Forskergrupper
Kort info
Publikasjoner
Vitenskapelig artikkel
- August Hoel; Fredrik Hoel; Sissel Dyrstad et al. (2026). Charting the circulating proteome in ME/CFS using cross-system profiling to uncover mechanistic insights. (ekstern lenke)
- Sissel Elisabeth Dyrstad; Maria Lie Lotsberg; Tuan Zea Tan et al. (2021). Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with EGFR TKI and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells. (ekstern lenke)
- Øystein Fluge; Olav Mella; Ove Bruland et al. (2016). Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome.. (ekstern lenke)
- Maria Lie Lotsberg; Gro Vatne Røsland; Austin James Rayford et al. (2022). Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models. (ekstern lenke)
- Magali R Van Linden; Christian Dölle; Ina Katrine Nitschke Pettersen et al. (2015). Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells. (ekstern lenke)
- Ina Katrine Nitschke Pettersen; Deusdedit Tusubira; Hanan Ashrafi et al. (2019). Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation. (ekstern lenke)
- Sissel Elisabeth Dyrstad; Deusdedit Tusubira; Stian Knappskog et al. (2018). Introducing nano-scale quantitative polymerase chain reaction. (ekstern lenke)
- Gro Vatne Røsland; Sissel Elisabeth Dyrstad; Deusdedit Tusubira et al. (2019). Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.. (ekstern lenke)
- Sissel Dyrstad; Kimberley Joanne Hatfield; Endre Stigen et al. (2025). Mapping of Functional Metabolic Phenotypes in Acute Myeloid Leukemia. (ekstern lenke)
Vitenskapelig litteraturgjennomgang
Momentum Delegate 2026/2027
I am a researcher at the Departement of Biomedicine working to understand the immunological and metabolic mechanisms that drive post‑infectious diseases such as ME/CFS and Long Covid. My scientific background spans biomedicine, cancer metabolism, immunology, and clinical laboratory research.
ME/CFS and Long-Covid place a substantial burden on patients and healthcare systems, yet they remain without established biomarkers or effective treatments. My work aims to define the immunological and metabolic mechanisms that shape ME/CFS and related disorders. We use a translational research approach in which laboratory in vitro experiments are guided by data from patient samples, including multi-omics and extracellular particle analyses, to investigate mechanistic targets. My current focus is finding an autoimmune component in ME/CFS by analyzing patient blood samples collected before and after immunomodulatory treatment.
What drives me is the possibility of clarifying a disease that has been unclear for far too long and contributing to a better understanding of conditions that place a considerable burden on patients, families and healthcare systems. In the long run, I hope to develop knowledge and methodological approaches that can be useful not only in post infectious diseases, but also across research fields and diseases characterized by complex and poorly understood biology.