Forskningsgruppen for tropiske infeksjonssykdommer

1. Prevention of long covid-19 in Norway by treatment with Paxlovid (PANORAMIC).
2. The Coordination Mechanism for Cohorts and Trials (CoMeCT).

1. Probiotics as adjunct preventive therapy for childhood diarrhea and antimicrobial resistance in Africa (PRoRota)
2. Probiotic treatment of newborns to reduce colonization and disease caused by resistant bacteria (ProRIDE).

1. CAMRIA (Combatting Anti-Microbial Resistance with Interdisciplinary Approaches)
   • Surveillance and metagenomic tracking of antimicrobial resistance genes in environmental and clinical samples using machine learning approaches (MARGIN).
   • Learning and predicting the pathways of antimicrobial resistance evolution using hypercubic transition path sampling, computational and mathematical approach to learn evolutionary pathways using large-scale biological data (HyperEvol)
   • Risk communication and perception of antimicrobial resistance in the public and among healthcare workers: Knowledge needed to develop new policies and interventions (Media and AMR).
2. Antimicrobial stewardship in hospitals, resistance selection and transfer in a One Health context (STRESST).
3. Consequences of antibiotic resistance after preventive treatment with cotrimoxazole in HIV patients (CoTrimResist).
4. Innate and adaptive immunity within the early versus late BCG vaccination in HIV-1 exposed infants (BCGI).
5. Bloodstream infections and antibiotic resistance among patients in Tanzania.
6. Development of methods for detection of the malaria parasite’s genetic material.

1. Immune reasponse against Giardia in humans (Bergen Giardia Research Group).
2. Detection and prevalence of intestinal parasites in Norway, including genotyping of circulating Giardia and Cryptosporidium variants (TaDiGe).
3. Improved diagnostics for Cryptosporidium in low-income countries (Crypto-POC, CryptoT&T).
4. Exposure study to enterotoxigenic Escherichia coli bacteria and vaccine development (ETEC).
5. Causes of diarrhea among children under five years of age in Tanzania.

1. Investigation of the protocols for supportive treatment in Ebola treatment centers in Sierra Leone and other affected countries.
2. Evaluation of the efficacy of a post-exposure prophylaxis strategy in contacts at high risk of developing Ebola virus disease.

1. Bacterial strain colonization in fecal microbiota transfer therapy in patients with irritable bowel syndrome (STRACOL).
2. The significance of blood volume in blood cultures in children: evaluation of weight- and age-adjusted volumes for growth of pathogenic microbes and microbial contamination.

1. Developing vaccines against diarrhea caused by enterotoxigenic Shigella (EntVac)
2. Developing vaccines against diarrhea caused by enterotoxigenic Escherichia coli (ETECVac)
3. Transplantation of intestinal microbiota in primary Clostridioides difficile infections (COLONIZE)
4. Gastrointestinal complaints and fatigue among patients and a control group after the giardiasis outbreak in Bergen in 2004 (Bergen Giardia Research Group).

Her presenteres et utvalg av forskningsgruppens sentrale publikasjoner. For mer detaljerte publikasjonslister, se de enkelte prosjektsidene. 

1. Metabolic reprogramming of the infant gut by bifidobacteria-based probiotics drives exclusion of antibiotic-resistant pathobionts. (2026)
2. Evaluation of rectal swab compared with bulk stool sampling for detection of Cryptosporidium infection by light-emitting diode auramine-phenol microscopy in young children with diarrhoea. (2025)
3. Comparative genomics of blood and faecal E. coli and K. pneumoniae isolates from neonates with bloodstream infections in Tanzania. (2025)
4. Home administration of a multistrain probiotic once per day for 4 weeks to newborn infants in Tanzania (ProRIDE): a double-blind, placebo-controlled randomised trial. (2025)
5. Cryptosporidium species and subtypes in Norway: predominance of C. parvum and emergence of C. mortiferum. (2024)
6. Gut microbiota patterns associated with duration of diarrhea in children under five years of age in Ethiopia. (2024)
7. Predominance of multidrug-resistant Salmonella typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar. (2024)
8. Spatiotemporal variation in risk of Shigella infection in childhood: a global risk mapping and prediction model using individual participant data. (2023)
9. Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection. (2023)
10. Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia. (2022)
11. Long COVID in a prospective cohort of home-isolated patients. (2021)
12. Performance and operational feasibility of two diagnostic tests for cryptosporidiosis in children (CRYPTO-POC): a clinical, prospective, diagnostic accuracy study. (2020)

1. Annette Onken: Bloodstream infections and antimicrobial resistance in Zanzibar, Tanzania, with special focus on typhoid fever and malaria. (2024)
2. Øystein Haarklau Johansen: Cryptosporidiosis in low-resource healthcare settings. (2023)
3. Joel Manyahi: Molecular characterization of antibiotic resistant bacteria in newly HIV diagnosed adults in a community setting in Tanzania. Implications for infection prevention and control in HIV. (2022)
4. Christina Skår Saghaug: Genetic variability of proteins involved in metronidazole metabolism and detoxification in Giardia lamblia.​ (2021)
5. Thandile Nkosi: Severe anemia in Malawian children: Risk factors, mortality and malaria chemoprevention. (2021)
6. Sunniva Todnem Sakkestad: Enterotoxigenic Escherichia coli infection and diarrhoea - experimental infection studies and immunological characterisation to guide vaccine development. (2021)
7. Sabrina Moyo: Viral diarrhoea in children under two years of age in Dar es Salaam, Tanzania. (2014)
8. Gro Elizabeth Ann Strøm: Diagnosing pediatric malaria in Dar es Salaam, Tanzania. Clinical and laboratorial perspectives. (2014)
9. Kurt Hanevik: Post-giardiasis functional gastrointestinal disorders and chronic fatigue syndrome – clinical symptoms, inflammation and immune responses. (2012)
10. Kristine Mørch: Giardiasis : with emphasis on treatment and post-infectious manifestations. (2010)
11. Bjørn Blomberg: Antimicrobial resistance in bacterial infections in urban and rural Tanzania (2007)