal transition and inflammation as common pathogenic mechanisms in hypertensive nephrosclerosis and Type 2 diabetic nephropathy. (ekstern lenke)
• Mariell Lossius Rivedal; Håvard Mikkelsen; Hans Peter Marti et al. (2023). Glomerular transcriptomics predicts long term outcome and identifies therapeutic strategies for patients with assumed benign IgA nephropathy. (ekstern lenke)
• Hassan Osman Alhassan Elsaid; Mariell Lossius Rivedal; Eleni Skandalou et al. (2023). Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla ^−/− zebrafish model of Fabry disease. (ekstern lenke)
• Philipp Strauss; Øystein Solberg Eikrem; Hans Peter Marti et al. (2023). From archival tissues to systems biology: Using transcriptomics to investigate the progression of kidney disease. (ekstern lenke)
• Øystein Solberg Eikrem; Bjørnar Sandnes Lillefosse; Nicolas Delaleu et al. (2023). Network-Based Assessment of Minimal Change Disease Identifies Glomerular Response to IL-7 and IL-12 Pathways Activation as Innovative Treatment Target. (ekstern lenke)
• Miroslav Sekulic; Ibrahim Batal; Satoru Kudose et al. (2023). Kidney Dysfunction and Pathology in the Setting of Hemophagocytic Lymphohistiocytosis. (ekstern lenke)
• Fabian Braun; Ahmed Abed; Dominik Sellung et al. (2023). Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy. (ekstern lenke)

2021

• Sigrid Nakken; Øystein Solberg Eikrem; Hans Peter Marti et al. (2021). AGAP2-AS1 as a prognostic biomarker in low-risk clear cell renal cell carcinoma patients with progressing disease. (ekstern lenke)
• Fabian Braun; Ahmed Abed; Mathias Woidy et al. (2021). Synuclein Alpha Accumulation Drives Lysosomal Dysfunction in Fabry Podocytopathy. (ekstern lenke)
• Øystein Solberg Eikrem; Spiros Kotopoulis; Mihaela-Lucia Popa et al. (2021). Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys. (ekstern lenke)

2017

• Lea Zoe Landolt; Øystein Solberg Eikrem; Philipp Strauss et al. (2017). Clear cell renal cell carcinoma is linked to epithelial-to-mesenchymal transition and to fibrosis. (ekstern lenke)
• Einar Svarstad; Sabine Maria Leh; Rannveig Skrunes et al. (2017). Bedside stereomicroscopy of Fabry kidney biopsies: An easily available method for diagnosis and assessment of sphingolipid deposits. (ekstern lenke)
• Øystein Solberg Eikrem; Rannveig Skrunes; Camilla Tøndel et al. (2017). Pathomechanisms of renal Fabry disease. (ekstern lenke)

2025

• Tony Jialiang Chen; Eleni Skandalou; Katarina Fritz-Wallace et al. (2025). Serum proteome analysis detects early molecular signatures of disease progression in IgA nephropathy. (ekstern lenke)
• Simen Femanger Pettersen; Eleni Skandalou; Jessica Furriol Palmer et al. (2025). Reconstruction of Single-Cell Spatial Transcriptomes in Archival Kidney Biopsies. (ekstern lenke)
• Marius Altern Øvrehus; Knut Asbjørn Rise Langlo; Sabine Leh et al. (2025). Correction to: Norwegian kidney biopsy biobank (NorKiBB): organization, baseline characteristics, and generalizability of a low-cost national biobank (BMC Nephrology, (2025), 26, 1, (76), 10.1186/s12882-025-04007-4). (ekstern lenke)
• Mariell Lossius Rivedal; Ole Petter Nordbø; Yngvar Lunde Haaskjold et al. (2025). Lifetime progression of IgA nephropathy: a retrospective cohort study with extended long-term follow-up. (ekstern lenke)
• Ole Petter Nordbø; Øystein Solberg Eikrem; Philip A. Kalra et al. (2025). Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression. (ekstern lenke)
• Marius Altern Øvrehus; Knut Asbjørn Rise Langlo; Sabine Leh et al. (2025). Norwegian kidney biopsy biobank (NorKiBB): organization, baseline characteristics, and generalizability of a low-cost national biobank. (ekstern lenke)

2022

• Håvard Mikkelsen; Bjørn Egil Vikse; Øystein Solberg Eikrem et al. (2022). Glomerular proteomic profiling of kidney biopsies with hypertensive nephropathy reveals a signature of disease progression. (ekstern lenke)
• Hassan Osman Alhassan Elsaid; Håkon Tjeldnes; Mariell Lossius Rivedal et al. (2022). Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca²⁺ Signaling Similar to Fabry Disease. (ekstern lenke)
• Philipp Strauss; Mariell Rivedal; Andreas Scherer et al. (2022). A multiomics disease progression signature of low-risk ccRCC. (ekstern lenke)

2018

• Øystein Solberg Eikrem; Tedd Christian Walther; Arnar Flatberg et al. (2018). Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys. (ekstern lenke)
• Philipp Strauss; Hans-Peter Marti; Christian Beisland et al. (2018). Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma. (ekstern lenke)
• Even Evjen Koch; Øystein Solberg Eikrem; Arnar Flatberg et al. (2018). Fine needle aspirates of kidneys are usable for RNA sequencing like regular core biopsies. (ekstern lenke)
• Philipp Strauss; Even Evjen Koch; Hans-Peter Marti et al. (2018). Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasability of miRNA-sequencing for disease exploration and biomarker development from biopsies with clear cell renal cell carcinoma. (ekstern lenke)
• Øystein Solberg Eikrem; Even Evjen Koch; Thomas Knoop et al. (2018). Primary Membranous Nephropathy: Glomerular RNA Sequencing from Archival Kidney Biopsies. (ekstern lenke)
• Øystein Solberg Eikrem; Hans-Peter Marti (2018). Klarcellet nyrekarsinom er knyttet til epitelial-til- mesenkymal overgang (EMT) og til fibrose. (ekstern lenke)
• Øystein Solberg Eikrem; Philipp Strauss; Miroslav Sekulic et al. (2018). Fabry nephropathy: Transcriptome sequencing of microdissected renal compartments from archival kidney biopsies at baseline, and after 5 & 10 years of enzyme replacement therapy. (ekstern lenke)

2024

• Mariell Lossius Rivedal; Yngvar Lunde Haaskjold; Øystein Solberg Eikrem et al. (2024). Use of corticosteroids in Norwegian patients with immunoglobulin a nephropathy progressing to end-stage kidney disease: a retrospective cohort study. (ekstern lenke)

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